JP6114469B2 - 生理学的情報を抽出する装置、システム及び方法 - Google Patents
生理学的情報を抽出する装置、システム及び方法 Download PDFInfo
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Description
― 対象の皮膚領域を透過したか又はそこから反射された検出される電磁放射から得られる検出データのデータストリームを受ける入力インタフェースであって、検出データは、それぞれの波長部分を表す少なくとも2つの信号チャンネルにおける波長依存的な反射又は透過の情報を含む、入力インタフェース、
― 少なくとも2つの信号チャンネルを動的に混合して少なくとも1つの混合された信号にする信号ミキサ、
― 少なくとも1つの混合された信号から、少なくとも1つのバイタルサインを示す生理学的情報を得るプロセッサ、並びに、
― 信号ミキサを制御して、少なくとも1つの混合された信号に混合される少なくとも2つの信号チャンネルの相対寄与、及び/又は、該相対寄与が動的に変化するのを可能にされる変化率を制限する制御装置、
を含む。
― 対象の皮膚領域を透過したか又はそこから反射された電磁放射を検出し、さらに、検出される電磁放射から検出データを得る検出器であって、検出データは、それぞれの波長部分を表す少なくとも2つの信号チャンネルにおける波長依存的な反射又は透過の情報を含む、検出器、及び、
― 本明細書において開示される、上記検出データから生理学的情報を抽出する装置、
を含む。
Claims (16)
- 対象を透過したか又は対象から反射された検出される電磁放射から、対象の少なくとも1つのバイタルサインを示す生理学的情報を抽出する装置であって、
― 対象の皮膚領域を透過したか又は対象の皮膚領域から反射された検出される電磁放射から得られる検出データのデータストリームを受ける入力インタフェースであり、前記検出データは、それぞれの波長部分を表す少なくとも2つの信号チャンネルにおける波長依存的な反射又は透過の情報を含む、入力インタフェースと、
― 動的に変化する前記少なくとも2つの信号チャンネルを混合して少なくとも1つの混合された信号にする信号ミキサと、
― 前記少なくとも1つの混合された信号から、少なくとも1つのバイタルサインを示す生理学的情報を得るプロセッサと、
― 前記信号ミキサを制御して、少なくとも1つの混合された信号に混合される前記少なくとも2つの信号チャンネルの相対寄与、及び/又は、該相対寄与が動的に変化するのを可能にされる変化率を制限する制御装置と、
を含む装置。 - 前記制御装置は、前記少なくとも2つの信号チャンネルのエネルギーがエネルギー閾値を下回る場合にのみ前記相対寄与及び/又はその変化率を制限するように構成される、請求項1に記載の装置。
- 前記入力インタフェースは、前記対象又は前記対象の一部の動きを示す動き信号を受けるように構成され、さらに、
前記制御装置は、前記動きが動き閾値を下回る場合にのみ前記相対寄与及び/又はその変化率を制限するように構成される、請求項1に記載の装置。 - 前記制御装置は、所定の値又は範囲に前記相対寄与及び/又は変化率を制限するように構成される、請求項1に記載の装置。
- 前記制御装置は、前記相対寄与を更新することによって前記変化率を制限するように構成される、請求項1に記載の装置。
- 前記少なくとも2つの信号チャンネルは、300nmから1000nmの波長間隔から選択される、請求項1に記載の装置。
- 前記信号ミキサは、ブラインド信号源分離を使用して、前記少なくとも1つの混合された信号をコンピュータ処理するように構成される、請求項1に記載の装置。
- 前記信号ミキサは、単一の混合された信号であって、前記少なくとも2つの信号チャンネルとの相関度が、正規化されたベクトルに等しくなるような単一の混合された信号をコンピュータ処理するように構成される、請求項1に記載の装置。
- 前記少なくとも2つの信号チャンネルは、少なくとも2つの直交色差信号であり、
前記信号ミキサは、前記少なくとも2つの直交色差信号から前記少なくとも1つの混合された信号をコンピュータ処理するように構成される、請求項1に記載の装置。 - 対象を透過したか又は対象から反射された検出される電磁放射から、対象の少なくとも1つのバイタルサインを示す生理学的情報を抽出する方法であって、
― 対象の皮膚領域を透過したか又は対象の皮膚領域から反射された検出される電磁放射から得られる検出データのデータストリームを受けるステップであり、前記検出データは、それぞれの波長部分を表す少なくとも2つの信号チャンネルにおける波長依存的な反射又は透過の情報を含む、ステップと、
― 動的に変化する前記少なくとも2つの信号チャンネルを混合して少なくとも1つの混合された信号にするステップと、
― 前記少なくとも1つの混合された信号から、少なくとも1つのバイタルサインを示す生理学的情報を得るステップと、
― 信号ミキサを制御して、少なくとも1つの混合された信号に混合される前記少なくとも2つの信号チャンネルの相対寄与、及び/又は、該相対寄与が動的に変化するのを可能にされる変化率を制限するステップと、
を含む方法。 - 対象を透過したか又は対象から反射された検出される電磁放射から、対象の少なくとも1つのバイタルサインを示す生理学的情報を抽出するシステムであって、
― 対象の皮膚領域を透過したか又は対象の皮膚領域から反射された電磁放射を検出し、さらに、検出される前記電磁放射から検出データを得る検出器であり、前記検出データは、それぞれの波長部分を表す少なくとも2つの信号チャンネルにおける波長依存的な反射又は透過の情報を含む、検出器と、
