JP5670781B2 - Infusion container - Google Patents

Description

  The present invention relates to an infusion container in which a drug can be prepared and blended in a drug solution such as an infusion solution.

Prior to infusion to the patient, a drug that is difficult to pre-mix in the infusion, such as vitamins or antibiotics, is mixed and dissolved in a vial or soft bag containing the infusion. Has been prepared. In order to prepare such a chemical solution aseptically and with a simple operation, a drug container containing a drug mixed with the chemical solution is attached to a soft bag containing the chemical solution, and the drug container is infused during infusion. There has been proposed an infusion container in which a breakable portion (fragile portion) provided is folded and broken through a soft bag so that the drug container communicates with the soft bag to mix the drug and the drug solution.
As such an infusion container, Japanese Patent Application Laid-Open No. 2003-010285 (Patent Document 1) discloses a breaking operation in which the strength of the breaking operation portion is large (rigid), and has excellent gripping and operability during the breaking operation. An infusion container having a portion is disclosed.

Japanese Patent Application Laid-Open No. 2003-159309 (Patent Document 2) proposes an infusion container including a drug container that can reliably break a fragile portion by a single bending operation.
Further, the applicant of the present application has proposed the one disclosed in Japanese Patent Application Laid-Open No. 2007-222243 (Patent Document 3).
The infusion container 1 includes a soft bag 2 in which a drug solution is stored, and a hard drug container 3 in which a drug 11 attached to the soft bag 2 and mixed with the drug solution is stored. The medicine container 3 includes a hollow medicine container 30 in which the medicine 11 is housed and a breakable portion 33 that is formed on the distal end side of the medicine container 30 so that the medicine 11 inside the medicine container 30 can be discharged by breaking. The drug container main body 5 having an operation part 34 provided on the distal end side of the breakable part 33 for performing the breaking operation of the breakable part 33, and the breakable part 33 without contacting the breakable part 33. And a cylindrical portion 6 fixed to the drug container main body 5 and / or the soft bag 2 on the proximal end side from the distal end portion 63. The distal end of the tubular portion 6 is positioned on the side of the predetermined length operation portion 34 with respect to the breakable portion, and the tubular portion 6 of the breakable portion 33 of the breakable portion 33 when the breakable portion 33 is broken by the operation portion 34. It is intended to prevent exposure from.

JP2003-010285A JP 2003-159309 A JP 2007-222243 A

The above-mentioned infusion container has a sufficient effect. However, when the present inventors examined, during the rupture operation of the breakable portion of the drug container, for example, although rare, the breakable portion of the breakable portion (break end) or the base end portion of the broken operation portion, It was found that strong pressure against a soft bag could damage the bag and cause liquid leakage.
Therefore, the present invention is an infusion container including a drug container having a breakable portion, and is caused by contact between the breakable end of the breakable portion and the base end portion of the operation portion during the breaking operation of the breakable portion. An infusion container in which damage to a soft bag is reliably prevented is provided.

What achieves the above object is as follows.
(1) An infusion container comprising a soft bag in which a drug solution is stored and a hard drug container that is attached to the soft bag and stores a drug for mixing with the drug solution, A hollow medicine container that contains a medicine, a breakable part that is formed on the distal end side of the medicine container and can discharge the medicine inside the medicine container by breaking, and is provided on the distal side from the breakable part. A drug container body portion having an operation portion for performing a breaking operation of the breakable portion, and encircling the breakable portion coaxially at a distal end portion, and fixed to the drug container body portion or the soft bag. A cylindrical diameter portion, and the cylindrical portion is reduced in diameter toward the distal end, and the reduced diameter distal end portion enveloping the breakable portion and the proximal end portion of the operation portion; and the reduced diameter distal end portion Extend further to the tip side, A base end portion of the operation portion that is exposed to be encapsulated, and the contact of the breakable end portion of the breakable portion and the base end portion of the operation portion with the inner surface of the flexible bag during the breaking operation of the operation portion is regulated. An infusion container comprising a cylindrical flexible encapsulating part.

(2) The cylindrical flexible encapsulating portion encapsulates the reduced diameter tip portion, further extends beyond the tip of the reduced diameter tip portion, and is exposed from the reduced diameter tip portion. The infusion container according to (1), wherein the proximal end portion of the operation unit is encapsulated.
(3) The infusion container according to the above (1) or (2), wherein the cylindrical flexible encapsulating portion extends substantially at the same inner diameter or extends so as to expand in a tapered shape. .
(4) The breakable portion starts to break at a point where the breakable portion is provided as a fulcrum by a rupture operation of the operation portion, starts to break from a portion facing the fulcrum, and breaks the breakable portion As a result of the progress, the contact between the operation portion and the reduced diameter tip portion of the cylindrical portion becomes a second fulcrum, and the breaking operation proceeds, so that the operation portion is more than the drug container main body portion in the breakable portion. The infusion container according to any one of (1) to (3), which is to be separated.
(5) The said cylindrical part is being fixed to the said chemical | medical agent container main-body part and the said soft bag, and the said chemical | medical agent container main-body part is attached to the said soft bag via the said cylindrical part (1). Thru | or the container for infusion in any one of (4).
(6) In the inner surface of the reduced diameter tip portion of the cylindrical portion, a groove extending from the tip of the reduced diameter tip portion to a position beyond the breakable portion of the drug container main body portion is formed. The container for infusion according to any one of (1) to (5).

Moreover, what achieves the said objective is as follows.
(7) An infusion container comprising a soft bag containing a drug solution, and a hard drug container attached to the soft bag and containing a drug for mixing with the drug solution, wherein the drug container includes: A hollow medicine storage part in which a medicine is stored, a breakable part formed at the distal end side of the medicine storage part and capable of discharging the medicine inside the medicine storage part by breaking, and on the distal side from the breakable part And a medicine container main body part having an operation part for performing a breaking operation of the breakable part, and a distal end part of the medicine storage part is a reduced diameter part that is reduced in diameter toward the breakable part. The medicine container body extends from the medicine container to the distal end side, encloses and separates the breakable portion and the proximal end portion of the operation portion, and is capable of being broken during the breaking operation of the operation portion. Broken end of the part and the base of the operation part An infusion container comprising a cylindrical flexible encapsulating portion that regulates contact of an end portion with the inner surface of the soft bag.

(8) The infusion container according to (7), wherein the cylindrical flexible encapsulating portion extends substantially at the same inner diameter or extends so as to expand in a tapered shape.
(9) The infusion container according to any one of (1) to (8), wherein the cylindrical flexible encapsulating portion is thinner toward the tip.
(10) Any of the above (1) to (9), wherein the drug container is a discharge port that seals the opening of the drug container main body and has a sealing part that can be connected to a medical needle tube A container for infusion according to crab.
(11) The inside of the medicine container main body contains a needle tube entry inhibiting member that inhibits the medical needle tube from entering the medicine container body when the breakable portion is not broken (10 ) Infusion container.
(12) The infusion container according to any one of (1) to (9), wherein the infusion container includes a discharge port for discharging the drug solution or the mixed solution of the drug solution and the drug in the soft bag. Infusion container.

