JP5701752B2 - 抗p2x7ペプチドおよびエピトープ - Google Patents

抗p2x7ペプチドおよびエピトープ Download PDF

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Publication number
JP5701752B2
JP5701752B2 JP2011515029A JP2011515029A JP5701752B2 JP 5701752 B2 JP5701752 B2 JP 5701752B2 JP 2011515029 A JP2011515029 A JP 2011515029A JP 2011515029 A JP2011515029 A JP 2011515029A JP 5701752 B2 JP5701752 B2 JP 5701752B2
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antibody
region
receptor
antibodies
functional
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Japanese (ja)
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JP2011526249A5 (OSRAM
JP2011526249A (ja
Inventor
ジュリアン・アレクサンダー・バーデン
アンガス・ギドリー−ベアード
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バイオセプター・インターナショナル・リミテッド
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Priority claimed from AU2008903451A external-priority patent/AU2008903451A0/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011515029A 2008-07-04 2009-07-03 抗p2x7ペプチドおよびエピトープ Active JP5701752B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2008903451 2008-07-04
AU2008903451A AU2008903451A0 (en) 2008-07-04 Composite peptide
PCT/AU2009/000869 WO2010000041A1 (en) 2008-07-04 2009-07-03 Anti- p2x7 peptides and epitopes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014222949A Division JP2015038144A (ja) 2008-07-04 2014-10-31 抗p2x7ペプチドおよびエピトープ

Publications (3)

Publication Number Publication Date
JP2011526249A JP2011526249A (ja) 2011-10-06
JP2011526249A5 JP2011526249A5 (OSRAM) 2013-10-24
JP5701752B2 true JP5701752B2 (ja) 2015-04-15

Family

ID=41465424

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011515029A Active JP5701752B2 (ja) 2008-07-04 2009-07-03 抗p2x7ペプチドおよびエピトープ
JP2014222949A Pending JP2015038144A (ja) 2008-07-04 2014-10-31 抗p2x7ペプチドおよびエピトープ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014222949A Pending JP2015038144A (ja) 2008-07-04 2014-10-31 抗p2x7ペプチドおよびエピトープ

Country Status (12)

Country Link
US (3) US8597643B2 (OSRAM)
EP (1) EP2318438B1 (OSRAM)
JP (2) JP5701752B2 (OSRAM)
KR (1) KR101701300B1 (OSRAM)
CN (1) CN102143978B (OSRAM)
AU (1) AU2009266430B2 (OSRAM)
BR (1) BRPI0915367B8 (OSRAM)
CA (1) CA2729868C (OSRAM)
ES (1) ES2610225T3 (OSRAM)
IL (2) IL210220A (OSRAM)
NZ (1) NZ590146A (OSRAM)
WO (1) WO2010000041A1 (OSRAM)

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EP1961767B1 (en) 2001-01-17 2012-03-07 Biosceptre International Limited Diagnosis and treatment of cancers and other conditions
US8293491B2 (en) 2007-09-14 2012-10-23 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
JP5670192B2 (ja) 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規p2x7エピトープ
AU2009266430B2 (en) 2008-07-04 2014-08-14 Biosceptre International Limited Anti- P2X7 peptides and epitopes
JP5936067B2 (ja) 2009-08-20 2016-06-15 バイオセプター・(オーストラリア)・ピーティーワイ・リミテッド 抗p2x7受容体抗体およびその断片
EP2516470B1 (en) 2009-12-24 2018-02-07 Biosceptre (Aust) Pty Ltd Antibodies to non-functional oligomeric p2x7 receptors
AU2011301153B2 (en) 2010-09-10 2014-11-27 Biosceptre International Limited Companion animal treatments
ES2689272T3 (es) 2011-07-01 2018-11-13 Biosceptre (Aust) Pty Ltd Terapia de combinación
US20180037650A1 (en) * 2015-04-02 2018-02-08 Biosceptre (Uk) Limited Pain Treatment
US12121539B2 (en) * 2015-09-11 2024-10-22 Biosceptre (Aust) Pty Ltd Chimeric antigen receptors and uses thereof
CA3035835A1 (en) 2016-10-21 2018-04-26 Biosceptre (Uk) Limited Cytotoxic particles
US20250282844A1 (en) * 2021-04-08 2025-09-11 Biosceptre (Aust) Pty Ltd Methods for controlling immune cell activity
JP2025531030A (ja) * 2022-09-14 2025-09-19 バイオセプター (オースト) プロプライエタリー・リミテッド 免疫細胞のインビボ検出
CN120166997A (zh) * 2022-09-14 2025-06-17 生物权威(澳大利亚)有限责任公司 检测免疫细胞的方法
EP4587465A1 (en) * 2022-09-14 2025-07-23 Biosceptre (Aust) Pty Ltd Enrichment of engineered immune cells

