JP5535722B2 - Medical container - Google Patents

Description

  The present invention relates to a medical container capable of adjusting and blending a drug in a drug solution such as an infusion solution.

The medical container has a closed tip and a cylindrical body that can be opened. Examples of the cylindrical body include a discharge port used at the time of administration of a drug solution and a drug container that stores a drug added to the drug solution in the medical container.
Prior to infusion of the patient, mix and dissolve drugs that are difficult to pre-mix into the infusion, such as vitamins and antibiotics, in a vial or soft bag containing the infusion. The preparation of chemicals has been carried out. In order to prepare such a chemical solution aseptically and with a simple operation, a drug container containing a drug mixed with the chemical solution is attached to a soft bag containing the chemical solution, and the drug container is infused during infusion. A medical container has been proposed in which a fragile portion provided is bent and broken through a soft bag so that the drug container and the soft bag communicate with each other to mix the drug and the drug solution.

The present applicant has proposed JP-A-2006-87904 (Patent Document 1).
The drug container or discharge port of Patent Document 1 is a drug container or discharge port that can be opened and has a closed tip, and can reliably separate the drug container or discharge port from the medical container. In addition, the medicine container or the discharge port can be communicated with the medical container easily and reliably when necessary. As shown in FIGS. 32 to 37, the drug container 100 of Patent Document 1 is formed of a hard or semi-rigid material, and further has a cylindrical portion 7 with a closed end portion, and at least the distal end of the cylindrical portion 7. The first stress applying portion 59 and the soft bag that are provided so as to sandwich the breakable portion 58 provided in the portion and the breakable portion 58 of the tubular portion 7 and are fixed to one inner surface of the soft bag 2 2 and the second stress applying portion 60 fixed to the other inner surface, and the breakable portion 58 can be broken and broken by spreading between the first stress applying portion 59 and the second stress applying portion 60. The front end side portion is separated from the portion 58 and the cylindrical portion 7 is opened.

Further, as shown in FIGS. 38 to 42, the discharge port 86 of Patent Document 1 is formed of a hard or semi-rigid material, and further includes a cylindrical portion 88 whose tip is closed, and a cylindrical portion 88. A first stress applying portion 89 which is provided so as to sandwich at least the breakable portion 91 provided at the tip portion and the breakable portion 91 of the tubular portion 88 and is fixed to one inner surface of the soft bag 2; A second stress applying portion 90 fixed to the other inner surface of the soft bag 2, and the breakable portion 91 is broken by the spread between the first stress applying portion 89 and the second stress applying portion 90. The front end side portion is separated from the breakable portion 91 and the cylindrical portion 88 is opened.
However, as shown in FIG. 29 of Patent Document 1, the breakable portion 58 or the discharge port 86 of the drug container 100 is pressed by pressing the soft bag 2 of the medical container 1 and 85 including the drug container 100 and the discharge port 86. When the breakable portion 91 is broken and the first stress applying portion side portion and the second stress applying portion side portion are separated from the breakable portions 58, 91, the opening of the tubular portion formed by the break is formed. Although rare, it is feared that it will be blocked again by the separated member.
Therefore, the present applicant has proposed JP-A-2006-280390 (Patent Document 2).
The medical container of Patent Document 2 is a medical container 1 including a soft bag 2 having a drug room, a chemical solution, and a cylindrical body, and the cylindrical body includes a cylindrical portion, a breakable portion, The first and second stress applying portions 34 and 36 are provided so as to sandwich the breakable portion and fixed to the inner surface of the soft bag, and the breakable portion includes first and second stress applying portions 34, It breaks and opens due to the spread of 36. Further, the container 1 extends to the distal end side so as to get over the outer surface of the proximal end portion of the breakable portion, and the proximal end portion 33a of the first stress applying portion side separating portion 33 and the second stress applying portion side separation after the breaking. An extension portion for holding a post-breaking stress applying portion that holds the base end portion 35a of the portion 35 between the inner surface of the soft bag is provided.

JP 2006-87904 A JP 2006-280390 A

Even the thing of the patent document 2 mentioned above has a sufficient effect, but the base end part 33a of the first stress applying part side separating part 33 after breaking and the base end part 35a of the second stress applying part side separating part 35 are provided. In some rare cases, the holding state may be released during the operation of holding the post-breaking stress applying part holding extension part and then hanging it on the stand.
Therefore, the present invention solves the above-described problems, a cylindrical portion whose tip is closed, a breakable portion provided at least at the tip of the cylindrical portion, and a breakable portion of the cylindrical portion A first stress applying portion that is fixed to one inner surface of the soft bag and a second stress applying portion that is fixed to the other inner surface of the soft bag 2. A hollow body for a medical container having a breakable portion that is broken by spreading between the stress applying portion and the second stress applying portion, and the opening formed by the breakage of the breakable portion is separated from the tubular portion It is an object of the present invention to provide a medical container using a hollow body for a medical container that is very unlikely to be closed again by the first stress applying part or the second stress applying part.

What achieves the above object is as follows.
(1) A medical container comprising a soft bag, a drug solution chamber formed in the soft bag, a drug solution filled in the drug solution chamber, and a discharge port attached to the soft bag, the discharge The port is formed of a hard or semi-rigid material, and has a hollow body whose front end portion is closed and a rear end portion is opened, and the rear end portion of the hollow body is sealed, and a medical needle tube can be connected. The hollow body is provided so as to sandwich the tubular part with the closed end part, the breakable part provided in the tubular part, and the breakable part of the tubular part, respectively. A first stress applying portion that can be fixed to the inner surface of one sheet of the soft bag and a second stress applying portion that can be fixed to the inner surface of the other sheet of the soft bag, and the breakable portion is , The first stress applying part and the second stress The hollow body is broken by spreading between the given portions and opens the cylindrical portion, and the first stress applying portion and the second stress applying portion are formed in the hollow body after the breakable portion is broken. The breakable portion has a start end and a terminal end at a base end portion of the first stress applying portion or the second stress applying portion, and the breakable portion is formed of the cylinder. A distal end portion provided at a distal end portion of the shaped portion and passing between the first stress applying portion and the second stress applying portion; and the tubular portion from the distal end portion. A stress applying part side portion extending obliquely in the side surface direction and the rear end direction, and the hollow body is formed between the start end and the terminal end of the breakable part, and the first stress applying part The space between the second stress applying portions expands, and the plastic deformation occurs after the breakable portion breaks. And a plastically deformable portion that maintains a state in which the space between the first stress applying portion and the second stress applying portion is expanded, and the distal end portion of the outer surface of the first stress applying portion is the soft Fixed to the inner surface of one sheet forming the chemical chamber of the bag, and the tip of the outer surface of the second stress applying section is fixed to the inner surface of the other sheet forming the chemical chamber of the soft bag The breakable portion is broken by the spread of the first stress applying portion and the second stress applying portion fixed to the soft bag when the chemical chamber is pressed, and the inside of the discharge port A medical container that communicates with the chemical chamber.

  (2) The medical container according to (1), wherein a medicine is stored in the cylindrical portion of the medical container discharge port.
  (3) In the hollow body of the medical container discharge port, a medicine and a needle tube intrusion inhibiting member that inhibits the medical needle tube from entering the hollow body when the breakable portion is not broken are stored. The medical container according to (1) above.

