JP2013521497A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013521497A5 JP2013521497A5 JP2012556133A JP2012556133A JP2013521497A5 JP 2013521497 A5 JP2013521497 A5 JP 2013521497A5 JP 2012556133 A JP2012556133 A JP 2012556133A JP 2012556133 A JP2012556133 A JP 2012556133A JP 2013521497 A5 JP2013521497 A5 JP 2013521497A5
- Authority
- JP
- Japan
- Prior art keywords
- xid
- hcv
- subject
- specimen
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 25
- 210000003719 b-lymphocyte Anatomy 0.000 claims 20
- 241000711549 Hepacivirus C Species 0.000 claims 18
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 230000036210 malignancy Effects 0.000 claims 10
- 206010047115 Vasculitis Diseases 0.000 claims 9
- 201000003278 cryoglobulinemia Diseases 0.000 claims 9
- 150000007523 nucleic acids Chemical group 0.000 claims 9
- 108060003951 Immunoglobulin Proteins 0.000 claims 7
- 102000018358 immunoglobulin Human genes 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 208000015181 infectious disease Diseases 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 210000004602 germ cell Anatomy 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 2
- 108010004729 Phycoerythrin Proteins 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 238000013399 early diagnosis Methods 0.000 claims 2
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 101100341519 Homo sapiens ITGAX gene Proteins 0.000 claims 1
- 102100022297 Integrin alpha-X Human genes 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 208000010710 hepatitis C virus infection Diseases 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30916110P | 2010-03-01 | 2010-03-01 | |
| US61/309,161 | 2010-03-01 | ||
| PCT/US2011/026455 WO2011109285A2 (en) | 2010-03-01 | 2011-02-28 | Prognostic marker for cryoglobulinemic vasculitis and b cell malignancies in hcv infected patients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013521497A JP2013521497A (ja) | 2013-06-10 |
| JP2013521497A5 true JP2013521497A5 (https=) | 2014-04-24 |
| JP6095984B2 JP6095984B2 (ja) | 2017-03-15 |
Family
ID=44542788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556133A Expired - Fee Related JP6095984B2 (ja) | 2010-03-01 | 2011-02-28 | Ｈｃｖ感染患者のクリオグロブリン血症性血管炎およびｂ細胞悪性腫瘍のための予後マーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9719141B2 (https=) |
| EP (1) | EP2542892A4 (https=) |
| JP (1) | JP6095984B2 (https=) |
| AU (1) | AU2011223906B2 (https=) |
| BR (1) | BR112012021795A2 (https=) |
| CA (1) | CA2791676A1 (https=) |
| WO (1) | WO2011109285A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103184216B (zh) * | 2011-12-27 | 2015-03-18 | 深圳华大基因科技有限公司 | 用于扩增免疫球蛋白重链cdr3编码序列的引物组合物及其用途 |
| US11781112B2 (en) | 2016-03-06 | 2023-10-10 | Kareem Thomas Robinson | Method of generating antigen-specific immunological memory in a subject that rejects classical vaccines |
| RU2642626C1 (ru) * | 2016-11-03 | 2018-01-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ прогнозирования развития криоглобулинемического васкулита у больных хроническим гепатитом с |
| US11026625B2 (en) | 2017-08-08 | 2021-06-08 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20020049A1 (it) | 2002-01-30 | 2003-07-30 | Biostrands S R L | Frammenti fab di anticorpi monoclonali umani diretti contro la glicoproteina e2 di hcv e dotati di potere neutralizzante in vitro. |
| US8178303B2 (en) | 2003-12-04 | 2012-05-15 | Wake Forest University Health Sciences | Increasing the speed of cryoglobulin precipitation |
| EP1801116A1 (en) | 2005-12-21 | 2007-06-27 | F. Hoffmann-La Roche Ag | HCV replicon shuttle vectors |
-
2011
- 2011-02-28 WO PCT/US2011/026455 patent/WO2011109285A2/en not_active Ceased
- 2011-02-28 AU AU2011223906A patent/AU2011223906B2/en not_active Ceased
- 2011-02-28 EP EP11751140.2A patent/EP2542892A4/en not_active Withdrawn
- 2011-02-28 BR BR112012021795A patent/BR112012021795A2/pt not_active IP Right Cessation
- 2011-02-28 JP JP2012556133A patent/JP6095984B2/ja not_active Expired - Fee Related
- 2011-02-28 US US13/581,759 patent/US9719141B2/en not_active Expired - Fee Related
- 2011-02-28 CA CA2791676A patent/CA2791676A1/en not_active Abandoned
-
2015
- 2015-09-23 US US14/863,220 patent/US20160083801A1/en not_active Abandoned
-
2017
- 2017-09-11 US US15/701,379 patent/US20180002763A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6092655B2 (ja) | テスト体液サンプルの分類方法 | |
| CN107541563B (zh) | 一种用于早期诊断、预测脓毒血症并发急性肾损伤的分子标记物、试剂盒及应用 | |
| McArdle et al. | Discovery proteomics for COVID-19: where we are now | |
| JP2019528455A (ja) | 新規な肝硬変または肝線維症のマーカー | |
| CN109337909B (zh) | 一种检测肝癌耐药细胞株的核酸适体及其应用 | |
| WO2009130176A9 (en) | Antiviral therapy | |
| CN107267649B (zh) | Stradb在哮喘早期诊断中的应用 | |
| RU2013113314A (ru) | Способы выявления антител против не4 и способы диагностики и/или прогнозирования состояний, ассоциированных с экспрессирующими не4 клетками | |
| Young et al. | A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease | |
| JP2013521497A5 (https=) | ||
| CN107488737A (zh) | 一种检测外周血tcr可变区编码基因的液体活检试剂盒及其应用 | |
| CN107164529A (zh) | 一种与哮喘发生发展相关的基因的应用 | |
| CN108796074B (zh) | 检测环状RNA circRNF13的试剂在制备肿瘤辅助诊断制剂上的应用及试剂盒 | |
| CN108660215B (zh) | 检测circMAN1A2和circRNF13试剂的应用及试剂盒 | |
| CN107164536A (zh) | Mrnip基因在重度抑郁症诊断中的应用 | |
| CN120485376B (zh) | 一种用于辅助诊断肠癌的eRNA分子标记物及其应用 | |
| JP6095984B2 (ja) | Ｈｃｖ感染患者のクリオグロブリン血症性血管炎およびｂ細胞悪性腫瘍のための予後マーカー | |
| CN105648075A (zh) | 一种肝癌诊断组合及含有该组合的试剂盒 | |
| CN118879851A (zh) | 肺动脉高压相关的plekhh2基因突变及其应用 | |
| US20230133776A1 (en) | Methods for diagnosing cancer | |
| CN102021169A (zh) | 一种血清/血浆miRNA组合物及其应用 | |
| CN108676880B (zh) | 一种人血清afp阴性肝细胞癌检测试剂盒 | |
| KR101351234B1 (ko) | 간암 진단용 마커로서 Ｇａｎｋｙｒｉｎ의 용도 | |
| CN112877440B (zh) | 生物标志物在预测肝癌复发中的应用 | |
| CN104630379A (zh) | 非小细胞型肺癌标志物fam107a及其应用 |