MX2010008765A - Regulacion de expresion de genes de factor de crecimiento de fibroblastos-2 (fgf-2) en celulas vivas con la aplicacion de campos electricos y electromagnetivos especificos y selectivos. - Google Patents

Regulacion de expresion de genes de factor de crecimiento de fibroblastos-2 (fgf-2) en celulas vivas con la aplicacion de campos electricos y electromagnetivos especificos y selectivos.

Info

Publication number
MX2010008765A
MX2010008765A MX2010008765A MX2010008765A MX2010008765A MX 2010008765 A MX2010008765 A MX 2010008765A MX 2010008765 A MX2010008765 A MX 2010008765A MX 2010008765 A MX2010008765 A MX 2010008765A MX 2010008765 A MX2010008765 A MX 2010008765A
Authority
MX
Mexico
Prior art keywords
specific
bone
fgf
regulation
gene expression
Prior art date
Application number
MX2010008765A
Other languages
English (en)
Spanish (es)
Inventor
Carl T Brighton
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of MX2010008765A publication Critical patent/MX2010008765A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2010008765A 2008-02-08 2009-02-03 Regulacion de expresion de genes de factor de crecimiento de fibroblastos-2 (fgf-2) en celulas vivas con la aplicacion de campos electricos y electromagnetivos especificos y selectivos. MX2010008765A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/028,530 US7981611B2 (en) 2000-02-23 2008-02-08 Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
PCT/US2009/032925 WO2009100048A1 (en) 2008-02-08 2009-02-03 Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric an electromagnetic fields

Publications (1)

Publication Number Publication Date
MX2010008765A true MX2010008765A (es) 2010-09-30

Family

ID=40952436

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010008765A MX2010008765A (es) 2008-02-08 2009-02-03 Regulacion de expresion de genes de factor de crecimiento de fibroblastos-2 (fgf-2) en celulas vivas con la aplicacion de campos electricos y electromagnetivos especificos y selectivos.

Country Status (11)

Country Link
US (1) US7981611B2 (enExample)
EP (1) EP2250250A4 (enExample)
JP (1) JP5596563B2 (enExample)
CN (1) CN101939409A (enExample)
AU (1) AU2009212561B2 (enExample)
CA (1) CA2712991A1 (enExample)
IL (1) IL207430A0 (enExample)
MX (1) MX2010008765A (enExample)
RU (1) RU2010137343A (enExample)
WO (1) WO2009100048A1 (enExample)
ZA (1) ZA201006311B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313908B2 (en) * 2000-02-23 2012-11-20 The Trustees Of The University Of Pennsylvania Regulation of stem cell gene production with specific and selective electric and electromagnetic fields
US10188858B2 (en) 2013-09-18 2019-01-29 University Of Cincinnati Method and device for treating a tissue with a high frequency electromagnetic field
WO2017118390A1 (zh) * 2016-01-05 2017-07-13 吴翔 利用变化电场磁场电磁场有选择地操控分子
US10806942B2 (en) 2016-11-10 2020-10-20 Qoravita LLC System and method for applying a low frequency magnetic field to biological tissues
US20240033509A1 (en) * 2022-08-01 2024-02-01 BonGenix, LLC Method and device for stimulating bone growth