― 前記検出データから生理学的情報を抽出する請求項1に記載の装置と、
を含むシステム。 - 前記検出器は、フォトプレチスモグラフィ信号を取得するために前記対象の皮膚部分に乗せられるように構成されるプレチスモグラフィセンサ、及び/又は、時間の経過に伴う前記対象の一連の画像フレームを取得する画像処理ユニットを含み、前記画像フレームからフォトプレチスモグラフィ信号を得ることができる、請求項11に記載のシステム。
- プログラムコード手段を含むコンピュータプログラムであって、前記プログラムコード手段は、当該コンピュータプログラムがコンピュータ上で実行される場合に請求項10に記載の方法のステップを前記コンピュータに実行させる、コンピュータプログラム。
- 前記制御装置は、前記相対寄与を再帰的に更新することによって前記変化率を制限するように構成される、請求項1に記載の装置。
- 前記少なくとも2つの信号チャンネルは、赤、緑及び青色の光に対応する波長部分を表す波長間隔から選択される、請求項1に記載の装置。
- 前記信号ミキサは、主成分分析又は独立成分分析を使用して、前記少なくとも1つの混合された信号をコンピュータ処理するように構成される、請求項1に記載の装置。
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Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20200305739A1 (en) * | 2019-04-01 | 2020-10-01 | Anya L. Getman | Portable scanning device and processing system |
US10660533B2 (en) * | 2014-09-30 | 2020-05-26 | Rapsodo Pte. Ltd. | Remote heart rate monitoring based on imaging for moving subjects |
EP3204064B1 (en) | 2014-10-10 | 2020-12-02 | NxStage Medical, Inc. | Flow balancing devices, methods, and systems |
CN105455781A (zh) * | 2015-11-17 | 2016-04-06 | 努比亚技术有限公司 | 信息处理方法及电子设备 |
CN108471962B (zh) * | 2015-12-01 | 2021-04-20 | 皇家飞利浦有限公司 | 用于确定对象的生命体征信息的设备、系统和方法 |
WO2017121834A1 (en) | 2016-01-15 | 2017-07-20 | Koninklijke Philips N.V. | Device, system and method for generating a photoplethysmographic image carrying vital sign information of a subject |
US11076801B2 (en) | 2016-06-19 | 2021-08-03 | Orthospin Ltd. | User interface for strut device |
CN109328031A (zh) * | 2016-06-24 | 2019-02-12 | 皇家飞利浦有限公司 | 用于生命体征检测的系统和方法 |
US10335045B2 (en) | 2016-06-24 | 2019-07-02 | Universita Degli Studi Di Trento | Self-adaptive matrix completion for heart rate estimation from face videos under realistic conditions |
US10376221B2 (en) * | 2016-07-06 | 2019-08-13 | Biosense Webster (Israel) Ltd. | Automatic creation of multiple electroanatomic maps |
EP3484536B1 (en) | 2016-07-18 | 2022-04-27 | NxStage Medical Inc. | Flow balancing devices, methods, and systems |
KR101936784B1 (ko) * | 2016-12-12 | 2019-01-09 | 광주과학기술원 | 이미지로부터 실시간으로 혈류변화를 측정하기 위한 방법, 장치 및 컴퓨터-판독가능 저장 매체 |
US11865243B2 (en) | 2016-08-30 | 2024-01-09 | Nxstage Medical, Inc. | Parameter monitoring in medical treatment systems |
US11452456B2 (en) * | 2016-11-01 | 2022-09-27 | Koninklijke Philips N.V. | Device, system and method for determining the core body temperature of a subject |
WO2018150554A1 (ja) * | 2017-02-20 | 2018-08-23 | マクセル株式会社 | 脈波測定装置、携帯端末装置及び脈波測定方法 |
