JP6095984B2 - Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー - Google Patents

Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー Download PDF

Info

Publication number
JP6095984B2
JP6095984B2 JP2012556133A JP2012556133A JP6095984B2 JP 6095984 B2 JP6095984 B2 JP 6095984B2 JP 2012556133 A JP2012556133 A JP 2012556133A JP 2012556133 A JP2012556133 A JP 2012556133A JP 6095984 B2 JP6095984 B2 JP 6095984B2
Authority
JP
Japan
Prior art keywords
hcv
xid
cells
patients
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012556133A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013521497A5 (https=
JP2013521497A (ja
Inventor
アニョロ,ヴィンセント
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2013521497A publication Critical patent/JP2013521497A/ja
Publication of JP2013521497A5 publication Critical patent/JP2013521497A5/ja
Application granted granted Critical
Publication of JP6095984B2 publication Critical patent/JP6095984B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/686Anti-idiotype
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/328Vasculitis, i.e. inflammation of blood vessels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
JP2012556133A 2010-03-01 2011-02-28 Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー Expired - Fee Related JP6095984B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30916110P 2010-03-01 2010-03-01
US61/309,161 2010-03-01
PCT/US2011/026455 WO2011109285A2 (en) 2010-03-01 2011-02-28 Prognostic marker for cryoglobulinemic vasculitis and b cell malignancies in hcv infected patients

Publications (3)

Publication Number Publication Date
JP2013521497A JP2013521497A (ja) 2013-06-10
JP2013521497A5 JP2013521497A5 (https=) 2014-04-24
JP6095984B2 true JP6095984B2 (ja) 2017-03-15

Family

ID=44542788

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012556133A Expired - Fee Related JP6095984B2 (ja) 2010-03-01 2011-02-28 Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー

Country Status (7)

Country Link
US (3) US9719141B2 (https=)
EP (1) EP2542892A4 (https=)
JP (1) JP6095984B2 (https=)
AU (1) AU2011223906B2 (https=)
BR (1) BR112012021795A2 (https=)
CA (1) CA2791676A1 (https=)
WO (1) WO2011109285A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103184216B (zh) * 2011-12-27 2015-03-18 深圳华大基因科技有限公司 用于扩增免疫球蛋白重链cdr3编码序列的引物组合物及其用途
US11781112B2 (en) 2016-03-06 2023-10-10 Kareem Thomas Robinson Method of generating antigen-specific immunological memory in a subject that rejects classical vaccines
RU2642626C1 (ru) * 2016-11-03 2018-01-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ прогнозирования развития криоглобулинемического васкулита у больных хроническим гепатитом с
US11026625B2 (en) 2017-08-08 2021-06-08 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20020049A1 (it) 2002-01-30 2003-07-30 Biostrands S R L Frammenti fab di anticorpi monoclonali umani diretti contro la glicoproteina e2 di hcv e dotati di potere neutralizzante in vitro.
US8178303B2 (en) 2003-12-04 2012-05-15 Wake Forest University Health Sciences Increasing the speed of cryoglobulin precipitation
EP1801116A1 (en) 2005-12-21 2007-06-27 F. Hoffmann-La Roche Ag HCV replicon shuttle vectors

Also Published As

Publication number Publication date
WO2011109285A2 (en) 2011-09-09
BR112012021795A2 (pt) 2016-05-17
US9719141B2 (en) 2017-08-01
EP2542892A2 (en) 2013-01-09
US20160083801A1 (en) 2016-03-24
CA2791676A1 (en) 2011-09-09
WO2011109285A3 (en) 2012-01-19
EP2542892A4 (en) 2013-11-27
US20130052206A1 (en) 2013-02-28
AU2011223906A1 (en) 2012-09-13
CN102859360A (zh) 2013-01-02
JP2013521497A (ja) 2013-06-10
US20180002763A1 (en) 2018-01-04
AU2011223906B2 (en) 2015-06-25

Similar Documents

Publication Publication Date Title
Crouchet et al. A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery
Persico et al. Hepatitis C virus carriers with persistently normal ALT levels: biological peculiarities and update of the natural history of liver disease at 10 years
CN104160039B (zh) 川崎病的生物标志物
US20180002763A1 (en) Prognostic Marker For Cryoglobulinemic Vasculitis And B Cell Malignancies In HCV Infected Patients
Ramesh et al. The role of myositis-specific autoantibodies in the dermatomyositis spectrum
WO2025031331A1 (zh) Plekhh2在肺动脉高压诊断和治疗方面的应用
WO2014185631A1 (ko) Tgfbi를 이용한 패혈증 진단용 조성물 및 이를 이용한 패혈증 예방 또는 치료용 약학적 조성물과 이의 스크리닝 방법
WO2017175228A1 (en) Infiltrating immune cell proportions predict anti-tnf response in colon biopsies
Knight et al. Detection of WA B cells in hepatitis C virus infection: a potential prognostic marker for cryoglobulinemic vasculitis and B cell malignancies
De Almeida et al. Autoimmune thrombocytopenia related to chronic hepatitis C virus infection
Xian et al. Potential involvement of M1 macrophage and VLA4/VCAM-1 pathway in the valvular damage due to rheumatic heart disease
Gerçeker et al. Steroid resistance/dependence might be an alarming feature for cytomegalovirus infection among ulcerative colitis patients with increased disease activity
US20220128578A1 (en) Biomarkers of progressive multifocal leukoencephalopathy
JP2013021932A (ja) 関節リウマチに対する抗il−6受容体抗体療法の有効性の予測方法
JP2013521497A5 (https=)
CN118879851A (zh) 肺动脉高压相关的plekhh2基因突变及其应用
CN102859360B (zh) Hcv感染患者中的冷球蛋白血症性血管炎和b细胞恶性肿瘤的预测标志物
EP1342727A1 (en) Antibody against norwalk virus and method of detecting virus by using the antibody
JP2024005979A (ja) 肉芽腫または肉芽腫を伴う疾患を処置および/または予防するための組成物および対象が肉芽腫を有するか否かを判定するための方法およびキット
JP2011211970A (ja) インターフェロンに対する感受性又は応答性を予測する方法、キット及びマーカー遺伝子
WO2005019268A1 (ja) 新規癌抗原に対する抗体
CN120193078A (zh) 预测病毒相关肝癌免疫治疗疗效的标志物及其应用
Hammad et al. T-cytotoxic Expression of Leukocyte-Associated Immunoglobulin-like Receptor-1 (LAIR-1) in post-HCV Hepatocellular Carcinoma
Caviglia et al. Long-Term Hepatocellular Carcinoma Development and Predictive Ability of Non-Invasive Scoring Systems in Patients with HCV-Related Cirrhosis Treated with Direct-Acting Antivirals. Cancers. 2022; 14 (3): 828.[PubMed ID: 35159094].[PubMed Central ID: PMC8834182]
KR101968962B1 (ko) 비만 저항성 진단용 조성물

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140228

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140228

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150407

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150703

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150806

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150907

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20151124

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160324

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20160602

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160726

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160915

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170117

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170215

R150 Certificate of patent or registration of utility model

Ref document number: 6095984

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees