JP5588998B2 - 再設定可能な駆動機構を備えた固定用量注射デバイス - Google Patents

再設定可能な駆動機構を備えた固定用量注射デバイス Download PDF

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Publication number
JP5588998B2
JP5588998B2 JP2011542784A JP2011542784A JP5588998B2 JP 5588998 B2 JP5588998 B2 JP 5588998B2 JP 2011542784 A JP2011542784 A JP 2011542784A JP 2011542784 A JP2011542784 A JP 2011542784A JP 5588998 B2 JP5588998 B2 JP 5588998B2
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Japan
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dose
injection device
housing
drive member
piston rod
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JP2011542784A
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Japanese (ja)
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JP2012513266A5 (https=
JP2012513266A (ja
Inventor
デイヴィッド・プランプトリ
クリストファー・ジェイムズ・スミス
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2011542784A 2008-12-23 2009-12-18 再設定可能な駆動機構を備えた固定用量注射デバイス Active JP5588998B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08022317A EP2201972A1 (en) 2008-12-23 2008-12-23 Fixed dose injection device with resettable drive mechanism
EP08022317.5 2008-12-23
PCT/EP2009/067480 WO2010072662A1 (en) 2008-12-23 2009-12-18 Fixed dose injection device with resettable drive mechanism

Publications (3)

Publication Number Publication Date
JP2012513266A JP2012513266A (ja) 2012-06-14
JP2012513266A5 JP2012513266A5 (https=) 2013-01-31
JP5588998B2 true JP5588998B2 (ja) 2014-09-10

Family

ID=40584731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011542784A Active JP5588998B2 (ja) 2008-12-23 2009-12-18 再設定可能な駆動機構を備えた固定用量注射デバイス

Country Status (16)

Country Link
US (1) US8945069B2 (https=)
EP (2) EP2201972A1 (https=)
JP (1) JP5588998B2 (https=)
KR (1) KR20110099051A (https=)
CN (1) CN102325562B (https=)
AU (1) AU2009331633A1 (https=)
CA (1) CA2747324A1 (https=)
DK (1) DK2381984T3 (https=)
IL (1) IL213575A0 (https=)
MX (1) MX2011006534A (https=)
NZ (1) NZ593744A (https=)
RU (1) RU2514537C2 (https=)
SG (1) SG172319A1 (https=)
TW (1) TW201034712A (https=)
WO (1) WO2010072662A1 (https=)
ZA (1) ZA201103877B (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX373926B (es) 2009-05-27 2020-07-10 Ptc Therapeutics Inc Metodos para tratar cancer y estados no neoplasicos.
EP2292286A1 (en) * 2009-09-07 2011-03-09 Sanofi-Aventis Deutschland GmbH Drive mechanism for a medication delivery device and medication delivery device
DK2475411T3 (en) * 2009-09-07 2015-04-07 Sanofi Aventis Deutschland A drive mechanism for device for drug delivery
AR078457A1 (es) * 2009-09-30 2011-11-09 Sanofi Aventis Deutschland Mecanismo accionador para un dispositivo de descarga de farmacos
EP2482901B1 (en) 2009-09-30 2019-10-23 Sanofi-Aventis Deutschland GmbH Injection device
WO2011039202A1 (en) * 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device and reset member for a drive mechanism
DK2482889T3 (en) * 2009-09-30 2016-05-17 Sanofi Aventis Deutschland ACCOMMODATION drug delivery device
CN102548600B (zh) * 2009-09-30 2014-06-25 赛诺菲-安万特德国有限公司 给药装置和用于给药装置的驱动构件
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
EP2438950A1 (en) * 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
EP2438951A1 (en) * 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
EP2438949A1 (en) 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
TWI544941B (zh) * 2010-10-06 2016-08-11 賽諾菲阿凡提斯德意志有限公司 藥物傳送裝置的驅動機構及藥物傳送裝置
BR112013008882A2 (pt) * 2010-10-13 2017-07-11 Sanofi Aventis Deutschland mecanismo de definição de dose para um dispositivo de administração de fármaco e método de administração de pelo menos uma dose
TWI561265B (en) * 2010-10-13 2016-12-11 Sanofi Aventis Deutschland Dose setting mechanism and method of using same
JP6057991B2 (ja) * 2011-06-17 2017-01-11 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス用カートリッジ・ホルダ・アセンブリ
EP2885032B1 (en) * 2012-08-20 2018-01-31 Sanofi-Aventis Deutschland GmbH Drug delivery device and method for detecting contact between piston rod and cartridge bung via distance measurement
EP2885031B1 (en) * 2012-08-20 2017-10-04 Sanofi-Aventis Deutschland GmbH Drug delivery device and method for electrically detecting contact between piston rod and cartridge bung
US10201662B2 (en) 2013-04-10 2019-02-12 Sanofi Injection device and assembly method
BR112016002356B1 (pt) 2013-08-02 2022-04-05 Becton, Dickinson And Company Caneta de injeção
CN104436375A (zh) * 2014-12-30 2015-03-25 江苏华阳电器有限公司 一种注射笔
WO2019028171A1 (en) 2017-08-01 2019-02-07 Ptc Therapeutics, Inc. DHODH INHIBITOR FOR USE IN THE TREATMENT OF HEMATOLOGICAL CANCERS
US12121707B2 (en) 2018-09-08 2024-10-22 Shaily Engineering Plastics Limited Injection device
CN113301931B (zh) * 2019-01-18 2024-05-03 赛诺菲 注射装置
EP3972674A4 (en) * 2019-05-20 2023-02-08 The University Of Sydney DRUG DELIVERY DEVICE ADAPTER AND RELATED METHOD