Moreover, what achieves the said objective is as follows.
(4) a soft bag, a drug solution chamber formed in the soft bag, a drug solution filled in the drug solution chamber, a drug container that is attached to the soft bag and contains a drug for mixing with the drug solution; A medical container comprising a discharge port attached to the soft bag, wherein the drug container is formed of a hard or semi-rigid material and has an open end, and the one end of the hollow body. A sealing member that seals and a medicine housed in the hollow body, the hollow body having a cylindrical part with a closed end, a breakable part provided in the cylindrical part, A first stress applying portion that is provided so as to sandwich the breakable portion of the cylindrical portion and can be fixed to the inner surface of one sheet of the soft bag, and a first stressable portion that can be fixed to the inner surface of the other sheet of the soft bag. 2 stressing portions and The breakable portion is ruptured by spreading between the first stress applying portion and the second stress applying portion, opening the tubular portion, and the first stress applying portion. The part and the second stress applying part are not separated from the hollow body after the breakable part is broken, and the breakable part is the first stress applying part or the second stress applying part. The base end portion has a start end and a terminal end, and the breakable portion is provided at a tip end portion of the cylindrical portion, and the first stress applying portion and the second stress applying portion A front end side portion provided so as to pass through, a stress applying portion side portion extending obliquely from the front end side portion in a side surface direction and a rear end direction of the cylindrical portion, The first stress application is formed between the start end and the end of the breakable portion. Between the first stress applying part and the second stress applying part, and the plastic deformable part maintaining a state in which the first stress applying part and the second stress applying part are expanded. Furthermore, the front-end | tip part of the outer surface of the said 1st stress application part is being fixed to the inner surface of one sheet | seat which forms the said chemical | medical solution chamber of the said soft bag, and the outer surface of the said 2nd stress application part The tip portion of the soft bag is fixed to the inner surface of the other sheet forming the chemical solution chamber, and the breakable portion is the first stress fixed to the soft bag when the chemical solution chamber is pressed. A medical container that is broken by spreading of the applying part and the second stress applying part, and communicates the inside of the drug container with the drug solution chamber.

  (5) The breakable portion is formed so as to surround a proximal end portion of the first stress applying portion or the second stress applying portion, and the first stress applying portion or the second stress applying portion. A partial breakable breakage portion at the proximal end of the stress applying portion, and the plastic deformation deformable portion is formed by the defect portion, and the composition deformable portion is provided by the composition deformable portion The medical container according to any one of (1) to (4), wherein the first stress applying part or the second stress applying part is not allowed to be separated from the hollow body.

  (6) The medical use according to any one of (1) to (5), wherein the breakable portion is provided only in one of the first stress applying portion and the second stress applying portion. container.

  (7) The first stress applying part and the second stress applying part include a flat part for fixing to the inner surface of the soft bag, and the plastically deformable part is the medical container of the flat part. The medical container according to any one of the above (1) to (6), which is formed so as to be positioned on an extension line in the axial direction of the hollow body for use.

The medical container provided with the soft bag of the present invention uses a hollow body. The hollow body is made of a hard or semi-rigid material, and the hollow body has a cylindrical portion with a closed end, a breakable portion provided at the distal end of the tubular portion, and a breakable portion of the tubular portion. A first stress applying portion that can be fixed to one inner surface of the soft bag and a second stress applying portion that can be fixed to the other inner surface of the soft bag. The breakable part is a part that breaks due to the spread between the first stress applying part and the second stress applying part and opens the cylindrical part. Furthermore, the first stress applying part and the second stress applying part Is not separated from the hollow body after the breakable portion is broken. Further, the breakable part has a start end and a terminal end at a base end part of the first stress applying part or the second stress applying part, and is formed between the start end and the terminal end of the breakable part, There is a plastically deformable portion that expands between the applying portion and the second stress applying portion, undergoes plastic deformation after the breakable portion breaks, and maintains a state in which the first stress applying portion and the second stress applying portion are expanded. doing. For this reason, according to the hollow body for a medical container, the space between the first stress applying portion and the second stress applying portion expands, and after the breakable portion is broken, the first stress is applied by the plastically deformable portion. Since the state in which the space between the part and the second stress applying part is expanded is maintained, the opening formed by the break of the breakable part is closed again by the first stress applying part and the second stress applying part. Is surely prevented.

FIG. 1 is a front view of an embodiment of the medical container of the present invention. FIG. 2 is a front view of an embodiment of the discharge port used in the medical container of the present invention. FIG. 3 is a cross-sectional view taken along line AA in FIG. 4 is an enlarged sectional view taken along line BB in FIG. FIG. 5 is a front view of an embodiment of a hollow body used in the medical container of the present invention. FIG. 6 is a right side view of a hollow body used in the medical container shown in FIG. FIG. 7 is a perspective view of a hollow body used in the medical container shown in FIG. FIG. 8 is an enlarged plan view of a hollow body for use in the medical container shown in FIG. FIG. 9 is a front view of an example of the needle tube entry inhibiting member housed in the discharge port of the medical container of the present invention. FIG. 10 is a right side view of the needle tube penetration inhibiting member shown in FIG. FIG. 11 is an enlarged plan view of the needle tube entry inhibiting member shown in FIG. FIG. 12 is an enlarged bottom view of the needle tube entry inhibiting member shown in FIG. FIG. 13 is a perspective view of the needle tube entry inhibiting member shown in FIG. FIG. 14 is a perspective view of a hollow body attaching member used in the medical container of the present invention. FIG. 15 is an explanatory diagram for explaining the operation of the discharge port of the medical container and the hollow body of the medical container of the present invention. FIG. 16 is an explanatory diagram for explaining the operation of the medical container of the present invention. FIG. 17 is a side view of another embodiment of the discharge port used in the medical container of the present invention. FIG. 18 is an explanatory diagram for explaining the operation of the discharge port of the medical container shown in FIG. FIG. 19 is an explanatory diagram for explaining the operation of the medical container using the discharge port of the medical container shown in FIG. FIG. 20 is a front view of another embodiment of the medical container of the present invention. FIG. 21 is a front view of an embodiment of a drug container used in the medical container of the present invention. 22 is a cross-sectional view taken along the line CC of FIG. FIG. 23 is a front view of another embodiment of the medical container of the present invention. FIG. 24 is a front view of another embodiment of the medical container of the present invention. FIG. 25 is a front view of another embodiment of the medical container of the present invention.

The hollow body for medical containers, the medicine container for medical containers, the discharge port for medical containers, and the medical container of the present invention will be described with reference to the embodiments shown in the drawings.
The medical container hollow body 30 of the present invention is a medical container hollow body used for the medical container 1 including the soft bag 2. The hollow body 30 is formed of a hard or semi-rigid material. Further, the hollow body 30 includes a cylindrical portion 32 whose tip is closed, and a breakable portion 36 provided at the tip of the cylindrical portion 32. The first stress applying portion 34 that is provided so as to sandwich the breakable portion 36 of the cylindrical portion 32 and can be fixed to the inner surface of one sheet 2a of the soft bag 2 and the inner surface of the other sheet 2b of the soft bag 2 And a second stress applying portion 35 that can be fixed to the head. The breakable part 36 breaks due to the spread between the first stress applying part 34 and the second stress applying part 35 and opens the cylindrical part 32. Furthermore, the first stress applying part 34 and the second stress applying part 34 The stress applying part 35 of 2 is not separated from the hollow body 30 after the breakable part 36 is broken. Furthermore, the breakable part 36 has a start end and a terminal end at the base end part of the first stress applying part 34 or the second stress applying part 35, and is formed between the start end and the terminal end of the breakable part 36, A state in which the space between the first stress applying portion 34 and the second stress applying portion 35 is expanded, the plastic deformation is performed after the breakable portion 36 is broken, and the space between the first stress applying portion 34 and the second stress applying portion 35 is expanded. It has a plastically deformable portion 37 that maintains the above.
Here, “maintaining a state where the first stress applying portion 34 and the second stress applying portion 35 are expanded” means that the plastic deformation state, in other words, the breakable portion is broken and the hollow body It shows what maintains the state which 30 cylindrical parts 32 opened, and is not limited to what maintains the initial shape (initial state) at the time of plastic deformation completely. The plastically deformable part 37 is a part that can be plastically deformed by spreading between the first stress applying part 34 and the second stress applying part 35 and can maintain the plastically deformed state. In other words, it can be called a deformed state maintaining portion.

