JP5704789B2 - 耐アルコール性剤形 - Google Patents

耐アルコール性剤形 Download PDF

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Publication number
JP5704789B2
JP5704789B2 JP2007552587A JP2007552587A JP5704789B2 JP 5704789 B2 JP5704789 B2 JP 5704789B2 JP 2007552587 A JP2007552587 A JP 2007552587A JP 2007552587 A JP2007552587 A JP 2007552587A JP 5704789 B2 JP5704789 B2 JP 5704789B2
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JP
Japan
Prior art keywords
opioid
controlled release
use according
matrix formulation
minutes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP2007552587A
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English (en)
Japanese (ja)
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JP2008528534A5 (https=
JP2008528534A (ja
Inventor
マニオン，リチャード，オー．
マッケナ，ウィリアム，エイチ．
オドネル，エドワード，ピー．
ダナゲル，ヘレン，カスリーン
ヘイズ，ジェフリー，ジェラルド
モハマド，ハッサン
プラター，デレック，アラン
タンバー，ハルジット
ワルデン，マルコム
ホワイトナット，スティーブ
フライシャー，ウルフガング
アーン，ウド
シュピッツレー，クリスチャン
レウナー，クリスチャン
Original Assignee
ユーロ−セルティーク エス．エイ．
ユーロ−セルティーク エス．エイ．
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36297284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5704789(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB0501638.1A external-priority patent/GB0501638D0/en
Priority claimed from PCT/GB2005/050014 external-priority patent/WO2005079760A1/en
Application filed by ユーロ−セルティーク エス．エイ．, ユーロ−セルティーク エス．エイ． filed Critical ユーロ−セルティーク エス．エイ．
Publication of JP2008528534A publication Critical patent/JP2008528534A/ja
Publication of JP2008528534A5 publication Critical patent/JP2008528534A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2007552587A 2005-01-28 2006-01-27 耐アルコール性剤形 Expired - Lifetime JP5704789B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0501638.1 2005-01-28
GBGB0501638.1A GB0501638D0 (en) 2005-01-28 2005-01-28 Particulates
GBPCT/GB2005/050014 2005-02-11
PCT/GB2005/050014 WO2005079760A1 (en) 2004-02-12 2005-02-11 Particulates
US67050605P 2005-04-12 2005-04-12
US60/670,506 2005-04-12
US73033905P 2005-10-26 2005-10-26
US60/730,339 2005-10-26
PCT/EP2006/000727 WO2006079550A2 (en) 2005-01-28 2006-01-27 Alcohol resistant dosage forms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012284017A Division JP2013100306A (ja) 2005-01-28 2012-12-27 耐アルコール性剤形

Publications (3)

Publication Number Publication Date
JP2008528534A JP2008528534A (ja) 2008-07-31
JP2008528534A5 JP2008528534A5 (https=) 2008-10-23
JP5704789B2 true JP5704789B2 (ja) 2015-04-22

Family

ID=36297284

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007552587A Expired - Lifetime JP5704789B2 (ja) 2005-01-28 2006-01-27 耐アルコール性剤形

Country Status (14)

Country Link
US (1) US20070259045A1 (https=)
EP (4) EP2289491A1 (https=)
JP (1) JP5704789B2 (https=)
KR (2) KR20090029856A (https=)
CN (1) CN101132772B (https=)
AP (1) AP2274A (https=)
AU (1) AU2006208627B8 (https=)
BR (1) BRPI0606339A2 (https=)
CA (1) CA2594373A1 (https=)
EA (1) EA015615B1 (https=)
GE (1) GEP20105052B (https=)
IL (1) IL184858A (https=)
MX (1) MX2007009162A (https=)
WO (1) WO2006079550A2 (https=)

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EP2319499A1 (en) 2011-05-11
WO2006079550A3 (en) 2006-12-14
US20070259045A1 (en) 2007-11-08
CN101132772A (zh) 2008-02-27
CA2594373A1 (en) 2006-08-03
IL184858A (en) 2016-03-31
WO2006079550A2 (en) 2006-08-03
MX2007009162A (es) 2007-10-23
EA200701595A1 (ru) 2008-02-28
KR20070104443A (ko) 2007-10-25
EP3228308A1 (en) 2017-10-11
EP2289491A1 (en) 2011-03-02
AP2274A (en) 2011-08-19
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AU2006208627A1 (en) 2006-08-03
KR20090029856A (ko) 2009-03-23
AP2007004099A0 (en) 2007-08-31
EA015615B1 (ru) 2011-10-31
AU2006208627B8 (en) 2009-08-13
EP1771160A2 (en) 2007-04-11
KR100905511B1 (ko) 2009-07-01
JP2008528534A (ja) 2008-07-31

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