JP6083860B2 - Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 - Google Patents

Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 Download PDF

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JP6083860B2
JP6083860B2 JP2012511052A JP2012511052A JP6083860B2 JP 6083860 B2 JP6083860 B2 JP 6083860B2 JP 2012511052 A JP2012511052 A JP 2012511052A JP 2012511052 A JP2012511052 A JP 2012511052A JP 6083860 B2 JP6083860 B2 JP 6083860B2
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odc
patient
agent
ornithine decarboxylase
genotype
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JP2012526852A (ja
JP2012526852A5 (cg-RX-API-DMAC10.html
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ガーナー，ユージーン
ゼル，ジェイソン
マクラレン，クリスティン
メイスケンス，フランク
アントン−カルバー，ホダ
トンプソン，パトリシア，エー．
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University of Arizona
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
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    • A61K31/415—1,2-Diazoles
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Animal Behavior & Ethology (AREA)
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  • Urology & Nephrology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012511052A 2009-05-14 2010-05-14 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療 Expired - Fee Related JP6083860B2 (ja)

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US21621609P 2009-05-14 2009-05-14
US61/216,216 2009-05-14
US21768209P 2009-06-03 2009-06-03
US21767909P 2009-06-03 2009-06-03
US61/217,679 2009-06-03
US61/217,682 2009-06-03
PCT/US2010/034974 WO2010132817A1 (en) 2009-05-14 2010-05-14 Carcinoma diagnosis and treatments, based on odc1 genotype

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JP2015213116A Division JP2016074672A (ja) 2009-05-14 2015-10-29 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療

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JP2012526852A JP2012526852A (ja) 2012-11-01
JP2012526852A5 JP2012526852A5 (cg-RX-API-DMAC10.html) 2013-06-27
JP6083860B2 true JP6083860B2 (ja) 2017-02-22

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JP2012511052A Expired - Fee Related JP6083860B2 (ja) 2009-05-14 2010-05-14 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療
JP2015213116A Pending JP2016074672A (ja) 2009-05-14 2015-10-29 Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療

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US (4) US8329636B2 (cg-RX-API-DMAC10.html)
EP (1) EP2430452B1 (cg-RX-API-DMAC10.html)
JP (2) JP6083860B2 (cg-RX-API-DMAC10.html)
CN (1) CN102483415B (cg-RX-API-DMAC10.html)
AU (1) AU2010248803B2 (cg-RX-API-DMAC10.html)
CA (1) CA2761946A1 (cg-RX-API-DMAC10.html)
DK (1) DK2430452T3 (cg-RX-API-DMAC10.html)
ES (1) ES2507145T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20140887T1 (cg-RX-API-DMAC10.html)
IL (1) IL216369B (cg-RX-API-DMAC10.html)
PL (1) PL2430452T3 (cg-RX-API-DMAC10.html)
PT (1) PT2430452E (cg-RX-API-DMAC10.html)
SI (1) SI2430452T1 (cg-RX-API-DMAC10.html)
SM (1) SMT201400177B (cg-RX-API-DMAC10.html)
WO (1) WO2010132817A1 (cg-RX-API-DMAC10.html)

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DK2430452T3 (da) 2009-05-14 2014-10-06 Univ Arizona State Carcinom-diagnose og behandlinger, baseret på odc1-genotype
EP2568978B1 (en) * 2010-05-14 2019-04-24 Arizona Board of Regents on Behalf of University of Arizona Cancer prevention and treatment based on dietary polyamine content
US20120172244A1 (en) 2010-12-20 2012-07-05 Steven Buechler Biomarkers and uses thereof in prognosis and treatment strategies for right-side colon cancer disease and left-side colon cancer disease
EP2655663A4 (en) * 2010-12-20 2015-01-28 Univ Notre Dame Du Lac BIOMARKERS AND THEIR USE FOR PROGNOSIS AND TREATMENT STRATEGIES FOR RIGHT-SIDED AND LEFT-SIDE COLON CARCINOMA
EP2912193B1 (en) 2012-10-29 2018-08-29 Arizona Board of Regents on Behalf of University of Arizona Predictive markers for polyamine inhibitor cancer therapies
CA2952771A1 (en) * 2014-06-18 2015-12-23 Arizona Board Of Regents On Behalf Of The University Of Arizona Carcinoma diagnosis and treatment based on odc1 genotype
JP2018507910A (ja) * 2015-02-12 2018-03-22 ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ジ・ユニバーシティ・オブ・アリゾナ 神経芽細胞腫を治療する方法
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JP2018536707A (ja) 2015-10-30 2018-12-13 キャンサー プリベンション ファーマシューティカルズ，インコーポレイテッド エフロルニチンとスリンダクの固定用量複合製剤
JP6963271B2 (ja) * 2017-01-20 2021-11-05 国立大学法人東海国立大学機構 イヌの遺伝性消化管腫瘍症の遺伝子診断法
TWI917322B (zh) 2019-05-17 2026-03-11 美商癌症預防製藥股份有限公司 治療家族性腺瘤性瘜肉症之方法

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WO2010132817A1 (en) 2010-11-18
US9121852B2 (en) 2015-09-01
IL216369B (en) 2018-07-31
US20160213634A1 (en) 2016-07-28
EP2430452B1 (en) 2014-06-25
EP2430452A1 (en) 2012-03-21
CA2761946A1 (en) 2010-11-18
US20190038584A1 (en) 2019-02-07
SI2430452T1 (sl) 2014-11-28
PT2430452E (pt) 2014-09-30
ES2507145T3 (es) 2014-10-14
IL216369A0 (en) 2012-01-31
HRP20140887T1 (hr) 2014-11-21
US20100317708A1 (en) 2010-12-16
PL2430452T3 (pl) 2014-12-31
DK2430452T3 (da) 2014-10-06
AU2010248803A1 (en) 2011-12-01
US8329636B2 (en) 2012-12-11
US9937141B2 (en) 2018-04-10
US20130164751A1 (en) 2013-06-27
CN102483415B (zh) 2015-09-09
CN102483415A (zh) 2012-05-30
JP2016074672A (ja) 2016-05-12
SMT201400177B (it) 2015-01-15
EP2430452A4 (en) 2013-03-06
HK1171082A1 (en) 2013-03-15
AU2010248803B2 (en) 2014-05-29
JP2012526852A (ja) 2012-11-01

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