Moreover, the discharge port 3 for medical containers of this invention is the hollow body for medical containers of this invention, and the rear end part of the hollow body 30 which the rear-end part opened, and the rear-end part of the hollow body 30 is sealed, and medical And a sealing portion capable of connecting a needle tube.
The medical container 7 for medical containers of the present invention includes a hollow body 70 for medical containers of the present invention, a sealing member 72 that seals the opening of the hollow body 70, and a drug 73 stored in a cylindrical portion. It has.
The medical container 1 of the present invention includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a discharge port 3 attached to the soft bag 2. Is provided. And as the discharge port 3, the discharge port using the hollow body for medical containers of this invention is used.
The medical container 60 of the present invention includes a soft bag 2, a drug chamber (medicine solution chamber) 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a drug attached to the soft bag 2. A drug container 7 in which a drug for mixing with the drug solution in the chamber 11 is stored, and a discharge port 3 attached to the soft bag 2 are provided. And as the medicine container 7, the medicine container 7 using the hollow body for medical containers of the present invention is used.

First, a medical container hollow body according to the present invention applied to a medicine container / discharge port and a medical container using the same will be described.
The medical container 1 of this embodiment includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a discharge port 3 attached to the soft bag 2. Prepare. The discharge port 3 is a discharge port using the medical container hollow body of the present invention, and a part of the outer surface of the first stress applying portion 34 forms the drug chamber 11 of the soft bag 2. A part of the outer surface of the second stress applying portion 35 is fixed to the inner surface of the other sheet 2b forming the drug chamber 11 of the soft bag 2, and the breakable portion 36 is fixed to the inner surface of the second sheet 2a. Is broken by the expansion of the first stress applying portion 34 and the second stress applying portion 35 fixed to the soft bag 2 when the drug chamber 11 is pressed, and the inside of the discharge port 3 is communicated with the drug chamber 11. is there.
The medical container 1 of this embodiment is formed of a flexible material, and includes a soft bag 2 having a drug chamber 11 serving as a drug storage portion therein, and a medical container attached to the drug chamber 11 of the soft bag 2. It is a medical container containing a medicine provided with a discharge port 3 and a medicine liquid filled in the medicine chamber 11.
As shown in FIG. 1, seal portions 5 and 6 are provided on one end side and the other end side of the soft bag 2.

The soft bag 2 of the medical container 1 is made of a soft synthetic resin. The flexible bag 2 is preferably formed into a cylindrical shape by an inflation molding method. The soft bag 2 may be manufactured by various methods such as a blow molding method and a coextrusion inflation method.
The soft bag 2 preferably has a water vapor barrier property. As the degree of water vapor barrier property, the water vapor permeability is preferably 50 g / m ² · 24 hrs · 40 ° C. · 90% RH or less, more preferably 10 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. More preferably, it is 1 g / m ² · 24 hrs · 40 ° C. · 90% RH or less. This water vapor permeability is measured by the method described in JISK7129 (Method A). Thus, since the soft bag 2 has a water vapor barrier property, transpiration of water from the inside of the medical container 1 can be prevented. As a result, it is possible to prevent reduction and concentration of the medicine (specifically, chemical solution) to be filled. Moreover, the invasion of water vapor from the outside of the medical container 1 can be prevented.

Examples of the material for forming such a flexible bag 2 include various types such as polyethylene (PE), polypropylene (PP), polybutadiene, polyolefins such as ethylene-vinyl acetate copolymer (EVA), olefin elastomers, and styrene elastomers. Thermoplastic elastomers or those arbitrarily combined (blend resin, polymer alloy, laminate, etc.) can be mentioned. And it is preferable that the resin material to be used has the heat resistance and water resistance which can endure high pressure steam sterilization (autoclave sterilization).
In the present invention, it is preferable that the material for forming the soft bag 2 includes polyolefin. As a material for forming the flexible bag 2, polyethylene or polypropylene, a styrene thermoplastic elastomer such as a styrene-butadiene copolymer or a styrene-ethylene-butylene-styrene block copolymer, or an ethylene-propylene copolymer is particularly preferable. And a soft resin obtained by blending and softening an olefin-based thermoplastic elastomer such as an ethylene-butene copolymer or a propylene-α-olefin copolymer. This material is preferable in that it has high strength and flexibility, heat resistance (particularly heat resistance during sterilization) and water resistance, and is particularly excellent in workability and can reduce manufacturing costs.

The soft bag may have a single-layer structure (single-layer body) made of the materials described above, or a multilayer in which a plurality of layers (particularly layers of different materials) are stacked for various purposes. A laminated body may be sufficient. In the case of a multilayer laminate, a plurality of resin layers may be stacked, or a metal layer may be stacked on at least one resin layer. In the case where a plurality of resin layers are stacked, the advantages of the respective resins can be provided together. For example, the impact resistance of the soft bag 2 can be improved, or anti-blocking properties can be imparted. Moreover, in the case of a thing with a metal layer, the gas barrier property etc. of the soft bag 2 can be improved. For example, when a film such as an aluminum foil is laminated, the gas barrier property can be improved and the light shielding property can be imparted. In addition, when a layer made of an oxide such as titanium oxide, aluminum oxide, or silicon oxide is formed, the transparency of the flexible bag 2 can be maintained while improving the gas barrier property, and the internal visibility can be secured. Can do. In addition, when the soft bag 2 is a multilayer laminated body, it is preferable that the material which forms the inner surface part is the material mentioned above.
The thickness of the sheet material constituting the flexible bag 2 is appropriately determined according to the layer configuration and the characteristics of the material used (flexibility, strength, water vapor permeability, heat resistance, etc.), and is not particularly limited. However, usually, it is preferably about 100 to 500 μm, and more preferably about 200 to 360 μm.
Moreover, although the volume of the medical container 1 changes with kinds etc. of the chemical | medical agent accommodated in an inside, it is preferable normally that the volume of a chemical | medical agent chamber is about 50-5000 ml.
The medical container discharge port 3 is for discharging the medicine (chemical solution) filled in the soft bag 2.

The discharge port 3 is fixed to the medicine chamber of the soft bag 2. The discharge port 3 includes a medical container hollow body 30, and the medical container hollow body 30 has a cylindrical portion 32 with a closed end portion and a breakable portion 36 provided at the distal end portion of the cylindrical portion 32. Each of the first stress applying part 34 and the other sheet 2b of the soft bag 2 which are provided so as to sandwich the breakable part 36 of the cylindrical part 32 and can be fixed to the inner surface of one sheet 2a of the soft bag 2. And a second stress applying portion 35 that can be fixed to the inner surface. The breakable portion 36 is broken by the spread between the first stress applying portion 34 and the second stress applying portion 35 and opens the cylindrical portion 32. Furthermore, the breakable part 36 has a start end and a terminal end at the base end part of the first stress applying part 34 or the second stress applying part 35, and is formed between the start end and the terminal end of the breakable part 36, A plastically deformable portion that can be plastically deformed by maintaining a gap between the first stress applying portion 34 and the second stress applying portion 35 and can maintain the plastic deformed state (in other words, a deformable state maintainable portion, a plastically deformed state maintainable) Possible portion) 37.
Further, the discharge port 3 includes a discharge port having a seal member 52 that closes the other end of the cylindrical portion 32 and can be connected to a medical needle tube. Furthermore, in the medical container 1 of this embodiment, the cylindrical portion 32 of the medical container hollow body 30 provided in the medical container hollow body 30 in the discharge port 3 when the breakable portion 36 is not broken is provided in the discharge port 3. A needle tube entry inhibiting member 4 that inhibits the medical needle tube from entering the inside is housed.

The discharge port 3 of this embodiment includes a medical container hollow body 30, a discharge port 50 that seals an opening of the medical container hollow body 30 and allows connection (puncture) of a medical needle, and a discharge A cylindrical attachment member 55 for attaching the port 3 (medical container hollow body 30) to the soft bag 2, the needle tube penetration inhibiting member 4 housed in the medical container hollow body 30, and a medical container hollow And a medical solution 39 filled in the body 30.
The discharge port 50 includes a seal member 52 capable of connecting (puncturing) a medical needle tube, and a cap member 51 for fixing the seal member 52 to the opening of the medical container hollow body 30. Yes. And the cap member 51 is fixed to the fixing | fixed part (flange part 33) provided in the base end part of the hollow body 30 for medical containers by ultrasonic fusion, high frequency fusion, heat fusion, etc. It is preferable that the cylindrical part 32 of the hollow body 30 for medical containers is formed transparent so that an internal medicine can be visually observed. Moreover, although the cylindrical part 32 of the hollow body 30 for medical containers may be a normal pressure, it is good also as a pressure reduction or a vacuum state. As described above, when the medicine container is in a reduced pressure or vacuum state, the effect of preventing degradation / degradation and the like of the medicine is improved.
The medicine 39 to be stored may be any powder, granule or other solid form or liquid form. Drugs are formulated and dissolved in infusions. For example, antibiotics, vitamins (general vitamins), various amino acids, antithrombotics such as heparin, insulin, antitumor agents, analgesics, cardiotonics, statics Note: Anesthetic agents, anti-Parkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, antiviral agents, immunostimulants, and the like.

