JP5777340B2 - Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ - Google Patents
Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ Download PDFInfo
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- JP5777340B2 JP5777340B2 JP2010520284A JP2010520284A JP5777340B2 JP 5777340 B2 JP5777340 B2 JP 5777340B2 JP 2010520284 A JP2010520284 A JP 2010520284A JP 2010520284 A JP2010520284 A JP 2010520284A JP 5777340 B2 JP5777340 B2 JP 5777340B2
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- nucleotide
- primer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95429007P | 2007-08-06 | 2007-08-06 | |
| US60/954,290 | 2007-08-06 | ||
| US98871507P | 2007-11-16 | 2007-11-16 | |
| US60/988,715 | 2007-11-16 | ||
| PCT/US2008/072356 WO2009021054A2 (en) | 2007-08-06 | 2008-08-06 | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015070799A Division JP5902843B2 (ja) | 2007-08-06 | 2015-03-31 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010535507A JP2010535507A (ja) | 2010-11-25 |
| JP2010535507A5 JP2010535507A5 (enExample) | 2011-09-22 |
| JP5777340B2 true JP5777340B2 (ja) | 2015-09-09 |
Family
ID=39925054
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520284A Expired - Fee Related JP5777340B2 (ja) | 2007-08-06 | 2008-08-06 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
| JP2015070799A Expired - Fee Related JP5902843B2 (ja) | 2007-08-06 | 2015-03-31 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
| JP2016046545A Pending JP2016116534A (ja) | 2007-08-06 | 2016-03-10 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015070799A Expired - Fee Related JP5902843B2 (ja) | 2007-08-06 | 2015-03-31 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
| JP2016046545A Pending JP2016116534A (ja) | 2007-08-06 | 2016-03-10 | Igf2遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ |
Country Status (7)
| Country | Link |
|---|---|
| US (7) | US8420315B2 (enExample) |
| EP (3) | EP2185726B1 (enExample) |
| JP (3) | JP5777340B2 (enExample) |
| AU (1) | AU2008283902B2 (enExample) |
| CA (1) | CA2694832A1 (enExample) |
| ES (2) | ES2453108T3 (enExample) |
| WO (1) | WO2009021054A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11001881B2 (en) | 2006-08-24 | 2021-05-11 | California Institute Of Technology | Methods for detecting analytes |
| US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
| US8048626B2 (en) | 2006-07-28 | 2011-11-01 | California Institute Of Technology | Multiplex Q-PCR arrays |
| US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| ES2453108T3 (es) | 2007-08-06 | 2014-04-04 | Orion Genomics, Llc | Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2 |
| CN103396487A (zh) | 2008-12-12 | 2013-11-20 | 贝林格尔.英格海姆国际有限公司 | 抗igf抗体 |
| CA2751758A1 (en) * | 2009-02-11 | 2010-08-19 | Orion Genomics Llc | Combinations of polymorphisms for determining allele-specific expression of igf2 |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| US9708647B2 (en) | 2015-03-23 | 2017-07-18 | Insilixa, Inc. | Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays |
| US9499861B1 (en) | 2015-09-10 | 2016-11-22 | Insilixa, Inc. | Methods and systems for multiplex quantitative nucleic acid amplification |
| WO2017155858A1 (en) | 2016-03-07 | 2017-09-14 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
| CN119510370A (zh) | 2019-03-14 | 2025-02-25 | 因斯利克萨公司 | 基于时间门控的荧光检测的方法和系统 |
| US12222354B2 (en) | 2021-03-19 | 2025-02-11 | Quest Diagnostics Investments Llc | Identification and quantitation of insulin-like growth factor-I variants by mass spectrometry |
