JP6059718B2 - 生物試料成分の処理 - Google Patents

生物試料成分の処理 Download PDF

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Publication number
JP6059718B2
JP6059718B2 JP2014515330A JP2014515330A JP6059718B2 JP 6059718 B2 JP6059718 B2 JP 6059718B2 JP 2014515330 A JP2014515330 A JP 2014515330A JP 2014515330 A JP2014515330 A JP 2014515330A JP 6059718 B2 JP6059718 B2 JP 6059718B2
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JP
Japan
Prior art keywords
compartment
filter element
magnetic field
sample
processing apparatus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2014515330A
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English (en)
Japanese (ja)
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JP2014517318A (ja
Inventor
ミハイル ミハイロヴィチ オヴスヤンコ
ミハイル ミハイロヴィチ オヴスヤンコ
へメルト フレーク ファン
ヘメルト フレーク ファン
メノー ウィレム ヨセ プリンス
メノー ウィレム ヨセ プリンス
デ ストルペ アニア ファン
デ ストルペ アニア ファン
フリードル ラインホルト ウィンベルガー
フリードル ラインホルト ウィンベルガー
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Koninklijke Philips NV
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Koninklijke Philips NV
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Publication of JP2014517318A publication Critical patent/JP2014517318A/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/30—Combinations with other devices, not otherwise provided for
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2014515330A 2011-06-15 2012-06-14 生物試料成分の処理 Expired - Fee Related JP6059718B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11169981.5 2011-06-15
EP11169981 2011-06-15
PCT/IB2012/053005 WO2012172503A1 (en) 2011-06-15 2012-06-14 Processing of biological sample components

Publications (2)

Publication Number Publication Date
JP2014517318A JP2014517318A (ja) 2014-07-17
JP6059718B2 true JP6059718B2 (ja) 2017-01-11

Family

ID=46458571

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014515330A Expired - Fee Related JP6059718B2 (ja) 2011-06-15 2012-06-14 生物試料成分の処理

Country Status (5)

Country Link
US (1) US20140295420A1 (de)
EP (1) EP2720798B1 (de)
JP (1) JP6059718B2 (de)
CN (1) CN103608116B (de)
WO (1) WO2012172503A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6727062B2 (ja) * 2015-09-30 2020-07-22 シスメックス株式会社 検出方法および検出装置
US11268056B2 (en) * 2015-12-29 2022-03-08 Life Technologies Corporation Flexible bioprocessing container with partial dividing partition
US10161908B2 (en) * 2016-03-24 2018-12-25 Infineon Technologies Ag Apparatus for determining a characteristic of a fluid having a device configured to measure a hydrodynamic pressure of the fluid
CN111226116B (zh) * 2017-06-19 2024-05-03 微球实验公司 组合式分离

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100867A (en) * 1991-02-06 1995-12-08 Igen Inc Method and device for improved luminescence testing
ATE184320T1 (de) * 1991-07-10 1999-09-15 Igen Int Inc Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis
US6890426B2 (en) * 1996-06-07 2005-05-10 Immunivest Corporation Magnetic separation apparatus and methods
ATE404269T1 (de) * 1998-11-30 2008-08-15 Immunivest Corp Verfahren und vorrichtung zur magnetischen trennung
US8084270B2 (en) * 2006-01-25 2011-12-27 Koninklijke Philips Electronics N.V. Device for analyzing fluids
EP1936350A1 (de) * 2006-12-19 2008-06-25 Koninklijke Philips Electronics N.V. Verfahren zur quantitativen Messung von Agglutinationsparametern
US8057889B2 (en) * 2007-05-21 2011-11-15 Corning Incorporated Method for producing anisoptropic bulk materials
US20100300978A1 (en) * 2007-09-19 2010-12-02 Agency For Science, Technology And Research Device, system and method for washing and isolating magnetic particles in a continous fluid flow
WO2009060357A1 (en) * 2007-11-05 2009-05-14 Koninklijke Philips Electronics N. V. Biosensor cartridge
US20100291710A1 (en) * 2008-01-28 2010-11-18 Koninklijke Philips Electronics N.V. Biosensor system for external actuation of magnetic particles in a biosensor cartridge
JP5532196B2 (ja) * 2008-08-12 2014-06-25 独立行政法人産業技術総合研究所 高勾配磁気分離用フィルター
RU2011121883A (ru) * 2008-10-31 2012-12-10 Конинклейке Филипс Электроникс Н.В. Биосенсор с многокамерным контейнером
WO2010109392A1 (en) * 2009-03-23 2010-09-30 Koninklijke Philips Electronics N.V. Manipulation of magnetic particles in a biological sample
WO2010121315A1 (en) * 2009-04-22 2010-10-28 Clinical Genomics Pty. Ltd. Method and apparatus for isolating a target bioentity from a biological sample

Also Published As

Publication number Publication date
CN103608116A (zh) 2014-02-26
US20140295420A1 (en) 2014-10-02
JP2014517318A (ja) 2014-07-17
EP2720798A1 (de) 2014-04-23
EP2720798B1 (de) 2020-01-01
WO2012172503A1 (en) 2012-12-20
CN103608116B (zh) 2017-05-24

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