Family Cites Families (10)

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US4475905A (en) * 1982-09-30 1984-10-09 Himmelstrup Anders B Injection device
GB9219849D0 (en) * 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
DK170604B1 (da) * 1993-12-07 1995-11-13 Niels Erik Holm Aps Doseringsenhed til dosering af afmålte mængder af en væske
DE69900026T2 (de) * 1998-01-30 2001-05-10 Novo Nordisk As Eine injektionsspritze
CA2378325C (en) * 1999-08-05 2008-09-30 Becton, Dickinson And Company Medication delivery pen
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
EP1819384A1 (en) * 2004-10-14 2007-08-22 Novo Nordisk A/S Syringe with dosis mechanism
PL1877119T3 (pl) * 2005-01-25 2019-03-29 Novo Nordisk A/S Urządzenie do wstrzykiwania z mechanizmem zwrotnym informującym o końcu dawki
WO2006114395A1 (en) * 2005-04-24 2006-11-02 Novo Nordisk A/S An injection device with a gearbox
EP1923084A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device

Also Published As

Publication number Publication date
DK2381984T3 (da) 2022-08-01
TW201034712A (en) 2010-10-01
EP2201972A1 (en) 2010-06-30
HK1161850A1 (en) 2012-08-10
KR20110099051A (ko) 2011-09-05
US8945069B2 (en) 2015-02-03
CA2747324A1 (en) 2010-07-01
AU2009331633A1 (en) 2011-07-14
RU2514537C2 (ru) 2014-04-27
EP2381984A1 (en) 2011-11-02
IL213575A0 (en) 2011-07-31
CN102325562A (zh) 2012-01-18
SG172319A1 (en) 2011-07-28
WO2010072662A1 (en) 2010-07-01
NZ593744A (en) 2013-11-29
CN102325562B (zh) 2014-07-16
RU2011130897A (ru) 2013-01-27
US20120046643A1 (en) 2012-02-23
MX2011006534A (es) 2011-07-13
JP2012513266A (ja) 2012-06-14
ZA201103877B (en) 2012-01-25
EP2381984B1 (en) 2022-05-11

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