JP5931757B2 - 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物 - Google Patents

嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物 Download PDF

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JP5931757B2
JP5931757B2 JP2012557033A JP2012557033A JP5931757B2 JP 5931757 B2 JP5931757 B2 JP 5931757B2 JP 2012557033 A JP2012557033 A JP 2012557033A JP 2012557033 A JP2012557033 A JP 2012557033A JP 5931757 B2 JP5931757 B2 JP 5931757B2
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capsule
therapeutic agent
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JP2013522194A (ja
JP2013522194A5 (enExample
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ミア エー． イムラン，
ミア エー． イムラン，
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インキューブ ラブズ， エルエルシー
インキューブ ラブズ， エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Medicinal compositions released by microdevices, e.g. microelectromechanical systems [MEMS], microdevices comprising chips or microdevices on silicon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2012557033A 2010-03-10 2010-12-23 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物 Active JP5931757B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33994110P 2010-03-10 2010-03-10
US61/339,941 2010-03-10
PCT/US2010/062073 WO2011112229A2 (en) 2010-03-10 2010-12-23 Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

Related Child Applications (1)

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JP2015127337A Division JP6118371B2 (ja) 2010-03-10 2015-06-25 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物

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JP2013522194A JP2013522194A (ja) 2013-06-13
JP2013522194A5 JP2013522194A5 (enExample) 2014-02-20
JP5931757B2 true JP5931757B2 (ja) 2016-06-08

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JP2012557033A Active JP5931757B2 (ja) 2010-03-10 2010-12-23 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物
JP2015127337A Active JP6118371B2 (ja) 2010-03-10 2015-06-25 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物
JP2017059281A Withdrawn JP2017105854A (ja) 2010-03-10 2017-03-24 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物
JP2018145276A Pending JP2018165281A (ja) 2010-03-10 2018-08-01 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物

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JP2015127337A Active JP6118371B2 (ja) 2010-03-10 2015-06-25 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物
JP2017059281A Withdrawn JP2017105854A (ja) 2010-03-10 2017-03-24 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物
JP2018145276A Pending JP2018165281A (ja) 2010-03-10 2018-08-01 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物

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EP (2) EP2544668B1 (enExample)
JP (4) JP5931757B2 (enExample)
CN (2) CN105168174B (enExample)
AU (3) AU2010347732A1 (enExample)
CA (1) CA2792862C (enExample)
WO (1) WO2011112229A2 (enExample)

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JP2015166392A (ja) * 2010-03-10 2015-09-24 インキューブ ラブズ， エルエルシー 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015166392A (ja) * 2010-03-10 2015-09-24 インキューブ ラブズ， エルエルシー 嚥下可能な薬物送達デバイスを用いた腸管の内腔への送達のための治療薬調製物

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CA2792862A1 (en) 2011-09-15
JP2017105854A (ja) 2017-06-15
CN103025319B (zh) 2015-07-01
CN103025319A (zh) 2013-04-03
EP2544668A2 (en) 2013-01-16
AU2016250444A1 (en) 2016-11-17
JP2013522194A (ja) 2013-06-13
AU2019201724A1 (en) 2019-04-04
JP2018165281A (ja) 2018-10-25
WO2011112229A2 (en) 2011-09-15
AU2019201724B2 (en) 2020-07-16
JP6118371B2 (ja) 2017-04-19
CN105168174A (zh) 2015-12-23
EP2544668B1 (en) 2019-07-10
EP3603624A1 (en) 2020-02-05
AU2016250444B2 (en) 2018-12-20
CA2792862C (en) 2018-03-06
EP2544668A4 (en) 2013-11-27
WO2011112229A3 (en) 2011-11-24
AU2010347732A1 (en) 2012-10-04
JP2015166392A (ja) 2015-09-24
CN105168174B (zh) 2019-01-08

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