CN103958445B - 用于放射性药物合成器的校准和归一化系统和方法 - Google Patents

用于放射性药物合成器的校准和归一化系统和方法 Download PDF

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Publication number
CN103958445B
CN103958445B CN201280059332.6A CN201280059332A CN103958445B CN 103958445 B CN103958445 B CN 103958445B CN 201280059332 A CN201280059332 A CN 201280059332A CN 103958445 B CN103958445 B CN 103958445B
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activity
synthesizer
activity detector
data
calibration standard
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Chinese (zh)
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CN103958445A (zh
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T.恩格尔
J.格里格
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G01T7/005—Details of radiation-measuring instruments calibration techniques
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201280059332.6A 2011-09-30 2012-09-28 用于放射性药物合成器的校准和归一化系统和方法 Active CN103958445B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161541246P 2011-09-30 2011-09-30
US61/541246 2011-09-30
US61/541,246 2011-09-30
PCT/US2012/057930 WO2013049577A1 (en) 2011-09-30 2012-09-28 Calibration and normalization systems and methods for radiopharmaceutical synthesizers

Publications (2)

Publication Number Publication Date
CN103958445A CN103958445A (zh) 2014-07-30
CN103958445B true CN103958445B (zh) 2015-12-09

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CN201280059332.6A Active CN103958445B (zh) 2011-09-30 2012-09-28 用于放射性药物合成器的校准和归一化系统和方法

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Country Link
US (1) US9523778B2 (enExample)
EP (1) EP2760808B1 (enExample)
JP (1) JP6018637B2 (enExample)
CN (1) CN103958445B (enExample)
AU (1) AU2012315757B9 (enExample)
ES (1) ES2562656T3 (enExample)
WO (1) WO2013049577A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201418899D0 (en) * 2014-10-23 2014-12-10 Univ Hull System for radiopharmaceutical production
GB201418893D0 (en) 2014-10-23 2014-12-10 Univ Hull Monolithic body
GB201418897D0 (en) 2014-10-23 2014-12-10 Univ Hull Methods and apparatus for the analysis of compounds
US10245002B2 (en) * 2017-08-01 2019-04-02 Siemens Medical Solutions Usa, Inc. Isotope specific calibration of a dose calibrator for quantitative functional imaging
CA3134278C (en) * 2018-03-07 2023-08-29 Siemens Medical Solutions Usa, Inc Calibration bias reduction in a pressurized gas ion chanber-based dose calibrator
CN112106148B (zh) * 2018-03-28 2024-10-29 布拉科诊断公司 放射性同位素发生器寿命的早期检测
GB201805283D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Method of synthesizing a radiopharmaceutical
US11615882B2 (en) 2018-11-07 2023-03-28 Ge Healthcare Limited Apparatus, non-transitory computer-readable storage medium, and computer-implemented method for distributed ledger management of nuclear medicine products

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100490A2 (de) * 2003-05-07 2004-11-18 Schering Ag Vorrichtung und verfahren zum nucleophilen fluorieren
CN1791807A (zh) * 2003-05-23 2006-06-21 格尔根·尼尔森 放射疗法中的治疗前验证方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070040115A1 (en) * 2005-08-05 2007-02-22 Publicover Julia G Method for calibrating particle beam energy
US9056200B2 (en) 2008-06-06 2015-06-16 Bayer Medical Care Inc. Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US8214159B2 (en) 2008-12-04 2012-07-03 Siemens Medical Solutions Usa, Inc. Apparatus and method for automated quality control
GB0905328D0 (en) * 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives
WO2011127469A1 (en) * 2010-04-09 2011-10-13 Medrad, Inc. Radiopharmaceutical concentration measurement system and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100490A2 (de) * 2003-05-07 2004-11-18 Schering Ag Vorrichtung und verfahren zum nucleophilen fluorieren
CN1791807A (zh) * 2003-05-23 2006-06-21 格尔根·尼尔森 放射疗法中的治疗前验证方法

Also Published As

Publication number Publication date
ES2562656T3 (es) 2016-03-07
US9523778B2 (en) 2016-12-20
EP2760808B1 (en) 2015-11-18
JP2015504412A (ja) 2015-02-12
AU2012315757A1 (en) 2014-04-17
JP6018637B2 (ja) 2016-11-02
CN103958445A (zh) 2014-07-30
AU2012315757B9 (en) 2018-01-25
US20140243500A1 (en) 2014-08-28
WO2013049577A1 (en) 2013-04-04
EP2760808A1 (en) 2014-08-06
AU2012315757A9 (en) 2018-02-01
AU2012315757B2 (en) 2017-11-23

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