JP5798124B2 - ワクチン構築物におけるポックスウイルスエレメントに関する免疫原性組成物 - Google Patents

ワクチン構築物におけるポックスウイルスエレメントに関する免疫原性組成物 Download PDF

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JP5798124B2
JP5798124B2 JP2012540139A JP2012540139A JP5798124B2 JP 5798124 B2 JP5798124 B2 JP 5798124B2 JP 2012540139 A JP2012540139 A JP 2012540139A JP 2012540139 A JP2012540139 A JP 2012540139A JP 5798124 B2 JP5798124 B2 JP 5798124B2
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poxvirus
influenza
virus
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JP2013511552A (ja
JP2013511552A5 (enExample
Inventor
ダン ティー. スティンチコブ,
ダン ティー. スティンチコブ,
ジョージ イー. オソリオ,
ジョージ イー. オソリオ,
ティモシー ディー. パウエル,
ティモシー ディー. パウエル,
ジェレミー ジョーンズ,
ジェレミー ジョーンズ,
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Takeda Vaccines Inc
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Takeda Vaccines Inc
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/863Poxviral vectors, e.g. entomopoxvirus
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
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    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
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    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
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    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012540139A 2009-11-20 2010-11-22 ワクチン構築物におけるポックスウイルスエレメントに関する免疫原性組成物 Expired - Fee Related JP5798124B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26332709P 2009-11-20 2009-11-20
US61/263,327 2009-11-20
PCT/US2010/057682 WO2011063359A1 (en) 2009-11-20 2010-11-22 Compositions, methods and uses for poxvirus elements in vaccine constructs

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JP2013511552A JP2013511552A (ja) 2013-04-04
JP2013511552A5 JP2013511552A5 (enExample) 2014-01-16
JP5798124B2 true JP5798124B2 (ja) 2015-10-21

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JP2012540139A Expired - Fee Related JP5798124B2 (ja) 2009-11-20 2010-11-22 ワクチン構築物におけるポックスウイルスエレメントに関する免疫原性組成物

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US (2) US9011874B2 (enExample)
EP (1) EP2501405A4 (enExample)
JP (1) JP5798124B2 (enExample)
AU (1) AU2010321731B2 (enExample)
CA (1) CA2781397A1 (enExample)
WO (1) WO2011063359A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9005632B2 (en) * 2009-11-20 2015-04-14 Takeda Vaccines, Inc. Compositions, methods and uses for poxvirus elements in vaccine constructs against influenza virus subtypes or strains
EP3197490B1 (en) * 2014-09-26 2023-06-21 Bavarian Nordic A/S Methods and compositions for intra-nasal immunization with recombinant mva encoding flagellin

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA68327C2 (en) 1995-07-04 2004-08-16 Gsf Forschungszentrum Fur Unwe A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals
WO1997027216A1 (en) * 1996-01-29 1997-07-31 Georgetown University Amplification of response from expressed recombinant protein
NZ521270A (en) * 2000-03-14 2003-06-30 Bavarian Nordic As Altered strain of the Modified Vaccinia virus Ankara (MVA) for growth in a continuous vero cell line
DE20122302U1 (de) * 2000-11-23 2005-02-24 Bavarian Nordic A/S Variante des Modifizierten Vaccinia-Ankara-Virus
AU2003258168B2 (en) * 2002-08-12 2009-10-29 Sillajen Biotherapeutics, Inc. Methods and compositions concerning poxviruses and cancer
EP1928916A2 (en) * 2005-09-29 2008-06-11 Viral Logic Systems Technology Corp. Immunomodulatory compositions and uses therefor
CA2657849A1 (en) * 2006-05-18 2008-05-08 Pharmexa Inc. Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions
US7910112B2 (en) * 2006-11-06 2011-03-22 Merial Limited Feline vaccines against avian influenza
EP1925318A1 (en) 2006-11-20 2008-05-28 Paul-Ehrlich-Institut Recombinant modified vaccinia virus Ankara (MVA)-based vaccine for the avian flu
EP2167123A4 (en) * 2007-07-09 2012-09-05 Usa As Represented By The Secretary Of The Army On Behalf Of The United States Army Medical Res COMPOSITIONS CONTAINING L1R ENUCTIVE NUCLEIC ACID AND ENDOPLASMIC RETICULUM TARGETING SEQUENCE
US7807180B2 (en) * 2007-08-21 2010-10-05 University Of Massachusetts Poxvirus methods and compositions

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AU2010321731B2 (en) 2017-01-05
WO2011063359A1 (en) 2011-05-26
JP2013511552A (ja) 2013-04-04
AU2010321731A1 (en) 2012-07-12
US20130136767A1 (en) 2013-05-30
EP2501405A4 (en) 2013-12-04
US20150184198A1 (en) 2015-07-02
US9011874B2 (en) 2015-04-21
EP2501405A1 (en) 2012-09-26
CA2781397A1 (en) 2011-05-26

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