JP5913785B2 - 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 - Google Patents
乳癌の遠隔転移を予測するための分子予後サインおよびその使用 Download PDFInfo
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- JP5913785B2 JP5913785B2 JP2009548313A JP2009548313A JP5913785B2 JP 5913785 B2 JP5913785 B2 JP 5913785B2 JP 2009548313 A JP2009548313 A JP 2009548313A JP 2009548313 A JP2009548313 A JP 2009548313A JP 5913785 B2 JP5913785 B2 JP 5913785B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89896307P | 2007-01-31 | 2007-01-31 | |
| US60/898,963 | 2007-01-31 | ||
| PCT/US2008/001339 WO2008094678A2 (en) | 2007-01-31 | 2008-01-31 | A molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013124548A Division JP2013176397A (ja) | 2007-01-31 | 2013-06-13 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010516292A JP2010516292A (ja) | 2010-05-20 |
| JP2010516292A5 JP2010516292A5 (enExample) | 2015-02-26 |
| JP5913785B2 true JP5913785B2 (ja) | 2016-05-25 |
Family
ID=39674722
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548313A Active JP5913785B2 (ja) | 2007-01-31 | 2008-01-31 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
| JP2013124548A Withdrawn JP2013176397A (ja) | 2007-01-31 | 2013-06-13 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
| JP2015237175A Withdrawn JP2016032480A (ja) | 2007-01-31 | 2015-12-04 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013124548A Withdrawn JP2013176397A (ja) | 2007-01-31 | 2013-06-13 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
| JP2015237175A Withdrawn JP2016032480A (ja) | 2007-01-31 | 2015-12-04 | 乳癌の遠隔転移を予測するための分子予後サインおよびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US7695915B2 (enExample) |
| EP (2) | EP2520668B1 (enExample) |
| JP (3) | JP5913785B2 (enExample) |
| CA (1) | CA2674907C (enExample) |
| WO (1) | WO2008094678A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080286273A1 (en) * | 2007-05-02 | 2008-11-20 | Siemens Medical Solutions Usa, Inc. | Knowledge-Based Proliferation Signatures and Methods of Use |
| US7960114B2 (en) | 2007-05-02 | 2011-06-14 | Siemens Medical Solutions Usa, Inc. | Gene signature of early hypoxia to predict patient survival |
| US20090203015A1 (en) * | 2008-02-13 | 2009-08-13 | Celera Corporation | Multiplex assays for hormonal and growth factor receptors, and uses thereof |
| EP2352847B1 (en) | 2008-11-10 | 2014-01-08 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Gene signature for predicting prognosis of patients with solid tumors |
| GB0821787D0 (en) * | 2008-12-01 | 2009-01-07 | Univ Ulster | A genomic-based method of stratifying breast cancer patients |
| WO2011039734A2 (en) * | 2009-10-02 | 2011-04-07 | Enzo Medico | Use of genes involved in anchorage independence for the optimization of diagnosis and treatment of human cancer |
| WO2011151061A1 (en) * | 2010-06-03 | 2011-12-08 | Ipsen Pharma S.A.S. | Al035301, a biomarker for breast cancer |
| WO2012009382A2 (en) * | 2010-07-12 | 2012-01-19 | The Regents Of The University Of Colorado | Molecular indicators of bladder cancer prognosis and prediction of treatment response |
| US8557525B1 (en) | 2011-02-25 | 2013-10-15 | Celera Corporation | Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof |
| US10519505B2 (en) * | 2011-04-28 | 2019-12-31 | Harry Ostrer | Genomic signatures of metastasis in prostate cancer |
| ITPD20110201A1 (it) * | 2011-06-16 | 2012-12-17 | Univ Degli Studi Trieste | Metodo per la prognosi di tumori al seno basata sull'espressione dell'enzima prolil isomerarasi pin1 in combinazione con mutazioni del gene tp53 |
| GB201116131D0 (en) * | 2011-09-19 | 2011-11-02 | Epistem Ltd | Probe |
| US20140315844A1 (en) * | 2012-11-30 | 2014-10-23 | Celera Corporation | Multi-gene signatures for predicting response to chemotherapy or risk of metastasis for breast cancer |
| KR101672531B1 (ko) * | 2013-04-18 | 2016-11-17 | 주식회사 젠큐릭스 | 조기 유방암 예후 예측 진단용 유전자 마커 및 이의 용도 |
| AU2015300970A1 (en) | 2014-08-07 | 2017-03-30 | Curelator, Inc. | Chronic disease discovery and management system |
| TWI582240B (zh) * | 2015-05-19 | 2017-05-11 | 鄭鴻鈞 | 以基因體預後評估試劑組預測乳癌患者局部區域復發風險及放射治療有效性的方法、用途及裝置 |
| WO2017047102A1 (en) * | 2015-09-16 | 2017-03-23 | Riken | Biomarker for cancer and use thereof |
| CN108647493B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 一种肾透明细胞癌个性化预后评估方法 |
| CN108470111B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的胃癌个性化预后评估方法 |
