JP6054371B2 - 病原性疾患における細菌mamポリペプチドの調節 - Google Patents
病原性疾患における細菌mamポリペプチドの調節 Download PDFInfo
- Publication number
- JP6054371B2 JP6054371B2 JP2014503699A JP2014503699A JP6054371B2 JP 6054371 B2 JP6054371 B2 JP 6054371B2 JP 2014503699 A JP2014503699 A JP 2014503699A JP 2014503699 A JP2014503699 A JP 2014503699A JP 6054371 B2 JP6054371 B2 JP 6054371B2
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- Prior art keywords
- mam7
- mam
- infection
- cells
- pharmaceutical composition
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472440P | 2011-04-06 | 2011-04-06 | |
| US61/472,440 | 2011-04-06 | ||
| PCT/US2012/031552 WO2012138570A2 (en) | 2011-04-06 | 2012-03-30 | Modulating bacterial mam polypeptides in pathogenic disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014512361A JP2014512361A (ja) | 2014-05-22 |
| JP2014512361A5 JP2014512361A5 (enExample) | 2015-05-21 |
| JP6054371B2 true JP6054371B2 (ja) | 2016-12-27 |
Family
ID=46969760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014503699A Expired - Fee Related JP6054371B2 (ja) | 2011-04-06 | 2012-03-30 | 病原性疾患における細菌mamポリペプチドの調節 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9140698B2 (enExample) |
| EP (1) | EP2693887B1 (enExample) |
| JP (1) | JP6054371B2 (enExample) |
| AU (1) | AU2012240395B2 (enExample) |
| CA (1) | CA2832443C (enExample) |
| WO (1) | WO2012138570A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9901616B2 (en) | 2011-08-31 | 2018-02-27 | University Of Georgia Research Foundation, Inc. | Apoptosis-targeting nanoparticles |
| US10416167B2 (en) | 2012-02-17 | 2019-09-17 | University Of Georgia Research Foundation, Inc. | Nanoparticles for mitochondrial trafficking of agents |
| EP2833911A4 (en) | 2012-04-06 | 2016-07-13 | Univ Cornell | SUB-VACCINE VACCINATING PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES |
| US9815871B2 (en) | 2013-04-23 | 2017-11-14 | President And Fellows Of Harvard College | Genetic reprogramming of bacterial biofilms |
| EP3039733B1 (en) * | 2013-08-29 | 2018-11-21 | Northeastern University | Matrix-enhanced electrochemical detector for pathogenic bacteria |
| US10398663B2 (en) | 2014-03-14 | 2019-09-03 | University Of Georgia Research Foundation, Inc. | Mitochondrial delivery of 3-bromopyruvate |
| JP6916524B2 (ja) | 2015-04-06 | 2021-08-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
| US11098133B2 (en) | 2016-05-19 | 2021-08-24 | President And Fellows Of Harvard College | Methods of making gels and films using curli nanofibers |
| CA3214423A1 (en) * | 2017-02-17 | 2018-08-23 | The University Of British Columbia | Probiotic compositions and uses thereof |
| EP3720458A4 (en) | 2017-12-05 | 2021-12-08 | BioPlx, Inc. | METHODS AND COMPOSITIONS FOR PREVENTING MICROBIAL INFECTION |
| GB202003062D0 (en) | 2020-03-03 | 2020-04-15 | Univ Sheffield | Antimicrobial target |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| CN111848734B (zh) * | 2020-06-17 | 2022-04-05 | 自然资源部第三海洋研究所 | 一种具有荧光特性的铁载体pvd、制备方法及其用途 |
| CN112007143B (zh) * | 2020-08-19 | 2023-09-22 | 中山大学 | 重组副溶血弧菌鞭毛蛋白在提高鱼类免疫力中的应用 |
| WO2024059139A2 (en) * | 2022-09-13 | 2024-03-21 | University Of Cincinnati | Engineered probiotics expressing anti-inflammatory molecules |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| DE69126607T2 (de) | 1990-01-23 | 1998-01-15 | Tanox Biosystems, Inc., Houston, Tex. | Extrazelluläre teilstücke humaner ige-immunoglobulin-ankerpeptide und dafür spezifische antikörper |
