JP5450207B2 - Hollow body for medical container, discharge port for medical container, drug container for medical container, and medical container - Google Patents

Description

  TECHNICAL FIELD The present invention relates to a medical container and a medical container hollow body, a medical container discharge port, and a medical container drug container that can adjust and blend a drug in a drug solution such as an infusion solution. .

The medical container has a closed tip and a cylindrical body that can be opened. Examples of the cylindrical body include a discharge port used at the time of administration of a drug solution and a drug container that stores a drug added to the drug solution in the medical container.
Prior to infusion of the patient, mix and dissolve drugs that are difficult to pre-mix into the infusion, such as vitamins and antibiotics, in a vial or soft bag containing the infusion. The preparation of chemicals has been carried out. In order to prepare such a chemical solution aseptically and with a simple operation, a drug container containing a drug to be mixed with the chemical solution is attached to a soft bag containing the chemical solution, There has been proposed a medical container in which a drug container and a soft bag are communicated to mix a drug and a drug solution by bending and breaking the provided weak part through a soft bag.

The present applicant has proposed JP-A-2006-87904 (Patent Document 1).
The drug container or discharge port of Patent Document 1 is a drug container or discharge port that can be opened and has a closed tip, and can reliably separate the drug container or discharge port from the medical container. In addition, the medicine container or the discharge port can be communicated with the medical container easily and reliably when necessary. As shown in FIGS. 32 to 37, the drug container 100 of Patent Document 1 is formed of a hard or semi-rigid material, and further has a cylindrical portion 7 with a closed end portion, and at least the distal end of the cylindrical portion 7. The first stress applying portion 59 and the soft bag that are provided so as to sandwich the breakable portion 58 provided in the portion and the breakable portion 58 of the tubular portion 7 and are fixed to one inner surface of the soft bag 2 2 and the second stress applying portion 60 fixed to the other inner surface, and the breakable portion 58 can be broken and broken by spreading between the first stress applying portion 59 and the second stress applying portion 60. The front end side portion is separated from the portion 58 and the cylindrical portion 7 is opened.

Further, as shown in FIGS. 38 to 42, the discharge port 86 of Patent Document 1 is formed of a hard or semi-rigid material, and further includes a cylindrical portion 88 whose tip is closed, and a cylindrical portion 88. A first stress applying portion 89 which is provided so as to sandwich at least the breakable portion 91 provided at the tip portion and the breakable portion 91 of the tubular portion 88 and is fixed to one inner surface of the soft bag 2; A second stress applying portion 90 fixed to the other inner surface of the soft bag 2, and the breakable portion 91 is broken by the spread between the first stress applying portion 89 and the second stress applying portion 90. The front end side portion is separated from the breakable portion 91 and the cylindrical portion 88 is opened.
However, as shown in FIG. 29 of Patent Document 1, the breakable portion 58 or the discharge port 86 of the drug container 100 is pressed by pressing the soft bag 2 of the medical container 1 and 85 including the drug container 100 and the discharge port 86. When the breakable portion 91 is broken and the first stress applying portion side portion and the second stress applying portion side portion are separated from the breakable portions 58, 91, the opening of the tubular portion formed by the break is formed. Although rare, it is feared that it will be blocked again by the separated member.
Therefore, the present applicant has proposed JP-A-2006-280390 (Patent Document 2).
The medical container of Patent Document 2 is a medical container 1 including a soft bag 2 having a drug room, a chemical solution, and a cylindrical body, and the cylindrical body includes a cylindrical portion, a breakable portion, The first and second stress applying portions 34 and 36 are provided so as to sandwich the breakable portion and fixed to the inner surface of the soft bag, and the breakable portion includes first and second stress applying portions 34, It breaks and opens due to the spread of 36. Further, the container 1 extends to the distal end side so as to get over the outer surface of the proximal end portion of the breakable portion, and the proximal end portion 33a of the first stress applying portion side separating portion 33 and the second stress applying portion side separation after the breaking. An extension portion for holding a post-breaking stress applying portion that holds the base end portion 35a of the portion 35 between the inner surface of the soft bag is provided.

JP 2006-87904 A JP 2006-280390 A

Even the thing of the patent document 2 mentioned above has a sufficient effect, but the base end part 33a of the first stress applying part side separating part 33 after breaking and the base end part 35a of the second stress applying part side separating part 35 are provided. In some rare cases, the holding state may be released during the operation of holding the post-breaking stress applying part holding extension part and then hanging it on the stand.
Therefore, the present invention solves the above-described problems, a cylindrical portion whose tip is closed, a breakable portion provided at least at the tip of the cylindrical portion, and a breakable portion of the cylindrical portion A first stress applying portion fixed to one inner surface of the soft bag and a second stress applying portion fixed to the other inner surface of the soft bag, and A hollow body for a medical container having a breakable portion that is broken by spreading between the stress applying portion and the second stress applying portion, wherein the opening formed by the breakage of the breakable portion is separated from the cylindrical member. Hollow body for medical container that is very unlikely to be closed again by one stress applying part or second stress applying part, medical container drug container using the same, medical container discharge port and medical container Is to provide

What achieves the above object is as follows.
(1) A hollow body for a medical container used for a medical container including a soft bag, the hollow body being formed of a hard or semi-rigid material, and the distal end of the hollow body being closed A cylindrical portion, a breakable portion provided at a tip portion of the cylindrical portion, and an inner surface of one sheet of the flexible bag that are provided so as to sandwich the breakable portion of the cylindrical portion. And a second stress applying part that can be fixed to the inner surface of the other sheet of the soft bag, and the breakable part includes the first stress applying part and the first stress applying part. The first stress applying part or the second stress applying part includes a first engaging part, and is broken by spreading between two stress applying parts. The cylindrical portion includes the first stress applying portion and the second stress applying portion. The breakable portion is broken by spreading between the stress applying portions, and after the opening of the cylindrical portion, the first engaging portion is engaged with the first stress applying portion or the second stress applying portion. The hollow body for medical containers which has a 2nd engaging part holding a part.

Moreover, what achieves the said objective is as follows.
(2) A hollow body for a medical container used for a medical container provided with a soft bag, the hollow body being formed of a hard or semi-rigid material, and the distal end of the hollow body being closed A cylindrical portion, a breakable portion provided at a tip portion of the cylindrical portion, and an inner surface of one sheet of the flexible bag that are provided so as to sandwich the breakable portion of the cylindrical portion. A second stress applying portion capable of being fixed to the inner surface of the other sheet of the soft bag, and a cylindrical member provided so as to enclose the cylindrical portion, The breakable portion breaks due to the spread between the first stress applying portion and the second stress applying portion, and opens the cylindrical portion. The first stress applying portion or the first stress applying portion The second stress applying portion includes a first engaging portion, The tubular member breaks the breakable portion by spreading between the first stress applying portion and the second stress applying portion, and engages with the first engaging portion after opening the cylindrical portion. And a hollow body for a medical container having a second engaging portion that holds the first stress applying portion or the second stress applying portion.

(3) The medical container hollow according to (1) or (2), wherein the first engagement portion and the second engagement portion are provided so as to face each other via the breakable portion. body.
(4) One of the first engaging portion and the second engaging portion is a protrusion, and the other is a protruding portion having a claw portion engaging with the protrusion at a tip portion. Thru | or the hollow body for medical containers in any one of (3).
(5) One of the first engaging portion and the second engaging portion is a protrusion having a through hole, and the other is a protruding portion having a tip portion that enters and engages in the through hole. The medical container hollow body according to any one of the above (1) to (3).
(6) The first engagement portion is a protrusion, and the second engagement portion is provided at a distal end portion of the cylindrical member, and is formed by a recess that engages with the protrusion. The hollow body for medical containers as described in 2).
(7) The first stress applying part and the second stress applying part include a flat part for fixing to the inner surface of the soft bag, and the first engaging part and the second engaging part. The hollow body for medical containers according to any one of the above (1) to (6), which is formed so as to be positioned on an extension line in the axial direction of the hollow body for medical containers of the flat portion.

Moreover, what achieves the said objective is as follows.
(8) The medical container hollow body according to any one of (1) to (7) above, and the medical container hollow body having an open rear end, and the rear end of the hollow body. A discharge port for a medical container having a sealing portion that can be sealed and connected to a medical needle tube.
(9) The medical container discharge port according to (8), wherein a medicine is stored in the cylindrical member of the medical container discharge port.
(10) The hollow body of the discharge port for the medical container stores a medicine and a needle tube intrusion inhibiting member that inhibits the medical needle tube from entering the hollow body when the breakable portion is not broken. The discharge port for medical containers according to the above (9).

Moreover, what achieves the said objective is as follows.
(11) The medical container hollow body according to any one of (1) to (7), wherein the medical container hollow body having one end opened and the one end of the hollow body sealed. A medical container for a medical container having a sealing member and a medicine stored in the hollow body.

Moreover, what achieves the said objective is as follows.
(12) A medical container comprising a soft bag, a drug chamber formed in the soft bag, a drug solution filled in the drug chamber, and a discharge port attached to the soft bag, wherein the discharge The port is the discharge port according to any one of the above (8) to (10), and a part of the outer surface of the first stress applying part forms one sheet of the soft bag in the medicine chamber A part of the outer surface of the second stress applying portion is fixed to the inner surface of the other sheet forming the drug chamber of the soft bag, and the breakable portion is Medical use that breaks due to expansion of the first stress applying portion and the second stress applying portion fixed to the soft bag when the drug chamber is pressed, and makes the inside of the discharge port communicate with the drug chamber container.

Moreover, what achieves the said objective is as follows.
(13) A soft bag, a drug chamber formed in the soft bag, a drug solution filled in the drug chamber, a drug container that is attached to the soft bag and contains a drug for mixing with the drug solution, And a discharge container attached to the soft bag, wherein the drug container is the drug container described in (11) above, and one of the outer surfaces of the first stress applying part. The part is fixed to the inner surface of one sheet forming the drug chamber of the soft bag, and a part of the outer surface of the second stress applying part is the other sheet forming the drug chamber of the soft bag The breakable portion is broken by the spread of the first stress applying portion and the second stress applying portion fixed to the soft bag when the drug chamber is pressed, Inside the drug container, the drug chamber A medical container that communicates with a medical device.

  The hollow body for medical containers of this invention is a hollow body for medical containers used for a medical container provided with a soft bag. The hollow body is made of a hard or semi-rigid material, and the hollow body has a cylindrical portion with a closed end, a breakable portion provided at the distal end of the tubular portion, and a breakable portion of the tubular portion. A first stress applying portion that can be fixed to one inner surface of the soft bag and a second stress applying portion that can be fixed to the other inner surface of the soft bag. The breakable part breaks due to the spread between the first stress applying part and the second stress applying part, and opens the cylindrical part. The first stress applying part or the second stress applying part includes the first engaging part, and the cylindrical member provided so as to enclose the cylindrical part or the cylindrical part has the first stress. The breakable portion breaks due to the spread between the applying portion and the second stress applying portion, and after the opening of the tubular portion, the first engaging portion is engaged with the first stress applying portion or the second stress. It has the 2nd engaging part holding a grant part. For this reason, according to this hollow body for medical containers, the first stress applying part and the second stress applying part are expanded, and after the breakable part is broken, the first stress applying part and the second stress are applied. Since the state where the space between the applying portions is expanded is maintained, the opening formed by the breakage of the breakable portion is reliably prevented from being closed again by the first stress applying portion and the second stress applying portion.