An infusion container of the present invention is an infusion container comprising a soft bag containing a chemical solution and a hard drug container attached to the soft bag and containing a drug for mixing with the chemical solution, , A hollow medicine container that contains medicine, and a breakable part that is formed on the distal end side of the medicine container and that can discharge the medicine inside the medicine container by breakage, and is breakable provided on the distal side from the breakable part A drug container main body portion having an operation portion for performing a breaking operation of the portion, and a cylindrical portion fixed to the drug container main body portion or the soft bag while coaxially encapsulating the breakable portion at the distal end portion. The cylindrical portion has a reduced diameter toward the distal end, envelops the breakable portion and the proximal end of the operation portion, and extends from the reduced diameter distal end to the distal side, and the reduced diameter distal portion Enclose the base part of the operation part that is exposed more, and operate it Of comprising a tubular flexible encapsulation portion for restricting contact to the inner surface of the flexible bag of the base end portion of the broken end and the operation portion of the breakable portion in the fracture operation.
The infusion container of the present invention is an infusion container comprising a soft bag containing a chemical solution and a hard drug container attached to the soft bag and containing a drug for mixing with the chemical solution. The container has a hollow medicine storage part in which the medicine is stored, a breakable part formed on the distal end side of the medicine storage part and capable of discharging the medicine inside the medicine storage part by breaking, and on the distal side from the breakable part A drug container main body portion having an operation portion for performing a breaking operation of the breakable portion provided, and the distal end portion of the drug storage portion is a reduced diameter portion that is reduced in diameter toward the breakable portion, The container body extends in the distal direction from the medicine container, encloses and separates the breakable portion and the proximal end portion of the operation portion, and breaks the breakable portion and the base of the operation portion during the breaking operation of the operation portion. Restricts contact of the end with the inner surface of the soft bag That includes a tubular flexible encapsulation unit.
In the infusion container of the present invention, even when the breaking portion (breaking end) of the breakable portion or the proximal end portion of the broken operating portion is strongly pressed against the inner surface direction of the soft bag during the breaking operation, Since the rupture part (breaking end) and the base end part of the ruptured operation part do not contact the inner surface of the soft bag but contact the cylindrical flexible enveloping part, the rupture part (breaking end) and the ruptured operation part The base end of the bag prevents the soft bag from being damaged.

FIG. 1 is a front view of an infusion container according to an embodiment of the present invention. FIG. 2 is an enlarged front view of a drug container with a discharge port function used in the infusion container of FIG. FIG. 3 is a side view of the medicine container of FIG. 4 is a cross-sectional view of the drug container of FIG. 2 along the line AA. FIG. 5 is an enlarged cross-sectional view of the drug container of FIG. 3 along the line BB. FIG. 6 is an enlarged cross-sectional view of the drug container of FIG. FIG. 7 is a front view of a drug container main body used in the drug container of FIG. FIG. 8 is a cross-sectional view of a cylindrical portion used in the medicine container of FIG. FIG. 9 is a front view of a needle tube entry inhibiting member used in the medicine container of FIG. FIG. 10 is an enlarged plan view of the needle tube penetration inhibiting member of FIG. FIG. 11 is a partially enlarged view of FIG. FIG. 12 is a cross-sectional view (during breakage) for explaining a method of using the infusion container according to the embodiment of the present invention. FIG. 13: is sectional drawing of the other Example of the chemical | medical agent container with a discharge port function used for the infusion container of this invention. FIG. 14 is a cross-sectional view of another embodiment of the drug container with a discharge port function used in the infusion container of the present invention. FIG. 15 is a front view of an infusion container according to another embodiment of the present invention. 16 is an enlarged front view of a drug container used in the infusion container of FIG. 17 is a cross-sectional view of the drug container of FIG. FIG. 18 is a front view of an infusion container according to another embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
The infusion container 1 of the present invention includes a soft bag 2 in which a chemical solution is stored, and a hard drug container 3 in which a drug 8 attached to the soft bag 2 and mixed with the chemical solution is stored. The medicine container 3 has a hollow medicine container 54 in which the medicine 8 is housed and a breakable part 56 that is formed on the distal end side of the medicine container 54 and that can discharge the medicine 8 inside the medicine container 54 by breakage. The medicine container body 5 having an operation portion 55 provided on the distal end side of the breakable portion 56 for performing the breaking operation of the breakable portion 56, and the breakable portion 56 without contacting the breakable portion 56. And a cylindrical part 6 fixed to the drug container main body part 5 or the soft bag 2. The cylindrical portion 6 is reduced in diameter toward the distal end, and a reduced diameter distal end portion 64 that encloses the breakable portion 56 and the proximal end portion 55a of the operation portion 55, and extends from the reduced diameter distal end portion 64 toward the distal end side. The proximal end portion of the operation portion 55 exposed from the distal end portion 64 is encapsulated, and the inner surface of the flexible bag 2 of the breakable end portion 55b of the breakable portion 56 and the proximal end portion 55a of the operation portion 55 during the breaking operation of the operation portion 55 A cylindrical flexible encapsulating portion 63 that restricts contact with the tube is provided.

The infusion container of the present invention will be described using an embodiment including a drug container with a discharge port function.
The infusion container 1 of this embodiment is formed of a flexible material, and has a soft bag 2 having a drug chamber 11 serving as a drug container inside, and a discharge port function attached to the drug chamber 11 of the soft bag 2. This is a drug-containing infusion container including the drug container 3 and a drug solution filled in the drug chamber 11.
Further, as shown in FIG. 1, seal portions 21 and 22 are provided on one end side and the other end side of the soft bag 2. The upper end seal portion 21 is provided with a suspension opening 25. In addition, a fixing portion 24 for fixing the medicine container 3 with the discharge port function is provided in the central portion of the lower end side sealing portion 22.
The soft bag 2 of the infusion container 1 is formed of a soft synthetic resin. The flexible bag 2 is preferably formed into a cylindrical shape by an inflation molding method. The soft bag 2 may be manufactured by various methods such as a blow molding method and a coextrusion inflation method.
The soft bag 2 preferably has a water vapor barrier property. As the degree of water vapor barrier property, the water vapor permeability is preferably 50 g / m ² · 24 hrs · 40 ° C. · 90% RH or less, more preferably 10 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. More preferably, it is 1 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. This water vapor permeability is measured by the method described in JISK7129 (Method A). Thus, since the soft bag 2 has a water vapor barrier property, the evaporation of moisture from the inside of the infusion container 1 can be prevented. As a result, it is possible to prevent reduction and concentration of the medicine (specifically, chemical solution) to be filled. Moreover, the invasion of water vapor from the outside of the infusion container 1 can be prevented.

Examples of the material for forming such a flexible bag 2 include various types such as polyethylene (PE), polypropylene (PP), polybutadiene, polyolefin such as ethylene-vinyl acetate copolymer (EVA), olefin elastomer, and styrene elastomer. Thermoplastic elastomers or those arbitrarily combined (blend resin, polymer alloy, laminate, etc.) can be mentioned. And it is preferable that the resin material to be used has the heat resistance and water resistance which can endure high pressure steam sterilization (autoclave sterilization).
In the present invention, it is preferable that the material for forming the soft bag 2 includes polyolefin. As a material for forming the flexible bag 2, polyethylene or polypropylene, a styrene thermoplastic elastomer such as a styrene-butadiene copolymer or a styrene-ethylene-butylene-styrene block copolymer, or an ethylene-propylene copolymer is particularly preferable. And a soft resin obtained by blending and softening an olefinic thermoplastic elastomer such as an ethylene-butene copolymer or a propylene-α-olefin copolymer. This material is preferable in that it has high strength and flexibility, heat resistance (particularly heat resistance during sterilization) and water resistance, and is particularly excellent in workability and can reduce manufacturing costs.

