JP6133858B2 - 創傷治癒組成物及び使用方法 - Google Patents

創傷治癒組成物及び使用方法 Download PDF

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Publication number
JP6133858B2
JP6133858B2 JP2014522919A JP2014522919A JP6133858B2 JP 6133858 B2 JP6133858 B2 JP 6133858B2 JP 2014522919 A JP2014522919 A JP 2014522919A JP 2014522919 A JP2014522919 A JP 2014522919A JP 6133858 B2 JP6133858 B2 JP 6133858B2
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Japan
Prior art keywords
composition
wound
tissue
phmb
wounds
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JP2014522919A
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English (en)
Japanese (ja)
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JP2014521649A5 (cg-RX-API-DMAC10.html
JP2014521649A (ja
Inventor
ジェイ．パークス パトリック
ジェイ．パークス パトリック
エル．ピーターソン マーニー
エル．ピーターソン マーニー
ジェイ．アンダーソン マイケル
ジェイ．アンダーソン マイケル
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3M Innovative Properties Co
University of Minnesota Twin Cities
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3M Innovative Properties Co
University of Minnesota System
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2053—IL-8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/206—Biguanides, e.g. chlorohexidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014522919A 2011-07-28 2012-07-23 創傷治癒組成物及び使用方法 Expired - Fee Related JP6133858B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161512655P 2011-07-28 2011-07-28
US61/512,655 2011-07-28
PCT/US2012/047786 WO2013016255A1 (en) 2011-07-28 2012-07-23 Wound-healing compositions and method of use

Publications (3)

Publication Number Publication Date
JP2014521649A JP2014521649A (ja) 2014-08-28
JP2014521649A5 JP2014521649A5 (cg-RX-API-DMAC10.html) 2015-09-10
JP6133858B2 true JP6133858B2 (ja) 2017-05-24

Family

ID=46601927

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014522919A Expired - Fee Related JP6133858B2 (ja) 2011-07-28 2012-07-23 創傷治癒組成物及び使用方法

Country Status (4)

Country Link
US (2) US20140194803A1 (cg-RX-API-DMAC10.html)
EP (1) EP2736486B1 (cg-RX-API-DMAC10.html)
JP (1) JP6133858B2 (cg-RX-API-DMAC10.html)
WO (1) WO2013016255A1 (cg-RX-API-DMAC10.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202014100305U1 (de) * 2013-12-23 2015-04-20 Nawa-Heilmittel Gmbh Transparentes Gel
US9848604B2 (en) 2014-07-11 2017-12-26 Medtronic Xomed, Inc. Antimicrobial wash
CN107073161B (zh) * 2014-10-01 2020-11-03 3M创新有限公司 用于清创术的多孔装置、套件和方法
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
US20160101166A1 (en) * 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
US9592280B2 (en) * 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US20180303873A1 (en) * 2014-12-04 2018-10-25 3M Innovative Properties Company Antimicrobial compositions comprising bioglass
WO2016123539A1 (en) 2015-01-29 2016-08-04 Wardell Mark R Wound healing compositions involving medicinal honey, mineral ions, and methylglyoxal, and methods of use
US10264788B2 (en) * 2015-12-30 2019-04-23 Carefusion 2200, Inc. Antimicrobial wipe
EP4487876A1 (en) 2023-07-07 2025-01-08 Leibniz-Institut für Polymerforschung Dresden e.V. Improved wound dressing and method to prepare it
EP4763235A1 (en) 2024-12-20 2026-06-24 ResCure GmbH Improved wound dressing and method to prepare it

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3416777C2 (de) * 1984-05-07 1986-11-20 Gödecke AG, 1000 Berlin Pharmazeutische topische Zubereitungen
US5080900A (en) 1990-04-17 1992-01-14 Stanley R Thomas Treatment of skin ulcers with an aqueous extract of oak bark ash
DK0668769T3 (da) * 1992-11-06 2000-10-02 Greystone Medical Group Inc Egebarkekstrakt-relaterede syntetiske sammensætninger og fremgangsmåde til deres anvendelse
US7014870B1 (en) 1992-11-06 2006-03-21 Greystone Medical Group, Inc. Compositions of oak bark extract related synthetic compositions and method of using same
US7923469B2 (en) * 2001-04-30 2011-04-12 Allergen, Inc. Compositions including vitamin-based surfactants and methods for using same
NZ533252A (en) * 2001-11-29 2006-03-31 Greystone Medical Group Inc Treatment of wounds and compositions employed
WO2004057965A1 (en) * 2002-12-23 2004-07-15 Greystone Medical Group, Inc. Reduction of reactive oxygen species in chronic wound management
CN102319409A (zh) * 2003-07-17 2012-01-18 纽约市哥伦比亚大学托管会 含有季铵化合物及精油和/或精油成分的协同组合的抗微生物组合物
CA2565556A1 (en) * 2004-05-03 2005-12-08 Neosil, Inc. Polycationic antimicrobial therapeutic
US20050249791A1 (en) * 2004-05-07 2005-11-10 3M Innovative Properties Company Antimicrobial articles
MX2007008905A (es) * 2005-01-28 2007-08-16 Procter & Gamble Diyodometil-p-tolil sulfona como una dispersion particulada en un solvente liquido.
WO2007056205A2 (en) * 2005-11-04 2007-05-18 Eastman Chemical Company Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents
DE102006001954B4 (de) * 2006-01-16 2013-01-03 Lohmann & Rauscher Gmbh & Co. Kg Antiseptische Alginatzubereitung, Verfahren zu deren Herstellung, sowie deren Verwendung
US20070264226A1 (en) * 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
WO2007143586A2 (en) * 2006-06-01 2007-12-13 Pharmaionx, Inc. Composition for wound care and method of using same
EP2234498A4 (en) * 2007-12-11 2011-02-16 Stephen H Monroe AQUEOUS BUFFER SOLVENT COMPOSITION FOR THE TREATMENT OF CELL ENVIRONMENT AND ION CHANNELS AND METHOD FOR THEIR USE

Also Published As

Publication number Publication date
US20140194803A1 (en) 2014-07-10
EP2736486A1 (en) 2014-06-04
EP2736486B1 (en) 2019-03-06
WO2013016255A1 (en) 2013-01-31
US20170112786A1 (en) 2017-04-27
JP2014521649A (ja) 2014-08-28

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