FIG. 1 is a front view of an embodiment of the medical container of the present invention. FIG. 2 is a front view of an embodiment of the medical container discharge port of the present invention. FIG. 3 is a cross-sectional view taken along line AA in FIG. 4 is an enlarged sectional view taken along line BB in FIG. FIG. 5 is a right side view of one embodiment of the medical container hollow body of the present invention. FIG. 6 is a right side view of the hollow body for a medical container shown in FIG. FIG. 7 is a perspective view of the hollow body for a medical container shown in FIG. FIG. 8 is an enlarged plan view of the hollow body for a medical container shown in FIG. FIG. 9 is an enlarged view of the vicinity of the first engagement portion and the second engagement portion of the medical container hollow body shown in FIG. 5. FIG. 10 is a front view of an example of a needle tube entry inhibiting member housed in the medical container discharge port of the present invention. FIG. 11 is an enlarged plan view of the needle tube entry inhibiting member shown in FIG. FIG. 12 is an enlarged bottom view of the needle tube entry inhibiting member shown in FIG. FIG. 13 is a perspective view of the needle tube penetration inhibiting member shown in FIG. FIG. 14 is a perspective view of a hollow body attaching member used in the medical container of the present invention. FIG. 15 is an explanatory view for explaining the action of the medical container hollow body of the present invention and the medical container discharge port using the same. FIG. 16 is an explanatory diagram for explaining the operation of the medical container of the present invention. FIG. 17 is a side view of another embodiment of the medical container hollow body of the present invention. FIG. 18 is a perspective view of the hollow body for a medical container shown in FIG. FIG. 19 is an enlarged plan view of the medical container hollow body shown in FIG. 17. FIG. 20 is an enlarged view of the vicinity of the first engaging portion and the second engaging portion of the medical container hollow body shown in FIG. 17. FIG. 21 is an explanatory diagram for explaining the operation of the medical container hollow body shown in FIGS. 17 to 19 and the medical container discharge port using the same. FIG. 22 is a perspective view of another embodiment of the medical container discharge port of the present invention. FIG. 23 is a side view of a medical container hollow body used for the medical container discharge port shown in FIG. 22. FIG. 24 is an enlarged plan view of the hollow body for a medical container shown in FIG. FIG. 25 is an enlarged cross-sectional view of the vicinity of the first engaging portion and the second engaging portion of the medical container hollow body shown in FIG. FIG. 26 is an explanatory diagram for explaining the operation of the medical container hollow body shown in FIGS. 22 to 24 and the medical container discharge port using the same. FIG. 27 is an explanatory diagram for explaining the operation of the medical container hollow body shown in FIGS. 22 to 24 and the medical container discharge port using the same. FIG. 28 is a front view of another embodiment of the medical container discharge port of the present invention. 29 is a cross-sectional view taken along the line CC of FIG. FIG. 30 is an enlarged front view of a cylindrical member provided in the medical container hollow body of the medical container discharge port shown in FIG. 28. 31 is a perspective view of the tubular member shown in FIG. FIG. 32 is a side view of the medical container hollow body (with the tubular member removed) used in the medical container discharge port shown in FIG. FIG. 33 is a perspective view of the medical container hollow body shown in FIG. 28 (with the tubular member removed). FIG. 34 is an explanatory diagram for explaining the operation of the medical container discharge port shown in FIG. FIG. 35 is an explanatory diagram for explaining the operation of the medical container discharge port shown in FIG. 28. FIG. 36 is a front view of another embodiment of the medical container of the present invention. FIG. 37 is a front view of an embodiment of a medical container for medical containers of the present invention. 38 is a cross-sectional view taken along the line EE of FIG. FIG. 39 is an enlarged cross-sectional view of the vicinity of the first engagement portion and the second engagement portion of the medical container hollow body used in the medical container drug container shown in FIG. 37. FIG. 40 is a cross-sectional view of another embodiment of the medical container for medical containers of the present invention. 41 is an enlarged cross-sectional view of the medical container hollow body used in the medical container drug container shown in FIG. 40 in the vicinity of the first engagement portion and the second engagement portion. FIG. 42 is a cross-sectional view of another embodiment of the medical container for medical containers of the present invention. 43 is an enlarged cross-sectional view of the medical container hollow body used in the medical container drug container shown in FIG. 42 in the vicinity of the first engagement portion and the second engagement portion. FIG. 44 is a cross-sectional view of another example of the medical container for medical container of the present invention. 45 is an enlarged cross-sectional view of the vicinity of the first engagement portion and the second engagement portion of the medical container hollow body used in the medical container drug container shown in FIG. 44. FIG. 46 is a front view of another embodiment of the medical container of the present invention. FIG. 47 is a front view of another embodiment of the medical container of the present invention. FIG. 48 is a front view of another embodiment of the medical container of the present invention. FIG. 49 is a front view of another embodiment of the medical container discharge port of the present invention. FIG. 50 is a right side view of another embodiment of the hollow body for a medical container of the present invention. 51 is a perspective view of the medical container hollow body shown in FIG. 50. FIG. FIG. 52 is a front view of another embodiment of the medical container for medical containers of the present invention. 53 is an enlarged cross-sectional view of the vicinity of the first engagement portion and the second engagement portion of the medical container hollow body used in the medical container pharmaceutical container shown in FIG. 52. FIG.

The hollow body for medical containers, the medicine container for medical containers, the discharge port for medical containers, and the medical container of the present invention will be described with reference to the embodiments shown in the drawings.
The medical container hollow body 30 of the present invention is a medical container hollow body used for the medical container 1 including the soft bag 2. The hollow body 30 is formed of a hard or semi-rigid material, and further, the hollow body 30 includes a cylindrical portion 31 whose tip is closed, and a breakable portion 36 provided at the tip of the cylindrical portion 31. The first stress applying portion 34 that is provided so as to sandwich the breakable portion 36 of the tubular portion 31 and can be fixed to the inner surface of one sheet 2a of the soft bag 2 and the inner surface of the other sheet 2b of the soft bag 2 And a second stress applying portion 35 that can be fixed to the head. The breakable portion 36 breaks due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and opens the tubular portion 31. Further, the first stress applying part 34 or the second stress applying part 35 includes a first engaging part 37, and a cylindrical part 31 (or a cylindrical member provided so as to enclose the cylindrical part). The breakable portion 36 is broken by the spread between the first stress applying portion 34 and the second stress applying portion 35, and after the opening of the tubular portion 31, the first engaging portion 37 is engaged, It has a second engaging portion 38 that holds the first stress applying portion 34 or the second stress applying portion 35.
Then, when the first engaging portion 37 and the second engaging portion 38 are engaged, the cylindrical portion (or the cylindrical member) becomes the first stress applying portion 34 or the second stress applying portion 35. Thus, the opening state of the cylindrical portion 31 is maintained.

Moreover, the discharge port 3 for medical containers of this invention is the hollow body for medical containers of this invention, and the rear end part of the hollow body 30 which the rear-end part opened, and the rear-end part of the hollow body 30 is sealed, and medical And a sealing portion capable of connecting a needle tube.
The medical container 7 for medical containers of the present invention includes a hollow body 70 for medical containers of the present invention, a sealing member 72 that seals the opening of the hollow body 70, and a drug 73 stored in a cylindrical portion. It has.
The medical container 1 of the present invention includes a soft bag 2, a drug room (specifically, a drug room) 11 formed in the soft bag 2, a drug solution filled in the drug room 11, and a soft bag. 2 and a discharge port 3 attached to 2. And as the discharge port 3, the discharge port using the hollow body for medical containers of this invention is used.
The medical container 40 according to the present invention includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and the drug bag 11 attached to the soft bag 2. A drug container 7 containing a drug for mixing with a drug solution and a discharge port 10 attached to the soft bag 2 are provided. And as the medicine container 7, the medicine container 7 using the hollow body for medical containers of the present invention is used.

First, a medical container hollow body according to the present invention applied to a medicine container / discharge port and a medical container using the same will be described.
The medical container 1 of this embodiment includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a discharge port 3 attached to the soft bag 2. Prepare. The discharge port 3 is a discharge port using the medical container hollow body of the present invention, and a part of the outer surface of the first stress applying portion 34 forms the drug chamber 11 of the soft bag 2. A part of the outer surface of the second stress applying portion 35 is fixed to the inner surface of the other sheet 2b forming the drug chamber 11 of the soft bag 2, and the breakable portion 36 is fixed to the inner surface of the second sheet 2a. Is broken by the expansion of the first stress applying portion 34 and the second stress applying portion 35 fixed to the soft bag 2 when the drug chamber 11 is pressed, and the inside of the discharge port 3 is communicated with the drug chamber 11. is there.
The medical container 1 of this embodiment is formed of a flexible material, and includes a soft bag 2 having a drug chamber 11 serving as a drug storage portion therein, and a medical container attached to the drug chamber 11 of the soft bag 2. It is a medical container containing a medicine provided with a discharge port 3 and a medicine liquid filled in the medicine chamber 11.
As shown in FIG. 1, seal portions 5 and 6 are provided on one end side and the other end side of the soft bag 2.

The soft bag 2 of the medical container 1 is made of a soft synthetic resin. The flexible bag 2 is preferably formed into a cylindrical shape by an inflation molding method. The soft bag 2 may be manufactured by various methods such as a blow molding method and a coextrusion inflation method.
The soft bag 2 preferably has a water vapor barrier property. As the degree of water vapor barrier property, the water vapor permeability is preferably 50 g / m ² · 24 hrs · 40 ° C. · 90% RH or less, more preferably 10 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. More preferably, it is 1 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. This water vapor permeability is measured by the method described in JISK7129 (Method A). Thus, since the soft bag 2 has a water vapor barrier property, transpiration of water from the inside of the medical container 1 can be prevented. As a result, it is possible to prevent reduction and concentration of the medicine (specifically, chemical solution) to be filled. Moreover, the invasion of water vapor from the outside of the medical container 1 can be prevented.

Examples of the material for forming such a flexible bag 2 include various types such as polyethylene (PE), polypropylene (PP), polybutadiene, polyolefins such as ethylene-vinyl acetate copolymer (EVA), olefin elastomers, and styrene elastomers. Thermoplastic elastomers or those arbitrarily combined (blend resin, polymer alloy, laminate, etc.) can be mentioned. And it is preferable that the resin material to be used has the heat resistance and water resistance which can endure high pressure steam sterilization (autoclave sterilization).
In the present invention, it is preferable that the material for forming the soft bag 2 includes polyolefin. As a material for forming the flexible bag 2, polyethylene or polypropylene, a styrene thermoplastic elastomer such as a styrene-butadiene copolymer or a styrene-ethylene-butylene-styrene block copolymer, or an ethylene-propylene copolymer is particularly preferable. And a soft resin obtained by blending and softening an olefinic thermoplastic elastomer such as an ethylene-butene copolymer or a propylene-α-olefin copolymer. This material is preferable in that it has high strength and flexibility, heat resistance (particularly heat resistance during sterilization) and water resistance, and is particularly excellent in workability and can reduce manufacturing costs.

The soft bag may have a single-layer structure (single-layer body) made of the materials described above, or a multilayer in which a plurality of layers (particularly layers of different materials) are stacked for various purposes. A laminated body may be sufficient. In the case of a multilayer laminate, a plurality of resin layers may be stacked, or a metal layer may be stacked on at least one resin layer. In the case where a plurality of resin layers are stacked, the advantages of the respective resins can be provided together. For example, the impact resistance of the soft bag 2 can be improved, or anti-blocking properties can be imparted. Moreover, in the case of a thing with a metal layer, the gas barrier property etc. of the soft bag 2 can be improved. For example, when a film such as an aluminum foil is laminated, the gas barrier property can be improved and the light shielding property can be imparted. In addition, when a layer made of an oxide such as titanium oxide, aluminum oxide, or silicon oxide is formed, the transparency of the flexible bag 2 can be maintained while improving the gas barrier property, and the internal visibility can be secured. Can do. In addition, when the soft bag 2 is a multilayer laminated body, it is preferable that the material which forms the inner surface part is the material mentioned above.
The thickness of the sheet material constituting the flexible bag 2 is appropriately determined according to the layer configuration and the characteristics of the material used (flexibility, strength, water vapor permeability, heat resistance, etc.), and is not particularly limited. However, usually, it is preferably about 100 to 500 μm, and more preferably about 200 to 360 μm.
Moreover, although the volume of the medical container 1 changes with kinds etc. of the chemical | medical agent accommodated in an inside, it is preferable normally that the volume of a chemical | medical agent chamber is about 50-5000 ml.
The medical container discharge port 3 is for discharging the medicine (chemical solution) filled in the soft bag 2.