The soft bag may have a single-layer structure (single-layer body) made of the materials described above, or a multilayer in which a plurality of layers (particularly layers of different materials) are stacked for various purposes. A laminated body may be sufficient. In the case of a multilayer laminate, a plurality of resin layers may be stacked, or a metal layer may be stacked on at least one resin layer. In the case where a plurality of resin layers are stacked, the advantages of the respective resins can be provided together. For example, the impact resistance of the soft bag 2 can be improved, or blocking resistance can be imparted. Moreover, in the case of a thing with a metal layer, the gas barrier property etc. of the soft bag 2 can be improved. For example, when a film such as an aluminum foil is laminated, the gas barrier property can be improved and the light shielding property can be imparted. In addition, when a layer made of an oxide such as titanium oxide, aluminum oxide, or silicon oxide is formed, the transparency of the flexible bag 2 can be maintained while improving the gas barrier property, and the internal visibility can be secured. Can do. In addition, when the soft bag 2 is a multilayer laminated body, it is preferable that the material which forms the inner surface part is the material mentioned above.
The thickness of the sheet material constituting the flexible bag 2 is appropriately determined according to the layer configuration and the characteristics of the material used (flexibility, strength, water vapor permeability, heat resistance, etc.), and is not particularly limited. However, usually, it is preferably about 100 to 500 μm, and more preferably about 200 to 360 μm.
Further, the volume of the infusion container 1 varies depending on the type of medicine stored therein, but it is usually preferable that the volume of the medicine chamber is about 50 to 5000 ml.

The drug container 3 with a discharge port function is for discharging a drug storage unit added to a drug (medicine solution) filled in the soft bag 2 and a drug solution in the soft bag.
As shown in FIGS. 2 to 7, 11, and 12, the medicine container 3 includes a medicine container main body 5 and a cylindrical portion 6. As shown in FIG. 1, the drug container 3 has a soft bag 2 and a cylindrical portion 6 of the drug container 3 inserted between sheet materials constituting the soft bag 2 and fused and fixed in a liquid-tight state. In addition, the operation part 55 of the medicine container 3 projects into the medicine chamber 11. The drug container body 5 of the drug container 3 is fixed to the cylindrical part 6. Specifically, the cylindrical portion 6 of the drug container 3 is liquid-tightly attached to the soft bag 2 by ultrasonic fusion, high-frequency fusion, thermal fusion, or the like. By attaching the drug container 3 through the cylindrical part 6 in this way, it is possible to prevent the influence of energy such as heat generated during fusion from reaching the drug 8 in the drug container 54.

The medicine container body 5 seals a cylindrical body 51 having a medicine storage part 54, a breakable part 56, and an operation part 55, and an opening of the tubular body 51, and connects a medical needle. A discharge port capable of (puncturing), a needle tube intrusion inhibiting member 7 accommodated in the cylindrical main body 51, and a medicine 8 filled in the cylindrical main body 51 are provided.
The discharge port includes a seal member 53 capable of connecting (puncturing) a medical needle tube and a cap member 52 for fixing the seal member 53 to the opening of the cylindrical main body 51. The cap member 52 has a fixing portion (flange portion 58) bonded to a fixing portion (flange portion 57) provided at the proximal end portion of the cylindrical main body portion 51 by ultrasonic fusion, high-frequency fusion, heat fusion. Fixed by wearing. The medicine storage portion 54 of the cylindrical main body 51 is preferably formed to be transparent so that the inside medicine can be seen. Moreover, although the chemical | medical agent storage part 54 of the cylindrical main-body part 51 may be a normal pressure, it is good also as a pressure reduction or a vacuum state. As described above, when the medicine container is in a reduced pressure or vacuum state, the effect of preventing degradation / degradation and the like of the medicine improves.
The medicine 8 to be stored may be any powder or granular solid or liquid. Drugs are formulated and dissolved in infusions. For example, antibiotics, vitamins (general vitamins), various amino acids, antithrombotics such as heparin, insulin, antitumor agents, analgesics, cardiotonics, statics Note: Anesthetic agents, anti-Parkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, antiviral agents, immunostimulants, and the like.
The distal end of the medicine storage portion 54 of the cylindrical main body 51 is closed by the proximal end portion of the operation portion 55. Further, the distal end portion of the medicine storage portion 54 of the cylindrical main body portion 51 is formed in a tapered distal end portion whose diameter is reduced toward the distal end direction, in other words, a truncated cone shape. The tip internal shape is not limited to the truncated cone shape, and may be a dome shape, a substantially hemispherical shape, a polygonal truncated cone shape, or the like. Further, the medicine storage portion 54 of the cylindrical main body 51 has substantially the same outer diameter except for the distal end portion, and a flange portion 57 protruding in an annular shape is provided at the proximal end.
Moreover, it is preferable that the capacity | capacitance of the chemical | medical agent storage part 54 is 1-30 ml. Moreover, it is preferable that the length of the chemical | medical agent storage part 54 is 20-70 mm.

  The breakable portion 56 is a thin fragile portion provided near the boundary between the medicine storage portion 54 and the operation portion 55. In the embodiment, the thin fragile portion (breakable portion) is formed by an annular groove formed on the outer surface of the distal end portion of the medicine storage portion 54. For this reason, when the operation part 55 is bent from the outside of the bag, the breakable part 56 is cut and the operation part 55 is separated from the medicine storage part 54. The groove forming portion has a V-shaped cross section. Specifically, the cross-sectional V-shaped angle of the groove forming portion is preferably 30 to 90 °, particularly 40 to 50 °. By producing the groove forming portion at such an angle, when the operation portion 55 is bent, the stress is concentrated at the center of the breakable portion, so that the portion is reliably broken. The groove forming portion may have any shape as long as it can be easily broken, and is not limited to the V shape as in the embodiment, and may be a semicircular shape, a semielliptical shape, or the like. Moreover, it is good also as making it easy to fracture | rupture by producing the thickness of a groove formation part relatively thinner than the thickness of the groove formation part vicinity. Further, the breakable part may be made of a material more fragile than other parts. Specifically, it is preferable to make an annular shape with a material that can be easily broken only in the vicinity of the breakable portion by multicolor molding, and make the other portions with a material that is not easily broken. Further, in the embodiment of the present invention, the groove forming portion is an annular groove forming portion and is provided continuously around the entire outer peripheral surface of the medicine storage portion, but is not limited thereto, and may be provided intermittently. .

