JP5836262B2 - サイクリックampエンハンサーおよび/またはepリガンドを含む組成物、ならびにこれを調製および使用する方法 - Google Patents
サイクリックampエンハンサーおよび/またはepリガンドを含む組成物、ならびにこれを調製および使用する方法 Download PDFInfo
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- JP5836262B2 JP5836262B2 JP2012500968A JP2012500968A JP5836262B2 JP 5836262 B2 JP5836262 B2 JP 5836262B2 JP 2012500968 A JP2012500968 A JP 2012500968A JP 2012500968 A JP2012500968 A JP 2012500968A JP 5836262 B2 JP5836262 B2 JP 5836262B2
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- A61P35/00—Antineoplastic agents
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US61/248,765 | 2009-10-05 | ||
| PCT/US2010/027852 WO2010108028A2 (en) | 2009-03-19 | 2010-03-18 | Compositions comprising cyclic amp enhancers and/or ep ligands, and methods of preparing and using the same |
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| JP2018177292A Withdrawn JP2018199724A (ja) | 2009-03-19 | 2018-09-21 | サイクリックampエンハンサーおよび/またはepリガンドを含む組成物、ならびにこれを調製および使用する方法 |
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| JP2017047351A Withdrawn JP2017105840A (ja) | 2009-03-19 | 2017-03-13 | サイクリックampエンハンサーおよび/またはepリガンドを含む組成物、ならびにこれを調製および使用する方法 |
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| CN108379292A (zh) | 2008-11-06 | 2018-08-10 | 印第安纳大学研究与技术公司 | 增强造血干细胞植入过程的材料和方法 |
| WO2010108028A2 (en) * | 2009-03-19 | 2010-09-23 | Fate Therapeutics, Inc. | Compositions comprising cyclic amp enhancers and/or ep ligands, and methods of preparing and using the same |
| US11459545B2 (en) | 2009-11-15 | 2022-10-04 | Indiana University Research And Technology Corporation | Methods to enhance delivery and engraftment of stem cells including the identification of specific prostaglandin E2 receptors |
| US10213464B2 (en) * | 2011-01-13 | 2019-02-26 | Scipharm Sarl | Method for enhancing engraftment of haematopoetic stem cells |
| ES2769270T3 (es) | 2011-09-30 | 2020-06-25 | Bluebird Bio Inc | Compuestos para transducción viral mejorada |
| JP6220791B2 (ja) | 2011-12-02 | 2017-10-25 | フェイト セラピューティクス,インコーポレイテッド | 増強された幹細胞組成物 |
| EP2785350B1 (en) | 2011-12-02 | 2018-05-02 | Fate Therapeutics, Inc. | Improved methods of treating ischemia |
| WO2014150602A1 (en) | 2013-03-15 | 2014-09-25 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
| US9943545B2 (en) * | 2013-03-15 | 2018-04-17 | Fate Therapeutics, Inc. | Stem cell culture media and methods of enhancing cell survival |
| WO2014153363A1 (en) * | 2013-03-18 | 2014-09-25 | Northeastern University | Method for generation of broadly neutralizing anti-pathogen antibodies |
| AU2014305843B2 (en) | 2013-08-09 | 2019-08-29 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| CN104614455B (zh) * | 2014-12-25 | 2016-10-05 | 上海景峰制药有限公司 | 一种前列地尔注射液的含量检测方法 |
| US20180112180A1 (en) | 2015-01-26 | 2018-04-26 | Fate Therapeutics, Inc. | Cells with increased immuno-regulatory properties and methods for their use and manufacture |
| US20180214487A1 (en) | 2015-07-21 | 2018-08-02 | The Children's Medical Center Corporation | Pd-l1 expressing hematopoietic stem cells and uses |
| IL261002B2 (en) | 2016-02-12 | 2024-07-01 | Bluebird Bio Inc | Vcn enhancer compositions and methods of using the same |
| WO2017139561A1 (en) | 2016-02-12 | 2017-08-17 | Bluebird Bio, Inc. | Vcn enhancer compositions and methods of using the same |
| US11879137B2 (en) | 2017-09-22 | 2024-01-23 | The Children's Medical Center Corporation | Treatment of type 1 diabetes and autoimmune diseases or disorders |
| EP4706758A3 (en) | 2019-05-21 | 2026-05-06 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
| EP4146797A1 (en) | 2020-05-06 | 2023-03-15 | Orchard Therapeutics (Europe) Limited | Treatment for neurodegenerative diseases |
| CN114854674B (zh) * | 2022-06-20 | 2025-01-24 | 中国农业大学 | dbcAMP在制备原始卵泡体外激活剂中的应用 |