The discharge port 3 is a non-communication port in a normal state.
As shown in FIGS. 3, 5 to 8, the medical container hollow body 30 includes a cylindrical portion 32 having a hollow portion, a breakable portion 36 provided in the cylindrical portion 32, and a first stress. An application unit 34 and a second stress application unit 35 are provided. The breakable part 36 has a start end and a terminal end at the base end part of the first stress applying part 34 or the second stress applying part 35, and is formed between the start end and the terminal end of the breakable part 36. Between the first stress applying part 34 and the second stress applying part 35 is expanded, and after the breakable part 36 is ruptured, it is plastically deformed and the first stress applying part 34 and the second stress applying part 35 are maintained in an expanded state. It has a plastically deformable part (deformable state maintaining part, plastic deformable state maintaining part) 37. Further, the medical container hollow body 30 includes a first fixing portion 21 (see FIG. 16) in which the first stress applying portion 34 is fixed to the inner surface of one sheet forming the drug chamber 11 of the soft bag 2. The second stress applying portion 35 has a second fixing portion 22 (see FIG. 16) fixed to the inner surface of the other sheet forming the drug chamber 11. As shown in FIGS. 1, 16, 19, 20, 23, 24, and 25, the first fixing portion 21 has a distal end portion of the outer surface of the first stress applying portion 34 of the soft bag 2. The medicine chamber 11 is formed by being fixed to the inner surface of one of the sheets. Similarly, the second fixing portion 22 also forms the medicine chamber 11 at the tip of the outer surface of the second stress applying portion 35. It is formed by fixing to the inner surface of the other sheet. And in the hollow body 30 for medical containers of this Example, the attachment part for attaching the discharge port 50 in which the connection (puncture) of a medical needle tube is possible is formed in the base end part of the cylindrical part 32. FIG. . Further, the base end portion of the cylindrical portion 32 extends a predetermined length from the breakable portion 36 to the base end side.
The breakable portion 36 of the medical container hollow body 30 is broken by the expansion between the first fixing portion 21 and the second fixing portion 22 with the soft bag 2 when the drug chamber 11 is pressed. .

As shown in FIGS. 5 to 7, the cylindrical portion 32 is a cylindrical portion whose front end portion is closed and whose proximal end portion is opened, and a flange portion 33 provided at the proximal end portion and a first cylinder. A taper portion that is continuous with the first cylindrical portion and decreases in a tapered shape toward the distal end side, a second cylindrical portion that is continuous with the tapered portion, and a closing portion that is continuous with the second cylindrical portion (front end) Part). The shape of the tip is preferably a dome shape, a cone shape, or a truncated cone shape, and particularly preferably a dome shape or a truncated cone shape. In this embodiment, the blocking portion has a dome shape.
It is preferable that the volume of the cylindrical part 32 is 1-30 ml. The length of the cylindrical portion is preferably 20 to 100 mm. Further, the base end side of the flange portion is for fixing the cap member 51 that forms the discharge port 50.
The material for forming the hollow body 31 includes rigid polyvinyl chloride, polyethylene, polypropylene, polybutadiene, cyclic polyolefin [specifically, COP (cyclic olefin polymer) such as ZEONEX (registered trademark, manufactured by Nippon Zeon Co., Ltd.), APEL (COC (cyclic olefin copolymer) such as (registered trademark, Mitsui Chemicals, Inc.)], polypropylene homopolymer, polyolefin such as high-density polyethylene, polystyrene, poly- (4-methylpentene-1), polycarbonate, ABS resin , Acrylic resin, polymethyl methacrylate (PMMA), polyacetal, polyarylate, polyacrylonitrile, polyvinylidene fluoride, ionomer, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate (PET), polybuty Examples thereof include polyesters such as terephthalate (PBT), butadiene-styrene copolymers, various resins such as aromatic or aliphatic polyamides, or any combination thereof. Moreover, as a forming material for the hollow body, particularly as a forming material for the plastically deformable portion, the tensile elongation (elongation at break) is preferably 20% or more. The thickness of the plastically deformable portion is preferably 1.0 to 1.5 mm.

In this embodiment, the first stress applying portion 34 and the second stress applying portion 35 extend forward with the vicinity of the breakable portion of the cylindrical portion 32 as the base end, as shown in FIGS. I'm out. The first stress applying unit 34 and the second stress applying unit 35 have a function of converting the force into stress for breaking the breakable portion when a force for opening the both is applied. The first stress applying part 34 and the second stress applying part 35 are preferably formed so as to face each other. Moreover, it is preferable that the main-body part of the 1st stress provision part 34 and the 2nd stress provision part 35 is formed in the vertically long rectangular shape. With such a configuration, when the soft bag 2 is pressed and inflated, the first stress applying part 34 and the second stress applying part 35 reliably apply the breaking stress to the breakable part 36.
Specifically, in the medical container hollow body 30 in the medical container 1 of this embodiment, the first stress applying part 34 and the second stress applying part 35 are as shown in FIGS. Vertically long flat plate portions 34a and 35a and side wall portions formed on both sides of the flat plate portion are provided. The first stress applying part 34 and the second stress applying part 35 are provided so as to extend in the axial direction of the cylindrical part 32. The first stress applying part 34 and the second stress applying part 35 have opposite side wall portions. The first stress applying part 34 and the second stress applying part 35 are provided so as to face each other and be slightly separated from each other. The first stress applying portion 34 and the second stress applying section 35 is located near the center of the flat plate portion 34a, 35 a, ribs 34b extending in the axial direction of the hollow body, and a 35b. The ribs 34b and 35b are not in contact with each other.

The breakable portion 36 may be configured such that when the stress is applied by the first stress applying portion 34 and the second stress applying portion 35, the tip portion of the cylindrical portion 32 can be vertically cut. preferable. The breakable portion 36 is formed so as to surround the proximal end portion of the first stress applying portion 34 or the second stress applying portion 35, and the first stress applying portion 34 or the second stress applying portion The base end portion of 35 is provided with a partially breakable portion missing portion. A plastically deformable portion 37 is formed by the missing portion. The composition deformable portion 37 is constituted by a defective portion and does not allow separation of the first stress applying portion or the second stress applying portion provided with the defective portion from the hollow body. . Specifically, in this embodiment, the breakable portion 36 is the distal end portion of the cylindrical portion 32, as shown in FIGS. 5 and 7, and the proximal end portion of the first stress applying portion 34. Although it has a start end and a terminal end so as to be separated from the cylindrical portion, it is formed in a substantially annular shape. A plastically deformable portion (breakable portion missing portion) 37 is formed between the start end and the end of the breakable portion 36. The breakable portion 36 is provided only on either the first stress applying portion 34 or the second stress applying portion 35 (in this embodiment, only on the first stress applying portion 34 side). . The plastically deformable portion 37 does not break in the widening operation (breaking operation of the breakable portion 36) between the first stress applying portion 34 and the second stress applying portion 35 although it is plastically deformed. Therefore, the first stress applying part 34 having the breakable part 36 has the hollow body 30 in the widening operation (breaking operation of the breakable part 36) between the first stress applying part 34 and the second stress applying part 35. It has become less segregated. The width of the plastically deformable portion 37, in other words, the distance between the start end and the end of the breakable portion 36 is preferably about 4 to 9 mm, and particularly preferably 6 to 8 mm.
And in the hollow body 30 for medical containers of this Example, the 1st stress provision part 34 and the 2nd stress provision part 35 are provided with the flat part for adhering to the inner surface of the soft bag 2, and can be plastically deformed. The part 37 is formed so as to be located on an extension line in the axial direction of the hollow body 30 for a medical container having a flat part. For this reason, by fixing the flat part of the first stress applying part 34 and the second stress applying part 35 to the inner surface of the soft bag 2 in the medical container hollow body 30, the plastically deformable part 37 is also the soft bag 2. Therefore, the fracture of the breakable portion 36 and the plastic deformation of the plastic deformation portion 37 are ensured when the drug chamber 11 of the medical container 1 is pressed.