Moreover, it is preferable that the edge part by the side of the operation part 55 of the annular groove formation part which forms the fracture | ruptureable part 56 is chamfered. Specifically, it is preferable that the front end side outer surface edge portion is made to be rounded. For this reason, the cut and separated operation portion 55 prevents damage to a tubular flexible encapsulating portion 63 of the tubular portion 6 to be described later, particularly during a breaking operation.
The operation part 55 includes a plate-like main body part and a plurality of reinforcing parts 59 formed on both surfaces of the plate-like main body part perpendicular to the plate-like main body part along the axial direction. The reinforcing portion 59 is a grip portion that is gripped when performing a breaking operation, and has a thickness that decreases from the proximal end toward the distal end. Further, the operation portion 55 is hardly deformed in the bending direction by having the reinforcing portion, and the force applied during the breaking operation is surely concentrated on the breakable portion.
Moreover, it is preferable that the operation part in the vicinity of the breakable part where breakage is started does not substantially contact the reduced diameter tip part of the cylindrical part during the breaking operation of the operation part. Specifically, the operation unit 55 in the vicinity of the breakable part 56 for starting the break is the operation part on the side facing the fulcrum of the tip part of the tubular part 6 and the breakable part 56 during the breaking operation of the operation part 55. 55 is preferably substantially non-contacting. In the embodiment, since the gap is formed between the operation portion 55 side of the breakable portion 56 and the tip portion of the cylindrical portion, there is no contact.
Then, the breakable portion 56 starts the breaking operation with a point where the breakable portion 56 is located as a fulcrum by the rupture operation of the operation portion 55 and starts to break from the portion facing the fulcrum, and the breakable portion progresses. The operation portion 55 is preferably separated from the drug container main body portion 5 at the breakable portion 56 by the break operation progressing with the contact point between the operation portion 55 and the cylindrical portion 6 as a second fulcrum. .

Further, the operation portion 55 near the breakable portion 56 for starting breakage is a portion side facing the opening inner surface of the reduced diameter distal end portion 64 of the cylindrical portion 6 and the fulcrum of the breakable portion 56 during the breaking operation of the operation portion 55. It is preferable that the operation portion 55 is not substantially in contact. In the embodiment, since the gap is formed between the operation portion 55 side of the breakable portion 56 and the reduced diameter tip portion 64, there is no contact.
Further, the drug container body 5 and the cylindrical part 6 are formed by ultrasonic welding, heat-sealing, the distal end side surface of the flange part 57 of the drug container body part 5 and the proximal end side surface of the flange part 62 of the cylindrical part 6. Liquid-tight bonding is performed by high-frequency fusion or the like.
Further, in the drug container 3 with the discharge port function of this embodiment, as shown in FIGS. 2 to 5 and 7, a needle tube intrusion inhibiting member that inhibits the invasion of the medical needle tube is provided inside the drug container main body 5. 7 is stored. The needle tube entry inhibiting member 7 inhibits the medical needle tube from entering the drug container body 5 when the breakable portion 56 is not broken. As shown in FIGS. 9 and 10, the needle tube intrusion inhibiting member 7 in this embodiment includes a main body portion 71 having a distal end portion capable of coming into contact with the inside of the distal end portion of the cylindrical main body portion 51 of the drug container main body portion 5, and a medical device. And a proximal end portion 72 with which the distal end of the needle tube can abut.

When the breakable portion 56 of the medicine container 3 (the medicine container main body 5) is not broken (the state shown in FIGS. 1 to 4), when the medical needle tube is punctured into the seal member 53, the tip of the needle tube is the needle tube. It abuts against the base end portion 72 of the intrusion inhibiting member 7 to prevent entry. The operator can recognize that the breakable portion 56 of the drug container body 5 is not broken because the medical needle tube is not puncturable. The length of the medical needle tube that can be punctured into the drug container main body 5 when the breakable portion 56 of the drug container main body 5 is not broken is such that the opening of the medical needle tube does not communicate with the inside of the discharge port. Preferably there is.
In the needle tube penetration inhibiting member 7 of this example, the main body 71 has a cross-shaped cross section having plate-like portions 71a, 71b, 71c, 71d extending in the four axial directions as shown in FIGS. ing. Further, the base end portion 72 has a disk shape.
And this needle tube penetration | inhibition inhibiting member 7 can flow out from the chemical | medical agent container main-body part 5 after the fracture | rupture of the breakable part 56 of the chemical | medical-agent container main-body part 5 is fractured | ruptured. However, it is not limited to such a thing. The needle tube entry inhibiting member 7 is limited to the above-described needle tube entry inhibiting member as long as it restricts the puncture of the medical needle tube into the drug container main body 5 when the breakable portion 56 is not broken. It is not a thing.

The cylindrical portion 6 has a cylindrical shape with an opening at the distal end and a proximal end. The tubular portion 6 decreases in diameter toward the distal end, and encloses the breakable portion 56 and the proximal end portion 55 a of the operation portion 55. The reduced diameter distal end portion 64 and the reduced diameter distal end portion 64 are encapsulated, the proximal end portion of the operation portion 55 extending beyond the distal end of the reduced diameter distal end portion 64 and extending to the distal end side and exposed from the reduced diameter distal end portion 64 is covered. A cylindrical flexible encapsulating portion 63 that regulates contact of the breakable end portion 55b of the breakable portion 56 and the proximal end portion 55a of the operating portion 55 with the inner surface of the soft bag 2 during the breaking operation of the operating portion 55; It has. A flange portion 62 is provided at the proximal end portion of the cylindrical main body portion 61.
As shown in FIGS. 2 to 8, 11, and 12, the cylindrical portion 6 is a cylindrical body having an open front end and a base end. And the front-end | tip part of the cylindrical part 6 is the diameter-reduced front-end | tip part 64 which diameter-reduces, and encloses the breakable part 56, without contacting the breakable part 56 of the chemical | medical agent container main-body part 5. FIG. . Further, the distal end of the reduced diameter distal end portion 64 of the cylindrical portion 6 is located slightly closer to the operation portion side than the breakable portion 56, and the breakable portion 56 is broken when the breakable portion 56 is broken by the operation portion 55. The exposure from the cylindrical part 6 of a site | part is prevented.
Further, in the tubular portion of this embodiment, the reduced diameter tip portion 64 of the tubular portion 6 encloses the breakable portion 56 without contacting the breakable portion 56, and the breakable portion 56. When the outer diameter (or the outer diameter of the smallest outer diameter portion passing through the central axis of the drug container main body portion in the breakable portion 56) is Amm, the tip of the reduced diameter tip portion 64 of the cylindrical portion 6 can be broken. From the part 56, it is located in the 0.4Amm-Amm operation part 55 side. In particular, it is preferably located on the 0.5 Amm to 0.8 Amm operation unit 55 side. By having the above-described configuration, the soft bag is prevented from being damaged by the break end of the breakable portion during the break operation of the breakable portion of the drug container.

