JP5876885B2 - ニトロベンゾチアゾール誘導体および結核治療のためのこれらの使用 - Google Patents

ニトロベンゾチアゾール誘導体および結核治療のためのこれらの使用 Download PDF

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Publication number
JP5876885B2
JP5876885B2 JP2013539319A JP2013539319A JP5876885B2 JP 5876885 B2 JP5876885 B2 JP 5876885B2 JP 2013539319 A JP2013539319 A JP 2013539319A JP 2013539319 A JP2013539319 A JP 2013539319A JP 5876885 B2 JP5876885 B2 JP 5876885B2
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JP
Japan
Prior art keywords
benzothiazole
trifluoromethyl
nitro
carboxamide
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013539319A
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English (en)
Japanese (ja)
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JP2013542976A (ja
JP2013542976A5 (enExample
Inventor
ペレ，アラン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
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Publication of JP2013542976A5 publication Critical patent/JP2013542976A5/ja
Application granted granted Critical
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Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2013539319A 2010-11-22 2011-11-18 ニトロベンゾチアゾール誘導体および結核治療のためのこれらの使用 Expired - Fee Related JP5876885B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1059602 2010-11-22
FR1059602A FR2967672B1 (fr) 2010-11-22 2010-11-22 Derives de nitrobenzothiazoles, leur preparation et leurs applications therapeutiques
PCT/FR2011/052699 WO2012069743A1 (fr) 2010-11-22 2011-11-18 Derives de nitrobenzothiazoles et leur utilisation pour le traitment de la tubercolose

Publications (3)

Publication Number Publication Date
JP2013542976A JP2013542976A (ja) 2013-11-28
JP2013542976A5 JP2013542976A5 (enExample) 2015-10-01
JP5876885B2 true JP5876885B2 (ja) 2016-03-02

Family

ID=43498537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013539319A Expired - Fee Related JP5876885B2 (ja) 2010-11-22 2011-11-18 ニトロベンゾチアゾール誘導体および結核治療のためのこれらの使用

Country Status (5)

Country Link
US (1) US8993561B2 (enExample)
EP (1) EP2643307B1 (enExample)
JP (1) JP5876885B2 (enExample)
FR (1) FR2967672B1 (enExample)
WO (1) WO2012069743A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2688403T (pt) 2011-03-23 2017-07-13 Trevena Inc Ligandos de recetores opioides e métodos de uso e fabrico dos mesmos
CN103204825B (zh) 2012-01-17 2015-03-04 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻唑化合物及其制备方法和用途
HK1251472A1 (zh) 2015-12-14 2019-02-01 特维娜有限公司 治療痛覺過敏的方法
CN118660885A (zh) * 2022-01-06 2024-09-17 国家医疗保健研究所 降冰片烯类似物及其作为抗结核药物增效剂的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2013434A1 (en) * 1970-03-20 1971-10-07 Farbenfabriken Bayer Ag, 5090 Lever Kusen Benzothiazole 3-oxides as concrementinhibitors
BE786520A (fr) * 1971-07-23 1973-01-22 Bayer Ag Nouveaux benzothiazoles substitues, leur preparation et leur application comme fongicides et bactericides
BE786521A (fr) 1971-07-23 1973-01-22 Bayer Ag Procede de preparation de 4-chloro-benzothiazoles
RU2227458C2 (ru) 1998-06-18 2004-04-27 Новартис Аг Применение бензазольных соединений в качестве репеллента, композиция их содержащая и способ получения композиции
CA2338328A1 (en) * 1998-07-21 2000-02-03 Thomas Jefferson University Small molecule inhibitors of bcl-2 proteins
JP2000086642A (ja) 1998-09-11 2000-03-28 Kyorin Pharmaceut Co Ltd ベンゾチアゾール誘導体及びその製造法
JP2000178248A (ja) 1998-12-14 2000-06-27 Japan Tobacco Inc 免疫賦活活性を有する化合物
GB0302220D0 (en) * 2003-01-30 2003-03-05 Cyclacel Ltd Use
GB0428173D0 (en) * 2004-12-23 2005-01-26 Astrazeneca Ab Compounds

Also Published As

Publication number Publication date
JP2013542976A (ja) 2013-11-28
US20130245008A1 (en) 2013-09-19
US8993561B2 (en) 2015-03-31
FR2967672B1 (fr) 2012-12-28
EP2643307B1 (fr) 2014-09-17
WO2012069743A1 (fr) 2012-05-31
EP2643307A1 (fr) 2013-10-02
FR2967672A1 (fr) 2012-05-25

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