The discharge port 3 is fixed to the medicine chamber of the soft bag 2. The discharge port 3 includes a medical container hollow body 30, and the medical container hollow body 30 has a cylindrical portion 31 whose tip is closed, and a breakable portion 36 provided at the distal end of the cylindrical portion 31. Each of the first stress applying portion 34 and the other sheet 2b of the flexible bag 2 which are respectively provided so as to sandwich the breakable portion 36 of the cylindrical portion 31 and can be fixed to the inner surface of one sheet 2a of the flexible bag 2. And a second stress applying portion 35 that can be fixed to the inner surface. The breakable portion 36 breaks due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and opens the tubular portion 31. Further, the first stress applying part 34 or the second stress applying part 35 includes a first engaging part 37, and a cylindrical part 31 (or a cylindrical member provided so as to enclose the cylindrical part). The breakable portion 36 is broken by the spread between the first stress applying portion 34 and the second stress applying portion 35, and after the opening of the tubular portion 31, the first engaging portion 37 is engaged, It has a second engaging portion 38 that holds the first stress applying portion 34 or the second stress applying portion 35.
Further, the discharge port 3 includes a discharge port 50 that has a seal member 52 that closes the other end of the cylindrical portion 31 and can be connected to a medical needle tube. Furthermore, in the medical container 1 of this embodiment, the tubular portion 31 of the medical container hollow body 30 provided in the medical container hollow body 30 in the discharge port 3 when the breakable portion 36 is not broken. A needle tube entry inhibiting member 4 that inhibits the medical needle tube from entering the inside is housed.

The discharge port 3 of this embodiment includes a medical container hollow body 30, a discharge port 50 that seals an opening of the medical container hollow body 30 and allows connection (puncture) of a medical needle, and a discharge A cylindrical member 55 for attaching the port 3 (medical container hollow body 30) to the soft bag 2, the needle tube penetration inhibiting member 4 housed in the medical container hollow body 30, and the medical container hollow body 30 with a chemical solution 90 filled in the inside.
The discharge port 50 includes a seal member 52 capable of connecting (puncturing) a medical needle tube, and a cap member 51 for fixing the seal member 52 to the opening of the medical container hollow body 30. Yes. And the cap member 51 is fixed to the fixing | fixed part (flange part 39) provided in the base end part of the hollow body 30 for medical containers by ultrasonic fusion, high frequency fusion, heat fusion, etc. It is preferable that the cylindrical part 31 of the hollow body 30 for medical containers is transparently formed so that an internal medicine can be visually observed. Moreover, although the cylindrical part 31 of the hollow body 30 for medical containers may be a normal pressure, it is good also as a pressure reduction or a vacuum state. As described above, when the medicine container is in a reduced pressure or vacuum state, the effect of preventing degradation / degradation and the like of the medicine is improved.
The medicine 90 to be stored may be any powder or solid such as a granule or liquid. Drugs are formulated and dissolved in infusions. For example, antibiotics, vitamins (general vitamins), various amino acids, antithrombotics such as heparin, insulin, antitumor agents, analgesics, cardiotonics, statics Note: Anesthetic agents, anti-Parkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, antiviral agents, immunostimulants, and the like.

The discharge port 3 is a non-communication port in a normal state.
As shown in FIGS. 3, 5 to 8, the medical container hollow body 30 includes a cylindrical portion 31 having a hollow portion, a breakable portion 36 provided in the cylindrical portion 31, and a first stress. The applying portion 34, the second stress applying portion 35, the first engaging portion 37, and the breakable portion 36 are broken and engaged with the first engaging portion 37 after the opening of the tubular portion 31. A second engaging portion 38 is provided.
The medical container hollow body 30 includes a first fixing portion 21 (see FIG. 16) in which the first stress applying portion 34 is fixed to the inner surface of one sheet forming the drug chamber 11 of the soft bag 2. The second stress applying part 35 has a second fixing part 22 (see FIG. 16) fixed to the inner surface of the other sheet forming the drug chamber 11. And in the hollow body 30 for medical containers of this Example, the attachment part for attaching the discharge port 50 in which the connection (puncture) of a medical needle tube is possible is formed in the base end part of the cylindrical part 31. FIG. . Further, the base end portion of the tubular portion 31 extends a predetermined length from the breakable portion 36 to the base end side.
The breakable portion 36 of the medical container hollow body 30 is broken by the expansion between the first fixing portion 21 and the second fixing portion 22 with the soft bag 2 when the drug chamber 11 is pressed. .

As shown in FIGS. 5 to 7, the cylindrical portion 31 is a cylindrical portion whose front end portion is closed and whose proximal end portion is open, and a flange portion 39 provided at the proximal end portion and a first cylinder. A tapered portion that is continuous with the first cylindrical portion and has a tapered diameter toward the distal end side, a small-diameter cylindrical portion 32 that is continuous with the tapered portion, and a closed portion (tip portion) that is continuous with the small-diameter cylindrical portion 32 It consists of. The shape of the tip is preferably a dome shape, a cone shape, or a truncated cone shape, and particularly preferably a dome shape or a truncated cone shape. In this embodiment, the blocking portion has a dome shape.
It is preferable that the volume of the cylindrical part 31 is 1-30 ml. The length of the cylindrical portion is preferably 20 to 100 mm. The proximal end side of the flange portion is for fixing the cap member 51 that forms the discharge port 50.
As a material for forming the hollow body 30 for medical containers, rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, cyclic polyolefin [specifically, COP (cyclic olefin polymer) such as ZEONEX (registered trademark, manufactured by Nippon Zeon Co., Ltd.) ), COC (cyclic olefin copolymer) such as APEL (registered trademark, manufactured by Mitsui Chemicals)], polypropylene homopolymer, polyolefin such as high-density polyethylene, polystyrene, poly- (4-methylpentene-1), polycarbonate ABS resin, acrylic resin, polymethyl methacrylate (PMMA), polyacetal, polyarylate, polyacrylonitrile, polyvinylidene fluoride, ionomer, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate (PET), Examples thereof include polyesters such as polybutylene terephthalate (PBT), butadiene-styrene copolymers, various resins such as aromatic or aliphatic polyamides, and combinations of these arbitrarily.

In this embodiment, the first stress applying portion 34 and the second stress applying portion 35 extend forward from the vicinity of the breakable portion of the cylindrical portion 31 as shown in FIGS. 2 to 8. At the same time, the tip is a free end. The first stress applying unit 34 and the second stress applying unit 35 have a function of converting the force into stress for breaking the breakable portion when a force for opening the both is applied. The first stress applying part 34 and the second stress applying part 35 are preferably formed so as to face each other. Moreover, it is preferable that the main-body part of the 1st stress provision part 34 and the 2nd stress provision part 35 is formed in the vertically long rectangular shape. With such a configuration, when the soft bag 2 is pressed and inflated, the first stress applying part 34 and the second stress applying part 35 reliably apply the breaking stress to the breakable part 36.
Specifically, in the medical container hollow body 30 in the medical container 1 of this embodiment, the first stress applying part 34 and the second stress applying part 35 are as shown in FIGS. Vertically long flat plate portions 34a and 35a and side wall portions formed on both sides of the flat plate portion are provided. Furthermore, the first stress applying part 34 and the second stress applying part 35 are provided so as to extend in the axial direction of the cylindrical part 31. And the 1st stress application part 34 and the 2nd stress application part 35 become what a side wall part opposes. The first stress applying part 34 and the second stress applying part 35 are provided so as to face each other and be slightly separated from each other. Moreover, it is preferable that the front-end | tip (other end) of the 1st stress provision part 34 and the 2nd stress provision part 35 is a free end.

The breakable portion 36 may be configured such that when the stress is applied by the first stress applying portion 34 and the second stress applying portion 35, the tip portion of the tubular portion 31 can be vertically cut. preferable. The breakable portion 36 is formed so as to surround the proximal end portion of the first stress applying portion 34 or the second stress applying portion 35. Specifically, in this embodiment, as shown in FIGS. 5 and 7, the breakable portion 36 is the tip portion (specifically, the small diameter cylindrical portion 32) of the cylindrical portion 31, and The base end portion of the stress applying portion 34 and the cylindrical portion are formed in an annular shape.
And in the hollow body 30 for medical containers, as shown in FIG.2, FIG.3, FIG.5, FIG. 7 thru | or FIG. 9, the 1st stress provision part 34 or the 2nd stress provision part 35 is 1st. An engaging portion 37 is provided. The breakable portion 36 is broken in the tubular portion 31 due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and the first engaging portion is opened after the opening of the tubular portion 31. A second engaging portion 38 is provided that engages with 37 and holds the first stress applying portion 34 or the second stress applying portion 35.

In the medical container hollow body 30 of this embodiment, the breakable portion 36 is provided only on either the first stress applying portion 34 or the second stress applying portion 35 (in this embodiment, the first engagement member 36). The first engagement portion 37 and the second engagement portion 38 face each other via the breakable portion 36 (specifically, the first stress application portion 34 side having the joint portion 37 only). Are provided so as to face each other through the breakable portion 36 and in the axial direction of the cylindrical portion. The first engaging portion and the second engaging portion may be constituted by, for example, a protruding portion having one of the protrusions and the other engaging the protrusion with a claw portion at the tip. In the medical container hollow body 30 of this embodiment, as shown in FIG. 9, the first engaging portion 37 provided in the first stress applying portion 34 is provided in a portion close to the breakable portion 36. The front end surface of this protrusion is an inclined surface that is inclined toward the front end direction, and an edge projecting in the front end direction is provided at the end portion. The second engaging portion 38 provided in the cylindrical portion 31 (small diameter cylindrical portion 32) extends from the vicinity of the breakable portion 36, passes over the breakable portion 36, and further, the first stress applying portion 34. It is comprised by the protrusion part extended in the front-end | tip direction. The second engaging portion 38 has a claw capable of engaging with a protrusion (specifically, an edge protruding in the distal direction of the first engaging portion 37) as a first engaging portion at the tip. Part 60. The nail | claw part 60 is equipped with the edge which protrudes toward the 1st stress provision part 34 direction.
And in the hollow body 30 for medical containers of this Example, the 1st stress provision part 34 and the 2nd stress provision part 35 are provided with the flat parts 34a and 35a for adhering to the inner surface of the soft bag 2, The first engaging portion 37 and the second engaging portion 38 are formed so as to be located on an extension line in the axial direction of the medical container hollow body 30 of the flat portion 34. For this reason, the first engaging portion is secured by fixing the flat portions 34a and 35a of the first stress applying portion 34 and the second stress applying portion 35 to the inner surface of the soft bag 2 in the medical container hollow body 30. 37 also faces the inner surface in the vicinity of the fixing portion of the soft bag 2, and breaks the breakable portion 36 when the drug chamber 11 of the medical container 1 is pressed, the inclination of the first stress applying portion 34, and the first engagement. The movement of the joint portion 37 in the direction of the second engagement portion 38 is ensured.

And in the hollow body 30 for medical containers of this Example, as shown in FIG.5 and FIG.7, the breakable part 36 is between the 1st stress provision part 34 and the 2nd stress provision part 35. As shown in FIG. It has a tip side portion provided so as to pass through, and a first stress applying portion side portion extending in the side surface direction of the cylindrical portion 31 from the tip side portion. As shown in FIGS. 15 and 16, when the drug chamber 11 is pressed, the vicinity of the fixing portion of the first stress applying portion 34 to the soft bag 2 swells, and the first stress applying portion 34 is pulled. When the opening force is applied to the first stress applying part 34 in the direction away from the second stress applying part 35, the breakable part 36 breaks, and subsequently, the first stress applying part 34 As a result of the inclination, the first engagement portion 37 approaches the second engagement portion 38, and eventually the claw portion 60 of the second engagement portion 38 gets over the edge of the first engagement portion 37. As a result, both engage. Then, when the first engaging portion 37 and the second engaging portion 38 are engaged, the cylindrical portion 31 holds the first stress applying portion 34, and thereby the first engaging portion 34. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 31 is maintained.
The breakable part 36 is a breakable weak part. Specifically, the breakable part is preferably a thin part. The breakable portion 36 is preferably produced by forming a groove on the outer surface of the cylindrical portion 31. In this embodiment, the breakable portion 36 is produced by forming a groove portion having a V-shaped cross section. The angle of the groove is preferably 30 to 120 °, particularly 40 to 60 °, and the minimum thickness is preferably 0.05 to 0.3 mm, particularly 0.08 to 0.2 mm. By producing the groove forming portion at such an angle, when the soft bag 2 is inflated, the stress concentrates at the center of the breakable portion, and the groove is reliably broken. Further, the groove portion may have any shape as long as it is easily broken, and is not limited to the V shape as in the embodiment, and may be a semicircular shape, a semielliptical shape, or the like. Moreover, although the breakable part of the present invention can be broken by forming a thin part by forming a groove part, it is not limited to this. The breakable portion may be produced by, for example, forming a portion forming the breakable portion of the medicine storage portion with a material more fragile than the other portions. Specifically, it is preferable that a part forming the breakable part is made of an easily breakable material by multicolor molding, and the other part is made of a material that is not easily broken.
Further, the breakable portion 36 is any material as long as it can break the cylindrical portion 31 (drug storage portion) by the stress applied by the first stress applying portion 34 and the second stress applying portion 35. May be.