As shown in FIGS. 8 and 11, the cylindrical portion 6 includes a cylindrical main body portion 61 having substantially the same outer diameter, and a reduced diameter front end portion 64 that is reduced in a tapered shape provided at the front end of the cylindrical main body portion 61. And a cylindrical flexible envelope 63 extending in the distal direction from the vicinity of the central portion of the reduced diameter distal end portion 64, and a flange portion 62 provided at the proximal end portion of the cylindrical main body portion 61.
As shown in FIG. 11, the cylindrical flexible encapsulating portion 63 has a proximal end on the inclined surface of the reduced diameter distal end portion 64, and extends in the distal direction with substantially the same inner diameter. The cylindrical flexible encapsulating portion 63 extends beyond the distal end of the reduced diameter distal end portion 64, and includes a distal end portion of the reduced diameter distal end portion 64 and a proximal end portion of the operation portion 55 exposed from the reduced diameter distal end portion 64. Encapsulated. Further, there is a gap between the inner surface of the cylindrical flexible encapsulating portion 63, the distal end of the reduced diameter distal end portion 64, and the proximal end portion of the operation portion 55, and does not come into contact with both. Therefore, even if the operation portion 55 is deformed during the breaking operation of the operation portion 55, the break end 55b of the breakable portion 56 and the base end portion 55a of the operation portion 55 do not contact the inner surface of the flexible bag 2. Then, it comes into contact with the inner surface of the cylindrical flexible envelope 63.
And since the cylindrical flexible envelope part 63 has flexibility, it can deform | transform after contacting the operation part 55, Therefore The fracture | rupture operation of the operation part 55 is not inhibited. Therefore, the cylindrical flexible encapsulating portion 63 breaks the contact of the breakable end portion 55b of the breakable portion 56 and the proximal end portion 55a of the operation portion 55 with the inner surface of the flexible bag 2 during the breaking operation of the operation portion 55. Regulate without disturbing the operation. For this reason, the soft bag 2 is prevented from being damaged due to the breaking operation. As shown in FIGS. 8 and 11, in this embodiment, the cylindrical flexible envelope 63 is thinner toward the tip. Since the cylindrical flexible encapsulating portion 63 has a higher flexibility (in other words, soft) on the distal end side, the tubular flexible encapsulating portion 63 can be easily deformed after the contact of the fracture portion 55 and has a proximal end. Since the side is less flexible than the distal end side, in other words, is harder than the distal end side, even if it is strongly pressed by the break end 55b and the base end 55a of the operation portion 55 There is no breakage. The cylindrical flexible encapsulating part 63 is preferably cylindrical, but may be elliptical or polygonal. The tubular portion 6 is fixed to the soft bag 2 at the tubular main body 61 portion, and the tubular flexible encapsulating portion 63 is not fixed to the soft bag 2.

Furthermore, as shown in FIG. 5, the cylindrical portion 6 in this embodiment can be broken on the inner surface of the cylindrical portion 6 from the tip of the reduced diameter tip portion 64 of the cylindrical portion 6. A groove 64a extending to a position beyond the portion 56 is formed. In this embodiment, a plurality of grooves 64a are formed. By providing the groove 64a, the medicine can be discharged from the medicine container 3 when the breakable portion 56 of the medicine container 3 is broken. In particular, in the present invention, the reduced diameter distal end portion 64 of the cylindrical portion 6 is located at a position protruding from the breakable portion 56 by a predetermined distance. By forming this groove, the reduced diameter distal end portion of the tubular portion 6 is formed. 64 is reliably suppressed from becoming an obstacle to the discharge of the medicine.
The constituent materials of the drug container main body part 5, the cylindrical part 6, and the needle tube intrusion inhibiting member 7 are rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, cyclic polyolefin (specifically, ZEONEX (manufactured by ZEON Corporation), APEL (manufactured by Mitsui Chemicals), polypropylene homopolymer, polyolefin such as high density polyethylene, polystyrene, poly- (4-methylpentene-1), polycarbonate, ABS resin, acrylic resin, polymethyl methacrylate (PMMA), polyacetal , Polyesters such as polyarylate, polyacrylonitrile, polyvinylidene fluoride, ionomer, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate (PET), polybutylene terephthalate (PBT) Examples thereof include various resins such as butadiene-styrene copolymer, aromatic or aliphatic polyamide, or any combination thereof, and among these, the safety is high and the adhesiveness to the soft bag 2 is excellent. Of these, hard polyvinyl chloride, polyethylene, polypropylene and polyester are preferred.

Moreover, as a cylindrical part, the thing like the cylindrical part 6a with which the chemical | medical agent container 3a with a discharge port function of FIG. 13 is provided may be sufficient. The difference between the drug container 3a and the drug container 3 described above is only the shape of the cylindrical flexible encapsulating part 63a of the cylindrical part 6a.
The cylindrical portion 6a has a cylindrical shape with an open front end and a proximal end, and is reduced in diameter toward the tubular main body portion 61 and toward the distal end, and encapsulates the breakable portion 56 and the proximal end portion 55a of the operation portion 55. The reduced diameter distal end portion 64 and the proximal end portion of the operation portion 55 extending from the distal end portion of the reduced diameter distal end portion 64 and exposed from the reduced diameter distal end portion 64 are encapsulated, and the operation portion 55 is broken during the breaking operation. A tubular flexible encapsulating portion 63a for restricting contact of the break end 55b of the possible portion 56 and the base end portion 55a of the operation portion 55 to the inner surface of the soft bag 2 is provided. A flange portion 62 is provided at the proximal end portion of the cylindrical main body portion 61.
As shown in FIG. 13, the cylindrical portion 6 a is a cylindrical body having an open front end and a base end. And the front-end | tip part of the cylindrical part 6a is the diameter-reduced front-end | tip part 64 which diameter-reduces, and encloses the breakable part 56, without contacting the breakable part 56 of the chemical | medical agent container main-body part 5. FIG. . Further, the distal end of the reduced diameter distal end portion 64 of the cylindrical portion 6 a is located slightly closer to the operation portion side than the breakable portion 56, and the breakable portion 56 is broken when the breakable portion 56 is broken by the operation portion 55. The exposure from the cylindrical part 6a of a site | part is prevented. Also in the cylindrical portion 6 a of this embodiment, similarly to the cylindrical portion 6 described above, the reduced diameter tip portion 64 encapsulates the breakable portion 56 without contacting the breakable portion 56. .

  The cylindrical flexible encapsulating portion 63a has a proximal end near the distal end of the reduced diameter distal end portion 64, and extends so as to expand in a tapered shape toward the distal end side. The cylindrical flexible encapsulating portion 63 a extends beyond the distal end of the reduced diameter distal end portion 64, and includes a distal end portion of the reduced diameter distal end portion 64 and a proximal end portion of the operation portion 55 exposed from the reduced diameter distal end portion 64. Encapsulated. Further, there is a gap between the inner surface of the cylindrical flexible encapsulating portion 63a and the proximal end portion of the operation portion 55, so that they do not come into contact with each other. And even if the operation part 55 is deformed during the breaking operation of the operation part 55, the break end 55b of the breakable part 56 and the base end part 55a of the operation part 55 do not contact the inner surface of the soft bag 2. It comes into contact with the inner surface of the cylindrical flexible envelope 63a. And since the cylindrical flexible enveloping part 63a has flexibility, it can deform | transform after contacting the operation part 55, Therefore The fracture | rupture operation of the operation part 55 is not inhibited. Therefore, the cylindrical flexible encapsulating portion 63a breaks the contact of the breakable end portion 55b of the breakable portion 56 and the proximal end portion 55a of the operation portion 55 with the inner surface of the flexible bag 2 during the breaking operation of the operation portion 55. Regulate without disturbing the operation. For this reason, the soft bag 2 is prevented from being damaged due to the breaking operation. And as shown in FIG. 13, the cylindrical flexible envelope part 63a is thin toward the front-end | tip. For this reason, as for the cylindrical flexible covering part 63a, the front end side has higher flexibility. The cylindrical flexible encapsulating part 63a is preferably conical, but may be elliptical cone or polygonal cone.