| AU2023248408A1 (en) * | 2022-04-07 | 2024-10-31 | Quest Diagnostics Investments Llc | Detection of insulin-like growth factor-2 variants by mass spectrometry |
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| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
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| US5604099A (en) | 1986-03-13 | 1997-02-18 | Hoffmann-La Roche Inc. | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
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| DE3803275A1 (de) | 1988-02-04 | 1989-08-17 | Dornier Medizintechnik | Piezoelektrische stosswellenquelle |
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| IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
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| US5137806A (en) | 1989-12-11 | 1992-08-11 | Board Of Regents, The University Of Texas System | Methods and compositions for the detection of sequences in selected DNA molecules |
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| ES2453108T3 (es) | 2007-08-06 | 2014-04-04 | Orion Genomics, Llc | Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2 |
| CA2751758A1 (en) * | 2009-02-11 | 2010-08-19 | Orion Genomics Llc | Combinations of polymorphisms for determining allele-specific expression of igf2 |
-
2008
- 2008-08-06 ES ES08797299.8T patent/ES2453108T3/es active Active
- 2008-08-06 EP EP08797299.8A patent/EP2185726B1/en not_active Not-in-force
- 2008-08-06 CA CA2694832A patent/CA2694832A1/en not_active Abandoned
- 2008-08-06 ES ES13193708.8T patent/ES2543684T3/es active Active
- 2008-08-06 AU AU2008283902A patent/AU2008283902B2/en not_active Ceased
- 2008-08-06 EP EP15170550.6A patent/EP2952588A1/en not_active Withdrawn
- 2008-08-06 WO PCT/US2008/072356 patent/WO2009021054A2/en not_active Ceased
- 2008-08-06 US US12/672,066 patent/US8420315B2/en not_active Expired - Fee Related
- 2008-08-06 EP EP13193708.8A patent/EP2700723B1/en not_active Not-in-force
- 2008-08-06 JP JP2010520284A patent/JP5777340B2/ja not_active Expired - Fee Related
-
2013
- 2013-03-08 US US13/791,336 patent/US20130177911A1/en not_active Abandoned
- 2013-08-07 US US13/961,794 patent/US20140162255A1/en not_active Abandoned
- 2013-08-07 US US13/961,802 patent/US20130317125A1/en not_active Abandoned
- 2013-08-07 US US13/961,788 patent/US20130317124A1/en not_active Abandoned
-
2014
- 2014-02-18 US US14/182,503 patent/US20140162270A1/en not_active Abandoned
- 2014-02-18 US US14/182,495 patent/US20140163119A1/en not_active Abandoned
-
2015
- 2015-03-31 JP JP2015070799A patent/JP5902843B2/ja not_active Expired - Fee Related
-
2016
- 2016-03-10 JP JP2016046545A patent/JP2016116534A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5902843B2 (ja) | 2016-04-13 |
| US20110311967A1 (en) | 2011-12-22 |
| WO2009021054A3 (en) | 2009-04-16 |
| US20140162270A1 (en) | 2014-06-12 |
| WO2009021054A2 (en) | 2009-02-12 |
| EP2185726B1 (en) | 2014-01-08 |
| US20130177911A1 (en) | 2013-07-11 |
| ES2453108T3 (es) | 2014-04-04 |
| EP2700723B1 (en) | 2015-07-15 |
| US20130317124A1 (en) | 2013-11-28 |
| US8420315B2 (en) | 2013-04-16 |
| CA2694832A1 (en) | 2009-02-12 |
| US20140163119A1 (en) | 2014-06-12 |
| EP2700723A3 (en) | 2014-04-30 |
| AU2008283902A1 (en) | 2009-02-12 |
| ES2543684T3 (es) | 2015-08-21 |
| US20130317125A1 (en) | 2013-11-28 |
| EP2952588A1 (en) | 2015-12-09 |
| AU2008283902B2 (en) | 2014-03-13 |
| EP2700723A2 (en) | 2014-02-26 |
| US20140162255A1 (en) | 2014-06-12 |
| EP2185726A2 (en) | 2010-05-19 |
| JP2016116534A (ja) | 2016-06-30 |
| JP2010535507A (ja) | 2010-11-25 |
| JP2015156862A (ja) | 2015-09-03 |
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