JP5624766B2 - アルコールを含まないアルガトロバン製剤 - Google Patents

アルコールを含まないアルガトロバン製剤 Download PDF

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Publication number
JP5624766B2
JP5624766B2 JP2009530403A JP2009530403A JP5624766B2 JP 5624766 B2 JP5624766 B2 JP 5624766B2 JP 2009530403 A JP2009530403 A JP 2009530403A JP 2009530403 A JP2009530403 A JP 2009530403A JP 5624766 B2 JP5624766 B2 JP 5624766B2
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JP
Japan
Prior art keywords
salt
argatroban
formulation
pharmaceutically acceptable
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2009530403A
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English (en)
Japanese (ja)
Other versions
JP2010504971A5 (enExample
JP2010504971A (ja
Inventor
ナゲスワラ・アール・パレプ
Original Assignee
イーグル・ファーマシューティカルズ・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39230808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5624766(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by イーグル・ファーマシューティカルズ・インコーポレーテッド filed Critical イーグル・ファーマシューティカルズ・インコーポレーテッド
Publication of JP2010504971A publication Critical patent/JP2010504971A/ja
Publication of JP2010504971A5 publication Critical patent/JP2010504971A5/ja
Application granted granted Critical
Publication of JP5624766B2 publication Critical patent/JP5624766B2/ja
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009530403A 2006-09-27 2007-09-26 アルコールを含まないアルガトロバン製剤 Active JP5624766B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84755606P 2006-09-27 2006-09-27
US60/847,556 2006-09-27
US85072506P 2006-10-11 2006-10-11
US60/850,725 2006-10-11
PCT/US2007/020725 WO2008039473A2 (en) 2006-09-27 2007-09-26 Alcohol free formulation of argatroban

Publications (3)

Publication Number Publication Date
JP2010504971A JP2010504971A (ja) 2010-02-18
JP2010504971A5 JP2010504971A5 (enExample) 2013-04-18
JP5624766B2 true JP5624766B2 (ja) 2014-11-12

Family

ID=39230808

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009530403A Active JP5624766B2 (ja) 2006-09-27 2007-09-26 アルコールを含まないアルガトロバン製剤

Country Status (5)

Country Link
US (1) US7589106B2 (enExample)
EP (1) EP2083823A4 (enExample)
JP (1) JP5624766B2 (enExample)
CA (1) CA2669727C (enExample)
WO (1) WO2008039473A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7915290B2 (en) * 2008-02-29 2011-03-29 Baxter International Inc. Argatroban formulations and methods for making and using same
WO2012054831A2 (en) 2010-10-21 2012-04-26 Rtu Pharmaceuticals, Llc Ready to use ketorolac formulations
EP2884963B1 (en) * 2012-08-15 2017-12-27 Yung Shin Pharm. Ind. Co. Ltd. Stable pharmaceutical formulation of cabazitaxel
US9636376B2 (en) 2012-09-11 2017-05-02 Innopharma, Inc. Stable compositions of peptide epoxy ketones

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5214052A (en) 1987-07-28 1993-05-25 Mitsubishi Kasei Corporation Method for dissolving arginineamides and pharmaceutical compositions containing them
US5506241A (en) 1992-03-18 1996-04-09 Mitsubishi Chemical Corporation Argatroban preparations for ophthalmic use
JPH06219949A (ja) 1993-01-25 1994-08-09 Mitsubishi Kasei Corp 抗トロンビン剤及びその製造方法
JPH06219948A (ja) 1993-01-25 1994-08-09 Mitsubishi Kasei Corp 抗トロンビン剤及びその製造方法
JPH07228532A (ja) * 1993-04-22 1995-08-29 Senju Pharmaceut Co Ltd 水性液剤、その有効成分の溶解性向上方法および安定化方法
EP0621036B1 (en) 1993-04-22 1999-03-17 Senju Pharmaceutical Co., Ltd. Aqueous compositions comprising argatroban and cyclodextrin or caffeine
FR2715566B1 (fr) * 1994-02-03 1996-03-08 Synthelabo Solutions aqueuses concentrées d'argatroban.
EP1117398A2 (en) 1998-09-28 2001-07-25 Merck & Co., Inc. A method for treating inflammatory diseases by administering a thrombin inhibitor
US6495534B2 (en) * 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
ATE427948T1 (de) 2001-04-24 2009-04-15 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
WO2004026252A2 (en) 2002-09-23 2004-04-01 The Regents Of The University Of Michigan Glioma treatments
ATE514416T1 (de) 2005-09-01 2011-07-15 Baxter Internat Inc A Delaware Corp Argatrobanformulierung mit einer säure als lösungsvermittler

Also Published As

Publication number Publication date
CA2669727C (en) 2014-10-28
WO2008039473A2 (en) 2008-04-03
US20080076798A1 (en) 2008-03-27
EP2083823A2 (en) 2009-08-05
JP2010504971A (ja) 2010-02-18
US7589106B2 (en) 2009-09-15
CA2669727A1 (en) 2008-04-03
EP2083823A4 (en) 2010-01-13
WO2008039473A3 (en) 2008-06-12

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