JP5759890B2 - カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 - Google Patents

カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 Download PDF

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JP5759890B2
JP5759890B2 JP2011502032A JP2011502032A JP5759890B2 JP 5759890 B2 JP5759890 B2 JP 5759890B2 JP 2011502032 A JP2011502032 A JP 2011502032A JP 2011502032 A JP2011502032 A JP 2011502032A JP 5759890 B2 JP5759890 B2 JP 5759890B2
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cldc
vaccine
administration
cationic lipid
adjuvant
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JP2011515490A (ja
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ジェフリー・フェアマン
マーラ・ボーン
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Juvaris Biotherapeutics Inc
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JP2011502032A 2008-03-25 2009-03-25 カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 Expired - Fee Related JP5759890B2 (ja)

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US3938108P 2008-03-25 2008-03-25
US61/039,381 2008-03-25
PCT/US2009/038307 WO2009120811A1 (en) 2008-03-25 2009-03-25 Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)

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JP2011515490A JP2011515490A (ja) 2011-05-19
JP2011515490A5 JP2011515490A5 (https=) 2012-05-17
JP5759890B2 true JP5759890B2 (ja) 2015-08-05

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US (1) US8945590B2 (https=)
EP (1) EP2257306B1 (https=)
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BR (1) BRPI0910036B8 (https=)
CA (1) CA2719614C (https=)
WO (1) WO2009120811A1 (https=)

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EP2257306B1 (en) 2008-03-25 2014-05-07 Juvaris Biotherapeutics, Inc. Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)
BRPI1010803A2 (pt) * 2009-05-14 2018-06-12 Bayer Animal Health Gmbh "resposta imune aumentada na espécie aviária"
WO2011106607A2 (en) * 2010-02-26 2011-09-01 Juvaris Biotherapeutics, Inc. Subunit vaccines for herpes viruses and methods of use
UY33821A (es) 2010-12-22 2012-07-31 Bayer Animal Health Gmbh Respuesta inmune potenciada en la especie bovina
CN105579582A (zh) 2013-07-25 2016-05-11 埃克西奎雷股份有限公司 用于预防和治疗用途的作为免疫刺激剂的基于球形核酸的构建体
EP3110940A1 (en) 2014-02-28 2017-01-04 Bayer Animal Health GmbH Immunostimulatory plasmids
AU2015269412B2 (en) 2014-06-04 2020-03-12 Exicure Operating Company Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
KR20170078843A (ko) 2014-11-21 2017-07-07 노오쓰웨스턴 유니버시티 구형 핵산 나노입자 접합체의 서열 특이적 세포 흡수
EP3328423B1 (en) * 2015-07-31 2021-05-26 Bayer Animal Health GmbH Enhanced immune response in fish
AU2016302436B2 (en) 2015-07-31 2022-03-03 Elanco Animal Health Gmbh Enhanced immune response in porcine species
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
EP3533463A4 (en) * 2016-10-31 2020-06-17 Eyegene Inc. IMMUNE REACTION REGULATING SUBSTANCE AND VACCINE COMPOSITION THEREFOR
US11696954B2 (en) 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties

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US5534496A (en) 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
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EP1006999A2 (en) * 1997-07-08 2000-06-14 Chiron Corporation Use of submicron oil-in-water emulsions with dna vaccines
DK1009413T3 (da) 1997-09-05 2007-06-11 Univ California Anvendelse af immunstimulerende oligonukleotider til forebyggelse eller behandling af astma
US6693086B1 (en) 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
US20040247662A1 (en) 1998-06-25 2004-12-09 Dow Steven W. Systemic immune activation method using nucleic acid-lipid complexes
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
US20050013812A1 (en) * 2003-07-14 2005-01-20 Dow Steven W. Vaccines using pattern recognition receptor-ligand:lipid complexes
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US20090208781A1 (en) * 2008-02-19 2009-08-20 Skinner George A Method for operating a fuel cell system
EP2249843A4 (en) 2008-02-24 2013-05-08 Us Gov Health & Human Serv USE OF IMMUNOGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF INFECTIONS BY DISEASES
EP2257306B1 (en) 2008-03-25 2014-05-07 Juvaris Biotherapeutics, Inc. Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)
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BRPI1010803A2 (pt) 2009-05-14 2018-06-12 Bayer Animal Health Gmbh "resposta imune aumentada na espécie aviária"

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BRPI0910036B8 (pt) 2021-05-25
US8945590B2 (en) 2015-02-03
US20090263423A1 (en) 2009-10-22
CA2719614A1 (en) 2009-10-01
EP2257306A1 (en) 2010-12-08
WO2009120811A1 (en) 2009-10-01
CA2719614C (en) 2018-05-01
BRPI0910036B1 (pt) 2020-07-21
EP2257306B1 (en) 2014-05-07
JP2011515490A (ja) 2011-05-19
BRPI0910036A2 (pt) 2015-08-11

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