The drug container with a discharge port function used in the infusion container of the present invention may be a drug container 3b with a discharge port function of the type shown in FIG. This medicine container 3b does not have the cylindrical portion 6 provided in the medicine container 3 described above.
The medicine container 3b in this embodiment is formed in a hollow medicine container 54 in which the medicine 8 is accommodated, and is breakable so that the medicine inside the medicine container 54 can be discharged by rupture formed on the distal end side of the medicine container 54. A drug container main body 5 a having a portion 56 and an operation portion 55 provided on the distal end side of the breakable portion 56 for performing a breaking operation of the breakable portion 56 is provided. The distal end portion of the medicine storage portion 54 is a reduced diameter portion 51 a that reduces the diameter toward the breakable portion 56. Further, the drug container main body 5a extends in the distal direction from the drug container 54, encloses the breakable portion 56 and the proximal end portion of the operation portion 55, and is separated from the proximal end portion, so that the operation portion 55 is being broken. A cylindrical flexible encapsulating portion 59 for restricting contact of the breakable end of the breakable portion 56 and the base end of the operation portion 55 to the inner surface of the soft bag 2 is provided.
And in the medicine container 3b, the medicine container main body part 5a, like the medicine container 5 described above, has a tubular body part 51 having a medicine storage part 54, a breakable part 56, and an operation part 55, and a tubular shape. The opening of the main body 51 is sealed, and a discharge port through which a medical needle can be connected (puncture), the needle tube entry inhibiting member 7 housed in the cylindrical main body 51, and the cylindrical main body 51 And a filled medicine 8. And the chemical | medical agent container main-body part 5a of this Example is provided with the cylindrical flexible encapsulation part 59. FIG. Further, the discharge port, the medicine storage portion 54, the breakable portion 56, the operation portion 55, and the needle tube entry inhibiting member 7 are the same as those described above.

The distal end of the medicine storage portion 54 of the cylindrical main body 51 is closed by the proximal end portion of the operation portion 55. Further, the distal end portion of the medicine storage portion 54 of the cylindrical main body portion 51 is a reduced diameter portion 51a that decreases in diameter toward the distal end direction. In other words, the distal end portion of the medicine storage portion 54 is formed in a truncated cone shape. The tip internal shape is not limited to the truncated cone shape, and may be a dome shape, a substantially hemispherical shape, a polygonal truncated cone shape, or the like. Further, the medicine storage portion 54 of the cylindrical main body 51 has substantially the same outer diameter except for the distal end portion, and a flange portion 57 protruding in an annular shape is provided at the proximal end.
The cylindrical flexible encapsulating portion 59 encapsulates the reduced diameter distal end portion 51a, further extends toward the distal end side, and encapsulates the proximal end portion of the operation portion 55. In addition, there is a gap between the inner surface of the cylindrical flexible encapsulating portion 59 and the proximal end portion of the operation portion 55, so that they do not contact each other. And even if the operation part 55 is deformed during the breaking operation of the operation part 55, the break end 55b of the breakable part 56 and the base end part 55a of the operation part 55 do not contact the inner surface of the soft bag 2. It comes into contact with the inner surface of the cylindrical flexible encapsulating portion 59. And since the cylindrical flexible envelope part 59 has flexibility, it can deform | transform after contacting the operation part 55, Therefore The fracture | rupture operation of the operation part 55 is not inhibited. The cylindrical flexible encapsulating part 59 is preferably cylindrical, but may be elliptical or polygonal. Furthermore, the cylindrical flexible enveloping portion 59 is conical like the cylindrical flexible enveloping portion 63a included in the cylindrical portion 6a shown in FIG. 13, and further has an elliptical cone shape and a polygonal pyramid shape. It may be.

Next, a method for using the infusion container 1 will be described with reference to the accompanying drawings.
FIG. 11 is a partially enlarged cross-sectional view of the vicinity of the reduced diameter tip portion of the cylindrical portion of the drug container 3 with a discharge port function used in the infusion container of the present invention. FIG. 12 is a cross-sectional view (during breakage) for explaining a method of using the infusion container according to the embodiment of the present invention.
The cylindrical part 6 of the medicine container 3 with the discharge port function is fixed with one hand, and the other hand is operated to grip and fold the operation part 55 through the soft bag 2. As shown in FIG. 12, the portion of the breakable portion 56 located on the folding direction side serves as a fulcrum, and the operation portion 55 rotates clockwise to face the portion of the breakable portion 56 opposite to the folding direction (facing the fulcrum). (Part) is started to break. Due to the start of the breakage, the medicine stored in the medicine container main body 5 flows through the space between the medicine container main body 5 and the cylindrical portion 6 and the groove 64a and flows into the medicine storage part 10 in the soft bag 2. Further, by proceeding with the breaking operation, the entire breakable portion 56 is broken. During the breaking operation of the breakable portion 56, the break end 55b formed by the breakage of the breakable portion 56 and the base end portion 55a of the operation portion 55 are located in the cylindrical flexible encapsulating portion 63, and the tube The base end portion 55a and the broken end 55b are not in contact with the inner surface of the soft bag 2, and the soft bag 2 is not damaged. Further, since the cylindrical flexible encapsulating portion 63 has flexibility, it does not hinder the breaking operation by the operation portion 55.

As an infusion container of the present invention, an embodiment in which a discharge port and a drug container are individually provided will be described.
FIG. 15 is a front view of an infusion container according to another embodiment of the present invention. 16 is an enlarged front view of a drug container used in the infusion container of FIG. 17 is a cross-sectional view of the drug container of FIG.
The infusion container 10 of this embodiment includes a soft bag 2 in which a chemical solution is stored, a hard drug container 9 that is attached to the soft bag 2 and stores a drug 98 for mixing with the chemical solution, and a discharge port 13. Prepare.
The discharge port 13 is a part for discharging the chemical solution. The discharge port 13 seals a cylindrical member having an open front end (lower side shown in FIG. 15) and a base end (upper side shown in FIG. 15), and a front end opening (mixed solution discharge port) on the front end side of the cylindrical member. An elastic member arranged in this manner and a cap (elastic member support member) for fixing the elastic member. The elastic member can pierce the needle tube, and can pierce the needle tube when necessary to infuse the mixed solution in the drug chamber 11.

As shown in FIGS. 16 and 17, the drug container 9 includes a drug container main body 15 and a cylindrical part 16. The medicine container 9 is attached to the soft bag 2 by a cylindrical portion 16. Specifically, the cylindrical portion 16 of the drug container 9 is liquid-tightly attached by a fixing portion 26 formed on the drug container fixing portion of the soft bag 2 by ultrasonic fusion, high-frequency fusion, heat fusion, or the like. Yes.
The drug container main body 15 includes a cylindrical main body 81 having a drug storage portion 84, a breakable portion 86, and an operation portion 85, and a lid portion 17 that seals an opening of the cylindrical main body 81. Yes. A flange portion 87 is provided at the proximal end portion of the cylindrical main body portion 81, and the flange portion 87 has a lid portion attachment portion that is manufactured in a concave shape and to which the lid portion 17 is attached. The lid is fixed in a liquid-tight manner to the lid mounting portion. Although the chemical | medical agent storage part 84 of the cylindrical main-body part 81 may be a normal pressure, it is good also as a pressure reduction or a vacuum state. As described above, when the medicine container is in a reduced pressure or vacuum state, the effect of preventing degradation / degradation and the like of the medicine improves.
As the medicine 98 to be stored, those described in the medicine 8 are preferably used.
The distal end of the medicine storage portion 84 of the cylindrical main body 81 is closed by the proximal end portion of the operation portion 85. Further, the distal end portion of the medicine storage portion 84 of the cylindrical main body portion 81 is formed in a tapered distal end portion whose diameter is reduced toward the distal end direction, in other words, a truncated cone shape. The tip internal shape is not limited to the truncated cone shape, and may be a dome shape, a substantially hemispherical shape, a polygonal truncated cone shape, or the like. Moreover, the medicine storage part 84 of the cylindrical main body part 81 has substantially the same outer diameter except for the distal end part, and a flange part 87 protruding in an annular shape is provided at the base end. Moreover, it is preferable that the capacity | capacitance of the chemical | medical agent storage part 84 is 1-30 ml. Moreover, it is preferable that the length of the chemical | medical agent storage part 84 is 20-70 mm.
Since the breakable portion 86 is the same as the breakable portion 56 described above, and the operation portion 85 is the same as the operation portion 55 described above, the above description is referred to.
Further, the drug container main body 15 and the cylindrical portion 16 are formed by ultrasonic bonding, heat fusing, and the distal end side surface of the flange portion 87 of the drug container main body portion 15 and the proximal end side surface of the flange portion 92 of the cylindrical portion 16. Liquid-tight bonding is performed by high-frequency fusion or the like.

