JP5788178B2 - ウィルス感染症の治療のための組成物及び方法 - Google Patents
ウィルス感染症の治療のための組成物及び方法 Download PDFInfo
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- JP5788178B2 JP5788178B2 JP2010544340A JP2010544340A JP5788178B2 JP 5788178 B2 JP5788178 B2 JP 5788178B2 JP 2010544340 A JP2010544340 A JP 2010544340A JP 2010544340 A JP2010544340 A JP 2010544340A JP 5788178 B2 JP5788178 B2 JP 5788178B2
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| PCT/US2009/000438 WO2009108261A2 (en) | 2008-01-23 | 2009-01-23 | Compositions and methods for the treatment of viral infections |
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| AU2007307254A1 (en) * | 2006-10-05 | 2008-04-17 | New York Blood Center, Inc. | Stabilized therapeutic small helical antiviral peptides |
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| WO2009110952A2 (en) | 2007-12-31 | 2009-09-11 | New York University | Control of viral-host membrane fusion with hydrogen bond surrogate-based artificial helices |
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| CA2725227A1 (en) | 2008-05-06 | 2009-11-12 | Asim Kumar Debnath | Antiviral cell penetrating peptides |
| ES2666458T3 (es) | 2008-09-22 | 2018-05-04 | Aileron Therapeutics, Inc. | Macrociclos peptidomiméticos |
| EP2352507A4 (en) | 2008-11-24 | 2012-04-25 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES WITH IMPROVED PROPERTIES |
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| US9029332B2 (en) | 2010-12-15 | 2015-05-12 | The Research Foundation For The State University Of New York | Cross-linked peptides and proteins, methods of making same, and uses thereof |
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| CA2862391C (en) * | 2011-12-29 | 2023-10-10 | Loren D. Walensky | Stabilized antiviral fusion helices |
| BR112014022958A2 (pt) * | 2012-03-20 | 2017-07-18 | Merck Sharp & Dohme | peptídeo mimético de gp41, composição imunogênica, e, método para obter uma resposta imune em um hospedeiro mamífero |
| CN103483428B (zh) * | 2012-06-11 | 2017-05-17 | 中国人民解放军军事医学科学院毒物药物研究所 | 抑制hiv感染的小分子‑多肽缀合物 |
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| JP7069126B2 (ja) | 2016-08-26 | 2022-05-17 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 化学療法誘発性末梢性ニューロパシーおよび難聴を処置または予防するためのbcl-wポリペプチドおよび模倣物 |
| EP3551213A4 (en) | 2016-12-07 | 2020-11-04 | The University of Chicago | FOX3 INHIBITION COMPOSITIONS AND METHODS |
| JP7305614B2 (ja) | 2017-07-19 | 2023-07-10 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 抗生物質耐性細菌感染症の処置のための安定化抗菌ペプチド |
| EA202090513A1 (ru) | 2017-09-07 | 2020-08-24 | Фог Фармасьютикалз, Инк. | Агенты, модулирующие функции бета-катенина, и связанные способы |
| WO2019090015A1 (en) | 2017-11-03 | 2019-05-09 | Yale University | Peptidic materials that traffic efficiently to the cell cytosol and nucleus |
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| CN108822190B (zh) * | 2018-05-23 | 2021-11-09 | 中国人民解放军军事科学院军事医学研究院 | 多肽及其药物组合物和用途 |
| EP3840766A4 (en) | 2018-08-20 | 2022-06-22 | Fog Pharmaceuticals, Inc. | Collections of peptides, peptide agents, and methods of use thereof |
| CA3173973A1 (en) * | 2020-03-04 | 2021-09-10 | Dana-Farber Cancer Institute, Inc. | Antiviral structurally-stabilized sars-cov-2 peptides and uses thereof |
| WO2021183463A1 (en) * | 2020-03-09 | 2021-09-16 | President And Fellows Of Harvard College | Compositions and methods for treating coronavirus |