In the medical container hollow body 30 of this embodiment, as shown in FIG. 6, the breakable portion 36 passes between the first stress applying portion 34 and the second stress applying portion 35. The front-end | tip side part provided and the 1st stress-applying part side part extended diagonally from the front- end | tip side part to the side surface direction and rear-end direction of the cylindrical part 32 are provided. As shown in FIGS. 15 and 16, when the drug chamber 11 is pressed, the vicinity of the fixing portion of the first stress applying portion 34 to the soft bag 2 swells, and the first stress applying portion 34 is pulled. When the opening force is applied to the first stress applying portion 34 in a direction away from the second stress applying portion 35, the breakable portion 36 is broken, and subsequently, the plastically deformable portion 37 is plastic. Deform.
The breakable part 36 is a breakable weak part. Specifically, the breakable part is preferably a thin part. The breakable portion 36 is preferably produced by forming a groove on the outer surface of the tubular portion 32. In this embodiment, the breakable portion 36 is produced by forming a groove portion having a V-shaped cross section. The angle of the groove is preferably 30 to 120 °, particularly 40 to 60 °, and the minimum thickness is preferably 0.05 to 0.3 mm, particularly 0.08 to 0.2 mm. By producing the groove forming portion at such an angle, when the soft bag 2 is inflated, the stress concentrates at the center of the breakable portion, and the groove is reliably broken. Further, the groove portion may have any shape as long as it is easily broken, and is not limited to the V shape as in the embodiment, and may be a semicircular shape, a semielliptical shape, or the like. Moreover, although the breakable part of the present invention can be broken by forming a thin part by forming a groove part, it is not limited to this. The breakable portion may be produced by, for example, forming a portion forming the breakable portion of the medicine storage portion with a material more fragile than the other portions. Specifically, it is preferable that a part forming the breakable part is made of an easily breakable material by multicolor molding, and the other part is made of a material that is not easily broken.
Further, the breakable portion 36 is any material as long as it can break the cylindrical portion 32 (drug storage portion) by the stress applied by the first stress applying portion 34 and the second stress applying portion 35. May be.

  Further, as shown in FIGS. 7 and 8, the first stress applying part 34 and the second stress applying part 35 include flat plate parts 34 a and 35 a that are provided on respective faces facing each other and do not contact each other. Preferably it is. Moreover, it is preferable that the flat part joined to the inner surface of the soft bag 2 is formed in the outer surface of flat plate part 34a, 35a. The flat portion forms a joint surface with the inner surface of the soft bag. In this embodiment, the plane portion is formed from the vicinity of the proximal end portions of the first stress applying portion 34 and the second stress applying portion 35 to the distal end. The flat portion joined to the inner surface of the soft bag 2 is at least partially formed of a material that can be fixed to the inner surface of the soft bag 2. Specifically, the flat part joined to the inner surface of the soft bag 2 is partially or entirely compatible with the forming material of the soft bag 2 (particularly, the forming material forming the inner surface side of the soft bag 2). It is preferably formed of a certain resin. With such a configuration, the first stress applying part 34 and the second stress applying part 35 can be reliably bonded to the inner surface of the flexible bag 2. The resin compatible with the soft bag 2 is preferably the resin described above. The compatible resin is preferably a material that is the same as or similar to the constituent material of the soft bag. In an embodiment of the present invention, it is preferable that all of the first stress applying part or the second stress applying part are made of a resin compatible with the soft bag of the medical container, and the first stress applying part Alternatively, it is more preferable that the second stress applying part and the cylindrical part 32 are all made of a resin compatible with the soft bag of the medical container. Moreover, the compatible resin layer may be produced by two-color molding. The compatible resin layer is preferably made flat so as to be easily joined to the inner surface of the soft bag.

  Further, the first stress applying part 34 and the second stress applying part 35 are formed slightly apart between the first stress applying part 34 and the second stress applying part 35. As described above, the first stress applying part 34 and the second stress applying part 35 are not so separated from each other. For this reason, even if it presses between the 1st stress application part 34 and the 2nd stress application part 35 at the time of fixation to the soft bag 2, it is accept | permitted to the 1st stress application part 34 and the 2nd stress application part 35. The amount of deformation is small and there is no possibility that the breakable portion 36 will break. In the embodiment of the present invention, as shown in FIGS. 6 and 7, the side walls excluding the vicinity of the rear end portions of the flat plate portions 34a and 35a of the first stress applying portion 34 and the second stress applying portion 35 are raised. Thus, the first stress applying part 34 and the second stress applying part 35 are slightly separated from each other by forming protrusions at positions corresponding to the inner surfaces of the side walls.

In the medical container 1, the whole or part of the flat surface portion of the flat plate portion 34 a of the first stress applying portion 34 is joined to the inner surface of the sheet of the flexible bag 2, whereby the first fixing portion 21 ( Similarly, the flat part of the flat plate part 35a of the second stress applying part 35 is joined to the inner surface of the sheet of the flexible bag 2 in the same manner as the second fixing part. 22 (see FIG. 16) is formed. For this reason, the first stress applying part and the second stress applying part follow the spread between the first stress applying part and the fixed part of the second stress applying part of the soft bag when the drug chamber is pressed. It spreads, and the breakable part is opened on one sheet side to break.
The joining of the flat part of the first stress applying part 34 and the flat part of the second stress applying part 35 to the inner surface of each sheet of the flexible bag 2 is performed by ultrasonic fusion, high frequency fusion, thermal fusion or the like. Are preferred. Specifically, after the discharge port 3 is arranged at a position as shown in FIG. 1, the sheet is sandwiched from both sides of one sheet and the other sheet surface of the flexible bag 2 by a sealing mold and heat sealed. It is preferable.

The first stress applying part and the second stress applying part in the discharge port 3 are not limited to those having the above-described configuration, and can be joined to one sheet inner surface and the other sheet inner surface constituting the soft bag. In addition, any configuration may be used as long as it has a configuration capable of applying stress to the breakable portion in conjunction with the swelling of the soft bag. For example, it may not be formed to extend in the axial direction of the medicine container, but may be formed obliquely with respect to the medicine container.
Furthermore, in the discharge port 3 of this embodiment, the needle tube entry inhibiting member 4 is accommodated in the discharge port 3 of the medical container hollow body 30. As shown in FIG. 3, the needle tube intrusion inhibiting member 4 in this embodiment includes a main body portion 41 having a tip portion that can come into contact with the inside of the tip portion of the cylindrical portion 32 of the medical container hollow body 30, and a medical needle tube. A proximal end portion 43 with which the distal end can be brought into contact, and a connecting portion 42 for connecting the distal end portion 41 and the proximal end portion 43.
When the sealable member 52 is punctured with the medical needle tube when the breakable portion 36 of the medical container hollow body 30 is not broken (the state shown in FIG. 3), the tip of the needle is the needle tube intrusion inhibiting member 4. Abuts against the base end portion 43 to prevent entry. The operator recognizes that the breakable portion 36 of the medical container hollow body 30 is unbroken because the medical needle tube is not puncturable.
The length of puncture to the discharge port of the medical needle tube when the breakable portion 36 of the medical container hollow body 30 is not broken (state shown in FIG. 3) is such that the opening of the medical needle tube is inside the discharge port. It is preferable that the length does not allow communication.