The cylindrical portion 16 has a cylindrical shape with an open front end and a base end, and is reduced in diameter toward the cylindrical main body portion 91 and the front end to enclose the breakable portion 86 and the base end portion 85 a of the operation portion 85. The reduced diameter distal end portion 94 and the reduced diameter distal end portion 94 are encapsulated, the proximal end portion of the operation portion 85 extending beyond the distal end of the reduced diameter distal end portion 94 and extending to the distal end side and exposed from the reduced diameter distal end portion 94 is covered. A tubular flexible encapsulating portion 93 that regulates contact of the breakable end portion 86 of the breakable portion 86 and the proximal end portion 85a of the operation portion 85 to the inner surface of the soft bag 2 during the breaking operation of the operation portion 85. I have. A flange 92 is provided at the proximal end of the cylindrical main body 91.
As shown in FIGS. 16 and 17, the tubular portion 16 is a tubular body having an open front end and a base end. And the front-end | tip part of the cylindrical part 16 is the diameter-reduced front-end | tip part 94 which diameter-reduces, and envelops the breakable part 86, without contacting the breakable part 86 of the chemical | medical agent container main-body part 15. FIG. . Further, the distal end of the reduced diameter distal end portion 94 of the tubular portion 16 is located slightly closer to the operation portion side than the breakable portion 86, and the breakable portion 86 is broken when the breakable portion 86 is broken by the operation portion 85. The exposure from the cylindrical part 16 of a site | part is prevented.

As shown in FIGS. 16 and 17, the tubular portion 16 is substantially the same as the tubular portion 6 described above. For this reason, the cylindrical portion 16 includes a cylindrical main body portion 91 having substantially the same outer diameter, a reduced diameter distal end portion 94 that is provided at the distal end of the cylindrical main body portion 91, and a reduced diameter distal end portion 94. A cylindrical flexible enveloping portion 93 that extends in the distal direction from the vicinity of the central portion of the tube and a flange portion 92 provided at the proximal end portion of the cylindrical main body portion 91 are provided.
And the cylindrical flexible envelope part 93 has a base end in the inclined surface of the diameter-reduced front-end | tip part 94, and is extended in a front end direction with substantially the same internal diameter. The cylindrical flexible encapsulating portion 93 extends beyond the distal end of the reduced diameter distal end portion 94 and includes a distal end portion of the reduced diameter distal end portion 94 and a proximal end portion of the operation portion 85 exposed from the reduced diameter distal end portion 94. Encapsulated. Further, there is a gap between the inner surface of the cylindrical flexible encapsulating portion 93, the distal end of the reduced diameter distal end portion 94, and the proximal end portion of the operation portion 85, and does not come into contact with both. For this reason, even if the operation portion 85 is deformed during the breaking operation of the operation portion 85, the break end of the breakable portion 86 and the base end portion of the operation portion 85 are not in contact with the inner surface of the flexible bag 2. It comes into contact with the inner surface of the flexible envelope portion 93. And since the cylindrical flexible envelope part 93 has flexibility, it can deform | transform after contacting the operation part 85, Therefore The fracture | rupture operation of the operation part 85 is not inhibited. Therefore, the tubular flexible encapsulating portion 93 allows the breaking operation to be performed by contacting the breaking end of the breakable portion 86 and the base end portion of the operating portion 85 to the inner surface of the flexible bag 2 during the breaking operation of the operation portion 85. Regulate without hindering. For this reason, damage to the soft bag 2 resulting from the breaking operation is prevented. And in the thing of this Example, the cylindrical flexible encapsulation part 93 is thin toward the front-end | tip. For this reason, since the cylindrical flexible enveloping part 93 has higher flexibility (in other words, softness) on the tip side, it can be easily deformed after contact with the operation part 85. The base end side is less flexible than the front end side (harder than the front end side), so that it breaks even if it is strongly pressed by the break end and base end portion of the operation portion 85. There is nothing. Further, the cylindrical flexible encapsulating portion 93 is preferably cylindrical, but an elliptical cylindrical shape, a polygonal cylindrical shape, and the cylindrical portion 6a of the drug container 3a shown in FIG. 13 and described above are provided. Further, it may be a conical shape whose diameter is increased in a tapered shape, or an elliptical cone shape or a polygonal pyramid shape.

Also in the cylindrical portion 16 in this embodiment, as shown in FIG. 5, the inner surface of the cylindrical portion 16 is provided with a reduced diameter tip portion 94 of the cylindrical portion 16 as in the above-described cylindrical portion 6. You may have a groove | channel extended from the front-end | tip to the position beyond the breakable part 86 of the chemical | medical agent container main-body part 15. As shown in FIG.
Further, in the infusion container in this embodiment, the drug container does not have the above-described cylindrical part as shown in FIG. 14, and the drug container main body part extends in the distal direction from the drug storage part, and the breakable part and A cylindrical flexible enveloping part that encloses the base end part of the operation part and regulates the breakable end of the breakable part during the breaking operation of the operation part and the contact of the base end part of the operation part to the inner surface of the soft bag May be provided.
The constituent materials of the drug container main body 15, the cylindrical portion 16, and the lid portion 17 are rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, cyclic polyolefin [specifically, ZEONEX (manufactured by Zeon Corporation), APEL ( Manufactured by Mitsui Chemicals, Inc.), polypropylene homopolymer, polyolefin such as high-density polyethylene, polystyrene, poly- (4-methylpentene-1), polycarbonate, ABS resin, acrylic resin, polymethyl methacrylate (PMMA), polyacetal, Polyarylate, polyacrylonitrile, polyvinylidene fluoride, ionomer, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate (PET), polyester such as polybutylene terephthalate (PBT), Diene - styrene copolymer, various resins such as aromatic or aliphatic polyamide, or is a combination thereof any thereof. Among these, hard polyvinyl chloride, polyethylene, polypropylene, and polyester are preferable because they are highly safe and have excellent adhesion to the soft bag 2.

