JP5957450B2 - 生物学的流体中の、中間体及びタンパク質結合尿毒症毒素の含有量を決定するための方法及び装置 - Google Patents

生物学的流体中の、中間体及びタンパク質結合尿毒症毒素の含有量を決定するための方法及び装置 Download PDF

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JP5957450B2
JP5957450B2 JP2013517023A JP2013517023A JP5957450B2 JP 5957450 B2 JP5957450 B2 JP 5957450B2 JP 2013517023 A JP2013517023 A JP 2013517023A JP 2013517023 A JP2013517023 A JP 2013517023A JP 5957450 B2 JP5957450 B2 JP 5957450B2
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fluorescence
dialysis
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JP2013534630A (ja
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フリドリン，イヴォ
ウーリン，フレドリック
イエロトスカヤ，ジャナ
タンネール，リスト
アルンド，ユルゲン
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オプトフルイド テクノロジーズ オーユー
オプトフルイド テクノロジーズ オーユー
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00

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  • Biotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
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JP2013517023A 2010-06-28 2011-06-28 生物学的流体中の、中間体及びタンパク質結合尿毒症毒素の含有量を決定するための方法及び装置 Active JP5957450B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EEP201000056A EE05676B1 (et) 2010-06-28 2010-06-28 Optiline meetod ja seade keskmise suurusega ja valkudega seotud ureemiliste toksiinide m„„ramiseks bioloogilistes vedelikes
EEP201000056 2010-06-28
EEP201000085 2010-12-10
EEP201000085A EE05669B1 (et) 2010-12-10 2010-12-10 Optiline meetod ja seade keskmise suurusega ja valkudega seotud ureemiliste toksiinide m„„ramiseks bioloogilistes vedelikes
PCT/EE2011/000008 WO2012000521A1 (en) 2010-06-28 2011-06-28 A method and device for determining content of the middle and protein bound uremic toxins in a biological fluid

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JP2013534630A JP2013534630A (ja) 2013-09-05
JP2013534630A5 JP2013534630A5 (enExample) 2014-08-07
JP5957450B2 true JP5957450B2 (ja) 2016-07-27

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US (1) US9103789B2 (enExample)
EP (1) EP2585830B1 (enExample)
JP (1) JP5957450B2 (enExample)
KR (1) KR101848527B1 (enExample)
CN (1) CN102985822A (enExample)
AU (1) AU2011274009B2 (enExample)
BR (1) BR112012033625A2 (enExample)
CA (1) CA2837488C (enExample)
NZ (1) NZ605685A (enExample)
WO (1) WO2012000521A1 (enExample)

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DE102012112790A1 (de) * 2012-12-20 2014-06-26 B. Braun Avitum Ag Verfahren und Vorrichtung zur Bestimmung von Abfallprodukten wie Indoxyl Sulfate in der Dialyse
US10150983B2 (en) * 2013-02-19 2018-12-11 Nipro Corporation Method for measuring indoxyl sulfuric acid
CN104991026A (zh) * 2015-06-29 2015-10-21 苏州东辰林达检测技术有限公司 尿液中甲基马尿酸的检测方法
EP3537135A1 (en) * 2018-03-05 2019-09-11 Tallinn University of Technology A device and method for assessment of a concentration of free pentosidine in a spent dialysate
JP7207702B2 (ja) * 2018-11-06 2023-01-18 国立研究開発法人農業・食品産業技術総合研究機構 成分抽出方法、蛍光指紋測定装置、及びコンピュータが実行可能なプログラム
GB202104698D0 (en) * 2021-03-31 2021-05-12 Tallinn Univ Of Technology Multiparametric optical method and apparatus for the determination of uremic solutes, including uremic toxins, in biological fluids
TWI838830B (zh) * 2022-04-08 2024-04-11 財團法人工業技術研究院 β2-微球蛋白濃度的分析方法及裝置
CN120948421A (zh) * 2025-10-15 2025-11-14 天津医科大学 一种定量-判别一体化尿毒症智能检测系统

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JP3261264B2 (ja) 1994-07-13 2002-02-25 株式会社堀場製作所 多成分水溶液の分析方法およびその分析装置
WO1998019592A1 (en) * 1996-11-01 1998-05-14 Rio Grande Medical Technologies, Inc. Dialysis monitoring method and apparatus
US6261848B1 (en) * 1998-05-08 2001-07-17 The Johns Hopkins University Miniature immuno-optical rapid analyte sensor platform
SE525639C2 (sv) 1998-06-04 2005-03-22 Thore Falkvall Bestämning av slaggprodukter i dialysvätska med hjälp av optisk sensor
AUPR748501A0 (en) * 2001-09-04 2001-09-27 Life Therapeutics Limited Renal dialysis
US8337444B2 (en) * 2001-05-22 2012-12-25 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis
RU2212029C1 (ru) 2001-12-03 2003-09-10 Общество с ограниченной ответственностью "Клиника экстракорпоральной гемокоррекции" Способ анализа жидкой биологической среды в процессе мониторинга
US7002670B2 (en) * 2002-06-12 2006-02-21 Baxter International Inc. Optical sensor and method for measuring concentration of a chemical constituent using its intrinsic optical absorbance
EP1643240A4 (en) * 2003-07-03 2010-09-22 Wako Pure Chem Ind Ltd METHOD FOR MEASURING CERTAIN COMPONENTS BY MEANS OF SPECTRAL MEASUREMENT
US7427508B2 (en) 2003-10-09 2008-09-23 Organotek Defense System Corporation Method for assaying multi-component mixtures
WO2005069737A2 (en) * 2004-01-27 2005-08-04 Ramot At Tel Aviv University Ltd. Method and system for detecting analytes
EP1751523B1 (en) 2004-05-13 2017-10-04 NarTest AS A portable device and method for on-site detection and quantification of drugs
US7966051B2 (en) * 2005-01-11 2011-06-21 Olympus Corporation Fluorescent agent concentration measuring apparatus, dose control apparatus, administration system, fluorescent agent concentration measuring method, and dose control method
DE102005020384A1 (de) * 2005-05-02 2006-11-09 Therainvention Gmbh Spektroskopisches Verfahren zum Nachweis von Analyten
WO2009071102A1 (en) 2007-12-04 2009-06-11 Tallinn University Of Technology Optical method and device for measuring concentrations of substances in biological fluids

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AU2011274009B2 (en) 2016-06-23
WO2012000521A1 (en) 2012-01-05
EP2585830A1 (en) 2013-05-01
EP2585830B1 (en) 2018-04-25
US20130193347A1 (en) 2013-08-01
CA2837488A1 (en) 2012-01-05
CN102985822A (zh) 2013-03-20
BR112012033625A2 (pt) 2016-10-25
JP2013534630A (ja) 2013-09-05
US9103789B2 (en) 2015-08-11
KR101848527B1 (ko) 2018-04-12
NZ605685A (en) 2014-10-31
AU2011274009A1 (en) 2013-01-31
KR20130038347A (ko) 2013-04-17
CA2837488C (en) 2021-10-26

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