  Further, as shown in FIGS. 7 and 8, the first stress applying portion 34 and the second stress applying portion 35 include ribs 34b and 35b that are provided on respective surfaces facing each other and do not contact each other. It is preferable. Moreover, it is preferable that the flat part joined to the inner surface of the soft bag 2 is formed in the outer surface of flat plate part 34a, 35a. The flat portion forms a joint surface with the inner surface of the soft bag. In this embodiment, the flat surface portion is formed from the vicinity of the proximal end portion to the distal end of the first stress applying portion 34 and the second stress applying portion 35. The flat portion joined to the inner surface of the soft bag 2 is at least partially formed of a material that can be fixed to the inner surface of the soft bag 2. Specifically, the flat part joined to the inner surface of the soft bag 2 is partially or entirely compatible with the forming material of the soft bag 2 (particularly, the forming material forming the inner surface side of the soft bag 2). It is preferably formed of a certain resin. With such a configuration, the first stress applying part 34 and the second stress applying part 35 can be reliably bonded to the inner surface of the flexible bag 2. The resin compatible with the soft bag 2 is preferably the resin described above. The compatible resin is preferably a material that is the same as or similar to the constituent material of the soft bag. In an embodiment of the present invention, it is preferable that all of the first stress applying part or the second stress applying part are made of a resin compatible with the soft bag of the medical container, and the first stress applying part Alternatively, it is more preferable that all of the second stress applying part and the cylindrical part 31 are made of a resin compatible with the soft bag of the medical container. Moreover, the compatible resin layer may be produced by two-color molding. The compatible resin layer is preferably made flat so as to be easily joined to the inner surface of the soft bag.

Further, the first stress applying part 34 and the second stress applying part 35 are formed slightly apart between the first stress applying part 34 and the second stress applying part 35. As described above, the first stress applying part 34 and the second stress applying part 35 are not so separated from each other. For this reason, even if it presses between the 1st stress application part 34 and the 2nd stress application part 35 at the time of fixation to the soft bag 2, it is accept | permitted to the 1st stress application part 34 and the 2nd stress application part 35. The amount of deformation is small and there is no possibility that the breakable portion 36 will break. In the embodiment of the present invention, as shown in FIGS. 6 and 7, the side walls excluding the vicinity of the rear end portions of the flat plate portions 34a and 35a of the first stress applying portion 34 and the second stress applying portion 35 are raised. Thus, the first stress applying part 34 and the second stress applying part 35 are slightly separated from each other by forming protrusions at positions corresponding to the inner surfaces of the side walls.
In the medical container 1, the whole or a part of the flat portion 34 a of the first stress applying portion 34 is joined to the inner surface of the sheet of the flexible bag 2, whereby the first fixing portion 21 (see FIG. 16). Similarly, the whole or part of the flat surface portion of the second stress applying portion 35 is joined to the inner surface of the sheet of the flexible bag 2, whereby the second fixing portion 22 (see FIG. 16) is formed. It is formed. For this reason, the first stress applying part and the second stress applying part follow the spread between the first stress applying part and the fixed part of the second stress applying part of the soft bag when the drug chamber is pressed. It spreads, and the breakable part is opened on one sheet side to break.
The joining of the flat part of the first stress applying part 34 and the flat part of the second stress applying part 35 to the inner surface of each sheet of the flexible bag 2 is performed by ultrasonic fusion, high frequency fusion, thermal fusion or the like. Are preferred. Specifically, after the discharge port 3 is arranged at a position as shown in FIG. 1, the sheet is sandwiched from both sides of one sheet and the other sheet surface of the flexible bag 2 by a sealing mold and heat sealed. It is preferable.

The first stress applying part and the second stress applying part in the discharge port 3 are not limited to those having the above-described configuration, and can be joined to one sheet inner surface and the other sheet inner surface constituting the soft bag. In addition, any configuration may be used as long as it has a configuration capable of applying stress to the breakable portion in conjunction with the swelling of the soft bag. For example, it may not be formed to extend in the axial direction of the medicine container, but may be formed obliquely with respect to the medicine container.
Furthermore, in the discharge port 3 of this embodiment, the needle tube entry inhibiting member 4 is accommodated in the discharge port 3 of the medical container hollow body 30. As shown in FIG. 3, the needle tube intrusion inhibiting member 4 in this embodiment includes a main body portion 41 having a tip portion that can come into contact with the inside of the tip portion of the cylindrical portion 31 of the medical container hollow body 30, and a medical needle tube. A proximal end portion 43 with which the distal end can be brought into contact, and a connecting portion 42 for connecting the distal end portion 41 and the proximal end portion 42.
When the sealable member 52 is punctured with the medical needle tube when the breakable portion 36 of the medical container hollow body 30 is not broken (the state shown in FIG. 3), the tip of the needle is the needle tube intrusion inhibiting member 4. Abuts against the base end portion 43 to prevent entry. The operator recognizes that the breakable portion 36 of the medical container hollow body 30 is unbroken because the medical needle tube is not puncturable.
The length of puncture to the discharge port of the medical needle tube when the breakable portion 36 of the medical container hollow body 30 is not broken (state shown in FIG. 3) is such that the opening of the medical needle tube is inside the discharge port. It is preferable that the length does not allow communication.

In the needle tube entry inhibiting member 4 of this example, the main body portion 41 has a cross-shaped cross section having plate-like portions 41a, 41b, 41c, 41d extending in four axial directions as shown in FIGS. ing. The connecting portion 42 that connects the main body portion 41 and the base end portion 43 is formed by four ribs 42a, 42b, 42c, and 42d that extend in the outer edge direction from the center of the upper surface of the disk-like base end portion and protrude from the outer edge. The upper portions of the ribs 42a, 42b, 42c, and 42d are connected to the lower portions of the corresponding plate-like portions 41a, 41b, 41c, and 41d.
The needle tube entry inhibiting member 4 can flow out of the discharge port after the breakable portion 36 of the medical container hollow body 30 is broken. However, it is not limited to such a thing. The needle tube entry inhibiting member 4 may be any needle tube entry inhibiting member as long as it restricts puncture of the discharge port of the medical needle tube in the unbreakable state of the breakable portion 36 of the medical container hollow body 30. It is not limited to members.

In the medical container 1 of this embodiment, when the chemical chamber 11 is inflated by pressing the chemical chamber 11 of the medical container 1, this expansion (opening of the first fixing portion 21 and the second fixing portion 22) is performed. In conjunction with FIG. 16, as shown in FIG. 16, the first stress applying part 34 and the second stress applying part 35 of the medical container hollow body 30 open in the direction of the one sheet 2a and the other sheet 2b, First, the tip side portion of the breakable portion 36 is broken, and then the first stress applying portion side portion is broken. Then, the first stress applying portion side portion is deformed (curved), the cylindrical portion 31 is opened, communicates with the chemical chamber 11, and the needle tube intrusion inhibiting member 4 flows out of the port body as shown in FIG. The needle tube can be connected, and the drug in the discharge port is mixed with the drug in the drug solution chamber 11 of the soft bag 2. Further, due to the deformation (curvature) of the first stress applying portion side portion, the first engaging portion 37 and the second engaging portion 38 are engaged, and the cylindrical portion 31 is connected to the first stress applying portion 34. Hold. Thereby, the cylindrical part of the hollow body 30 for medical containers prevents obstruction | occlusion by the 1st stress provision part.
In addition, the discharge port 3 of this embodiment includes a cylindrical member 55 for attaching the discharge port 3 (medical container hollow body 30) to the soft bag 2, as shown in FIGS. The cylindrical member 55 is a cylindrical body that encloses an intermediate portion of the cylindrical part 31 of the medical container hollow body 30, and as shown in FIG. 14, the cylindrical part 31 of the medical container hollow body 30. This is a cylindrical body having a main body portion 56 fitted to the base portion and a diameter-expanding portion 57 that accommodates the flange portion 39 of the cylindrical portion 31. The cylindrical member 55 may be formed integrally with the cylindrical portion 31. Further, as the discharge port, the cylindrical member 55 may not be provided.

Moreover, as a discharge port and a hollow body for medical containers, what is shown to FIG. 17 thru | or FIG. 21 may be used. The basic configurations of the discharge port 3a and the medical container hollow body 30a of this embodiment are the same as those of the discharge port 3 and the medical container hollow body 30 described above. The difference between the two is the first engaging portion. And only the configuration of the second engaging portion.
In the medical container hollow body 30a of this embodiment, as shown in FIGS. 17 to 21, the first stress applying portion 34 includes a first engaging portion 37a. The breakable portion 36 is broken in the tubular portion 31 due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and the first engaging portion is opened after the opening of the tubular portion 31. A second engaging portion 38 a that engages with 37 a and holds the first stress applying portion 34 is provided.
In the medical container hollow body 30a of this embodiment, the breakable portion 36 is provided only on the first stress applying portion 34 side having the first engaging portion 37a, and the first engaging portion 37a. And the 2nd engaging part 38a is provided so that it may oppose via the breakable part 36 (specifically, it faces the axial direction of a cylindrical part via the breakable part 36). One of the first engaging portion and the second engaging portion is a protrusion, and the other is constituted by a protruding portion having a claw portion at the tip end portion that engages with the protrusion. In the medical container hollow body 30a of this embodiment, as shown in FIG. 20, the second engagement portion 38a provided in the cylindrical portion 31 (small-diameter cylindrical portion 32) is close to the breakable portion 36. It is comprised by the protrusion provided in the site | part, The front end surface of this protrusion is an inclined surface which inclines toward the base end direction of the cylindrical part 31, The edge which protrudes in the base end direction at the edge part It has. The first engagement portion 37 a provided in the first stress applying portion 34 extends from the vicinity of the breakable portion 36 of the small diameter cylindrical portion 32, passes over the breakable portion 36, and is the base end of the tubular portion 31. It is comprised by the protrusion part extended in a direction. The first engaging portion 37a has a claw portion engageable with a protrusion (specifically, a distal end portion of the protrusion of the second engaging portion 38a) which is the second engaging portion 38a at the tip thereof. 60. The nail | claw part 60 is provided with the edge which protrudes toward a cylindrical part direction.
And also in the hollow body 30a for medical containers of this embodiment, the breakable part 36 is provided so as to pass between the first stress applying part 34 and the second stress applying part 35. And a first stress applying part side portion extending in the side surface direction of the cylindrical part 31 from the tip side part. Then, as shown in FIG. 21, the first stress applying portion 34 is given a force that opens in a direction away from the second stress applying portion 35, whereby the breakable portion 36 is broken, and subsequently When the first stress applying portion 34 is inclined, the first engaging portion 37a comes close to the second engaging portion 38a, and the claw portion 60 of the first engaging portion 37a eventually becomes the second engaging portion 37a. By getting over the edge of the engaging portion 38a, both engage. And the cylindrical part 31 hold | maintains the 1st stress provision part 34 by the 1st engaging part 37a and the 2nd engaging part 38a engaging, Thereby, the 1st engaging part 34 is obtained. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 31 is maintained.

