JP6046718B2 - 治療システム - Google Patents
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- JP6046718B2 JP6046718B2 JP2014525521A JP2014525521A JP6046718B2 JP 6046718 B2 JP6046718 B2 JP 6046718B2 JP 2014525521 A JP2014525521 A JP 2014525521A JP 2014525521 A JP2014525521 A JP 2014525521A JP 6046718 B2 JP6046718 B2 JP 6046718B2
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Description
Claims (11)
- 少なくとも1つのプロセッサであって:
対象の領域の計画画像を受信する動作であって、前記対象は標的及び/又はリスク臓器(OAR)を含み、前記対象は少なくとも1つのサロゲート及び線量計に関連付けられ、前記サロゲートは前記標的及び/又は前記OARの代用物として動作し、前記線量計は前記標的及び/又は前記OARに投与される線量を測定する、動作と;
前記標的及び/又は前記OARのうち1つ又は複数について、前記計画画像における基準の位置及び形状を決定する動作と;
前記サロゲート及び前記線量計の各々について、前記計画画像から、基準の位置及び/又は形状を決定する動作と;
前記サロゲートの前記基準の位置及び/又は形状と、前記サロゲートの現在の位置及び/又は形状との間のずれ、及び、計画した線量分布と投与された線量分布との間のずれのうちの1つ又は複数のずれを決定する動作であって、前記投与された線量分布は、前記線量計の線量測定データと前記基準の位置及び/又は形状とから決定される、動作と;
をなすようにプログラムされた、少なくとも1つのプロセッサを含み、
前記対象は、光ファイバ構造(OFS)を定義する埋め込まれた光ファイバを含み、前記サロゲートは、前記埋め込まれた光ファイバである、
治療システム。 - 前記サロゲート及び前記線量計は、前記対象の内部に埋め込まれ、前記標的、前記OAR、並びに前記標的及び/又は前記OARに隣接する組織のうちの少なくとも1つに直接的に、かつ/あるいは前記標的、前記OAR、並びに前記標的及び/又は前記OARに隣接する組織のうちの前記少なくとも1つに間接的に固定される、
請求項1に記載の治療システム。 - 前記サロゲート及び前記線量計は、前記対象の内部に埋め込まれ、シュリンクラップを用いて、前記標的、前記OAR、並びに前記標的及び/又は前記OARに隣接する組織のうちの少なくとも1つに間接的に固定される、
請求項1乃至2のうちいずれか1項に記載の治療システム。 - 前記プロセッサは、
前記サロゲートの前記基準の位置及び/又は形状を決定する動作と、
前記サロゲートの前記現在の位置及び/又は形状を示す動きデータを受信する動作と、
前記サロゲートの前記基準の位置及び/形状と、前記サロゲートの前記現在の位置及び/又は形状との間のずれを決定する動作と、
をなすようにさらにプログラムされる、
請求項1乃至3のうちいずれか1項に記載の治療システム。 - 前記プロセッサは、
前記サロゲートの前記基準の位置及び形状と、前記サロゲートの前記現在の位置及び形状との間のずれから、前記計画画像において前記標的及び/又は前記OARの現在の位置及び形状を決定する動作と、
前記標的及び/又は前記OARの前記現在の位置及び形状と、前記標的及び/又は前記OARの前記基準の位置及び形状との間のずれを決定する動作と
をなすようにさらにプログラムされる、
請求項4に記載の治療システム。 - 前記プロセッサは、
治療の投与中、前記サロゲートについて、前記計画画像における現在の位置及び/又は形状を示す動きデータを受信する動作と;
動作であって、
前記サロゲートのずれに基づいて、前記治療の投与がベースとしている治療計画を調整する動作と、
前記動きデータから、前記標的及び/又は前記OARに投与される放射線の、動き補償された推定を生成する動作と、
のうち1つ又は複数の動作と;
をなすようにさらにプログラムされる、
請求項4乃至5のうちいずれか1項に記載の治療システム。 - 前記プロセッサは、
所定の期間にわたって、複数の動きデータサンプル及び/又は複数の線量測定データサンプルを受信する動作であって、前記動きデータサンプルの各々は、前記サロゲートについて、前記計画画像における位置及び/又は形状を示し、前記線量測定データサンプルの各々は、前記標的及び/又は前記OARに投与された線量を示す、受信する動作と;
動作であって、
前記複数の動きデータサンプルから、前記標的及び/又は前記OARについての累積的な動きパターンを生成する動作と、
前記複数の動きデータサンプルと前記複数の線量測定データサンプルとの相関及び分析を通じての、動作であり、
最大の線量測定ずれを用いて、前記標的及び/又は前記OARの位置を決定する動作と、
動きパターンと線量測定ずれとの間の、患者固有の関係を決定する動作と、
のうち1つ又は複数の動作と、
のうち1つ又は複数の動作と;
をなすようにさらにプログラムされる、
請求項1乃至6のうちいずれか1項に記載の治療システム。 - 前記プロセッサは、
前記OFSの基準の位置及び形状を示す、基準の光学的動きデータを受信する動作と、
前記基準の光学的動きデータから、前記計画画像において、前記OFSの前記基準の位置及び形状を決定する動作と、
前記OFSの現在の位置及び形状を示す、現在の光学的動きデータを受信する動作と、
前記現在の光学的動きデータから、前記計画画像において、前記OFSの前記現在の位置及び形状を決定する動作と、
