JP6009357B2 - アデノウイルスベクターの生産方法およびそれによって生成されるウイルス調製物 - Google Patents
アデノウイルスベクターの生産方法およびそれによって生成されるウイルス調製物 Download PDFInfo
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| US8071740B2 (en) * | 2000-11-17 | 2011-12-06 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
| AU2003222427B8 (en) | 2000-11-17 | 2010-04-29 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same |
| EP1436313B1 (en) | 2001-10-19 | 2010-09-22 | Vascular Biogenics Ltd. | Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy |
| WO2008015675A2 (en) | 2006-07-31 | 2008-02-07 | Vascular Biogenics Ltd. | Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia |
| MX342641B (es) | 2010-01-05 | 2016-10-07 | Vascular Biogenics Ltd | Metodos para uso de un agente adenoviral anti-angiogenico especifico. |
| MX338931B (es) | 2010-01-05 | 2016-05-06 | Vascular Biogenics Ltd | Composiciones y metodo para tratar gliobastoma (gbm). |
| KR101989171B1 (ko) * | 2012-10-17 | 2019-06-14 | 바스큘라 바이오제닉스 리미티드 | 아데노바이러스를 사용하는 치료 방법 |
| CN103012591B (zh) * | 2012-12-12 | 2014-05-14 | 武汉吉爱生物技术有限公司 | 抗Benzonase单克隆抗体、其制备方法和应用 |
| US9682154B2 (en) | 2013-02-04 | 2017-06-20 | Vascular Biogenics Ltd. | Methods of inducing responsiveness to anti-angiogenic agent |
| PT2970920T (pt) * | 2013-03-15 | 2018-07-30 | Childrens Hospital Philadelphia | Processo de fabrico escalável para produzir vetores lentivirais recombinantes em sistema de cultura de células de suspensão livres de soro |
| CN107603956A (zh) * | 2017-08-24 | 2018-01-19 | 乾元浩生物股份有限公司 | 一种禽腺病毒纸片载体潮汐式悬浮培养方法 |
| CN107630004B (zh) * | 2017-09-01 | 2021-01-15 | 康希诺生物股份公司 | 降低可复制性腺病毒产生的细胞株及构建方法和应用 |
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| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
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| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| US5747340A (en) | 1994-06-03 | 1998-05-05 | Syntex (U.S.A.) Inc. | Targeted gene expression using preproendothelin-1 promoters |
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| EP0968284B1 (en) * | 1996-11-20 | 2006-12-13 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| AU779267B2 (en) * | 1998-12-31 | 2005-01-13 | Centelion S.A.S. | Method for separating viral particles |
| US6168941B1 (en) * | 2000-04-07 | 2001-01-02 | Genvec, Inc. | Method of producing adenoviral vector stocks |
| US20070286845A1 (en) * | 2000-11-17 | 2007-12-13 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
| WO2003039459A2 (en) * | 2001-11-05 | 2003-05-15 | Genvec, Inc. | Viral vector production methods and compositions |
| US7459154B2 (en) * | 2002-12-26 | 2008-12-02 | Cell Genesys, Inc. | Methods and reagents for the enhancement of virus transduction in the bladder epithelium |
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