Further, the discharge port and the hollow body for a medical container may be as shown in FIGS. The basic configurations of the discharge port 3b and the medical container hollow body 30b in this embodiment are the same as those of the discharge port 3 and the medical container hollow body 30 described above, and the difference between the two is the first engaging portion. And only the configuration of the second engaging portion.
In the medical container hollow body 30b of this embodiment, as shown in FIGS. 22 to 27, the first stress applying part 34 includes a first engaging part 37b. The breakable portion 36 is broken in the tubular portion 31 due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and the first engaging portion is opened after the opening of the tubular portion 31. A second engaging portion 38b that engages with 37b and holds the first stress applying portion 34 is provided.
In the medical container hollow body 30b of this embodiment, the breakable portion 36 is provided only on the first stress applying portion 34 side having the first engaging portion 37b, and the first engaging portion 37b. And the 2nd engaging part 38b is provided so that it may oppose via the breakable part 36 (specifically, it faces the axial direction of a cylindrical part via the breakable part 36). One of the first engaging portion and the second engaging portion is a protrusion having a through hole, and the other is a protruding portion having a tip portion that enters and engages in the through hole. In the medical container hollow body 30b of this embodiment, as shown in FIG. 25, the first engaging portion 37b provided in the first stress applying portion 34 is provided in a portion close to the breakable portion 36. And has a through hole 62. Moreover, the front end surface of this protrusion is an inclined surface which inclines toward the front end direction. Further, the second engaging portion 38b provided in the cylindrical portion 31 (small diameter cylindrical portion 32) extends from the vicinity of the breakable portion 36, passes over the breakable portion 36, and further, the first stress applying portion 34. It is comprised by the protrusion part extended in the front-end | tip direction. The second engaging portion 38b can enter the through hole 62 of the projection which is the first engaging portion at the tip thereof, and enters the through hole 62, penetrates, and then passes through the through hole. A claw portion 61 that can be engaged with 62 edges is provided. The nail | claw part 61 is equipped with the edge which protrudes toward the 1st stress provision part 34 direction.

And in the hollow body 30b for medical containers of this Example, the 1st stress provision part 34 and the 2nd stress provision part 35 are provided with the flat part for adhering to the inner surface of the soft bag 2, 1st The engaging portion 37b and the second engaging portion 38b are formed so as to be located on an extension line in the axial direction of the hollow medical container hollow body 30b. For this reason, the first engaging portion 37b and the first hollow portion 30b are fixed to the inner surface of the soft bag 2 by fixing the flat portions of the first stress applying portion 34 and the second stress applying portion 35 to the hollow body 30b. The second engaging portion 38b also faces the inner surface in the vicinity of the fixing portion of the soft bag 2, and when the drug chamber 11 of the medical container is pressed, the breakable portion 36 is broken, the first stress applying portion 34 is inclined, The movement of the first engagement portion 37b in the direction of the second engagement portion 38b is ensured.
And in the hollow body 30b for medical containers of this Example, as shown in FIG.26 and FIG.27, the breakable part 36 is between the 1st stress provision part 34 and the 2nd stress provision part 35. As shown in FIG. It has a tip side portion provided so as to pass through, and a first stress applying portion side portion extending in the side surface direction of the cylindrical portion 31 from the tip side portion. When the opening force is applied to the first stress applying part 34 in a direction away from the second stress applying part 35, the breakable part 36 is broken, and subsequently, the first stress applying part 34 is By tilting, the first engaging portion 37b comes close to the second engaging portion 38b, and eventually the tip of the second engaging portion 38b enters the through hole 62 of the first engaging portion 37b. Then, the two engage with each other. And the cylindrical part 31 hold | maintains the 1st stress provision part 34 by the 1st engaging part 37b and the 2nd engaging part 38b engaging, Thereby, the 1st engaging part 34 is obtained. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 31 is maintained.

The discharge port and the medical container hollow body may be as shown in FIGS. The basic configurations of the discharge port 3c and the medical container hollow body 30c of this embodiment are the same as those of the discharge port 3 and the medical container hollow body 30 described above. The main difference between the two is the first relationship. It is the structure of a joint part and a 2nd engaging part. In this embodiment, the medical container hollow body 30c includes a cylindrical member 55a that encloses the cylindrical portion, and the first engaging portion 37c is formed in the first stress applying portion 34. The second engaging portion 38c is provided at the tip of the cylindrical member 55a and is formed by a concave portion that engages with the protrusion.
The discharge port 3c of this embodiment includes a medical container hollow body 30c, a discharge port 50 that seals an opening of the medical container hollow body 30c and allows connection (puncture) of a medical needle, and a discharge A cylindrical member 55a for attaching the port 3c (medical container hollow body 30c) to the soft bag 2, the needle tube penetration inhibiting member 4 housed in the medical container hollow body 30, and the medical container hollow body And a chemical solution 90 filled in 30c. The tubular member 55a is a tubular body that encloses an intermediate portion of the tubular portion 31 of the medical container hollow body 30c. As shown in FIGS. 30 and 31, the tubular body of the medical container hollow body 30c. A main body portion 56 to which the shape portion 31 is fitted, and a diameter-expanded portion 57 for accommodating the flange portion 39 of the tubular portion 31.
In addition, the discharge port 3c and the medical container hollow body 30c of this embodiment are configured such that the first stress applying portion 34 is the first engaging portion as shown in FIGS. 28, 29, 32, and 33. 37c. Then, the breakable portion 36 is broken at the distal end portion of the cylindrical member 55 a due to the spread between the first stress applying portion 34 and the second stress applying portion 35, and after the opening of the cylindrical portion 31, A recess is provided that constitutes a second engagement portion 38c that engages with the engagement portion 37c and holds the first stress applying portion 34.

In the medical container hollow body 30c of this embodiment, the breakable part 36 is provided only on the first stress applying part 34 side having the first engaging part 37c, and the first engaging part 37c is provided. And the 2nd engaging part 38c is provided so that it may oppose via the breakable part 36 (specifically, it faces the axial direction of a cylindrical part via the breakable part 36). One of the first engaging portion and the second engaging portion is a protrusion, and the other is a recess that houses and holds the protrusion.
In the medical container hollow body 30c of this embodiment, as shown in FIG. 35, the first engaging portion 37c provided in the first stress applying portion 34 is provided in a portion close to the breakable portion 36. And a rib 63 protruding in the side surface direction at the tip. Moreover, the front end surface of this protrusion is an inclined surface which inclines toward the front end direction.
As shown in FIG. 29, the tubular member 55 a encloses the tubular portion 31 of the medical container hollow body 30 c and has a distal end portion that reaches the breakable portion 36. Then, a second engaging portion 38c formed by a concave portion that holds the first engaging portion (protrusion) 37c provided in the first stress applying portion 34 and holds the stored protrusion at the tip portion. It has. Therefore, in this embodiment, the second engaging portion 38c is formed by the tip portion and the concave portion of the cylindrical member 55a. Then, the first engaging portion 37c can enter the recess that forms the second engaging portion 38c, and after entering, the rib 63 engages with the edge of the recess.

And also in the hollow body 30c for medical containers of this Example, the 1st stress provision part 34 and the 2nd stress provision part 35 are provided with the flat parts 34a and 35a for adhering to the inner surface of the soft bag 2, The first engaging portion 37c and the second engaging portion 38c are formed so as to be positioned on an extension line in the axial direction of the medical container hollow body 30c of the flat portion 34a. Therefore, the first engaging portion is secured by fixing the flat portions 34a and 35a of the first stress applying portion 34 and the second stress applying portion 35 to the inner surface of the soft bag 2 with the medical container hollow body 30c. 37 also faces the inner surface in the vicinity of the fixing portion of the soft bag 2, and breaks the breakable portion 36 when the drug chamber 11 of the medical container 1 is pressed, the inclination of the first stress applying portion 34, and the first engagement. The movement of the joint portion 37c in the direction of the second engagement portion 38c is ensured.
And also in the hollow body 30c for medical containers of this Example, as shown in FIG.32 and FIG.33, the breakable part 36 is between the 1st stress provision part 34 and the 2nd stress provision part 35. As shown in FIG. It has a tip side portion provided so as to pass through, and a first stress applying portion side portion extending in the side surface direction of the cylindrical portion 31 from the tip side portion. When the opening force is applied to the first stress applying part 34 in a direction away from the second stress applying part 35, the breakable part 36 is broken, and subsequently, the first stress applying part 34 is By tilting, the first engagement portion 37c approaches the second engagement portion 38c, and the end portion of the first engagement portion 37c eventually enters the recess of the second engagement portion 38c. , Both engage. And the cylindrical part 31 hold | maintains the 1st stress provision part 34 by the 1st engaging part 37c and the 2nd engaging part 38c engaging, Thereby, the 1st engaging part 34 is obtained. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 31 is maintained.

The medical container of the present invention may be as shown in FIG.
The difference between the medical container 20 of this embodiment and the medical container 1 described above is that the soft bag 2 has a different form and has a mixed injection port.
The medical container 20 includes a soft bag 2, a discharge port 3 and a mixed injection port 8 attached to the soft bag 2. As the discharge port 3, those described above are preferably used.
As shown in FIG. 36, the medical container 20 includes a soft bag 2, a chemical solution, a discharge port 3, and a mixed injection port 8.
As shown in FIG. 36, the soft bag 2 is divided into a first drug chamber (chemical solution chamber) 11 and a second drug chamber (chemical solution chamber) 12 by a partitionable weak seal portion 9 for separation.
In addition, as shown in FIG. 36, the soft bag 2 is provided between the discharge port 3 in the vicinity of the distal end portion on the drug chamber side and fixed between the first stress applying portion and the second stress applying portion. A peelable spread suppressing sheet fixing portion 25 for suppressing spread is provided. In addition, the peelable spread suppressing inter-sheet fixing portion for suppressing the spread between sheets fixed to the medical container 1 of the above-described embodiment by the first stress applying portion and the second stress applying portion. May be provided.
In the embodiment shown in FIG. 36, the inter-sheet fixing portion 25 for suppressing spread is formed so as to surround the vicinity of the distal end portions of the first stress applying portion and the second stress applying portion of the discharge port 3. It is preferable that the inter-sheet fixing portion for suppressing the spread is not peeled off by pressure applied to the soft bag 2 before use such as during transportation, but is peelable when the soft bag 2 is strongly pressed with a finger. The inter-sheet fixing portion 25 is preferably in an arc shape that is continuous with the position near the tip of the stress applying portion and inside the drug chamber as in the illustrated embodiment. Note that the inter-sheet fixing portion 25 may be a plurality of dot-like ones instead of being continuous. Furthermore, the inter-sheet fixing part 25 may be provided in such a manner that one or two stress applying parts 34 and 35 are sandwiched between the vicinity of the tip of the stress applying part and on the side surface thereof. And as the spreading | diffusion suppression sheet fixing | fixed part 25, as shown in FIG. 36, both ends do not reach the seal | sticker part 6, and do not form the chamber partitioned off with the chemical | medical agent chamber 11. As shown in FIG.

The inter-sheet fixing part 25 is preferably formed by fusing the soft bag 2 so as to be peelable. The fusion is preferably thermal fusion, high frequency fusion or the like. The inter-sheet fixing part 25 is preferably performed by a hot press, and the mold temperature can be formed by performing the process at a temperature lower by 10 ° C. or more than the melting temperature of the forming material of the soft bag 2. By including the inter-sheet fixing portion for suppressing the spread, there is no possibility that the soft bag 2 swells during transportation and the first stress applying portion and the second stress applying portion are cleaved. In addition, as a shape of the fixing part between sheet | seats for expansion suppression, what kind of thing may be sufficient as long as it can prevent that a cylindrical part is fractured | ruptured before use, such as during transportation.
As shown in FIG. 36, the soft bag 2 is partitioned into a first drug chamber 11 and a second drug chamber 12 by a partition weak seal portion 9 that can be peeled off. As shown in FIG. 36, the partition weak seal portion 9 is provided so as to cross the entire lateral direction of the drug chamber of the soft bag 2. The partition weak seal portion 9 is formed by fusing the sheet material of the soft bag 2 in a band shape. In the embodiment of the present invention, strong seal portions 9 a that do not substantially peel off are formed at both ends of the partition weak seal portion 9. The partition weak seal portion 9 of the embodiment peels off when the second drug chamber 12 is strongly pressed with a finger or the like (when squeezed or gripped), and is separated from the first drug chamber 11 and the second drug chamber. 12 can be communicated.
The peeling strength of the partition weak seal portion 9 is preferably such that it does not peel off by the pressure applied to the soft bag 2 during transportation but peels when the soft bag 2 is strongly pressed with a finger or the like. The partition weak seal portion 9 is preferably formed by fusing the soft bag 2. The fusion is preferably thermal fusion, high frequency fusion or the like.
Since the soft bag 2 has the two drug chambers 11 and 12 partitioned by the partition weak seal portion 9 in this way, drugs of different components can be mixed aseptically in the soft bag 2. it can. In addition, in the embodiment shown in FIG. 36, the partition weak seal portion 9 is formed in a strip shape horizontally with respect to the soft bag 2, but is not limited to this.

