IL207430A0 - Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields - Google Patents

Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields

Info

Publication number
IL207430A0
IL207430A0 IL207430A IL20743010A IL207430A0 IL 207430 A0 IL207430 A0 IL 207430A0 IL 207430 A IL207430 A IL 207430A IL 20743010 A IL20743010 A IL 20743010A IL 207430 A0 IL207430 A0 IL 207430A0
Authority
IL
Israel
Prior art keywords
fgf
regulation
specific
growth factor
application
Prior art date
Application number
IL207430A
Other languages
English (en)
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of IL207430A0 publication Critical patent/IL207430A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL207430A 2008-02-08 2010-08-05 Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields IL207430A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/028,530 US7981611B2 (en) 2000-02-23 2008-02-08 Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
PCT/US2009/032925 WO2009100048A1 (en) 2008-02-08 2009-02-03 Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric an electromagnetic fields

Publications (1)

Publication Number Publication Date
IL207430A0 true IL207430A0 (en) 2010-12-30

Family

ID=40952436

Family Applications (1)

Application Number Title Priority Date Filing Date
IL207430A IL207430A0 (en) 2008-02-08 2010-08-05 Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields

Country Status (11)

Country Link
US (1) US7981611B2 (enExample)
EP (1) EP2250250A4 (enExample)
JP (1) JP5596563B2 (enExample)
CN (1) CN101939409A (enExample)
AU (1) AU2009212561B2 (enExample)
CA (1) CA2712991A1 (enExample)
IL (1) IL207430A0 (enExample)
MX (1) MX2010008765A (enExample)
RU (1) RU2010137343A (enExample)
WO (1) WO2009100048A1 (enExample)
ZA (1) ZA201006311B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313908B2 (en) * 2000-02-23 2012-11-20 The Trustees Of The University Of Pennsylvania Regulation of stem cell gene production with specific and selective electric and electromagnetic fields
US10188858B2 (en) 2013-09-18 2019-01-29 University Of Cincinnati Method and device for treating a tissue with a high frequency electromagnetic field
WO2017118390A1 (zh) * 2016-01-05 2017-07-13 吴翔 利用变化电场磁场电磁场有选择地操控分子
US10806942B2 (en) 2016-11-10 2020-10-20 Qoravita LLC System and method for applying a low frequency magnetic field to biological tissues
US20240033509A1 (en) * 2022-08-01 2024-02-01 BonGenix, LLC Method and device for stimulating bone growth