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430999A (en) * 1981-11-10 1984-02-14 Trustees Of The University Of Pennsylvania Osteogenesis stimulating cathode assembly for use with an internal fixation device
US4506674A (en) * 1981-11-10 1985-03-26 Trustees Of The University Of Pennsylvania Method of stimulating osteogenesis with distributed port cathode
US4442846A (en) * 1981-11-10 1984-04-17 University Of Pennsylvania Distributed port bone-piercing cathode for electrically stimulated osteogenesis
US4509520A (en) * 1982-02-22 1985-04-09 Biolectron, Inc. Electrical stimulating apparatus
US4549547A (en) * 1982-07-27 1985-10-29 Trustees Of The University Of Pennsylvania Implantable bone growth stimulator
US4467809A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4467808A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for preventing and treating osteoporosis in a living body by using electrical stimulation non-invasively
US4487834A (en) * 1982-09-17 1984-12-11 Biolectron, Inc. Electrical stimulation of articular chondrocytes
US5269746A (en) * 1982-12-20 1993-12-14 Jacobson Jerry I Therapeutic treatment of mammals for epilepsy and Parkinson's disease
US4535775A (en) * 1983-02-10 1985-08-20 Biolectron, Inc. Method for treatment of non-union bone fractures by non-invasive electrical stimulation
IT1159024B (it) * 1983-06-02 1987-02-25 Ruggero Cadossi Metodo e dispositivo per il trattamento di tessuti e cellule viventi mediante campi elettromagnetici pulsanti
US4600010A (en) * 1984-10-04 1986-07-15 Biolectron, Inc. Electric stimulator and test instrument therefor
US4998532A (en) * 1986-05-23 1991-03-12 Lti Biomedical, Inc. Portable electro-therapy system
US5014699A (en) * 1986-05-23 1991-05-14 Trustees Of The University Of Pennsylvania Electromagnetic method and apparatus for healing living tissue
US6120502A (en) * 1988-06-13 2000-09-19 Michelson; Gary Karlin Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis
US5038797A (en) * 1990-02-20 1991-08-13 Romaine, Incorporated Electrical stimulation treatment device and method of use
US5273033A (en) 1991-09-19 1993-12-28 Murray Electronics Associates Limited Partnership Electrical stimulation for treatment of osteoarthritis
US5338286A (en) * 1992-12-08 1994-08-16 Electro-Biology, Inc. Electromagnetic bioresponse by selective spectral suppression in pulsed field stimulation
US5374283A (en) * 1993-12-01 1994-12-20 Flick; A. Bart Electrical therapeutic apparatus
US5743844A (en) * 1996-11-01 1998-04-28 Amei Technologies, Inc. High efficiency pulsed electromagnetic field (PEMF) stimulation therapy method and system
US6132362A (en) * 1996-11-01 2000-10-17 Amei Technologies, Inc. Pulsed electromagnetic field (PEMF) stimulation therapy system with bi-phasic coil
US6261221B1 (en) * 1996-11-01 2001-07-17 Amei Technologies Inc. Flexible coil pulsed electromagnetic field (PEMF) stimulation therapy system
US5968527A (en) * 1997-02-27 1999-10-19 Catholic University Of America, The Protection of living systems from the adverse effects of stress
US6083149A (en) 1997-10-22 2000-07-04 Emf Therapeutics, Inc. Magnetic field device and method for inhibiting angiogenesis and retarding growth rates of tumors in mammals
US6186940B1 (en) * 1998-05-18 2001-02-13 Robert N. Kirschbaum Energized trace elements
RU2147895C1 (ru) 1999-01-05 2000-04-27 Корж Геннадий Михайлович Способ лечения неосложненных переломов нижней челюсти
US6292699B1 (en) * 1999-01-29 2001-09-18 Electro-Biology, Inc. Direct current stimulation of spinal interbody fixation device
US6747004B1 (en) * 1999-04-29 2004-06-08 North Shore - Long Island Jewish Research Institute Method for inducing growth and enhancing survival of nervous tissue
US6923784B2 (en) 1999-04-30 2005-08-02 Medtronic, Inc. Therapeutic treatment of disorders based on timing information
DE19933719A1 (de) 1999-07-19 2001-01-25 Medigene Ag Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung
US7022506B2 (en) * 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
US7465546B2 (en) 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
US7465566B2 (en) * 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of genes via application of specific and selective electrical and electromagnetic signals
US6919205B2 (en) * 2000-02-23 2005-07-19 The Trustees Of The University Of Pennsylvania Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals
US7374916B2 (en) * 2000-02-23 2008-05-20 The Trustees Of The University Of Pennsylvania Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals
US7130692B2 (en) * 2000-02-23 2006-10-31 The Trustees Of The University Of Pennsylvania Portable electrotherapy device for treating osteoarthritis and other diseases, defects and injuries of the knee joint
US7429471B2 (en) * 2000-02-23 2008-09-30 The Trustees Of The University Of Pennsylvania Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals
US6485963B1 (en) * 2000-06-02 2002-11-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
AU2002227147A1 (en) * 2000-11-02 2002-05-15 Keith L March Method and system for modulation of oscillating signals to enhance biologic effects
US6485113B2 (en) * 2001-03-08 2002-11-26 Delphi Technologies, Inc. Haptic braking method and system
US7167753B2 (en) * 2001-07-03 2007-01-23 The Trustees Of The University Of Pennsylvania Device and method for electrically inducing osteogenesis in the spine
EP1465703A4 (en) * 2001-12-21 2007-05-23 Univ Pennsylvania "APPARATUS FOR TREATING OSTEOPOROSIS, HIP AND SPINAL FRACTURES AND FUSIONS WITH ELECTRIC FIELDS"
US6955642B1 (en) * 2002-11-26 2005-10-18 Ebi, Lp Pulsed electromagnetic field stimulation method and apparatus with improved dosing
US20050049640A1 (en) * 2003-05-12 2005-03-03 Gurtner Geoffrey C. Electromagnetic fields increase in vitro and in vivo angiogenesis through endothelial release of FGF-2
US20050084962A1 (en) * 2003-08-20 2005-04-21 Bruce Simon Methods of treatment using electromagnetic field stimulated stem cells
CA2545860A1 (en) * 2003-11-14 2005-06-02 The Trustees Of The University Of Pennsylvania Device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip
KR101324824B1 (ko) * 2004-01-12 2013-11-01 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 특이적이고 선택적인 전기 신호 및 전자기 신호에 의해생성된 장의 적용을 통해 골 세포에서의 골 형태형성단백질 (bmp) 유전자 발현을 상향-조절하는 시스템 및방법
US8034014B2 (en) * 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth

Also Published As

Publication number Publication date
US7981611B2 (en) 2011-07-19
EP2250250A1 (en) 2010-11-17
AU2009212561A1 (en) 2009-08-13
ZA201006311B (en) 2011-07-27
JP5596563B2 (ja) 2014-09-24
CA2712991A1 (en) 2009-08-13
RU2010137343A (ru) 2012-03-20
AU2009212561B2 (en) 2015-01-29
CN101939409A (zh) 2011-01-05
EP2250250A4 (en) 2011-08-24
WO2009100048A1 (en) 2009-08-13
US20080215116A1 (en) 2008-09-04
IL207430A0 (en) 2010-12-30
JP2011514813A (ja) 2011-05-12

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