In the needle tube entry inhibiting member 4 of this example, the main body portion 41 has a cross-shaped cross section having plate-like portions 41a, 41b, 41c, 41d extending in the four axial directions as shown in FIGS. ing. Moreover, the base end part 43 is formed in a disk shape as shown in FIGS. Further, the connecting portion 42 that connects the main body portion 41 and the base end portion 43 is formed by four flat plate portions 42a, 42b, 42c, and 42d that extend in the outer edge direction from the center of the upper surface of the disk-like base end portion and protrude from the outer edge. The upper portions of the flat plate portions 42a, 42b, 42c, and 42d are connected to the lower portions of the corresponding plate-like portions 41a, 41b, 41c, and 41d.
The needle tube entry inhibiting member 4 can flow out of the discharge port after the breakable portion 36 of the medical container hollow body 30 is broken. However, the present invention is not limited to this, and the needle tube entry inhibiting member may remain in the discharge port after the breakable portion is broken. The needle tube entry inhibiting member 4 may be any needle tube entry inhibiting member as long as it restricts puncture of the discharge port of the medical needle tube in the unbreakable state of the breakable portion 36 of the medical container hollow body 30. It is not limited to members.

In the medical container 1 of this embodiment, when the medicine chamber 11 is inflated by pressing the medicine chamber 11 of the medical container 1, this swelling (opening of the first fixing portion 21 and the second fixing portion 22) is performed. In conjunction with FIG. 16, as shown in FIG. 16, the first stress applying part 34 and the second stress applying part 35 of the medical container hollow body 30 open in the direction of the one sheet 2a and the other sheet 2b, First, the tip side portion of the breakable portion 36 is broken, and then the first stress applying portion side portion is broken. As a result, the hollow body 31 is opened, the plastically deformable portion 37 is deformed (curved), the cylindrical portion 32 communicates with the drug chamber 11, and the needle tube entry inhibiting member 4 is formed as shown in FIG. The medicine flows out from the port body and can be connected to the needle tube, and the medicine in the discharge port is mixed with the medicine in the medicine chamber 11 of the soft bag 2. Moreover, since the plastically deformable portion 37 maintains a deformed state, the cylindrical portion of the medical container hollow body 30 is not blocked by the first stress applying portion.
Moreover, in the discharge port 3 of this embodiment, as shown in FIGS. 2 and 3, a cylindrical attachment member 55 for attaching the discharge port 3 (medical container hollow body 30) to the soft bag 2 is provided. . The cylindrical mounting member 55 is a cylindrical body that encloses an intermediate portion of the cylindrical part 32 of the medical container hollow body 30, and as shown in FIG. 14, the cylindrical part of the medical container hollow body 30. This is a cylindrical body having a main body portion 56 fitted to the main body 32 and an enlarged diameter portion 57 for accommodating the flange portion 33 of the cylindrical portion 32. In addition, as a discharge port, you may not provide the cylindrical attachment member 55. FIG.
Moreover, as a discharge port and the hollow body for medical containers, it may be as shown in FIG. The basic configurations of the discharge port 3a and the medical container hollow body 30a in this embodiment are the same as those of the discharge port 3 and the medical container hollow body 30 described above.

In the medical container hollow body 30a used in this embodiment, as shown in FIG. 17, the breakable portion 36 is provided so as to pass between the first stress applying portion 34 and the second stress applying portion 35. The distal end portion thus formed, and a first stress applying portion side portion 36a and a second stress applying side portion 36b branched from the distal end side portion and extending in the side surface direction of the cylindrical portion 32 are provided. The breakable portion is formed so as to surround the base end portions of the first stress applying portion 34 and the second stress applying portion 35. The first stress applying portion side portion 36a of the breakable portion includes a partially breakable portion missing portion at the base end portion. A plastically deformable portion 37a is formed by the missing portion. Similarly, the second stress applying portion side portion 36b of the breakable portion includes a partially breakable portion missing portion at the base end portion. A plastically deformable portion 37b is formed by the missing portion. Specifically, in this embodiment, the breakable portion is the distal end portion of the cylindrical portion 32, and the proximal end portion and the cylindrical portion of the first stress applying portion 34 and the second stress applying portion 35. And having a starting end and a terminal end, it is formed in a substantially annular shape. The plastically deformable portions 37a and 37b are formed between the start end and the end of the breakable portion. The plastically deformable portions 37a and 37b are plastically deformed but do not break in the widening operation (breaking operation of the breakable portion 36) between the first stress applying portion 34 and the second stress applying portion 35. . Therefore, the first stress applying part 34 and the second stress applying part 35 are hollow in the widening operation (breaking operation of the breakable part 36) between the first stress applying part 34 and the second stress applying part 35. It is not separated from the body 30a. The width of the plastically deformable portions 37a and 37b, in other words, the distance between the start end and the end of the breakable portion is preferably about 4 to 9 mm, and particularly preferably 6 to 8 mm.
As shown in FIGS. 18 and 19, when the drug chamber 11 is pressed, the vicinity of the fixing portion of the first stress applying portion 34 and the second stress applying portion 35 to the soft bag 2 swells and the first stress is applied. By applying a force in the opening direction to the part 34 and the second stress applying part 35, the breakable part is broken, and subsequently, the plastically deformable part is plastically deformed. In particular, in the medical container using the discharge port (hollow body for medical container) of this embodiment, even if either side is placed on the operation table and the drug chamber is pressed from above, the placement state The breakable part which became the surface side of this breaks, the plastic deformation part deforms, and the workability is improved.

Further, the medical container of the present invention may be as shown in FIG.
The difference between the medical container 20 of this embodiment and the medical container 1 described above is that the soft bag 2 has a different form and has a mixed injection port.
The medical container 20 includes a soft bag 2, a discharge port 3 and a mixed injection port 8 attached to the soft bag 2. As the discharge port 3, those described above are preferably used.
As illustrated in FIG. 20, the medical container 20 includes a soft bag 2, a chemical solution, a discharge port 3, and a mixed injection port 8.
As shown in FIG. 20, the soft bag 2 is divided into a first drug chamber (chemical solution chamber) 11 and a second drug chamber (chemical solution chamber) 12 by a partitionable weak seal portion 9 for separation.
Moreover, in the soft bag 2, as shown in FIG. 20, between the sheet | seats provided in the vicinity of the chemical | medical chamber side front-end | tip part of the discharge port 3, and were fixed by the 1st stress application part and the 2nd stress application part. A peelable spread suppressing sheet fixing portion 25 for suppressing spread is provided. In addition, the peelable spread suppressing inter-sheet fixing portion for suppressing the spread between sheets fixed to the medical container 1 of the above-described embodiment by the first stress applying portion and the second stress applying portion. May be provided.
In the embodiment shown in FIG. 20, the inter-sheet fixing portion 25 for suppressing spread is formed so as to surround the vicinity of the distal end portions of the first stress applying portion and the second stress applying portion of the discharge port 3. It is preferable that the inter-sheet fixing portion for suppressing the spread is not peeled off by pressure applied to the soft bag 2 before use such as during transportation, but is peelable when the soft bag 2 is strongly pressed with a finger. The inter-sheet fixing portion 25 is preferably in an arc shape that is continuous with the position near the tip of the stress applying portion and inside the drug chamber, as in the illustrated embodiment. Note that the inter-sheet fixing portion 25 may be a plurality of dot-like ones instead of being continuous. Furthermore, the inter-sheet fixing part 25 may be provided in such a manner that one or two stress applying parts 34 and 35 are sandwiched between the vicinity of the tip of the stress applying part and on the side surface thereof. As shown in FIG. 20, the spread suppressing sheet fixing portion 25 does not form a chamber partitioned from the drug chamber 11 because both end portions do not reach the seal portion 6.