| WO2021207517A2 (en) * | 2020-04-10 | 2021-10-14 | Sapience Therapeutics, Inc. | Modified hr2 peptide inhibitors of coronavirus fusion |
| AU2021258205A1 (en) * | 2020-04-22 | 2022-10-13 | Dana-Farber Cancer Institute, Inc. | Antiviral structurally-stabilized ACE2 helix 1 peptides and uses thereof |
| AU2021360898A1 (en) * | 2020-10-14 | 2023-03-23 | Dana-Farber Cancer Institute, Inc. | Chimeric conjugates for degradation of viral and host proteins and methods of use |
| US20240226304A1 (en) * | 2020-10-14 | 2024-07-11 | The Trustees Of Columbia University In The City Of New York | Lipopeptide fusion inhibitors as sars-cov-2 antivirals |
| US11479582B2 (en) | 2020-10-16 | 2022-10-25 | King Faisal University | Anti-SARS-CoV-2 fusion peptides |
| WO2022098848A1 (en) * | 2020-11-05 | 2022-05-12 | Dana-Farber Cancer Institute, Inc. | Antiviral structurally-stabilized ebolavirus peptides and uses thereof |
| US20240052330A1 (en) * | 2020-12-22 | 2024-02-15 | The University Of Chicago | Blockade of sars-cov-2 infection using hydrocarbon stapled peptides |
| EP4453245A4 (en) * | 2021-12-23 | 2025-12-31 | Mammoth Biosciences Inc | DOSING IMPROVEMENTS BASED ON A PROGRAMMABLE NUCLEASE |
| WO2026024936A2 (en) | 2024-07-25 | 2026-01-29 | Dana-Farber Cancer Institute, Inc. | Bh4 domain peptides and uses thereof |
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| EP0938497B1 (en) | 1996-11-06 | 2007-02-28 | Genentech, Inc. | Constrained helical peptides and methods of making same |
| US6271198B1 (en) | 1996-11-06 | 2001-08-07 | Genentech, Inc. | Constrained helical peptides and methods of making same |
| JP2003529319A (ja) * | 1999-01-08 | 2003-10-07 | キャロル ディ. ウエイス, | HIV−1gp41を標的化する広範に中和する抗体を誘発する方法 |
| US20060241027A1 (en) * | 2002-02-07 | 2006-10-26 | Hans-Peter Hauser | Hiv inhibiting proteins |
| WO2005034842A2 (en) * | 2003-05-19 | 2005-04-21 | Progenics Pharmaceuticals, Inc. | Peptides useful as hiv fusion inhibitors |
| EP1997828B1 (en) * | 2003-11-05 | 2017-10-04 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides from BCL-2 and uses thereof |
| BRPI0418304A (pt) | 2004-01-07 | 2007-05-02 | Trimeris Inc | peptìdeo sintético, uso do mesmo, composição farmacêutica, seqüência de nucleotìdeos, e, métodos para inibição da transmissão de hiv para uma célula, para inibição da fusão de hiv, e para tratamento de um indivìduo infectado com hiv |
| WO2006121809A2 (en) * | 2005-05-06 | 2006-11-16 | Albert Einstein College Of Medicine Of Yeshiva University | Inhibition of membrane fusion proteins |
| JP5783721B2 (ja) * | 2007-09-26 | 2015-09-24 | ダナ ファーバー キャンサー インスティテュート インコーポレイテッド | Bcl−2ファミリーポリペプチドを調節する方法及び組成物 |
| EP2205256A4 (en) | 2007-09-26 | 2012-10-24 | Dana Farber Cancer Inst Inc | REAGENTS TO TRIGGER IMMUNE REACTION |
| JP5788178B2 (ja) | 2008-01-23 | 2015-09-30 | ダナ ファーバー キャンサー インスティテュート インコーポレイテッド | ウィルス感染症の治療のための組成物及び方法 |
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| WO2009108261A2 (en) | 2009-09-03 |
| CA2713089C (en) | 2017-11-21 |
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| US9290545B2 (en) | 2016-03-22 |
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| EP2247606A2 (en) | 2010-11-10 |
| US20160152667A1 (en) | 2016-06-02 |
| US10259848B2 (en) | 2019-04-16 |
| CA2713089A1 (en) | 2009-09-03 |
| EP2247606B1 (en) | 2019-08-21 |
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