In the drug chambers 11 and 12 of the soft bag 2, infusion agents (chemical solutions) are respectively stored. As such an infusion, for example, two or more liquids such as peritoneal dialysis solution, transcentral vein infusion, transperipheral vein infusion, transperipheral vein injection, liquid nutrient, etc. Those that need to be mixed are preferred. Examples of the infusion include physiological saline, electrolyte solution, Ringer's solution, high calorie infusion, glucose solution, water for injection, amino acid electrolyte solution, and the like, but are not limited thereto. For example, a glucose electrolyte solution is stored in one of the drug rooms, an amino acid solution is stored in the other, and water-soluble vitamins such as vitamin B1, vitamin B2, vitamin B6, vitamin C, panthenol, and nicotinamide are stabilized in both chambers. Can be appropriately sorted and stored. In this case, a vitamin-containing high-calorie total infusion solution can be obtained by storing a liquid preparation mainly composed of fat-soluble vitamins such as vitamin A, vitamin D, vitamin E, and vitamin K in a drug container attached to a drug room described later. .
A mixed injection port 8 is attached to the upper end side seal portion 5. A well-known port can be used as the mixed injection port.

Although the medical container 20 of the embodiment described above includes the inter-sheet fixing portion 25 for suppressing expansion as described above, the present invention is not limited to this, and the medical container 20a of the embodiment shown in FIG. As described above, it may be one that does not have the inter-sheet fixing portion 25 for suppressing expansion.
48, the soft bag 2 may include a weak seal portion 26 for inhibiting communication that is formed so as to surround the upper portion of the discharge port 3. As shown in FIG. A small chamber 27 isolated from the first drug chamber 11 is formed by the weak seal portion 26 for inhibiting communication. This small room 27 is an empty room in the embodiment of the present invention. However, the small chamber 27 may contain a predetermined liquid (for example, physiological saline) or a trace element injection solution. The small chamber 27 may be in a dry state, but may be filled with a small amount of liquid for wet heat sterilization. Further, a passage through which some water vapor or medicine passes through the communication inhibiting weak seal portion 26 may be formed so as to communicate with the small chamber 27 at the above-described level. The weak seal portion 26 for inhibiting communication can be formed by heat-sealing the sheet material in a band shape (thermal fusion, high frequency fusion, ultrasonic fusion, etc.). In the embodiment shown in FIG. 48, the communication inhibiting weak seal portion 26 is formed in an inverted U-shape. Further, the weak seal portion 26 for inhibiting communication has a trapezoidal shape with the short side on the upper side, a triangular shape with the discharge port at the top, a triangular shape with the discharge port at the bottom, a polygonal shape such as a quadrangle, a substantially semicircular shape, A substantially semi-elliptical shape may be used.

In the medical container discharge port and the medical container hollow body of all the embodiments described above, as shown in FIGS. 49 to 51, the breakable portion 36 includes the first engaging portion and the second engaging portion. You may provide the part fracture | ruptureable part defect | deletion part provided between the engaging parts. 49 is a front view of another embodiment of the medical container discharge port of the present invention, and FIG. 50 is a right side view of another embodiment of the medical container hollow body of the present invention. 51 is a perspective view of the medical container hollow body shown in FIG. 50.
The breakable portion 36 of the medical container discharge port 3d (medical container hollow body 30d) of this embodiment surrounds the proximal end portion of the first stress applying portion 34 or the second stress applying portion 35. A partially breakable portion missing portion 65 that is formed and located between the first engaging portion 37 and the second engaging portion 38 is provided. And the defect | deletion part 65 forms the plastically deformable part. Then, the first stress applying part or the second stress applying part is not separated from the hollow body 30d by the defect part 65.
Specifically, in this embodiment, the breakable portion 36 is the distal end portion of the tubular portion 31 and the proximal end portion of the first stress applying portion 34 as shown in FIGS. 49 to 51. Although it has a start end and a terminal end so as to be separated from the cylindrical portion, it is formed in a substantially annular shape. A breakable portion missing portion 65 is formed between the start end and the end of the breakable portion 36. The breakable portion 36 is provided only in one of the first stress applying portion 34 and the second stress applying portion 35 (in this embodiment, only the first stress applying portion 34 side). Although the defect portion 65 is plastically deformed, it does not break in the widening operation (breaking operation of the breakable portion 36) between the first stress applying portion 34 and the second stress applying portion 35. Therefore, the first stress applying part 34 having the breakable part 36 has a hollow body 30d in a widening operation (breaking operation of the breakable part 36) between the first stress applying part 34 and the second stress applying part 35. It has become less segregated. The width of the defect portion 65, in other words, the distance between the start and end of the breakable portion 36 is preferably about 4 to 9 mm, and particularly preferably 6 to 8 mm. In the case where the partially breakable portion missing portion 65 is provided, the material for forming the hollow body, particularly the forming material for the partially breakable portion missing portion, has a tensile elongation (breaking elongation) of 20% or more. Preferably there is. The thickness of the plastically deformable portion is preferably 1.0 to 1.5 mm.

Next, an embodiment in which a medical container hollow body is applied to a drug container will be described.
As shown in FIGS. 37 to 38, the drug container 7 of this embodiment is filled in the hollow body 70 for medical use, a sealing member 72 for sealing the opening of the hollow body 70, and the hollow body 70. The medicine 73 is made.
The medical container hollow body 70 sandwiches the tubular portion 71 with the closed end portion, the breakable portion 76 provided at the distal end portion of the tubular portion 71, and the breakable portion 76 of the tubular portion 71. A first stress applying portion 74 that is provided and can be fixed to the inner surface of one sheet 2a of the soft bag 2 and a second stress applying portion 75 that can be fixed to the inner surface of the other sheet 2b of the soft bag 2 are provided. . The breakable portion 76 breaks due to the spread between the first stress applying portion 74 and the second stress applying portion 75 and opens the cylindrical portion 71.
Furthermore, the first stress applying part 74 or the second stress applying part 75 includes a first engaging part 77 and has a cylindrical part 71 (or a cylindrical member provided so as to enclose the cylindrical part). The breakable portion 76 breaks due to the spread between the first stress applying portion 74 and the second stress applying portion 75, and after the opening of the tubular portion 71, the first engaging portion 77 is engaged, The second engaging portion 78 that holds the first stress applying portion 74 or the second stress applying portion 75 is provided.
Then, when the first engaging portion 77 and the second engaging portion 78 are engaged, the cylindrical portion (or the cylindrical member) becomes the first stress applying portion 74 or the second stress applying portion 75. Thus, the opening state of the cylindrical portion 71 is maintained.
And the 1st stress provision part 74 and the 2nd stress provision part 75 are the same structures as the 1st stress provision part 34 and the 2nd stress provision part 35 which were demonstrated in the hollow body 30 for medical containers mentioned above. It is preferable that In addition, the breakable portion 76, the first engaging portion 77, and the second engaging portion 78 are also the breakable portion 36 and the first engaging portion 37 described in the medical container hollow body 30 described above. The second engaging portion 38 has the same configuration.

In the medicine container 7 and the medical container hollow body 70, as shown in FIGS. 37 to 39, the first stress applying portion 74 or the second stress applying portion 75 includes the first engaging portion 77. It has. In the tubular portion 71, the breakable portion 76 is broken by the spread between the first stress applying portion 74 and the second stress applying portion 75, and the first engaging portion is opened after the opening of the tubular portion 71. A second engaging portion 78 that engages with 77 and holds the first stress applying portion 74 or the second stress applying portion 75 is provided.
In the medical container hollow body 70 of this embodiment, the breakable portion 76 is provided only on one of the first stress applying portion 74 and the second stress applying portion 75 (in this embodiment, the first engagement member 76). The first engaging portion 77 and the second engaging portion 78 face each other via the breakable portion 76 (specifically, the first stress applying portion 74 side having the joining portion 77). Are provided so as to face each other through the breakable portion 76 and in the axial direction of the cylindrical portion.
And in the hollow body 70 for medical containers of this Example, as shown in FIG. 39, the 1st engaging part 77 provided in the 1st stress provision part 74 is the site | part close to the breakable part 76 The tip end surface of the projection is an inclined surface that inclines toward the tip direction of the hollow body, and has an edge protruding in the tip direction at the end. The second engaging portion 78 provided in the cylindrical portion 71 extends from the vicinity of the breakable portion 76, passes over the breakable portion 76, and further extends in the distal direction of the first stress applying portion 74. It is comprised by the protrusion part. The second engagement portion 78 has a claw that can be engaged with a protrusion (specifically, an edge protruding in the distal direction of the first engagement portion 77) that is the first engagement portion at the distal end. A portion 79 is provided. The nail | claw part 79 is equipped with the edge which protrudes toward the 1st stress provision part 74 direction.
And in the hollow body 70 for medical containers of this Example, the 1st stress provision part 74 and the 2nd stress provision part 75 are provided with the flat parts 74a and 75a for adhering to the inner surface of the soft bag 2, The first engaging portion 77 and the second engaging portion 78 are formed so as to be positioned on an extension line in the axial direction of the medical container hollow body 70 of the flat portion. For this reason, the first engaging portion 77 is secured by fixing the flat portions 74a and 75a of the first stress applying portion 74 and the second stress applying portion 75 to the inner surface of the soft bag. Is also directed to the inner surface in the vicinity of the fixing portion of the soft bag, the breakable portion 76 is broken when the drug chamber of the medical container is pressed, the first stress applying portion 74 is inclined, and the first engaging portion 77 is The movement in the direction of the second engagement portion 78 is ensured.

And also in the hollow body 70 for medical containers of this Example, as shown in FIG. 37, the breakable part 76 passes between the first stress applying part 74 and the second stress applying part 75. It has a provided tip side part and a first stress applying part side part extending in the side surface direction of the cylindrical part 71 from the tip side part. When the opening force is applied to the first stress applying part 74 in a direction away from the second stress applying part 75, the breakable part 76 is broken, and subsequently, the first stress applying part 74 is By tilting, the first engaging portion 77 comes close to the second engaging portion 78, and eventually the claw portion 79 of the second engaging portion 78 gets over the edge of the first engaging portion 77. Thus, both engage. Then, when the first engaging portion 77 and the second engaging portion 78 are engaged, the cylindrical portion 71 holds the first stress applying portion 74, thereby the first engaging portion 74. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 71 is maintained.
The drug 73 stored in the drug container 7 may be any powder, granular or other solid, liquid or the like. Drugs are formulated and dissolved in infusions. For example, antibiotics, vitamins (general vitamins), various amino acids, antithrombotics such as heparin, insulin, antitumor agents, analgesics, cardiotonics, statics Note: Anesthetic agents, anti-Parkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, antiviral agents, immunostimulants, and the like.
The volume of the cylindrical part 71 of the medicine container 7 is preferably 1 to 30 ml. The length of the cylindrical portion is preferably 20 to 100 mm.
Examples of the material for forming the medical container hollow body 70 and the sealing member 72 include polyolefin (for example, polyethylene, polypropylene, polybutadiene, ethylene-propylene copolymer, a mixture containing polyolefin such as a mixture of polypropylene and polyethylene or polybutene), and These partially cross-linked products, ethylene-vinyl acetate copolymer (EVA), polyester (polyethylene terephthalate, polybutylene terephthalate, etc.), soft vinyl chloride resin, polyvinyl acetate, polyvinylidene chloride, silicone, polyurethane, polyamide elastomer, polyester elastomer Etc. are preferred.

