JP5868327B2 - 光検出装置及び方法 - Google Patents

光検出装置及び方法 Download PDF

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Publication number
JP5868327B2
JP5868327B2 JP2012539854A JP2012539854A JP5868327B2 JP 5868327 B2 JP5868327 B2 JP 5868327B2 JP 2012539854 A JP2012539854 A JP 2012539854A JP 2012539854 A JP2012539854 A JP 2012539854A JP 5868327 B2 JP5868327 B2 JP 5868327B2
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Japan
Prior art keywords
sample
fluid cell
fluid
channel
spectrometer
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JP2012539854A
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English (en)
Japanese (ja)
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JP2013511714A5 (https=
JP2013511714A (ja
Inventor
山田雅子
マレー，アンソニー・ジェイ
ジュー，チャルミン
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General Electric Co
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General Electric Co
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Publication of JP2013511714A5 publication Critical patent/JP2013511714A5/ja
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2012539854A 2009-11-23 2010-11-22 光検出装置及び方法 Active JP5868327B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/623,714 US20110122412A1 (en) 2009-11-23 2009-11-23 Devices and methods for optical detection
US12/623,714 2009-11-23
PCT/SE2010/051281 WO2011062555A1 (en) 2009-11-23 2010-11-22 Devices and methods for optical detection

Publications (3)

Publication Number Publication Date
JP2013511714A JP2013511714A (ja) 2013-04-04
JP2013511714A5 JP2013511714A5 (https=) 2015-04-09
JP5868327B2 true JP5868327B2 (ja) 2016-02-24

Family

ID=44059849

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012539854A Active JP5868327B2 (ja) 2009-11-23 2010-11-22 光検出装置及び方法

Country Status (4)

Country Link
US (1) US20110122412A1 (https=)
EP (1) EP2504686A4 (https=)
JP (1) JP5868327B2 (https=)
WO (1) WO2011062555A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6134719B2 (ja) * 2011-09-30 2017-05-24 ゼネラル・エレクトリック・カンパニイ 試料配列の自己対照型検出及び撮像のためのシステム及び方法
US9778166B2 (en) 2014-02-24 2017-10-03 National University Corporation Kagawa University Microparticle measurement device
EP3247988A4 (en) * 2015-01-23 2018-12-19 Vanderbilt University A robust interferometer and methods of using same
WO2017074855A1 (en) * 2015-10-26 2017-05-04 Entegris, Inc. Index of refraction sensor system with dual mode temperature control
US20220113244A1 (en) * 2019-02-12 2022-04-14 Christoph Langhammer System and method for detecting a presence of a particle in a fluid
CN115825028B (zh) * 2022-11-27 2025-07-25 云南大学 一种可用于多离子同时检测的光纤光流控检测系统和检测方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034774A (en) * 1998-06-26 2000-03-07 Eastman Kodak Company Method for determining the retardation of a material using non-coherent light interferometery
RU2181487C2 (ru) * 2000-05-11 2002-04-20 Никитин Петр Иванович Способ оптического детектирования присоединения вещественного компонента к сенсорному материалу на основе биологического, химического или физического взаимодействия и устройство для его осуществления (варианты)
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US6809828B2 (en) * 2001-01-25 2004-10-26 Texas Tech University Universal detector for biological and chemical separations or assays using plastic microfluidic devices
US7517656B2 (en) * 2002-07-30 2009-04-14 Trex Enterprises Corp. Optical sensor and methods for measuring molecular binding interactions
US20060063178A1 (en) * 2002-06-27 2006-03-23 Trex Enterprises Corporation Optical sensor and methods for measuring molecular binding interactions
AU2003295805A1 (en) * 2002-11-22 2004-06-18 Solus Biosystems, Inc. High throughput screening with parallel vibrational spectroscopy
GB2406638B (en) * 2003-10-01 2006-03-29 Amc Amsterdam Interferometric measurement apparatus and method therefor
US7394547B2 (en) * 2003-11-06 2008-07-01 Fortebio, Inc. Fiber-optic assay apparatus based on phase-shift interferometry
US20070108465A1 (en) * 2005-03-10 2007-05-17 The Regents Of The University Of California Porous microstructure multi layer spectroscopy and biosensing
WO2006124860A1 (en) * 2005-05-13 2006-11-23 The General Hospital Corporation Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample
JP4920373B2 (ja) * 2006-11-08 2012-04-18 日本電信電話株式会社 屈折率変化の測定装置
US7835013B2 (en) * 2007-05-18 2010-11-16 Vanderbilt University Interferometric detection system and method
WO2009073259A2 (en) * 2007-09-14 2009-06-11 University Of Rochester Common-path interferometer rendering amplitude and phase of scattered light
US8599383B2 (en) * 2009-05-06 2013-12-03 The Regents Of The University Of California Optical cytometry

Also Published As

Publication number Publication date
EP2504686A4 (en) 2018-01-03
US20110122412A1 (en) 2011-05-26
EP2504686A1 (en) 2012-10-03
JP2013511714A (ja) 2013-04-04
WO2011062555A1 (en) 2011-05-26

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