The inter-sheet fixing part 25 is preferably formed by fusing the soft bag 2 so as to be peelable. The fusion is preferably thermal fusion, high frequency fusion or the like. The inter-sheet fixing part 25 is preferably performed by a hot press, and the mold temperature can be formed by performing the process at a temperature lower by 10 ° C. or more than the melting temperature of the forming material of the soft bag 2. By including the inter-sheet fixing portion for suppressing the spread, there is no possibility that the soft bag 2 swells during transportation and the first stress applying portion and the second stress applying portion are cleaved. In addition, as a shape of the fixing part between sheet | seats for expansion suppression, what kind of thing may be sufficient as long as it can prevent that a cylindrical part is fractured | ruptured before use, such as during transportation.
As shown in FIG. 20, the soft bag 2 is partitioned into a first drug chamber 11 and a second drug chamber 12 by a partition weak seal portion 9 that can be peeled off. As shown in FIG. 20, the partition weak seal portion 9 is provided so as to cross the entire lateral direction of the drug chamber of the soft bag 2. The partition weak seal portion 9 is formed by fusing the sheet material of the soft bag 2 in a band shape. In the embodiment of the present invention, strong seal portions 9 a that do not substantially peel off are formed at both ends of the partition weak seal portion 9. The partition weak seal portion 9 of the embodiment peels off when the second drug chamber 12 is strongly pressed with a finger or the like (when squeezed or gripped), and is separated from the first drug chamber 11 and the second drug chamber. 12 can be communicated.
The peeling strength of the partition weak seal portion 9 is preferably such that it does not peel off by the pressure applied to the soft bag 2 during transportation but peels when the soft bag 2 is strongly pressed with a finger or the like. The partition weak seal portion 9 is preferably formed by fusing the soft bag 2. The fusion is preferably thermal fusion, high frequency fusion or the like. Since the soft bag 2 has the two drug chambers 11 and 12 partitioned by the partition weak seal portion 9 in this way, drugs of different components can be mixed aseptically in the soft bag 2. it can. In the embodiment shown in FIG. 20, the partition weak seal portion 9 is formed in a strip shape horizontally with respect to the soft bag 2, but is not limited thereto.

In the drug chambers 11 and 12 of the soft bag 2, infusion agents (chemical solutions) are respectively stored. As such an infusion, for example, two or more liquids such as peritoneal dialysis solution, transcentral vein infusion, transperipheral vein infusion, transperipheral vein injection, liquid nutrient, etc. Those that need to be mixed are preferred. Examples of the infusion include physiological saline, electrolyte solution, Ringer's solution, high calorie infusion, glucose solution, water for injection, amino acid electrolyte solution, and the like, but are not limited thereto. For example, a glucose electrolyte solution is stored in one of the drug rooms, an amino acid solution is stored in the other, and water-soluble vitamins such as vitamin B1, vitamin B2, vitamin B6, vitamin C, panthenol, and nicotinamide are stabilized in both chambers. Can be appropriately sorted and stored. In this case, a vitamin-containing high-calorie total infusion solution can be obtained by storing a liquid preparation mainly composed of fat-soluble vitamins such as vitamin A, vitamin D, vitamin E, and vitamin K in a drug container attached to a drug room described later. .
A mixed injection port 8 is attached to the upper end side seal portion 5. A well-known port can be used as the mixed injection port.

Although the medical container 20 of the embodiment described above includes the inter-sheet fixing portion 25 for suppressing expansion as described above, the present invention is not limited to this, and the medical container 20a of the embodiment shown in FIG. As described above, it may be one that does not have the inter-sheet fixing portion 25 for suppressing expansion.
Moreover, the soft bag 2 may be provided with the weak seal part 26 for communication inhibition formed so that the upper part of the discharge port 3 may be surrounded like the medical container 20b shown in FIG. A small chamber 27 isolated from the first drug chamber 11 is formed by the weak seal portion 26 for inhibiting communication. This small room 27 is an empty room in the embodiment of the present invention. However, the small chamber 27 may contain a predetermined liquid (for example, physiological saline). The small chamber 27 may be in a dry state, but may be filled with a small amount of liquid for sterilization. Further, a passage through which some water vapor or medicine passes through the communication inhibiting weak seal portion 26 may be formed so as to communicate with the small chamber 27 at the above-described level. The weak seal portion 26 for inhibiting communication can be formed by heat-sealing a sheet material in a band shape (thermal fusion, high frequency fusion, ultrasonic fusion, etc.). In the embodiment shown in FIG. 25, the communication inhibiting weak seal portion 26 is formed in an inverted U-shape. Further, the weak seal portion 26 for inhibiting communication has a trapezoidal shape with the short side on the upper side, a triangular shape with the discharge port at the top, a triangular shape with the discharge port at the bottom, a polygonal shape such as a quadrangle, a substantially semicircular shape, A substantially semi-elliptical shape may be used.

Next, an embodiment in which a medical container hollow body is applied to a drug container will be described.
As shown in FIGS. 21 and 22, the drug container 7 of this embodiment is filled in the hollow body 70 for medical use, the sealing member 72 that seals the opening of the hollow body 70, and the hollow body 70. The medicine 73 is made.
The medical container hollow body 70 sandwiches the tubular portion 71 with the closed end portion, the breakable portion 76 provided at the distal end portion of the tubular portion 71, and the breakable portion 76 of the tubular portion 71. A first stress applying portion 74 that is provided and can be fixed to the inner surface of one sheet 2a of the soft bag 2 and a second stress applying portion 75 that can be fixed to the inner surface of the other sheet 2b of the soft bag 2 are provided. . The breakable portion 76 breaks due to the spread between the first stress applying portion 74 and the second stress applying portion 75 and opens the cylindrical portion 71. Furthermore, the breakable part 76 has a start end and a terminal end at the base end part of the first stress applying part 74 or the second stress applying part 75, and is formed between the start end and the terminal end of the breakable part 76, A state in which the space between the first stress applying portion 74 and the second stress applying portion 75 expands, plastically deforms after the breakable portion 76 breaks, and the space between the first stress applying portion 74 and the second stress applying portion 75 expands. A plastically deformable portion (in other words, a deformable state maintainable portion, a plastically deformable state maintainable portion) 77 is provided.
And the 1st stress provision part 74 and the 2nd stress provision part 75 are the same structures as the 1st stress provision part 34 and the 2nd stress provision part 35 which were demonstrated in the hollow body 30 for medical containers mentioned above. It is preferable that In addition, the breakable portion 76 and the plastically deformable portion 77 preferably have the same configurations as the breakable portion 36 and the plastically deformable portion 37 described in the medical container hollow body 30 described above.

The medical container of the present invention may be as shown in FIG.
The medical container 60 of this embodiment includes a soft bag 2, a drug chamber 11 formed in the soft bag 2, a drug solution filled in the drug chamber 11, and a drug solution in the drug chamber 11 attached to the soft bag 2. And a medicine container 7 in which medicine for mixing is stored, and a discharge port 3 attached to the soft bag 2. As the medicine container 7, the above medicine container 7 using the medical container hollow body 70 of the present invention is used.
A part of the flat plate portion 74a of the first stress applying portion 74 of the medical container hollow body 70 is fixed to the inner surface of one sheet 2a forming the drug chamber 11 of the soft bag 2, and the second A part of the flat plate portion 75 a of the stress applying portion 75 is fixed to the inner surface of the other sheet 2 b forming the drug chamber 11 of the soft bag 2, and the breakable portion 76 is the soft bag 2 when the drug chamber 11 is pressed. The first stress applying portion 74 and the second stress applying portion 75 that are fixed to each other are broken and the inside of the medicine container 7 is communicated with the medicine chamber 11.
Also in the drug container 7 of this embodiment, the medical container hollow body 70 is similar to the one shown in FIG. 6 in that the breakable portion 76 includes the first stress applying portion 74 and the second stress applying portion. It has a tip side part provided so as to pass between the part 75 and a first stress applying part side part extending in the side surface direction of the cylindrical part 71 from the tip side part. When the medicine chamber 12 is pressed, the vicinity of the fixing portion of the first stress applying portion 74 to the soft bag 2 swells, and the first stress applying portion 74 is pulled, whereby the first stress applying portion 74 is By applying a force that opens in a direction away from the second stress applying portion 75, the breakable portion 76 is broken, and subsequently, the plastically deformable portion 77 is plastically deformed. Since the plastically deformable portion 77 maintains a state where the first stress applying portion 74 and the second stress applying portion 75 are expanded (plastic deformation state), the cylindrical portion 71 of the medical container hollow body 70 is It is not blocked by the first stress applying part.

