JP5802198B2 - 経口投与のための新規の光増感剤製剤 - Google Patents

経口投与のための新規の光増感剤製剤 Download PDF

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JP5802198B2
JP5802198B2 JP2012508649A JP2012508649A JP5802198B2 JP 5802198 B2 JP5802198 B2 JP 5802198B2 JP 2012508649 A JP2012508649 A JP 2012508649A JP 2012508649 A JP2012508649 A JP 2012508649A JP 5802198 B2 JP5802198 B2 JP 5802198B2
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photosensitizer
oral
time
period
treatment
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Japanese (ja)
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JP2012525411A (ja
JP2012525411A5 (OSRAM
Inventor
ファルマー，ゲラルド
ニファンティエフ，ニコライ
アルブレヒト，フォルカー
ノイベルガー，ウォルフガング
シェグルマン，ダイエットリッチ
ゲルハルト，ヴィーラント
ヴィーエ，アルノ
グレーフェ，スザンナ
Original Assignee
セラムオプテック ゲーエムベーハー
セラムオプテック ゲーエムベーハー
バイオリテック リサーチ ゲーエムベーハー
バイオリテック リサーチ ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012508649A 2009-04-28 2010-04-28 経口投与のための新規の光増感剤製剤 Expired - Fee Related JP5802198B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17347709P 2009-04-28 2009-04-28
US61/173,477 2009-04-28
PCT/US2010/032780 WO2010129340A2 (en) 2009-04-28 2010-04-28 Novel photosensitizer formulations for oral administration

Publications (3)

Publication Number Publication Date
JP2012525411A JP2012525411A (ja) 2012-10-22
JP2012525411A5 JP2012525411A5 (OSRAM) 2014-01-23
JP5802198B2 true JP5802198B2 (ja) 2015-10-28

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ID=43050758

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JP2012508649A Expired - Fee Related JP5802198B2 (ja) 2009-04-28 2010-04-28 経口投与のための新規の光増感剤製剤

Country Status (5)

Country Link
US (1) US20120101427A1 (OSRAM)
EP (1) EP2424536A4 (OSRAM)
JP (1) JP5802198B2 (OSRAM)
CN (1) CN102695509A (OSRAM)
WO (1) WO2010129340A2 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015183346A2 (en) * 2014-01-31 2015-12-03 Washington University Imaging and treatment of pathophysiologic conditions by cerenkov radiation
US9974870B2 (en) 2014-06-09 2018-05-22 Washington University Compositions and methods for treatment and imaging using nanoparticles
EP3201201B1 (en) 2014-09-30 2022-01-26 biolitec unternehmensbeteiligungs II AG Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
ES3011714T3 (en) 2016-02-26 2025-04-08 Biolitec Holding Gmbh & Co Kg Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy
PT3225112T (pt) * 2016-04-01 2021-09-16 Trioptotec Gmbh Dispersão de fotossensibilizador e utilização da mesma
EP3894421A1 (en) 2018-12-10 2021-10-20 Universität Hamburg Specifically glyco-substituted porphyrins and chlorins for photodynamic therapy
FR3100247B1 (fr) * 2019-09-02 2021-08-06 Centre Nat Rech Scient Dérivé de phénazine et ses utilisations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223494A (en) * 1989-09-25 1993-06-29 The Rockefeller University Orally administered porphyrins to control intestinal iron absorption
US5514669A (en) * 1993-09-29 1996-05-07 Medical College Of Ohio Use of photodynamic therapy to treat prostatic tissue
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
AU2789900A (en) * 1999-02-26 2000-09-21 Qlt Phototherapeutics, Inc. Photodynamic therapy in combination with apoptosis inducing factors
CA2408332C (en) * 2000-05-08 2011-02-15 The University Of British Columbia Supports for photosensitizer formulations
US6558653B2 (en) * 2001-09-19 2003-05-06 Scot N. Andersen Methods for treating periodontal disease
JP2005514346A (ja) * 2001-11-09 2005-05-19 キュー エル ティー インク． 光感作剤及び皮膚浸透エンハンサーを含有する組成物並びに光力学療法におけるそれらの使用
US20040077621A1 (en) * 2002-08-08 2004-04-22 Academia Sinica Antioxidants
US20050049228A1 (en) * 2003-09-02 2005-03-03 Ceramoptec Industries Inc. Antimicrobial photodynamic therapy compound and method of use
US20080317850A1 (en) * 2005-04-08 2008-12-25 Ernest Alan Hewitt Buccal Delivery System
US20060264423A1 (en) * 2005-05-20 2006-11-23 Bioenvision, Inc. Methylene Blue Therapy of Viral Disease
EP1906947A4 (en) * 2005-06-13 2012-11-14 Univ Singapore LIGHT-SENSITIVE COMPOSITION AND ITS USES
WO2007144048A2 (en) * 2006-06-12 2007-12-21 Dsm Fine Chemicals Austria Nfg Gmbh & Co. Kg Presentation form for the oral administration of phenothiazine dyes, its production and use
US20070299046A1 (en) * 2006-06-26 2007-12-27 Mai Nguyen Brooks Orally available light-independent antineoplastic compounds
WO2008052350A1 (en) * 2006-11-03 2008-05-08 Qlt Inc. Photodynamic therapy for the treatment of hidradenitis suppurativa

Also Published As

Publication number Publication date
EP2424536A2 (en) 2012-03-07
EP2424536A4 (en) 2012-10-31
WO2010129340A3 (en) 2011-04-07
JP2012525411A (ja) 2012-10-22
CN102695509A (zh) 2012-09-26
WO2010129340A2 (en) 2010-11-11
US20120101427A1 (en) 2012-04-26

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