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430999A (en) * 1981-11-10 1984-02-14 Trustees Of The University Of Pennsylvania Osteogenesis stimulating cathode assembly for use with an internal fixation device
US4506674A (en) * 1981-11-10 1985-03-26 Trustees Of The University Of Pennsylvania Method of stimulating osteogenesis with distributed port cathode
US4442846A (en) * 1981-11-10 1984-04-17 University Of Pennsylvania Distributed port bone-piercing cathode for electrically stimulated osteogenesis
US4509520A (en) * 1982-02-22 1985-04-09 Biolectron, Inc. Electrical stimulating apparatus
US4549547A (en) * 1982-07-27 1985-10-29 Trustees Of The University Of Pennsylvania Implantable bone growth stimulator
US4467809A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4467808A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for preventing and treating osteoporosis in a living body by using electrical stimulation non-invasively
US4487834A (en) * 1982-09-17 1984-12-11 Biolectron, Inc. Electrical stimulation of articular chondrocytes
US5269746A (en) * 1982-12-20 1993-12-14 Jacobson Jerry I Therapeutic treatment of mammals for epilepsy and Parkinson's disease
US4535775A (en) * 1983-02-10 1985-08-20 Biolectron, Inc. Method for treatment of non-union bone fractures by non-invasive electrical stimulation
IT1159024B (it) * 1983-06-02 1987-02-25 Ruggero Cadossi Metodo e dispositivo per il trattamento di tessuti e cellule viventi mediante campi elettromagnetici pulsanti
US4600010A (en) * 1984-10-04 1986-07-15 Biolectron, Inc. Electric stimulator and test instrument therefor
US4998532A (en) * 1986-05-23 1991-03-12 Lti Biomedical, Inc. Portable electro-therapy system
US5014699A (en) * 1986-05-23 1991-05-14 Trustees Of The University Of Pennsylvania Electromagnetic method and apparatus for healing living tissue
US6120502A (en) * 1988-06-13 2000-09-19 Michelson; Gary Karlin Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis
US5038797A (en) * 1990-02-20 1991-08-13 Romaine, Incorporated Electrical stimulation treatment device and method of use
US5273033A (en) 1991-09-19 1993-12-28 Murray Electronics Associates Limited Partnership Electrical stimulation for treatment of osteoarthritis
US5338286A (en) * 1992-12-08 1994-08-16 Electro-Biology, Inc. Electromagnetic bioresponse by selective spectral suppression in pulsed field stimulation
US5374283A (en) * 1993-12-01 1994-12-20 Flick; A. Bart Electrical therapeutic apparatus
US5743844A (en) * 1996-11-01 1998-04-28 Amei Technologies, Inc. High efficiency pulsed electromagnetic field (PEMF) stimulation therapy method and system
US6132362A (en) * 1996-11-01 2000-10-17 Amei Technologies, Inc. Pulsed electromagnetic field (PEMF) stimulation therapy system with bi-phasic coil
US6261221B1 (en) * 1996-11-01 2001-07-17 Amei Technologies Inc. Flexible coil pulsed electromagnetic field (PEMF) stimulation therapy system
US5968527A (en) * 1997-02-27 1999-10-19 Catholic University Of America, The Protection of living systems from the adverse effects of stress
US6083149A (en) 1997-10-22 2000-07-04 Emf Therapeutics, Inc. Magnetic field device and method for inhibiting angiogenesis and retarding growth rates of tumors in mammals
US6186940B1 (en) * 1998-05-18 2001-02-13 Robert N. Kirschbaum Energized trace elements
RU2147895C1 (ru) 1999-01-05 2000-04-27 Корж Геннадий Михайлович Способ лечения неосложненных переломов нижней челюсти
US6292699B1 (en) * 1999-01-29 2001-09-18 Electro-Biology, Inc. Direct current stimulation of spinal interbody fixation device
US6747004B1 (en) * 1999-04-29 2004-06-08 North Shore - Long Island Jewish Research Institute Method for inducing growth and enhancing survival of nervous tissue
US6923784B2 (en) 1999-04-30 2005-08-02 Medtronic, Inc. Therapeutic treatment of disorders based on timing information
DE19933719A1 (de) 1999-07-19 2001-01-25 Medigene Ag Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung
US7022506B2 (en) * 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
US7465546B2 (en) 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
US7465566B2 (en) * 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of genes via application of specific and selective electrical and electromagnetic signals
US6919205B2 (en) * 2000-02-23 2005-07-19 The Trustees Of The University Of Pennsylvania Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals
US7374916B2 (en) * 2000-02-23 2008-05-20 The Trustees Of The University Of Pennsylvania Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals
US7130692B2 (en) * 2000-02-23 2006-10-31 The Trustees Of The University Of Pennsylvania Portable electrotherapy device for treating osteoarthritis and other diseases, defects and injuries of the knee joint
US7429471B2 (en) * 2000-02-23 2008-09-30 The Trustees Of The University Of Pennsylvania Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals
US6485963B1 (en) * 2000-06-02 2002-11-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
AU2002227147A1 (en) * 2000-11-02 2002-05-15 Keith L March Method and system for modulation of oscillating signals to enhance biologic effects
US6485113B2 (en) * 2001-03-08 2002-11-26 Delphi Technologies, Inc. Haptic braking method and system
US7167753B2 (en) * 2001-07-03 2007-01-23 The Trustees Of The University Of Pennsylvania Device and method for electrically inducing osteogenesis in the spine
EP1465703A4 (en) * 2001-12-21 2007-05-23 Univ Pennsylvania "APPARATUS FOR TREATING OSTEOPOROSIS, HIP AND SPINAL FRACTURES AND FUSIONS WITH ELECTRIC FIELDS"
US6955642B1 (en) * 2002-11-26 2005-10-18 Ebi, Lp Pulsed electromagnetic field stimulation method and apparatus with improved dosing
US20050049640A1 (en) * 2003-05-12 2005-03-03 Gurtner Geoffrey C. Electromagnetic fields increase in vitro and in vivo angiogenesis through endothelial release of FGF-2
US20050084962A1 (en) * 2003-08-20 2005-04-21 Bruce Simon Methods of treatment using electromagnetic field stimulated stem cells
CA2545860A1 (en) * 2003-11-14 2005-06-02 The Trustees Of The University Of Pennsylvania Device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip
KR101324824B1 (ko) * 2004-01-12 2013-11-01 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 특이적이고 선택적인 전기 신호 및 전자기 신호에 의해생성된 장의 적용을 통해 골 세포에서의 골 형태형성단백질 (ｂｍｐ) 유전자 발현을 상향-조절하는 시스템 및방법
US8034014B2 (en) * 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth