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EP0760850A1 (en) 1994-05-27 1997-03-12 Glaxo Group Limited P2x RECEPTORS (PURINOCEPTOR FAMILY)
JPH11510393A (ja) 1995-08-09 1999-09-14 インスティチュート ナショナル ドゥ ラ セント エト ドゥ ラ リサーチェ メディカル 白血病マーカーとしておよび乳癌の予後において有用な単離された核酸分子
WO1997041222A1 (en) 1996-04-30 1997-11-06 Smithkline Beecham P.L.C. HUMAN P2x4 RECEPTOR SPLICE-VARIANTS
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US6306393B1 (en) * 1997-03-24 2001-10-23 Immunomedics, Inc. Immunotherapy of B-cell malignancies using anti-CD22 antibodies
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DE19829473C2 (de) * 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
EP1157038A4 (en) 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
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EP1961767B1 (en) * 2001-01-17 2012-03-07 Biosceptre International Limited Diagnosis and treatment of cancers and other conditions
TWI329648B (en) * 2001-09-03 2010-09-01 Intreat Pty Ltd Diagnosis and treatment of cancers and other conditions
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WO2006136004A1 (en) * 2005-05-05 2006-12-28 Medicure International Inc. Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds
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WO2008043146A1 (en) * 2006-10-10 2008-04-17 Biosceptre International Limited Antibodies against non functional p2x7 receptor
US8067550B2 (en) * 2006-10-10 2011-11-29 Biosceptre International Limited Hybridomas producing antibodies against non functional P2X7 receptor
US8293491B2 (en) * 2007-09-14 2012-10-23 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
JP5670192B2 (ja) * 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規p2x7エピトープ
AU2009266430B2 (en) 2008-07-04 2014-08-14 Biosceptre International Limited Anti- P2X7 peptides and epitopes
JP5936067B2 (ja) * 2009-08-20 2016-06-15 バイオセプター・(オーストラリア)・ピーティーワイ・リミテッド 抗p2x7受容体抗体およびその断片
EP2516470B1 (en) 2009-12-24 2018-02-07 Biosceptre (Aust) Pty Ltd Antibodies to non-functional oligomeric p2x7 receptors
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Also Published As

Publication number Publication date
IL210220A (en) 2016-04-21
KR20110031222A (ko) 2011-03-24
BRPI0915367A2 (pt) 2015-11-03
ES2610225T3 (es) 2017-04-26
US9328155B2 (en) 2016-05-03
IL232394A0 (en) 2014-06-30
US20160199442A1 (en) 2016-07-14
BRPI0915367B1 (pt) 2020-10-13
EP2318438B1 (en) 2016-11-02
KR101701300B1 (ko) 2017-02-01
NZ590146A (en) 2012-09-28
US8597643B2 (en) 2013-12-03
IL232394A (en) 2016-04-21
AU2009266430A1 (en) 2010-01-07
EP2318438A1 (en) 2011-05-11
US20140135475A1 (en) 2014-05-15
IL210220A0 (en) 2011-03-31
AU2009266430A8 (en) 2011-03-10
CN102143978A (zh) 2011-08-03
US10238716B2 (en) 2019-03-26
CA2729868C (en) 2018-07-10
BRPI0915367B8 (pt) 2021-05-25
AU2009266430B2 (en) 2014-08-14
WO2010000041A1 (en) 2010-01-07
JP2015038144A (ja) 2015-02-26
CA2729868A1 (en) 2010-01-07
US20110110959A1 (en) 2011-05-12
EP2318438A4 (en) 2012-11-21
CN102143978B (zh) 2015-02-18
JP2011526249A (ja) 2011-10-06

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