The infusion container of the present invention may be of a type such as an infusion container 20 as shown in FIG.
FIG. 18 is a front view of an infusion container according to another embodiment of the present invention.
The medical container 20 of this embodiment is made of a flexible material, and is a soft bag (container main body) divided into a first drug chamber 101 and a second drug chamber 102 by a partitioning portion 109 whose internal space can be peeled off. ) 2, the medicine container 3 with the discharge port function fixed to the first medicine chamber 101 side, the mixed injection port 18 fixed to the second medicine chamber 102 side, and the first medicine chamber 101. The first medicine and the second medicine housed in the second medicine chamber 102 are provided. Furthermore, the medical container 20 of this embodiment includes a peelable communication inhibition weak seal portion 106 that inhibits communication between the first drug chamber 101 and the discharge port (drug container) 3.
As the medicine container 3 with the discharge port function, those described above are preferably used. A known port can be used as the mixed injection port 18.
The flexible bag 2 is formed of a sheet-like cylindrical body, and has a partition 109 that partitions the storage, and the storage is partitioned into a first drug chamber 101 and a second drug chamber 102. ing. Furthermore, the medical container 20 includes a peelable communication hindering seal portion 106 formed to enclose the upper portion of the operation portion 55 of the medicine container 3 with the discharge port function. The soft bag 2 is the same as the soft bag described above, except for the partition portion 109 and the communication inhibition weak seal portion 106.
In this embodiment, the communication inhibition weak seal portion 106 is formed so as to surround the medicine container 3 with the discharge port function. A third chamber 107 isolated from the first drug chamber 101 is formed by the communication inhibition weak seal portion 106. The third chamber 107 is an empty room. However, a predetermined liquid (for example, physiological saline) may be placed in the third chamber. The third chamber may be in a dry state, but may be filled with a small amount of liquid for sterilization. Further, a passage through which some water vapor or medicine passes through the communication inhibition weak seal portion 106 may be formed so as to communicate with the first medicine chamber 101 at the above level. The communication inhibition weak seal portion 106 can be formed by heat-sealing a sheet material in a band shape (thermal fusion, high-frequency fusion, ultrasonic fusion, etc.).

In the embodiment shown in FIG. 18, the communication hindering weak seal portion 106 is formed in a trapezoidal shape with the short side on the upper side. In addition, the weak seal part for communication inhibition is an inverted U-shape, a trapezoidal shape with the short side on the lower side, a triangular shape with the discharge port at the top, a triangular shape with the discharge port at the bottom, a polygonal shape such as a square shape, etc. A substantially semicircular shape or a substantially semielliptical shape may be used. Further, the sealing strength of the communication hindering weak seal portion 106 is preferably the same as, slightly larger or slightly smaller than the sealing strength of the partitioning portion (weak partitioning seal portion) 109. If it is such, a chemical | medical solution will not be administered in the state where the partition part 109 is not peeled, and administration preparation can be performed by easy operation.
Further, the communication inhibition weak seal portion 106 is peeled off from the communication inhibition weak seal portion 106 almost simultaneously with or subsequently to the separation of the partition 109 by pressing the first drug chamber 101 or the second drug chamber 102. It is preferable that
And in the medical container 1 of this Example, as shown in FIG. 18, the two opposing side protrusion seal parts 110 extended in the center direction of the soft bag 2 from the side center part of the soft bag 2 are provided. The partition part 109 is connected to the two side projecting seal parts 110 and is provided so as to cross the entire lateral direction of the drug chamber of the soft bag 2. The partition portion 109 is a peelable seal portion, in other words, a weak seal portion.

DESCRIPTION OF SYMBOLS 1 Infusion container 2 Soft bag 3 Drug container with discharge port function 5 Drug container main-body part 55 Operation part 56 Breakable part 6 Cylindrical part 63 Cylindrical flexible encapsulation part 64 Reduced diameter front-end | tip part

Claims (12)

An infusion container comprising a soft bag containing a drug solution and a hard drug container attached to the soft bag and containing a drug for mixing with the drug solution, wherein the drug container stores the drug A hollow medicine storage portion formed on the front end side of the medicine storage portion, a breakable portion capable of discharging the medicine inside the medicine storage portion by breakage, and a breakable portion provided on the front end side from the breakable portion A medicine container main body having an operation part for performing a breaking operation of the part, and a cylindrical shape that coaxially encapsulates the breakable part at the tip and fixed to the medicine container main body or the soft bag The cylindrical portion is reduced in diameter toward the distal end, and the reduced diameter distal end portion enveloping the breakable portion and the proximal end portion of the operation portion, and the distal end side from the reduced diameter distal end portion And exposed from the tip of the reduced diameter A cylindrical shape that encapsulates a base end portion of the operation portion and restricts contact between the breakable end of the breakable portion and the base end portion of the operation portion on the inner surface of the soft bag during the breaking operation of the operation portion An infusion container comprising a flexible encapsulating part. The cylindrical flexible encapsulating portion encloses the reduced diameter tip portion, and further extends beyond the distal end of the reduced diameter tip portion to the distal end side, and is exposed from the reduced diameter tip portion. The infusion container according to claim 1, which encapsulates the proximal end portion. The infusion container according to claim 1 or 2, wherein the cylindrical flexible encapsulating portion extends at substantially the same inner diameter or extends so as to expand in a tapered shape. The breakable portion starts the breaking operation with a breakable portion of the operation portion as a fulcrum by a breaking operation of the operation portion, starts to break from the portion facing the fulcrum, and the breakage of the breakable portion progresses. The operation portion is separated from the drug container main body portion at the breakable portion by the break operation proceeding with a contact point between the operation portion and the reduced diameter tip portion of the cylindrical portion as a second fulcrum. The infusion container according to any one of claims 1 to 3. The said cylindrical part is being fixed to the said chemical | medical agent container main-body part and the said soft bag, and the said chemical | medical agent container main-body part is attached to the said soft bag via the said cylindrical part. A container for infusion according to crab. The groove | channel extended from the said front-end | tip of this reduced diameter front-end | tip part to the position beyond the said fracture | ruptureable part of the said chemical | medical agent main-body part is formed in the inner surface of the said diameter-reduced front-end | tip part of the said cylindrical part. The infusion container according to any one of 5. An infusion container comprising a soft bag containing a drug solution and a hard drug container attached to the soft bag and containing a drug for mixing with the drug solution, wherein the drug container stores the drug A hollow medicine storage portion formed, a breakable portion formed on the distal end side of the medicine storage portion and capable of discharging the medicine inside the medicine storage portion by breakage, and provided on the distal end side from the breakable portion, A medicine container main body having an operation part for performing a breaking operation of the breakable part, and the distal end part of the medicine storage part is a reduced diameter part that reduces the diameter toward the breakable part, The drug container main body extends from the drug container to the distal end side, encloses and separates the breakable portion and the proximal end portion of the operation portion, and breaks the breakable portion during the break operation of the operation portion Of the end and the base end of the operation unit Fluid vessel, characterized in that it comprises a tubular flexible encapsulation portion for restricting contact to the inner surface of serial soft bag. The infusion container according to claim 7, wherein the cylindrical flexible encapsulating portion extends at substantially the same inner diameter or extends so as to expand in a tapered shape. The infusion container according to any one of claims 1 to 8, wherein the cylindrical flexible encapsulating portion is thinner toward the tip. The infusion port according to any one of claims 1 to 9, wherein the medicine container is a discharge port that seals an opening of the medicine container body and has a sealing part that can be connected to a medical needle tube. container. The needle tube intrusion inhibiting member that inhibits intrusion of the medical needle tube into the drug container main body when the breakable portion is not broken is housed in the drug container main body. Infusion container. The infusion container according to any one of claims 1 to 9, wherein the infusion container includes a discharge port for discharging the drug solution in the soft bag or a mixed solution of the drug solution and the drug.

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