JP6095984B2 - Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー - Google Patents
Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー Download PDFInfo
- Publication number
- JP6095984B2 JP6095984B2 JP2012556133A JP2012556133A JP6095984B2 JP 6095984 B2 JP6095984 B2 JP 6095984B2 JP 2012556133 A JP2012556133 A JP 2012556133A JP 2012556133 A JP2012556133 A JP 2012556133A JP 6095984 B2 JP6095984 B2 JP 6095984B2
- Authority
- JP
- Japan
- Prior art keywords
- hcv
- xid
- cells
- patients
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/686—Anti-idiotype
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/328—Vasculitis, i.e. inflammation of blood vessels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30916110P | 2010-03-01 | 2010-03-01 | |
| US61/309,161 | 2010-03-01 | ||
| PCT/US2011/026455 WO2011109285A2 (en) | 2010-03-01 | 2011-02-28 | Prognostic marker for cryoglobulinemic vasculitis and b cell malignancies in hcv infected patients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013521497A JP2013521497A (ja) | 2013-06-10 |
| JP2013521497A5 JP2013521497A5 (https=) | 2014-04-24 |
| JP6095984B2 true JP6095984B2 (ja) | 2017-03-15 |
Family
ID=44542788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556133A Expired - Fee Related JP6095984B2 (ja) | 2010-03-01 | 2011-02-28 | Hcv感染患者のクリオグロブリン血症性血管炎およびb細胞悪性腫瘍のための予後マーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9719141B2 (https=) |
| EP (1) | EP2542892A4 (https=) |
| JP (1) | JP6095984B2 (https=) |
| AU (1) | AU2011223906B2 (https=) |
| BR (1) | BR112012021795A2 (https=) |
| CA (1) | CA2791676A1 (https=) |
| WO (1) | WO2011109285A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103184216B (zh) * | 2011-12-27 | 2015-03-18 | 深圳华大基因科技有限公司 | 用于扩增免疫球蛋白重链cdr3编码序列的引物组合物及其用途 |
| US11781112B2 (en) | 2016-03-06 | 2023-10-10 | Kareem Thomas Robinson | Method of generating antigen-specific immunological memory in a subject that rejects classical vaccines |
| RU2642626C1 (ru) * | 2016-11-03 | 2018-01-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ прогнозирования развития криоглобулинемического васкулита у больных хроническим гепатитом с |
| US11026625B2 (en) | 2017-08-08 | 2021-06-08 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20020049A1 (it) | 2002-01-30 | 2003-07-30 | Biostrands S R L | Frammenti fab di anticorpi monoclonali umani diretti contro la glicoproteina e2 di hcv e dotati di potere neutralizzante in vitro. |
| US8178303B2 (en) | 2003-12-04 | 2012-05-15 | Wake Forest University Health Sciences | Increasing the speed of cryoglobulin precipitation |
| EP1801116A1 (en) | 2005-12-21 | 2007-06-27 | F. Hoffmann-La Roche Ag | HCV replicon shuttle vectors |
-
2011
- 2011-02-28 WO PCT/US2011/026455 patent/WO2011109285A2/en not_active Ceased
- 2011-02-28 AU AU2011223906A patent/AU2011223906B2/en not_active Ceased
- 2011-02-28 EP EP11751140.2A patent/EP2542892A4/en not_active Withdrawn
- 2011-02-28 BR BR112012021795A patent/BR112012021795A2/pt not_active IP Right Cessation
- 2011-02-28 JP JP2012556133A patent/JP6095984B2/ja not_active Expired - Fee Related
- 2011-02-28 US US13/581,759 patent/US9719141B2/en not_active Expired - Fee Related
- 2011-02-28 CA CA2791676A patent/CA2791676A1/en not_active Abandoned
-
2015
- 2015-09-23 US US14/863,220 patent/US20160083801A1/en not_active Abandoned
-
2017
- 2017-09-11 US US15/701,379 patent/US20180002763A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011109285A2 (en) | 2011-09-09 |
| BR112012021795A2 (pt) | 2016-05-17 |
| US9719141B2 (en) | 2017-08-01 |
| EP2542892A2 (en) | 2013-01-09 |
| US20160083801A1 (en) | 2016-03-24 |
| CA2791676A1 (en) | 2011-09-09 |
| WO2011109285A3 (en) | 2012-01-19 |
| EP2542892A4 (en) | 2013-11-27 |