Moreover, as a chemical | medical agent container of this invention, what is shown to FIG. 40 and FIG. 41 may be sufficient. The basic configuration of the drug container 7a and the medical container hollow body 70a of this embodiment is the same as that of the drug container 7 and the medical container hollow body 70 described above, and the difference between the two is the first engaging portion. And only the configuration of the second engaging portion.
In addition, the first stress applying portion 74 and the second stress applying portion 75 of the medicine container 7a and the medical container hollow body 70a of this embodiment are the first described in the medical container hollow body 30 described above. It is preferable that the configuration is the same as that of the stress applying portion 34 and the second stress applying portion 35. The breakable portion 76 has the same configuration as the breakable portion 36 described in the medical container hollow body 30 described above. Further, the first engaging portion 77a and the second engaging portion 78a are shown in FIGS. 17 to 21 and described in the medical container hollow body 30a described above. It has the same configuration as the two engaging portions 38a.
In the drug container 7a and the medical container hollow body 70a of this embodiment, as shown in FIGS. 40 and 41, the first stress applying portion 74 includes a first engaging portion 77a. In the tubular portion 71, the breakable portion 76 is broken by the spread between the first stress applying portion 74 and the second stress applying portion 75, and the first engaging portion is opened after the opening of the tubular portion 71. A second engaging portion 78 a that engages with 77 a and holds the first stress applying portion 74 is provided.
In the medical container hollow body 70a of this embodiment, the breakable portion 76 is provided only on the first stress applying portion 74 side having the first engaging portion 77a, and the first engaging portion 77a. And the 2nd engaging part 78a is provided so that it may oppose via the breakable part 76 (specifically, it faces the axial direction of a cylindrical part via the breakable part 76). And as shown in FIG. 41, the 2nd engaging part 78a provided in the cylindrical part 71 (small diameter cylindrical part) is comprised by the protrusion provided in the site | part close to the breakable part 76, The distal end surface of the protrusion is an inclined surface that is inclined toward the proximal direction of the cylindrical portion 71, and has an edge protruding in the proximal direction at the end. The first engaging portion 77 a provided in the first stress applying portion 74 extends from the vicinity of the breakable portion 76 of the small diameter cylindrical portion, passes over the breakable portion 76, and is in the proximal direction of the tubular portion 71. It is comprised by the protrusion part extended in. The first engaging portion 77a is engageable with a projection (specifically, an edge protruding in the proximal direction of the second engaging portion 78a) as the second engaging portion 78a at the tip thereof. A claw portion 79 is provided. The nail | claw part 79 is provided with the edge which protrudes toward a cylindrical part direction.
Also in the medical container hollow body 70a of this embodiment, the breakable portion 76 is provided so as to pass between the first stress applying portion 74 and the second stress applying portion 75. And a first stress applying portion side portion extending in the side surface direction of the cylindrical portion 71 from the tip side portion. Then, by applying a force that opens the first stress applying part 74 in a direction away from the second stress applying part 75, the breakable part 76 breaks, and subsequently, the first stress applying part 74 When 74 inclines, the 1st engaging part 77a adjoins to the 2nd engaging part 78a, and the nail | claw part 79 of the 1st engaging part 77a eventually changes the edge of the 2nd engaging part 78a. By getting over, both engage. Then, the first engaging portion 77a and the second engaging portion 78a are engaged, so that the cylindrical portion 71 holds the first stress applying portion 74, whereby the first engaging portion 74 is retained. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 71 is maintained.
And also in the hollow body 70a for medical containers of this Example, the 1st stress provision part 74 and the 2nd stress provision part 75 are provided with the flat parts 74a and 75a for adhering to the inner surface of a soft bag, The first engaging portion 77a and the second engaging portion 78a are formed so as to be positioned on an extension line in the axial direction of the medical container hollow body 70 of the flat portion.

Moreover, as a chemical | medical agent container of this invention, what is shown to FIG. 42 and FIG. 43 may be sufficient. The basic configurations of the drug container 7b and the medical container hollow body 70b of this embodiment are the same as those of the drug container 7 and the medical container hollow body 70 described above. The difference between the two is the first engaging portion. And only the configuration of the second engaging portion.
In addition, the first stress applying portion 74 and the second stress applying portion 75 of the medicine container 7b and the medical container hollow body 70b of this embodiment are the first described in the medical container hollow body 30 described above. It is preferable that the configuration is the same as that of the stress applying portion 34 and the second stress applying portion 35. The breakable portion 76 has the same configuration as the breakable portion 36 described in the medical container hollow body 30 described above. Further, the first engaging portion 77b and the second engaging portion 78b are shown in FIGS. 22 to 27 and described in the above-described medical container hollow body 70b. It has the same configuration as the two engaging portions 38b.
In the medical container hollow body 70b of this embodiment, as shown in FIGS. 42 and 43, the first stress applying portion 74 includes a first engaging portion 77b. In the tubular portion 71, the breakable portion 76 is broken by the spread between the first stress applying portion 74 and the second stress applying portion 75, and the first engaging portion is opened after the opening of the tubular portion 71. A second engaging portion 78b that engages with 77b and holds the first stress applying portion 74 is provided.
In the medical container hollow body 70b of this embodiment, the breakable portion 76 is provided only on the first stress applying portion 74 side having the first engaging portion 77b, and the first engaging portion 77b. And the 2nd engaging part 78b is provided so that it may oppose via the breakable part 76 (specifically, it faces the axial direction of a cylindrical part via the breakable part 76). One of the first engaging portion and the second engaging portion is a protrusion having a through hole, and the other is a protruding portion having a tip portion that enters and engages in the through hole. In the medical container hollow body 70b of this embodiment, as shown in FIG. 43, the first engaging portion 77b provided in the first stress applying portion 74 is provided in a portion close to the breakable portion 76. And has a through-hole 83. Moreover, the front end surface of this protrusion is an inclined surface which inclines toward the front end direction. Further, the second engaging portion 78b provided in the cylindrical portion 71 (small-diameter cylindrical portion) extends from the vicinity of the breakable portion 76, passes over the breakable portion 76, and further of the first stress applying portion 74. It is comprised by the protrusion part extended in a front end direction. The second engaging portion 78b can enter into the through hole 83 of the protrusion which is the first engaging portion at the tip thereof, and enters the through hole 83, penetrates, and then passes through the through hole. A claw portion 79 that can be engaged with 83 edges is provided. The nail | claw part 79 is equipped with the edge which protrudes toward the 1st stress provision part 74 direction.

And in the hollow body 70b for medical containers of this Example, the 1st stress provision part 74 and the 2nd stress provision part 75 are provided with the flat parts 74a and 75a for adhering to the inner surface of a soft bag, The first engaging portion 77b and the second engaging portion 78b are formed so as to be positioned on an extension line in the axial direction of the flat medical container hollow body 70b. For this reason, the first engaging portion is secured by fixing the flat portions 74a and 75a of the first stress applying portion 74 and the second stress applying portion 75 to the inner surface of the soft bag 2 to the medical container hollow body 70b. 77 also faces the inner surface in the vicinity of the fixing portion of the soft bag, the breakable portion 76 is broken when the drug chamber of the medical container is pressed, the first stress applying portion 74 is inclined, and the first engaging portion 77b. The movement in the direction of the second engagement portion 78b is ensured.
In the medical container hollow body 70b according to this embodiment, the breakable portion 76 includes a distal end portion provided so as to pass between the first stress applying portion 74 and the second stress applying portion 75. The first stress applying portion side portion extends in the side surface direction of the cylindrical portion 71 from the tip end portion. When the opening force is applied to the first stress applying part 74 in a direction away from the second stress applying part 75, the breakable part 76 is broken, and subsequently, the first stress applying part 74 is By tilting, the first engaging portion 77b comes close to the second engaging portion 78b, and the tip of the second engaging portion 78b eventually enters the through hole 83 of the first engaging portion 77b. Then, the two engage with each other. Then, the first engaging portion 77 b and the second engaging portion 78 b are engaged, so that the cylindrical portion 71 holds the first stress applying portion 74, and thereby the first engaging portion 74. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 71 is maintained.

Moreover, as a chemical | medical agent container of this invention, what is shown to FIG. 44 and FIG. 45 may be sufficient. The basic configurations of the drug container 7c and the medical container hollow body 70c of this embodiment are the same as those of the drug container 7 and the medical container hollow body 70 described above. The main difference between the two is the first relationship. It is the structure of a joint part and a 2nd engaging part. In this embodiment, the medical container hollow body 70 c includes a cylindrical member 81 that encloses the cylindrical portion, and the first engagement portion 77 c is a protrusion formed on the first stress applying portion 74. The second engaging portion 78c is provided at the distal end portion of the cylindrical member 81, and is formed by a recess that engages with the protrusion. The first engaging portion 77c and the second engaging portion 78c of this embodiment are the first described with reference to the discharge port 3c and the medical container hollow body 30c shown in FIGS. The engaging portion 37c and the second engaging portion 38c have the same configuration. The tubular member 81 may be formed integrally with the tubular portion 71.
The medical container hollow body 70c of this embodiment includes a cylindrical member 81 that encloses an intermediate portion of the cylindrical part 71 of the medical container hollow body 70c.
In the discharge port 7c and the medical container hollow body 70c of this embodiment, as shown in FIGS. 44 and 45, the first stress applying part 74 includes a first engaging part 77c. Then, the breakable portion 76 is broken at the distal end portion of the cylindrical member 81 due to the spread between the first stress applying portion 74 and the second stress applying portion 75, and after the opening of the cylindrical portion 71, A recess is provided that constitutes a second engagement portion 78 c that engages with the engagement portion 77 c and holds the first stress applying portion 74.
In the medical container hollow body 70c of this embodiment, the breakable portion 76 is provided only on the first stress applying portion 74 side having the first engaging portion 77c, and the first engaging portion 77c. And the 2nd engaging part 78c is provided so that it may oppose via the breakable part 76 (specifically, it faces the axial direction of a cylindrical part via the breakable part 76). One of the first engaging portion and the second engaging portion is a protrusion, and the other is a recess that houses and holds the protrusion.
In the medical container hollow body 70c of this embodiment, as shown in FIG. 45, the first engaging portion 77c provided in the first stress applying portion 74 is provided in a portion close to the breakable portion 76. And a rib projecting in the side surface direction at the tip. Moreover, the front end surface of this protrusion is an inclined surface which inclines toward the front end direction.
As shown in FIGS. 44 and 45, the tubular member 81 encloses the tubular portion 71 of the medical container hollow body 70 c and has a distal end portion that reaches the breakable portion 76. . Then, a second engaging portion 78c formed by a concave portion that holds the first engaging portion (projection) 77c provided in the first stress applying portion 74 and holds the stored protrusion at the tip portion. It has. Therefore, in this embodiment, the second engagement portion 78 c is formed by the tip end portion and the concave portion of the cylindrical member 81. And the 1st engaging part 77c can enter into the recessed part which comprises the 2nd engaging part 78c, and a rib engages with the edge of a recessed part after approaching.

And also in the hollow body 70c for medical containers of this Example, the 1st stress application part 74 and the 2nd stress application part 75 are provided with the flat parts 74a and 75a for adhering to the inner surface of a soft bag, The first engaging portion 77c and the second engaging portion 78c are formed so as to be positioned on an extension line in the axial direction of the hollow medical container hollow body 70c. Therefore, by fixing the medical container hollow body 70c to the inner surface of the flat portion soft bag of the first stress applying portion 74 and the second stress applying portion 75, the first engaging portion 77c is also made of the soft bag. It faces the inner surface in the vicinity of the adhering portion, and when the medicine chamber 11 of the medical container 1 is pressed, the breakable portion 76 is broken, the first stress applying portion 74 is inclined, and the first engaging portion 77c is second. The movement in the direction of the engaging portion 78c is ensured.
In the medical container hollow body 70c of this embodiment, the breakable portion 76 includes a distal end portion provided so as to pass between the first stress applying portion 74 and the second stress applying portion 75. The first stress applying portion side portion extends in the side surface direction of the cylindrical portion 71 from the tip end portion. When the opening force is applied to the first stress applying part 74 in a direction away from the second stress applying part 75, the breakable part 76 is broken, and subsequently, the first stress applying part 74 is By tilting, the first engaging portion 77c approaches the second engaging portion 78c, and the end portion of the first engaging portion 77c eventually enters the recess of the second engaging portion 78c. , Both engage. Then, the first engaging portion 77c and the second engaging portion 78c are engaged, so that the cylindrical portion 71 holds the first stress applying portion 74, whereby the first engaging portion 74 is retained. The movement in the direction of the second engagement portion is restricted, and the open state of the cylindrical portion 71 is maintained.