Similarly to the medical container 20 described above, the medical container 60 of this embodiment is also provided in the soft bag 2 near the tip of the drug chamber side of the drug container 7, as shown in FIG. A peelable spread suppressing inter-sheet fixing portion 78 for suppressing the spread between sheets fixed by the first stress applying portion and the second stress applying portion is provided. As the expansion suppression sheet fixing portion 78, the same one as the expansion suppression sheet fixing portion 25 described above is suitable. Further, the medical container 60 of this embodiment is also provided in the first drug chamber 11 and the second drug chamber 12 from the soft seal 2 to the soft bag 2 and from the detachable partitioning weak seal portion 9 in the same manner as the medical container 20 described above. It is partitioned. The partition weak seal portion 9 is preferably the same as described above.
Moreover, in the medical container 60 of this Example, as shown in FIG. 23, the lower end side seal part 6 of the soft bag 2 has the discharge port 10. As the discharge port 10, it is preferable to use a known one as shown in FIG. 23, and for example, it is preferable to include a cylindrical port member and a seal member that seals the opening and can be inserted through the needle tube.
Furthermore, in the medical container 60 of this embodiment, as shown in FIG. 23, the soft bag 2 includes a communication inhibiting weak seal portion 26 that inhibits communication between the discharge port 10 and the first drug chamber 11. Yes.
The communication-inhibiting weak seal portion 26 is formed so as to surround the upper portion of the discharge port 10. A small chamber 27 isolated from the first drug chamber 11 is formed by the weak seal portion 26 for inhibiting communication. This small room 27 is an empty room in the embodiment of the present invention. However, the small chamber 27 may contain a predetermined liquid (for example, physiological saline). The small chamber 27 may be in a dry state, but may be filled with a small amount of liquid for sterilization. Further, a passage through which some water vapor or medicine passes through the communication inhibiting weak seal portion 26 may be formed so as to communicate with the small chamber 27 at the above-described level. The weak seal portion 26 for inhibiting communication can be formed by heat-sealing a sheet material in a band shape (thermal fusion, high frequency fusion, ultrasonic fusion, etc.).
In the embodiment shown in FIG. 23, the weak seal portion 26 for inhibiting communication is formed in an inverted U shape. Further, the weak seal portion 26 for inhibiting communication has a trapezoidal shape with the short side on the upper side, a triangular shape with the discharge port at the top, a triangular shape with the discharge port at the bottom, a polygonal shape such as a quadrangle, a substantially semicircular shape, A substantially semi-elliptical shape may be used.

1, 20, 60 Medical container 2 Soft bag 3 Discharge port 7 Drug container 30 Medical container hollow body 34 First stress applying part 35 Second stress applying part 36 Breakable part 37 Plastic deformable part

Claims (7)

A medical container comprising a soft bag, a drug solution chamber formed in the soft bag, a drug solution filled in the drug solution chamber, and a discharge port attached to the soft bag,
The discharge port is formed of a hard or semi-rigid material, the front end portion is closed, the rear end portion is opened, the rear end portion of the hollow body is sealed, and a medical needle tube can be connected A sealing part,
  The hollow body is provided so as to sandwich the tubular portion with the closed end portion, the breakable portion provided in the tubular portion, and the breakable portion of the tubular portion, and one of the flexible bags A first stress applying portion that can be fixed to the inner surface of the sheet and a second stress applying portion that can be fixed to the inner surface of the other sheet of the flexible bag, wherein the breakable portion is the first stress applying portion. And the second stress applying part are opened by opening the cylindrical part, and the first stress applying part and the second stress applying part are the breakable parts. Is not separated from the hollow body after breaking,
  The breakable portion has a start end and a terminal end at a proximal end portion of the first stress applying portion or the second stress applying portion, and the breakable portion is provided at a distal end portion of the cylindrical portion. And a front end side portion provided so as to pass between the first stress applying portion and the second stress applying portion, and a side surface direction and a rear end direction of the tubular portion from the front end side portion. Having a stress applying part side portion extending obliquely to
  Further, the hollow body is formed between the start end and the end of the breakable portion, and the space between the first stress applying portion and the second stress applying portion expands, and plastic deformation occurs after the breakable portion is broken. And a plastically deformable portion that maintains a state in which the space between the first stress applying portion and the second stress applying portion is expanded, and the distal end portion of the outer surface of the first stress applying portion is the soft Fixed to the inner surface of one sheet forming the chemical chamber of the bag, and the tip of the outer surface of the second stress applying section is fixed to the inner surface of the other sheet forming the chemical chamber of the soft bag The breakable portion is broken by the spread of the first stress applying portion and the second stress applying portion fixed to the soft bag when the chemical chamber is pressed, and the inside of the discharge port It is intended to communicate with the chemical chamber. Medical container and said. The medical container according to claim 1, wherein a medicine is accommodated in the cylindrical portion of the medical container discharge port. Stored in the hollow body of the medical container discharge port are a drug and a needle tube entry inhibiting member that inhibits the medical needle tube from entering the hollow body when the breakable portion is not broken. The medical container according to claim 1. A soft bag, a drug solution chamber formed in the soft bag, a drug solution filled in the drug solution chamber, a drug container attached to the soft bag and containing a drug for mixing with the drug solution, and the soft bag A medical container comprising a discharge port attached to the bag,
  The drug container is formed of a hard or semi-rigid material, and has a hollow body having one end opened, a sealing member that seals the one end of the hollow body, and a drug stored in the hollow body. ,
  The hollow body is provided so as to sandwich the tubular portion with the closed end portion, the breakable portion provided in the tubular portion, and the breakable portion of the tubular portion, and one of the flexible bags A first stress applying portion that can be fixed to the inner surface of the sheet and a second stress applying portion that can be fixed to the inner surface of the other sheet of the flexible bag, wherein the breakable portion is the first stress applying portion. And the second stress applying part are opened by opening the cylindrical part, and the first stress applying part and the second stress applying part are the breakable parts. Is not separated from the hollow body after breaking,
  The breakable portion has a start end and a terminal end at a proximal end portion of the first stress applying portion or the second stress applying portion, and the breakable portion is provided at a distal end portion of the cylindrical portion. And a front end side portion provided so as to pass between the first stress applying portion and the second stress applying portion, and a side surface direction and a rear end direction of the tubular portion from the front end side portion. Having a stress applying part side portion extending obliquely to
  Further, the hollow body is formed between the start end and the end of the breakable portion, and the space between the first stress applying portion and the second stress applying portion expands, and plastic deformation occurs after the breakable portion is broken. And a plastically deformable portion that maintains a state in which the space between the first stress applying portion and the second stress applying portion is expanded, and the distal end portion of the outer surface of the first stress applying portion is the soft Fixed to the inner surface of one sheet forming the chemical chamber of the bag, and the tip of the outer surface of the second stress applying section is fixed to the inner surface of the other sheet forming the chemical chamber of the soft bag The breakable portion is broken by the spread of the first stress applying portion and the second stress applying portion fixed to the soft bag when the drug solution chamber is pressed, and the inside of the drug container is It should be in communication with the chemical chamber Medical container and said. The breakable portion is formed so as to surround a proximal end portion of the first stress applying portion or the second stress applying portion, and the first stress applying portion or the second stress applying portion. comprising a partially breakable portion defects at the proximal end of the section, by the defect, the with plastically deformable portion is formed, the composition deformable portion, the said composition deformable portion is provided The medical container according to any one of claims 1 to 4, wherein the first stress applying part or the second stress applying part is not allowed to be separated from the hollow body. The medical container according to any one of claims 1 to 5, wherein the breakable portion is provided only in one of the first stress applying portion and the second stress applying portion. The first stress applying part and the second stress applying part include a flat part for fixing to the inner surface of the soft bag, and the plastically deformable part is the hollow body for a medical container of the flat part. The medical container according to any one of claims 1 to 6 , wherein the medical container is formed so as to be located on an extension line in the axial direction.

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