JP6007105B2 - ワクチン組成物 - Google Patents

ワクチン組成物 Download PDF

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Publication number
JP6007105B2
JP6007105B2 JP2012545493A JP2012545493A JP6007105B2 JP 6007105 B2 JP6007105 B2 JP 6007105B2 JP 2012545493 A JP2012545493 A JP 2012545493A JP 2012545493 A JP2012545493 A JP 2012545493A JP 6007105 B2 JP6007105 B2 JP 6007105B2
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JP
Japan
Prior art keywords
klh
composition
peptide
linker
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012545493A
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English (en)
Japanese (ja)
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JP2013515049A5 (https=
JP2013515049A (ja
Inventor
シード サレーム アハメド
シード サレーム アハメド
サード ジョン ジョゼフ バックリー
サード ジョン ジョゼフ バックリー
ラビニア マリナ ルイス
ラビニア マリナ ルイス
ブランディ レイ オズボーン
ブランディ レイ オズボーン
サンディッパン シンハ
サンディッパン シンハ
ジェニファー マリー ソーン
ジェニファー マリー ソーン
フェルハナ ザマン
フェルハナ ザマン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celldex Therapeutics Inc
Original Assignee
Avant Immunotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avant Immunotherapeutics Inc filed Critical Avant Immunotherapeutics Inc
Publication of JP2013515049A publication Critical patent/JP2013515049A/ja
Publication of JP2013515049A5 publication Critical patent/JP2013515049A5/ja
Application granted granted Critical
Publication of JP6007105B2 publication Critical patent/JP6007105B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001104Epidermal growth factor receptors [EGFR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/62Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012545493A 2009-12-22 2010-12-08 ワクチン組成物 Expired - Fee Related JP6007105B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28908309P 2009-12-22 2009-12-22
US61/289,083 2009-12-22
PCT/IB2010/055674 WO2011077309A2 (en) 2009-12-22 2010-12-08 Vaccine compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015105966A Division JP6146927B2 (ja) 2009-12-22 2015-05-26 ワクチン組成物

Publications (3)

Publication Number Publication Date
JP2013515049A JP2013515049A (ja) 2013-05-02
JP2013515049A5 JP2013515049A5 (https=) 2014-01-30
JP6007105B2 true JP6007105B2 (ja) 2016-10-12

Family

ID=43797591

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012545493A Expired - Fee Related JP6007105B2 (ja) 2009-12-22 2010-12-08 ワクチン組成物
JP2015105966A Expired - Fee Related JP6146927B2 (ja) 2009-12-22 2015-05-26 ワクチン組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015105966A Expired - Fee Related JP6146927B2 (ja) 2009-12-22 2015-05-26 ワクチン組成物

Country Status (13)

Country Link
US (3) US20130034573A1 (https=)
EP (2) EP3257525A3 (https=)
JP (2) JP6007105B2 (https=)
KR (1) KR20120120185A (https=)
CN (2) CN102762224A (https=)
AU (1) AU2010334428B2 (https=)
CA (1) CA2785585A1 (https=)
IL (1) IL220308A0 (https=)
MX (1) MX337070B (https=)
NZ (2) NZ600978A (https=)
RU (1) RU2581020C2 (https=)
SG (2) SG181628A1 (https=)
WO (1) WO2011077309A2 (https=)

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CA2790401C (en) * 2010-02-21 2018-05-29 Bayer Healthcare Llc Method for activation and conjugation of biomolecules
KR101502360B1 (ko) * 2013-03-20 2015-03-25 주식회사 옵티팜 신규한 국내형 돼지생식기호흡기증후군 바이러스
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
EP3823677A4 (en) * 2018-07-19 2022-06-01 Helixmith Co., Ltd. LYOPHILIZED PHARMACEUTICAL COMPOSITIONS FOR NAKED DNA GENE THERAPY
US20220273755A1 (en) * 2019-11-21 2022-09-01 Multiple Fortune Holding Limited Pharmaceutical composition, use and method for applying ganoderma microsporum immunomodulatory protein and keyhole limpet hemocyanin in carcinoma treatment

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Also Published As

Publication number Publication date
AU2010334428A1 (en) 2012-07-05
WO2011077309A3 (en) 2011-10-06
RU2581020C2 (ru) 2016-04-10
SG10201408505SA (en) 2015-02-27
JP2015180667A (ja) 2015-10-15
AU2010334428B2 (en) 2015-05-21
MX337070B (es) 2016-02-11
EP2515934B1 (en) 2017-05-17
SG181628A1 (en) 2012-07-30
NZ600978A (en) 2014-08-29
RU2012131162A (ru) 2014-01-27
NZ629256A (en) 2016-02-26
MX2012007283A (es) 2012-07-30
KR20120120185A (ko) 2012-11-01
CA2785585A1 (en) 2011-06-30
CN107412754A (zh) 2017-12-01
WO2011077309A2 (en) 2011-06-30
EP3257525A3 (en) 2018-02-28
IL220308A0 (en) 2012-07-31
EP2515934A2 (en) 2012-10-31
JP6146927B2 (ja) 2017-06-14
US20130034573A1 (en) 2013-02-07
US20150087815A1 (en) 2015-03-26
EP3257525A2 (en) 2017-12-20
US20190365886A1 (en) 2019-12-05
JP2013515049A (ja) 2013-05-02
CN102762224A (zh) 2012-10-31

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