The medical container of the present invention may be as shown in FIG.
The medical container 40 of this embodiment includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a drug solution in the drug chamber 11 attached to the soft bag 2. And a medicine container 7 containing medicine for mixing, and a discharge port 10 attached to the soft bag 2. As the medicine container 7, the above medicine container 7 using the medical container hollow body 70 of the present invention is used.
A part of the flat plate portion 74a of the first stress applying portion 74 of the medical container hollow body 70 is fixed to the inner surface of one sheet 2a forming the drug chamber 11 of the soft bag 2, and the second A part of the flat plate portion 75 a of the stress applying portion 75 is fixed to the inner surface of the other sheet 2 b forming the drug chamber 11 of the soft bag 2, and the breakable portion 76 is the soft bag 2 when the drug chamber 11 is pressed. The first stress applying portion 74 and the second stress applying portion 75 that are fixed to each other are broken and the inside of the medicine container 7 is communicated with the medicine chamber 11.
Also in the drug container 7 of this embodiment, the medical container hollow body 70 is similar to the one shown in FIG. 37 in that the breakable portion 76 includes the first stress applying portion 74 and the second stress applying portion. It has a tip side part provided so as to pass between the part 75 and a first stress applying part side part extending in the side surface direction of the cylindrical part 71 from the tip side part. When the medicine chamber 12 is pressed, the vicinity of the fixing portion of the first stress applying portion 74 to the soft bag 2 swells, and the first stress applying portion 74 is pulled, whereby the first stress applying portion 74 is When the opening force is applied in a direction away from the second stress applying portion 75, the breakable portion 76 is broken, and subsequently, the first engaging portion 77c approaches the second engaging portion 78c. Eventually, both engage. And the cylindrical part 71 hold | maintains the 1st stress provision part 74 by the 1st engagement part 77c and the 2nd engagement part 78c engaging, Thereby, the 1st stress provision part 74 is obtained. The movement in the direction of the second stress applying portion is restricted, and the open state of the cylindrical portion 71 is maintained.

Similarly to the medical container 20 described above, the medical container 40 of this embodiment is also provided in the soft bag 2 in the vicinity of the drug chamber side tip of the drug container 7, as shown in FIG. A peelable spread suppressing inter-sheet fixing portion 25 for suppressing spread between sheets fixed by the first stress applying portion and the second stress applying portion is provided. As the expansion suppressing inter-sheet fixing portion 25, the same one as the above-described expansion suppressing inter-sheet fixing portion is suitable. In addition, the medical container 40 of this embodiment is also provided in the first drug chamber 11 and the second drug chamber 12 from the soft seal 2 to the soft bag 2 and from the removable weak seal portion 9 for separation, similarly to the medical container 20 described above. It is partitioned. The partition weak seal portion 9 is preferably the same as described above.
Moreover, in the medical container 40 of this Example, as shown in FIG. 46, the lower end side seal part 6 of the soft bag 2 has the discharge port 10. As the discharge port 10, it is preferable to use a known one as shown in FIG. 46, and for example, it is preferable to include a cylindrical port member and a seal member that seals the opening and can be inserted through the needle tube.
Furthermore, in the medical container 40 of this embodiment, as shown in FIG. 46, the soft bag 2 includes a communication inhibiting weak seal portion 26 that inhibits communication between the discharge port 10 and the first drug chamber 11. Yes.
The communication-inhibiting weak seal portion 26 is formed so as to surround the upper portion of the discharge port 10. A small chamber 27 isolated from the first drug chamber 11 is formed by the weak seal portion 26 for inhibiting communication. This small room 27 is an empty room in the embodiment of the present invention. However, the small chamber 27 may contain a predetermined liquid (for example, physiological saline). The small chamber 27 may be in a dry state, but may be filled with a small amount of liquid for sterilization. Further, a passage through which some water vapor or medicine passes through the communication inhibiting weak seal portion 26 may be formed so as to communicate with the small chamber 27 at the above-described level. The weak seal portion 26 for inhibiting communication can be formed by heat-sealing the sheet material in a band shape (thermal fusion, high frequency fusion, ultrasonic fusion, etc.).
In the embodiment shown in FIG. 46, the communication inhibiting weak seal portion 26 is formed in an inverted U-shape. Further, the weak seal portion 26 for inhibiting communication has a trapezoidal shape with the short side on the upper side, a triangular shape with the discharge port at the top, a triangular shape with the discharge port at the bottom, a polygonal shape such as a quadrangle, a substantially semicircular shape, A substantially semi-elliptical shape may be used.

And in the medicine containers of all the embodiments described above, as shown in FIGS. 52 and 53, the breakable portion 76 is a portion provided between the first engaging portion 77 and the second engaging portion 78. It may be provided with a target breakable portion missing portion 65. 52 is a front view of another embodiment of the medical container for medical containers of the present invention, and FIG. 53 is a hollow body for medical containers used in the medical container for medical containers shown in FIG. It is an expanded sectional view of the 1st engaging part and 2nd engaging part vicinity.
The breakable part 76 of the drug container 7d (medical container hollow body 70d) of this embodiment is formed so as to surround the proximal end part of the first stress applying part 74 or the second stress applying part 75, In addition, a partially breakable portion missing portion 65 located between the first engaging portion 77 and the second engaging portion 78 is provided. And the defect | deletion part 65 forms the plastically deformable part. Then, the first stress applying portion or the second stress applying portion is not separated from the hollow body 70d by the defect portion 65.
Specifically, in this embodiment, the breakable portion 76 is the distal end portion of the tubular portion 71 as shown in FIG. 52, and the proximal end portion and the tubular portion of the first stress applying portion 74. And having a starting end and a terminal end, it is formed in a substantially annular shape. A breakable portion missing portion 65 is formed between the start end and the end of the breakable portion 76. The breakable portion 76 is provided on only one of the first stress applying portion 74 and the second stress applying portion 75 (in this embodiment, only on the first stress applying portion 74 side). Although the defect portion 65 is plastically deformed, it does not break in the widening operation (breaking operation of the breakable portion 76) between the first stress applying portion 74 and the second stress applying portion 75. Therefore, the first stress applying part 74 having the breakable part 76 is a hollow body 70d in the widening operation (breaking operation of the breakable part 76) between the first stress applying part 74 and the second stress applying part 75. It has become less segregated. The width of the defect portion 65, in other words, the distance between the start end and the end end of the breakable portion 76 is preferably about 4 to 9 mm, and particularly preferably 6 to 8 mm. In the case where the partially breakable portion missing portion 65 is provided, the material for forming the hollow body, particularly the forming material for the partially breakable portion missing portion, has a tensile elongation (breaking elongation) of 20% or more. Preferably there is. The thickness of the plastically deformable portion is preferably 1.0 to 1.5 mm.

1, 20, 40 Medical container 2 Soft bag 3 Discharge port 7 Drug container 30 Hollow body 34 for medical container First stress applying part 35 Second stress applying part 36 Breakable part 37 First engaging part 38 Second engaging part

Claims (13)

A hollow body for a medical container used for a medical container provided with a soft bag, the hollow body being formed of a hard or semi-rigid material, and the hollow body having a cylindrical shape with a closed end portion And a breakable portion provided at the tip of the tubular portion, and a second portion that is provided so as to sandwich the breakable portion of the tubular portion and can be fixed to the inner surface of one sheet of the flexible bag. And a second stress applying portion that can be fixed to the inner surface of the other sheet of the soft bag, and the breakable portion includes the first stress applying portion and the second stress. The cylindrical portion is broken by spreading between the applying portions, and the cylindrical portion is opened. The first stress applying portion or the second stress applying portion includes a first engaging portion, and the cylindrical portion Are the first stress applying part and the second stress. The breakable part is broken by spreading between the given parts, and after the opening of the cylindrical part, the first engaging part is engaged with the first stress applying part or the second stress applying part. A hollow body for a medical container having a second engaging portion to be held. A hollow body for a medical container used for a medical container provided with a soft bag, the hollow body being formed of a hard or semi-rigid material, and the hollow body having a cylindrical shape with a closed end portion And a breakable portion provided at the tip of the tubular portion, and a second portion that is provided so as to sandwich the breakable portion of the tubular portion and can be fixed to the inner surface of one sheet of the flexible bag. A second stress applying portion that can be fixed to the inner surface of the other sheet of the soft bag, and a cylindrical member that is provided so as to enclose the cylindrical portion, and further includes the breakage The possible portion is a portion that breaks due to the spread between the first stress applying portion and the second stress applying portion, and opens the cylindrical portion, and the first stress applying portion or the second stress is provided. The imparting portion includes a first engagement portion, and the tube The member breaks the breakable portion by spreading between the first stress applying portion and the second stress applying portion, and engages with the first engaging portion after opening the cylindrical portion, A hollow body for a medical container, comprising a second engaging portion that holds the first stress applying portion or the second stress applying portion. The hollow body for a medical container according to claim 1 or 2, wherein the first engaging portion and the second engaging portion are provided so as to face each other via the breakable portion. One of the first engaging part and the second engaging part is a protrusion, and the other is a protruding part having a claw part engaging with the protrusion at a tip part. A hollow body for a medical container according to claim 1. One of the first engagement portion and the second engagement portion is a protrusion having a through hole, and the other is a protrusion having a tip portion that enters and engages in the through hole. The hollow body for medical containers according to any one of 1 to 3. The said 1st engaging part is protrusion, The said 2nd engaging part is provided in the front-end | tip part of the said cylindrical member, and is formed of the recessed part engaged with the said protrusion. Hollow body for medical containers. The first stress applying part and the second stress applying part include a flat part for fixing to the inner surface of the soft bag, and the first engaging part and the second engaging part are The hollow body for a medical container according to any one of claims 1 to 6, wherein the hollow body for a medical container is formed so as to be positioned on an extension line in an axial direction of the hollow body for a medical container in a flat portion. The medical container hollow body according to any one of claims 1 to 7, wherein the medical container hollow body having an open rear end portion, the rear end portion of the hollow body being sealed, and a medical use hollow body. A discharge port for a medical container having a sealing portion to which a needle tube can be connected. The medical container discharge port according to claim 8, wherein a medicine is stored in the cylindrical member of the medical container discharge port. Stored in the hollow body of the medical container discharge port are a drug and a needle tube entry inhibiting member that inhibits the medical needle tube from entering the hollow body when the breakable portion is not broken. The discharge port for medical containers according to claim 9. The medical container hollow body according to any one of claims 1 to 7, wherein the medical container hollow body has one open end, a sealing member that seals the one end of the hollow body, A drug container for medical containers, comprising a drug stored in a hollow body. A medical container comprising a soft bag, a drug chamber formed in the soft bag, a drug solution filled in the drug chamber, and a discharge port attached to the soft bag, the discharge port comprising: 11. The discharge port according to claim 8, wherein a part of an outer surface of the first stress applying portion is fixed to an inner surface of one sheet forming the drug chamber of the soft bag. And a part of the outer surface of the second stress applying portion is fixed to the inner surface of the other sheet forming the drug chamber of the soft bag, and the breakable portion is formed when the drug chamber is pressed. A medical container that breaks due to expansion of the first stress applying portion and the second stress applying portion fixed to the soft bag and communicates the inside of the discharge port with the drug chamber. . A soft bag, a drug chamber formed in the soft bag, a drug solution filled in the drug chamber, a drug container attached to the soft bag and containing a drug for mixing with the drug solution, and the soft bag A medical container comprising a discharge port attached to a bag, wherein the drug container is the drug container according to claim 11, and a part of an outer surface of the first stress applying part is the soft container. A part of the outer surface of the second stress applying portion is fixed to the inner surface of the other sheet forming the drug chamber of the soft bag, and is fixed to the inner surface of one sheet forming the drug chamber of the bag. The breakable portion is broken by the spread of the first stress applying portion and the second stress applying portion fixed to the soft bag when the drug chamber is pressed, and the inside of the drug container is Communicate with the drug room Medical container, characterized in that those.

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