JP6018637B2 - 放射性医薬品合成装置のための較正及び正規化システム及び方法 - Google Patents

放射性医薬品合成装置のための較正及び正規化システム及び方法 Download PDF

Info

Publication number
JP6018637B2
JP6018637B2 JP2014533396A JP2014533396A JP6018637B2 JP 6018637 B2 JP6018637 B2 JP 6018637B2 JP 2014533396 A JP2014533396 A JP 2014533396A JP 2014533396 A JP2014533396 A JP 2014533396A JP 6018637 B2 JP6018637 B2 JP 6018637B2
Authority
JP
Japan
Prior art keywords
activity
synthesizer
data
activity detector
calibration standard
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2014533396A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015504412A5 (enExample
JP2015504412A (ja
Inventor
エンゲル，トルグリム
グリッグ，ジュリアン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of JP2015504412A publication Critical patent/JP2015504412A/ja
Publication of JP2015504412A5 publication Critical patent/JP2015504412A5/ja
Application granted granted Critical
Publication of JP6018637B2 publication Critical patent/JP6018637B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G01T7/005—Details of radiation-measuring instruments calibration techniques
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2014533396A 2011-09-30 2012-09-28 放射性医薬品合成装置のための較正及び正規化システム及び方法 Active JP6018637B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161541246P 2011-09-30 2011-09-30
US61/541,246 2011-09-30
PCT/US2012/057930 WO2013049577A1 (en) 2011-09-30 2012-09-28 Calibration and normalization systems and methods for radiopharmaceutical synthesizers

Publications (3)

Publication Number Publication Date
JP2015504412A JP2015504412A (ja) 2015-02-12
JP2015504412A5 JP2015504412A5 (enExample) 2015-11-12
JP6018637B2 true JP6018637B2 (ja) 2016-11-02

Family

ID=47178861

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014533396A Active JP6018637B2 (ja) 2011-09-30 2012-09-28 放射性医薬品合成装置のための較正及び正規化システム及び方法

Country Status (7)

Country Link
US (1) US9523778B2 (enExample)
EP (1) EP2760808B1 (enExample)
JP (1) JP6018637B2 (enExample)
CN (1) CN103958445B (enExample)
AU (1) AU2012315757B9 (enExample)
ES (1) ES2562656T3 (enExample)
WO (1) WO2013049577A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201418899D0 (en) * 2014-10-23 2014-12-10 Univ Hull System for radiopharmaceutical production
GB201418893D0 (en) 2014-10-23 2014-12-10 Univ Hull Monolithic body
GB201418897D0 (en) 2014-10-23 2014-12-10 Univ Hull Methods and apparatus for the analysis of compounds
US10245002B2 (en) * 2017-08-01 2019-04-02 Siemens Medical Solutions Usa, Inc. Isotope specific calibration of a dose calibrator for quantitative functional imaging
CA3134278C (en) * 2018-03-07 2023-08-29 Siemens Medical Solutions Usa, Inc Calibration bias reduction in a pressurized gas ion chanber-based dose calibrator
CN112106148B (zh) * 2018-03-28 2024-10-29 布拉科诊断公司 放射性同位素发生器寿命的早期检测
GB201805283D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Method of synthesizing a radiopharmaceutical
US11615882B2 (en) 2018-11-07 2023-03-28 Ge Healthcare Limited Apparatus, non-transitory computer-readable storage medium, and computer-implemented method for distributed ledger management of nuclear medicine products

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1620373T3 (da) 2003-05-07 2008-07-28 Bayer Schering Pharma Ag Apparat og fremgangsmåde til nucleofil fluorering
SE0301508D0 (sv) * 2003-05-23 2003-05-23 Goergen Nilsson Method for pre treatment verification in intensity modulates radiation therapy
US20070040115A1 (en) * 2005-08-05 2007-02-22 Publicover Julia G Method for calibrating particle beam energy
US9056200B2 (en) 2008-06-06 2015-06-16 Bayer Medical Care Inc. Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US8214159B2 (en) 2008-12-04 2012-07-03 Siemens Medical Solutions Usa, Inc. Apparatus and method for automated quality control
GB0905328D0 (en) * 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives
WO2011127469A1 (en) * 2010-04-09 2011-10-13 Medrad, Inc. Radiopharmaceutical concentration measurement system and method

Also Published As

Publication number Publication date
CN103958445B (zh) 2015-12-09
ES2562656T3 (es) 2016-03-07
US9523778B2 (en) 2016-12-20
EP2760808B1 (en) 2015-11-18
JP2015504412A (ja) 2015-02-12
AU2012315757A1 (en) 2014-04-17
CN103958445A (zh) 2014-07-30
AU2012315757B9 (en) 2018-01-25
US20140243500A1 (en) 2014-08-28
WO2013049577A1 (en) 2013-04-04
EP2760808A1 (en) 2014-08-06
AU2012315757A9 (en) 2018-02-01
AU2012315757B2 (en) 2017-11-23

Similar Documents

Publication Publication Date Title
JP6018637B2 (ja) 放射性医薬品合成装置のための較正及び正規化システム及び方法
US10758887B2 (en) Method of operating an automated radiopharmaceutical synthesizer
US11170884B2 (en) Control system for radiopharmaceuticals
RU2685087C2 (ru) Обнаружение ядерных изотопов в реальном времени
JP2012511153A (ja) 自動品質管理装置および自動品質管理方法
Sharma PET radiopharmaceuticals for personalized medicine
JP7766070B2 (ja) 放射性医薬品を合成する方法
Damuka et al. Method to development of PET radiopharmaceutical for cancer imaging
Fadzil et al. Upgrades and regulatory aspects of [18F] Fluorodeoxyglucose ([18F] FDG) production using the FASTLab2 synthesizer
Schopf et al. Automation of a positron-emission tomography (PET) radiotracer synthesis protocol for clinical production
Myburgh et al. Fully automated production of [11C] PiB for clinical use on Trasis-AllinOne synthesizer module
Zagni et al. The concept of minimum detectable activity of radionuclide activity meters and their suitability for routine quality control of radiopharmaceuticals. An experimental study

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150918

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150918

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160906

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160930

R150 Certificate of patent or registration of utility model

Ref document number: 6018637

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250