| US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
| AU1570292A (en) | 1991-02-07 | 1992-09-07 | Board Of Trustees Of The University Of Illinois, The | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| US5475085A (en) | 1991-02-07 | 1995-12-12 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| US5446128A (en) | 1993-06-18 | 1995-08-29 | The Board Of Trustees Of The University Of Illinois | Alpha-helix mimetics and methods relating thereto |
| US5840833A (en) | 1995-10-27 | 1998-11-24 | Molecumetics, Ltd | Alpha-helix mimetics and methods relating thereto |
| US5929237A (en) | 1995-10-27 | 1999-07-27 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| US6444444B1 (en) * | 1996-07-10 | 2002-09-03 | Aventis Pasteur Limited | Genes encoding mycobacterial proteins associated with cell binding and cell entry and uses thereof |
| US6284255B1 (en) | 1996-08-29 | 2001-09-04 | Genesis Research & Development Corporation Limited | Compounds and methods for treatment and diagnosis of mycobacterial infections |
| US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| US7666400B2 (en) | 2005-04-06 | 2010-02-23 | Ibc Pharmaceuticals, Inc. | PEGylation by the dock and lock (DNL) technique |
| US7223558B2 (en) * | 2001-07-11 | 2007-05-29 | Bristol-Myers Squibb Company | Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof |
| US20030138490A1 (en) | 2001-09-08 | 2003-07-24 | Zhibing Hu | Synthesis and uses of polymer gel nanoparticle networks |
| US7610156B2 (en) | 2003-03-31 | 2009-10-27 | Xencor, Inc. | Methods for rational pegylation of proteins |
| WO2004089421A2 (en) | 2003-03-31 | 2004-10-21 | Xencor, Inc | Methods for rational pegylation of proteins |
| JP2007530034A (ja) * | 2004-03-23 | 2007-11-01 | エヌ.ブイ.・ヌートリシア | 新規のマンノース特異的アドヘシンとその使用 |
| GB0423126D0 (en) * | 2004-10-18 | 2004-11-17 | Ares Trading Sa | Protein |
| US20090048160A1 (en) * | 2007-08-17 | 2009-02-19 | Bannerman Douglas D | Antimicrobial activity of bovine bactericidal/permeability-increasing protein (BPI)-derived peptides against Gram-negative bacterial mastitis isolates |
| US8110656B2 (en) * | 2008-07-22 | 2012-02-07 | Board Of Trustees Of Michigan State University | Compositions and methods of a phosphatidic acid binding protein |
-
2012
- 2012-03-30 US US14/009,724 patent/US9140698B2/en not_active Expired - Fee Related
- 2012-03-30 AU AU2012240395A patent/AU2012240395B2/en not_active Ceased
- 2012-03-30 EP EP12767481.0A patent/EP2693887B1/en not_active Not-in-force
- 2012-03-30 JP JP2014503699A patent/JP6054371B2/ja not_active Expired - Fee Related
- 2012-03-30 WO PCT/US2012/031552 patent/WO2012138570A2/en not_active Ceased
- 2012-03-30 CA CA2832443A patent/CA2832443C/en not_active Expired - Fee Related
-
2015
- 2015-09-22 US US14/861,709 patent/US9529005B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2832443C (en) | 2020-08-25 |
| AU2012240395A1 (en) | 2013-10-24 |
| AU2012240395B2 (en) | 2016-02-04 |
| US20140093477A1 (en) | 2014-04-03 |
| US9529005B2 (en) | 2016-12-27 |
| EP2693887A2 (en) | 2014-02-12 |
| WO2012138570A3 (en) | 2012-11-29 |
| WO2012138570A2 (en) | 2012-10-11 |
| EP2693887A4 (en) | 2015-04-08 |
| JP2014512361A (ja) | 2014-05-22 |
| US9140698B2 (en) | 2015-09-22 |
| EP2693887B1 (en) | 2020-10-28 |
| US20160169921A1 (en) | 2016-06-16 |
| CA2832443A1 (en) | 2012-10-11 |
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