| US20130052206A1 (en) | 2013-02-28 |
| AU2011223906A1 (en) | 2012-09-13 |
| CN102859360A (zh) | 2013-01-02 |
| JP2013521497A (ja) | 2013-06-10 |
| US20180002763A1 (en) | 2018-01-04 |
| AU2011223906B2 (en) | 2015-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Crouchet et al. | A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery | |
| Persico et al. | Hepatitis C virus carriers with persistently normal ALT levels: biological peculiarities and update of the natural history of liver disease at 10 years | |
| CN104160039B (zh) | 川崎病的生物标志物 | |
| US20180002763A1 (en) | Prognostic Marker For Cryoglobulinemic Vasculitis And B Cell Malignancies In HCV Infected Patients | |
| Ramesh et al. | The role of myositis-specific autoantibodies in the dermatomyositis spectrum | |
| WO2025031331A1 (zh) | Plekhh2在肺动脉高压诊断和治疗方面的应用 | |
| WO2014185631A1 (ko) | Tgfbi를 이용한 패혈증 진단용 조성물 및 이를 이용한 패혈증 예방 또는 치료용 약학적 조성물과 이의 스크리닝 방법 | |
| WO2017175228A1 (en) | Infiltrating immune cell proportions predict anti-tnf response in colon biopsies | |
| Knight et al. | Detection of WA B cells in hepatitis C virus infection: a potential prognostic marker for cryoglobulinemic vasculitis and B cell malignancies | |
| De Almeida et al. | Autoimmune thrombocytopenia related to chronic hepatitis C virus infection | |
| Xian et al. | Potential involvement of M1 macrophage and VLA4/VCAM-1 pathway in the valvular damage due to rheumatic heart disease | |
| Gerçeker et al. | Steroid resistance/dependence might be an alarming feature for cytomegalovirus infection among ulcerative colitis patients with increased disease activity | |
| US20220128578A1 (en) | Biomarkers of progressive multifocal leukoencephalopathy | |
| JP2013021932A (ja) | 関節リウマチに対する抗il−6受容体抗体療法の有効性の予測方法 | |
| JP2013521497A5 (https=) | ||
| CN118879851A (zh) | 肺动脉高压相关的plekhh2基因突变及其应用 | |
| CN102859360B (zh) | Hcv感染患者中的冷球蛋白血症性血管炎和b细胞恶性肿瘤的预测标志物 | |
| EP1342727A1 (en) | Antibody against norwalk virus and method of detecting virus by using the antibody | |
| JP2024005979A (ja) | 肉芽腫または肉芽腫を伴う疾患を処置および/または予防するための組成物および対象が肉芽腫を有するか否かを判定するための方法およびキット | |
| JP2011211970A (ja) | インターフェロンに対する感受性又は応答性を予測する方法、キット及びマーカー遺伝子 | |
| WO2005019268A1 (ja) | 新規癌抗原に対する抗体 | |
| CN120193078A (zh) | 预测病毒相关肝癌免疫治疗疗效的标志物及其应用 | |
| Hammad et al. | T-cytotoxic Expression of Leukocyte-Associated Immunoglobulin-like Receptor-1 (LAIR-1) in post-HCV Hepatocellular Carcinoma | |
| Caviglia et al. | Long-Term Hepatocellular Carcinoma Development and Predictive Ability of Non-Invasive Scoring Systems in Patients with HCV-Related Cirrhosis Treated with Direct-Acting Antivirals. Cancers. 2022; 14 (3): 828.[PubMed ID: 35159094].[PubMed Central ID: PMC8834182] | |
| KR101968962B1 (ko) | 비만 저항성 진단용 조성물 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140228 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20140228 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150407 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20150703 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20150806 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150907 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20151124 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160324 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20160602 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160726 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160915 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170117 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170215 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6095984 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| LAPS | Cancellation because of no payment of annual fees |