Also Published As

Publication number Publication date
US7981611B2 (en) 2011-07-19
EP2250250A1 (en) 2010-11-17
MX2010008765A (es) 2010-09-30
AU2009212561A1 (en) 2009-08-13
ZA201006311B (en) 2011-07-27
JP5596563B2 (ja) 2014-09-24
CA2712991A1 (en) 2009-08-13
RU2010137343A (ru) 2012-03-20
AU2009212561B2 (en) 2015-01-29
CN101939409A (zh) 2011-01-05
EP2250250A4 (en) 2011-08-24
WO2009100048A1 (en) 2009-08-13
US20080215116A1 (en) 2008-09-04
JP2011514813A (ja) 2011-05-12

Similar Documents

Publication Publication Date Title
ZA200810486B (en) Regulation of transforming growth factor-beta (TGF-²) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
IL272587A (en) Adherent cells from placental tissue and their use in healing
GB2465291B (en) Human pluripotent stem cells and their medical use
GB201005548D0 (en) Neural tumor stem cells and methods of use thereof
HUE041510T2 (hu) Biológiai sejtek és szövetek krioprezervációja
IL206774A0 (en) Improved mammalian expression vectors and uses thereof
PL3323883T3 (pl) Zdefiniowane powierzchnie do hodowli komórkowej i sposoby użycia
IL231449A0 (en) Humanized tissues for in-vitro research uses, their arrays, and methods for their production
EP2134293A4 (en) INDUCTIVE HEATING OF WOVEN FABRIC WITH ALTERNATING MAGNETIC FIELDS AND THEIR USES
PL2158316T3 (pl) Ekspresja genowa oraz ból
PL2132562T3 (pl) Sposób oceniania komórek i hodowli komórkowych
PT2183024T (pt) Tratando parasitas com campos elétricos
IL243462A (en) Oligomers and phosphate-based conjugates for insertion of drugs into living cells and cell nuclei
EP2432462A4 (en) OXYGEN PROCEDURE AND COMPOSITIONS FOR THE TREATMENT OF MAMMALIAN DISEASES
PL2606120T3 (pl) Ludzkie komórki ułatwiające tolerancję i ich zastosowanie
IL207430A0 (en) Regulation of fibroblastic growth factor-2 (fgf-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
EP2227540A4 (en) DIFFERENTIATION OF HUMAN CELLS
EP2174341A4 (en) ION CONFINEMENT WITH FAST OSCILLATION ELECTRIC FIELDS
GB201001523D0 (en) Unitary Hair Clip and Method of Use
IL208579A0 (en) Methods and use of inducing a poptosis in cancer cells
ZA201209758B (en) Il-13 producing tr1-like cells and use thereof
GB0803153D0 (en) Insect attractants and their use in methods of insect control
EP2229446A4 (en) HYDROGENASE POLYPEPTIDE AND USE METHOD
GB0820397D0 (en) Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases
GB2456881B (en) Improvements in electric immersion heaters and their control for thermal stores