EP3375351A1 (en) | 2017-03-13 | 2018-09-19 | Koninklijke Philips N.V. | Device, system and method for measuring and processing physiological signals of a subject |
TW201903708A (zh) * | 2017-06-06 | 2019-01-16 | 國立陽明大學 | 數位減影血管攝影圖像的分析方法與系統 |
CN111052130A (zh) | 2017-08-09 | 2020-04-21 | 利兰斯坦福初级大学董事会 | 交互式生物识别触摸扫描仪 |
CN111868505B (zh) * | 2018-01-15 | 2023-08-18 | 维塔生物科技公司 | 基于电磁波发射的样本分析 |
CN110236509A (zh) * | 2018-03-07 | 2019-09-17 | 台北科技大学 | 于视频中实时分析生理特征的方法 |
CN109008998A (zh) * | 2018-05-28 | 2018-12-18 | 四川大学 | 智能脉搏信号检测系统 |
EP3581091A1 (en) * | 2018-06-12 | 2019-12-18 | Koninklijke Philips N.V. | System and method for determining at least one vital sign of a subject |
EP3581093A1 (en) * | 2018-06-13 | 2019-12-18 | Koninklijke Philips N.V. | Determining reliability of vital signs of a monitored subject |
CN109171649B (zh) * | 2018-08-30 | 2021-08-17 | 合肥工业大学 | 智能影像式生命体征探测仪 |
JP7212499B2 (ja) * | 2018-10-31 | 2023-01-25 | 株式会社日立製作所 | 生体情報検出装置及び生体情報検出方法 |
EP3698704A1 (en) * | 2019-02-20 | 2020-08-26 | Koninklijke Philips N.V. | Device, system and method for determining physiological information |
TWI690296B (zh) * | 2019-02-22 | 2020-04-11 | 黃世杰 | 局部血循狀態即時監控系統 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5853364A (en) * | 1995-08-07 | 1998-12-29 | Nellcor Puritan Bennett, Inc. | Method and apparatus for estimating physiological parameters using model-based adaptive filtering |
WO1998018256A2 (en) * | 1996-10-24 | 1998-04-30 | Philips Electronics N.V. | Noise filtering |
US20040235950A1 (en) * | 1999-05-20 | 2004-11-25 | Voorhees John J. | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes |
US8126524B2 (en) | 2003-09-12 | 2012-02-28 | Or-Nim Medical Ltd. | Method and apparatus for noninvasively monitoring parameters of a region of interest in a human body |
DE102004016435B4 (de) | 2004-03-31 | 2009-05-28 | Imedos Gmbh | Verfahren zur spektralphotometrischen Ermittlung der Sauerstoffsättigung des Blutes in optisch zugänglichen Blutgefäßen |
EP1611847A1 (en) * | 2004-06-28 | 2006-01-04 | Datex-Ohmeda, Inc. | Validating pulse oximetry signals in the potential presence of artifact |
ES2427546T3 (es) | 2005-03-16 | 2013-10-30 | Or-Nim Medical Ltd. | Mediciones no invasivas en el cuerpo de un humano |
GB0607270D0 (en) * | 2006-04-11 | 2006-05-17 | Univ Nottingham | The pulsing blood supply |
JP4573843B2 (ja) * | 2007-01-18 | 2010-11-04 | 株式会社豊田中央研究所 | 電力用半導体素子の駆動回路 |
