SG10201500015TA - Methods of producing adenovirus vectors and viral preparations generated thereby - Google Patents

Methods of producing adenovirus vectors and viral preparations generated thereby

Info

Publication number
SG10201500015TA
SG10201500015TA SG10201500015TA SG10201500015TA SG10201500015TA SG 10201500015T A SG10201500015T A SG 10201500015TA SG 10201500015T A SG10201500015T A SG 10201500015TA SG 10201500015T A SG10201500015T A SG 10201500015TA SG 10201500015T A SG10201500015T A SG 10201500015TA
Authority
SG
Singapore
Prior art keywords
methods
adenovirus vectors
viral preparations
producing adenovirus
preparations generated
Prior art date
Application number
SG10201500015TA
Inventor
Livnat Bangio
Naamit Sher
Eyal Breitbart
Original Assignee
Vascular Biogenics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vascular Biogenics Ltd filed Critical Vascular Biogenics Ltd
Publication of SG10201500015TA publication Critical patent/SG10201500015TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
SG10201500015TA 2010-01-12 2011-01-12 Methods of producing adenovirus vectors and viral preparations generated thereby SG10201500015TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29415810P 2010-01-12 2010-01-12

Publications (1)

Publication Number Publication Date
SG10201500015TA true SG10201500015TA (en) 2015-02-27

Family

ID=43982270

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201500015TA SG10201500015TA (en) 2010-01-12 2011-01-12 Methods of producing adenovirus vectors and viral preparations generated thereby
SG2012051496A SG182490A1 (en) 2010-01-12 2011-01-12 Methods of producing adenovirus vectors and viral preparations generated thereby

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2012051496A SG182490A1 (en) 2010-01-12 2011-01-12 Methods of producing adenovirus vectors and viral preparations generated thereby

Country Status (6)

Country Link
US (2) US20130052165A1 (en)
EP (1) EP2523681A1 (en)
JP (1) JP6009357B2 (en)
IL (1) IL220922B (en)
SG (2) SG10201500015TA (en)
WO (1) WO2011086509A1 (en)

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US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) * 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
EP1436313B1 (en) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
CN101516902B (en) 2006-07-31 2012-08-08 脉管生物生长有限公司 Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia
CA2786377C (en) 2010-01-05 2018-02-27 Vascular Biogenics Ltd. Compositions and methods for treating malignant gliomas employing viral vectors encoding a fas-chimera
KR101754437B1 (en) 2010-01-05 2017-07-05 바스큘라 바이오제닉스 리미티드 Methods for use of a specific anti-angiogenic adenoviral agent
AU2013333571B2 (en) 2012-10-17 2017-01-19 Vascular Biogenics Ltd. Treatment methods using adenovirus
CN103012591B (en) * 2012-12-12 2014-05-14 武汉吉爱生物技术有限公司 Monoclonal antibody for resisting Benzonase, and preparation method and application thereof
WO2014118643A2 (en) 2013-02-04 2014-08-07 Vascular Biogenics Ltd. Methods of inducing responsiveness to anti-angiogenic agent
CN105378074A (en) * 2013-03-15 2016-03-02 费城儿童医院 Scalable manufacturing process to produce recombinant lentiviral vectors in serum-free suspension cell culture system
CN107603956A (en) * 2017-08-24 2018-01-19 乾元浩生物股份有限公司 A kind of aviadenovirus scraps of paper carrier tidal type suspension culture method
CN107630004B (en) * 2017-09-01 2021-01-15 康希诺生物股份公司 Cell strain for reducing generation of replication-competent adenovirus and construction method and application thereof

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Also Published As

Publication number Publication date
JP2013516978A (en) 2013-05-16
IL220922B (en) 2019-03-31
EP2523681A1 (en) 2012-11-21
US20130295053A1 (en) 2013-11-07
US20130052165A1 (en) 2013-02-28
SG182490A1 (en) 2012-08-30
WO2011086509A1 (en) 2011-07-21
JP6009357B2 (en) 2016-10-19

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