JP5679992B2 - 複合体および生産方法 - Google Patents

複合体および生産方法 Download PDF

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Publication number
JP5679992B2
JP5679992B2 JP2011544926A JP2011544926A JP5679992B2 JP 5679992 B2 JP5679992 B2 JP 5679992B2 JP 2011544926 A JP2011544926 A JP 2011544926A JP 2011544926 A JP2011544926 A JP 2011544926A JP 5679992 B2 JP5679992 B2 JP 5679992B2
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JP
Japan
Prior art keywords
lactalbumin
recombinant protein
biologically active
complex
sequence
Prior art date
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JP2011544926A
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English (en)
Japanese (ja)
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JP2012514466A5 (enExample
JP2012514466A (ja
Inventor
ペーテルソン−カストバーグ、ジェニー
スヴァンボルグ、カタリナ
ハン モック、ケネス
ハン モック、ケネス
モスベルグ、アン−クリスティン
Original Assignee
ハムレット・ファルマ・アーベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0900260A external-priority patent/GB0900260D0/en
Priority claimed from GB0906199A external-priority patent/GB0906199D0/en
Application filed by ハムレット・ファルマ・アーベー filed Critical ハムレット・ファルマ・アーベー
Publication of JP2012514466A publication Critical patent/JP2012514466A/ja
Publication of JP2012514466A5 publication Critical patent/JP2012514466A5/ja
Application granted granted Critical
Publication of JP5679992B2 publication Critical patent/JP5679992B2/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2011544926A 2009-01-09 2010-01-08 複合体および生産方法 Active JP5679992B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0900260.1 2009-01-09
GB0900260A GB0900260D0 (en) 2009-01-09 2009-01-09 Complex and production process
GB0906199A GB0906199D0 (en) 2009-04-09 2009-04-09 Complex and production process
GB0906199.5 2009-04-09
PCT/GB2010/050024 WO2010079362A1 (en) 2009-01-09 2010-01-08 Complex and production process

Publications (3)

Publication Number Publication Date
JP2012514466A JP2012514466A (ja) 2012-06-28
JP2012514466A5 JP2012514466A5 (enExample) 2013-02-28
JP5679992B2 true JP5679992B2 (ja) 2015-03-04

Family

ID=42026257

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011544926A Active JP5679992B2 (ja) 2009-01-09 2010-01-08 複合体および生産方法

Country Status (8)

Country Link
US (1) US8796218B2 (enExample)
EP (1) EP2385954B1 (enExample)
JP (1) JP5679992B2 (enExample)
CN (1) CN102348721A (enExample)
AU (1) AU2010204178B2 (enExample)
CA (1) CA2752490C (enExample)
DK (1) DK2385954T3 (enExample)
WO (1) WO2010079362A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2385954T3 (da) 2009-01-09 2013-06-17 Hamlet Pharma Ab Kompleks og fremstillingsproces
DK2643010T3 (en) 2010-11-24 2017-02-27 Hamlet Pharma Ab BIOLOGICAL ACTIVE COMPLEX AND ITS PREPARATION
WO2014023976A1 (en) 2012-08-09 2014-02-13 Hamlet Pharma Ab Prophylactic and nutraceutical therapy
CN106636157A (zh) * 2016-09-01 2017-05-10 锦州医科大学 一种突变α‑乳清蛋白表达载体、制备方法及其应用
GB201621752D0 (en) * 2016-12-20 2017-02-01 Hamlet Pharma Ab Therapeutically active complexes
GB201707715D0 (en) * 2017-05-14 2017-06-28 Hamlet Pharma Ab Preperation of biologically active complexes
WO2021032807A1 (en) 2019-08-20 2021-02-25 Hamlet Pharma Ab Combination of a chemotherapeutic agent and alpha-lactoglubulin-oleic acid complex for cancer therapy
GB202015836D0 (en) * 2020-10-06 2020-11-18 Hamlet Pharma Ab Compositions
GB202303177D0 (en) 2023-03-03 2023-04-19 Linnane Pharma Ab Method of predicting response to treatment
WO2025186107A1 (en) 2024-03-04 2025-09-12 Linnane Pharma Ab Therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2286860T3 (es) 1997-11-21 2007-12-01 Nya Hamlet Pharma Ab Proceso de produccion de lactoalbumina.
GB9725126D0 (en) 1997-11-27 1998-01-28 Svanborg Catharina Therapeutic agents
AU5928599A (en) 1999-09-09 2001-04-10 Efa Sciences Llc. Methods for treating cell proliferative disorders including cancer
US6639089B2 (en) 2000-11-08 2003-10-28 Soda Aromatic Co., Ltd. Anticancer agents, perfumes or foods and drinks
GB0205347D0 (en) 2002-03-07 2002-04-24 Svanborg Catharina Biologically active complex
GB0508880D0 (en) * 2005-05-03 2005-06-08 Hamlet Pharma Ab Novel therapies and methods of screening for therapeutic compounds
US20080115228A1 (en) * 2006-11-15 2008-05-15 Yahoo! Inc. Rights engine
WO2008058547A2 (en) 2006-11-17 2008-05-22 Nya Hamlet Pharma Ab Alpha-lactalbumin composition
WO2008138348A1 (en) * 2007-05-09 2008-11-20 Nya Hamlet Pharma Ab Preparation of complexed lactalbumin
DK2385954T3 (da) 2009-01-09 2013-06-17 Hamlet Pharma Ab Kompleks og fremstillingsproces
WO2010131237A1 (en) 2009-05-13 2010-11-18 Agriculture And Food Development Authority (Teagasc) A process for producing a biologically active globular protein complex
DK2643010T3 (en) 2010-11-24 2017-02-27 Hamlet Pharma Ab BIOLOGICAL ACTIVE COMPLEX AND ITS PREPARATION

Also Published As

Publication number Publication date
CN102348721A (zh) 2012-02-08
CA2752490C (en) 2020-03-10
US20120028883A1 (en) 2012-02-02
DK2385954T3 (da) 2013-06-17
EP2385954B1 (en) 2013-04-03
CA2752490A1 (en) 2010-07-15
WO2010079362A1 (en) 2010-07-15
AU2010204178B2 (en) 2015-10-29
US8796218B2 (en) 2014-08-05
JP2012514466A (ja) 2012-06-28
AU2010204178A1 (en) 2011-09-01
EP2385954A1 (en) 2011-11-16

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