JP5369726B2 (ja) * | 2009-02-02 | 2013-12-18 | セイコーエプソン株式会社 | 拍動検出装置、および拍動検出方法 |
KR101141002B1 (ko) * | 2009-07-28 | 2012-05-02 | 삼성전기주식회사 | 편평형 진동모터 |
DE102010006956B4 (de) * | 2010-02-02 | 2012-03-29 | Technische Universität Berlin | Verfahren und Messgerät zum Messen der Sauerstoffsättigung im Blut |
US20110251493A1 (en) * | 2010-03-22 | 2011-10-13 | Massachusetts Institute Of Technology | Method and system for measurement of physiological parameters |
KR101172971B1 (ko) * | 2010-07-09 | 2012-08-09 | 엔에이치엔(주) | 이웃 연결 서비스 시스템 및 방법 |
US9124777B2 (en) | 2011-01-05 | 2015-09-01 | Koninklijke Philips N.V. | Device and method for extracting information from characteristic signals |
CN103314583B (zh) | 2011-01-05 | 2017-05-17 | 皇家飞利浦电子股份有限公司 | 保留ppg相关信息的视频编码和解码设备及方法 |
WO2012143842A2 (en) * | 2011-04-21 | 2012-10-26 | Koninklijke Philips Electronics N.V. | Device and method for vital sign measurement of a person |
WO2012158840A1 (en) | 2011-05-17 | 2012-11-22 | Lifeflow Technologies, Inc. | Patient monitoring and surveillance tag |
JP5672144B2 (ja) * | 2011-05-20 | 2015-02-18 | 富士通株式会社 | 心拍数・呼吸数検出装置,方法およびプログラム |
TR201910353T4 (tr) | 2011-08-26 | 2019-07-22 | Koninklijke Philips Nv | Bozulma azaltmalı sinyal tespiti . |
EP2745240A2 (en) | 2011-09-29 | 2014-06-25 | Koninklijke Philips N.V. | Distortion reduced signal detection |
EP2819569B1 (en) * | 2012-02-28 | 2019-05-22 | Koninklijke Philips N.V. | Device and method for monitoring vital signs |
BR112015001773A2 (pt) * | 2012-07-30 | 2017-07-04 | Koninklijke Philips Nv | dispositivo para extrair informações fisiológicas de radiação eletromagnética emitida ou refletida por um indivíduo, método para extrair informações fisiológicas de radiação eletromagnética emitida ou refletida por um indivíduo, e programa de computador |
WO2014024104A1 (en) | 2012-08-06 | 2014-02-13 | Koninklijke Philips N.V. | Device and method for extracting physiological information |
EP2967332B1 (en) * | 2013-03-13 | 2023-05-10 | Koninklijke Philips N.V. | Apparatus and method for determining vital signs from a subject |
CN105188521A (zh) * | 2013-03-14 | 2015-12-23 | 皇家飞利浦有限公司 | 用于获得对象的生命体征信息的设备和方法 |
RU2691006C2 (ru) * | 2013-04-09 | 2019-06-07 | Конинклейке Филипс Н.В. | Приспособление и способ определения сигналов дыхания грудной клетки и брюшной полости по данным изображения |
JP6142664B2 (ja) * | 2013-05-14 | 2017-06-07 | 富士通株式会社 | 脈波検出装置、脈波検出プログラム、脈波検出方法及びコンテンツ評価システム |
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