JP5596563B2 - 特異的且つ選択的な電場および電磁場の印加を使用した生体細胞における線維芽成長因子−２（ｆｇｆ−２）遺伝子発現の制御 - Google Patents

特異的且つ選択的な電場および電磁場の印加を使用した生体細胞における線維芽成長因子−２（ｆｇｆ−２）遺伝子発現の制御 Download PDF

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JP5596563B2
JP5596563B2 JP2010545946A JP2010545946A JP5596563B2 JP 5596563 B2 JP5596563 B2 JP 5596563B2 JP 2010545946 A JP2010545946 A JP 2010545946A JP 2010545946 A JP2010545946 A JP 2010545946A JP 5596563 B2 JP5596563 B2 JP 5596563B2
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ブライトン、カール、ティー．
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2010545946A 2008-02-08 2009-02-03 特異的且つ選択的な電場および電磁場の印加を使用した生体細胞における線維芽成長因子−２（ｆｇｆ−２）遺伝子発現の制御 Active JP5596563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/028,530 US7981611B2 (en) 2000-02-23 2008-02-08 Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
US12/028,530 2008-02-08
PCT/US2009/032925 WO2009100048A1 (en) 2008-02-08 2009-02-03 Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric an electromagnetic fields

Publications (3)

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JP2011514813A JP2011514813A (ja) 2011-05-12
JP2011514813A5 JP2011514813A5 (enExample) 2012-03-22
JP5596563B2 true JP5596563B2 (ja) 2014-09-24

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JP2010545946A Active JP5596563B2 (ja) 2008-02-08 2009-02-03 特異的且つ選択的な電場および電磁場の印加を使用した生体細胞における線維芽成長因子−２（ｆｇｆ−２）遺伝子発現の制御

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Country Link
US (1) US7981611B2 (enExample)
EP (1) EP2250250A4 (enExample)
JP (1) JP5596563B2 (enExample)
CN (1) CN101939409A (enExample)
AU (1) AU2009212561B2 (enExample)
CA (1) CA2712991A1 (enExample)
IL (1) IL207430A0 (enExample)
MX (1) MX2010008765A (enExample)
RU (1) RU2010137343A (enExample)
WO (1) WO2009100048A1 (enExample)
ZA (1) ZA201006311B (enExample)

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US8313908B2 (en) * 2000-02-23 2012-11-20 The Trustees Of The University Of Pennsylvania Regulation of stem cell gene production with specific and selective electric and electromagnetic fields
US10188858B2 (en) 2013-09-18 2019-01-29 University Of Cincinnati Method and device for treating a tissue with a high frequency electromagnetic field
WO2017118390A1 (zh) * 2016-01-05 2017-07-13 吴翔 利用变化电场磁场电磁场有选择地操控分子
US10806942B2 (en) 2016-11-10 2020-10-20 Qoravita LLC System and method for applying a low frequency magnetic field to biological tissues
US20240033509A1 (en) * 2022-08-01 2024-02-01 BonGenix, LLC Method and device for stimulating bone growth

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US7981611B2 (en) 2011-07-19
EP2250250A1 (en) 2010-11-17
MX2010008765A (es) 2010-09-30
AU2009212561A1 (en) 2009-08-13
ZA201006311B (en) 2011-07-27
CA2712991A1 (en) 2009-08-13
RU2010137343A (ru) 2012-03-20
AU2009212561B2 (en) 2015-01-29
CN101939409A (zh) 2011-01-05
EP2250250A4 (en) 2011-08-24
WO2009100048A1 (en) 2009-08-13
US20080215116A1 (en) 2008-09-04
IL207430A0 (en) 2010-12-30
JP2011514813A (ja) 2011-05-12

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