| WO2021205828A1 (ja) * | 2020-04-10 | 2021-10-14 | 国立大学法人 東京大学 | 予後予測装置、及びプログラム |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| FR2540122B1 (fr) | 1983-01-27 | 1985-11-29 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5004565A (en) | 1986-07-17 | 1991-04-02 | The Board Of Governors Of Wayne State University | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes |
| US5856522A (en) | 1995-05-04 | 1999-01-05 | Tropix, Inc. | Method of using synthesis of 1,2-dioxetanes and kits therefore |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5994073A (en) | 1990-08-30 | 1999-11-30 | Tropix, Inc. | Enhancement of chemiluminescent assays |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| US5837832A (en) | 1993-06-25 | 1998-11-17 | Affymetrix, Inc. | Arrays of nucleic acid probes on biological chips |
| US6027923A (en) | 1993-07-23 | 2000-02-22 | Bio-Rad Laboratories, Inc. | Linked linear amplification of nucleic acids |
| AU8126694A (en) | 1993-10-26 | 1995-05-22 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US6015880A (en) | 1994-03-16 | 2000-01-18 | California Institute Of Technology | Method and substrate for performing multiple sequential reactions on a matrix |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5705333A (en) | 1994-08-05 | 1998-01-06 | The Regents Of The University Of California | Peptide-based nucleic acid mimics(PENAMS) |
| US5773628A (en) | 1994-11-14 | 1998-06-30 | Tropix, Inc. | 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use |
| US5591591A (en) | 1995-02-09 | 1997-01-07 | Tropix, Inc. | Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore |
| US5801115A (en) | 1995-09-05 | 1998-09-01 | Kataleuna Gmbh | Catalyst composition and methods for using and preparing same |
| US5679803A (en) | 1995-10-25 | 1997-10-21 | Tropix, Inc. | 1,2 chemiluminescent dioxetanes of improved performance |
| US5866336A (en) | 1996-07-16 | 1999-02-02 | Oncor, Inc. | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6117635A (en) | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US5800999A (en) | 1996-12-16 | 1998-09-01 | Tropix, Inc. | Dioxetane-precursor-labeled probes and detection assays employing the same |
| WO2002072889A2 (en) | 2001-01-12 | 2002-09-19 | Applera Corporation | Methods and compositions for microarray control |
| US7306910B2 (en) * | 2003-04-24 | 2007-12-11 | Veridex, Llc | Breast cancer prognostics |
| US20050221398A1 (en) | 2004-01-16 | 2005-10-06 | Ipsogen, Sas, A Corporation Of France | Protein expression profiling and breast cancer prognosis |
| KR101515821B1 (ko) * | 2005-09-01 | 2015-04-30 | 오스다이어그나스틱스 피티와이 엘티디. | 핵산의 증폭, 정량분석 및 동정 방법 |
-
2008
- 2008-01-31 EP EP12169115.8A patent/EP2520668B1/en active Active
- 2008-01-31 WO PCT/US2008/001339 patent/WO2008094678A2/en not_active Ceased
- 2008-01-31 JP JP2009548313A patent/JP5913785B2/ja active Active
- 2008-01-31 EP EP08725050A patent/EP2129789B1/en active Active
- 2008-01-31 US US12/012,530 patent/US7695915B2/en active Active
- 2008-01-31 CA CA2674907A patent/CA2674907C/en active Active
-
2009
- 2009-12-15 US US12/638,040 patent/US8614058B2/en active Active
-
2013
- 2013-06-13 JP JP2013124548A patent/JP2013176397A/ja not_active Withdrawn
- 2013-11-19 US US14/083,755 patent/US20140179548A1/en not_active Abandoned
-
2015
- 2015-12-04 JP JP2015237175A patent/JP2016032480A/ja not_active Withdrawn
-
2016
- 2016-02-03 US US15/014,294 patent/US20160289766A1/en not_active Abandoned
-
2018
- 2018-06-08 US US16/003,682 patent/US11028445B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2674907C (en) | 2017-04-04 |
| EP2520668B1 (en) | 2014-12-24 |
| US11028445B2 (en) | 2021-06-08 |
| US20080206769A1 (en) | 2008-08-28 |
| WO2008094678A2 (en) | 2008-08-07 |
| EP2129789B1 (en) | 2013-03-06 |
| EP2520668A1 (en) | 2012-11-07 |
| CA2674907A1 (en) | 2008-08-07 |
| EP2129789A2 (en) | 2009-12-09 |
| US20160289766A1 (en) | 2016-10-06 |
| US20140179548A1 (en) | 2014-06-26 |
| JP2010516292A (ja) | 2010-05-20 |
| WO2008094678A3 (en) | 2008-11-20 |
| JP2013176397A (ja) | 2013-09-09 |
| US8614058B2 (en) | 2013-12-24 |
| US20100323921A1 (en) | 2010-12-23 |
| JP2016032480A (ja) | 2016-03-10 |
| EP2129789A4 (en) | 2010-03-24 |
| US7695915B2 (en) | 2010-04-13 |
| US20190136326A1 (en) | 2019-05-09 |
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