前記OFSの前記の決定された基準の位置及び形状と、前記OFSの前記の決定された現在の位置及び形状との間のずれを決定する動作と、
をなすようにさらにプログラムされる、
請求項1乃至7のうちいずれか1項に記載の治療システム。 - (1)前記サロゲートの前記基準の位置及び/又は形状と、(2)前記サロゲートの前記現在の位置及び/又は形状とのうち1つ又は複数が、前記光ファイバの長さに沿った種々のブラッグ波長のファイバ・ブラッグ・グレーティングを用いて決定される、
請求項1乃至8のうちいずれか1項に記載の治療システム。 - 前記対象は前記線量計を含み、前記プロセッサは、
前記線量計の前記基準の位置及び/又は形状を決定する動作と、
前記線量計から、前記標的及び/又は前記OARに投与された線量を示す、線量測定データを受信する動作と、
前記計画した線量分布と前記投与された線量分布との間のずれを決定する動作と、
をなすようにさらにプログラムされる、
請求項1乃至9のうちいずれか1項に記載の治療システム。 - 前記ずれは、治療の投与に使用され、前記治療は、アブレーション療法、小線源療法、X線療法、プロトン療法、及び高密度焦点式超音波(HIFU)療法のうち1つを含む、
請求項1乃至10のうちいずれか1項に記載の治療システム。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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US201161523887P | 2011-08-16 | 2011-08-16 | |
US61/523,887 | 2011-08-16 | ||
US201261602112P | 2012-02-23 | 2012-02-23 | |
US61/602,112 | 2012-02-23 | ||
PCT/IB2012/053752 WO2013024380A1 (en) | 2011-08-16 | 2012-07-24 | Method to estimate interfractional and intrafractional organ motion for adaptive external beam radiotherapy |
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JP2014528767A JP2014528767A (ja) | 2014-10-30 |
JP6046718B2 true JP6046718B2 (ja) | 2016-12-21 |
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JP2014525521A Active JP6046718B2 (ja) | 2011-08-16 | 2012-07-24 | 治療システム |
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US (1) | US9259155B2 (ja) |
EP (1) | EP2744566B1 (ja) |
JP (1) | JP6046718B2 (ja) |
CN (1) | CN103889506B (ja) |
MX (1) | MX2014001659A (ja) |
WO (1) | WO2013024380A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2017514616A (ja) * | 2014-05-06 | 2017-06-08 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 治療計画システム |
WO2022231147A1 (ko) * | 2021-04-30 | 2022-11-03 | 연세대학교 산학협력단 | 방사선량 측정 자동 평가 방법 및 장치 |
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US9833637B2 (en) | 2011-05-02 | 2017-12-05 | Radiadyne Llc | Skin patch dosimeter |
WO2013144736A1 (en) * | 2012-03-26 | 2013-10-03 | Koninklijke Philips N.V. | System for planning radiation treatment therapy |
US9649508B2 (en) | 2012-09-13 | 2017-05-16 | Emory University | Methods, systems and computer readable storage media storing instructions for determining patient specific treatment planning margins |
WO2014191960A1 (en) * | 2013-05-31 | 2014-12-04 | Landauer, Inc. | System for wireless, motion and position-sensing, integrating radiation sensor and energy harvester for occupational and environmental dosimetry |
US10737116B2 (en) | 2013-08-07 | 2020-08-11 | Koninklijke Philips N.V. | Therapy planning |
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