| CN115636776B (zh) * | 2022-10-10 | 2024-05-07 | 厦门欧瑞捷生物科技有限公司 | 一种以PGF2α合成中的副产物为原料合成前列地尔的方法 |
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| BE790840A (fr) * | 1971-11-01 | 1973-04-30 | Upjohn Co | Solutions de medicaments instables et leur preparation |
| US5004681B1 (en) * | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| US5753516A (en) * | 1995-02-03 | 1998-05-19 | Heagy; Wyrta E. | Screening method for ligands of the EBI-1 receptor |
| US6440734B1 (en) * | 1998-09-25 | 2002-08-27 | Cytomatrix, Llc | Methods and devices for the long-term culture of hematopoietic progenitor cells |
| AU2183900A (en) | 1998-12-24 | 2000-07-31 | Alcon Laboratories, Inc. | Ep4 receptor agonists for treatment of dry eye |
| HK1048302A1 (zh) | 1999-08-13 | 2003-03-28 | 大正制药株式会社 | 前列腺素衍生物 |
| DE60120007T2 (de) | 2000-01-31 | 2006-11-16 | Pfizer Products Inc., Groton | Verwendung von Aktivatoren des Prostaglandinrezeptores 4 zur Behandlung von akuter oder chronischer Niereninsuffizienz |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| FR2825261B1 (fr) | 2001-06-01 | 2003-09-12 | Maco Pharma Sa | Ligne de prelevement du sang placentaire comprenant une poche de rincage |
| US7179643B2 (en) * | 2001-06-14 | 2007-02-20 | Reliance Life Sciences Pvt. Ltd. | Device and a process for expansion of haemopoeitic stem cells for therapeutic use |
| JP2003093048A (ja) * | 2001-09-26 | 2003-04-02 | Asahi Kasei Corp | 新規細胞製剤製造用培養媒体 |
| US6747037B1 (en) | 2003-06-06 | 2004-06-08 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| US20050032122A1 (en) * | 2003-08-06 | 2005-02-10 | Shiaw-Min Hwang | Optimizing culture medium for CD34<+> hematopoietic cell expansion |
| GB0329620D0 (en) | 2003-12-22 | 2004-01-28 | Pharmagene Lab Ltd | EP2 receptor agonists |
| WO2005065396A2 (en) * | 2003-12-31 | 2005-07-21 | Osteotech, Inc. | Improved bone matrix compositions and methods |
| US7147626B2 (en) | 2004-09-23 | 2006-12-12 | Celgene Corporation | Cord blood and placenta collection kit |
| JP2008518013A (ja) | 2004-10-26 | 2008-05-29 | アラーガン、インコーポレイテッド | プロスタグランジンep4アゴニストによる処置方法およびデリバリー方法 |
| DE102005062741A1 (de) | 2005-12-22 | 2007-06-28 | Bayer Schering Pharma Ag | Fluorene und Carbazole als Liganden des EP2 Rezeptors |
| RU2425876C2 (ru) * | 2006-03-24 | 2011-08-10 | Чилдрен'З Медикал Сентер Корпорейшн | Способ модулирования роста гематопоэтических стволовых клеток |
| EP2094839B1 (en) * | 2006-12-08 | 2020-02-05 | University of Rochester | Expansion of hematopoietic stem cells |
| US8871752B2 (en) * | 2008-02-19 | 2014-10-28 | Sucampo Ag | Method for modulating stem cell growth |
| WO2010108028A2 (en) * | 2009-03-19 | 2010-09-23 | Fate Therapeutics, Inc. | Compositions comprising cyclic amp enhancers and/or ep ligands, and methods of preparing and using the same |
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2010
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- 2010-03-18 JP JP2012500968A patent/JP5836262B2/ja not_active Expired - Fee Related
- 2010-03-18 EP EP10754130A patent/EP2408444A4/en not_active Withdrawn
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2015
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2017
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2018
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| WO2010108028A2 (en) | 2010-09-23 |
| US20120202288A1 (en) | 2012-08-09 |
| EP2408444A4 (en) | 2012-09-26 |
| JP2017105840A (ja) | 2017-06-15 |
| JP2012521349A (ja) | 2012-09-13 |
| JP2018199724A (ja) | 2018-12-20 |
| WO2010108028A3 (en) | 2011-03-31 |
| JP6177273B2 (ja) | 2017-08-09 |
| EP3533445A1 (en) | 2019-09-04 |
| JP2020186273A (ja) | 2020-11-19 |
| JP2015180645A (ja) | 2015-10-15 |
| EP2408444A2 (en) | 2012-01-25 |
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