JP5512534B2 - 骨塩密度関連の疾患の治療および診断の方法 - Google Patents
骨塩密度関連の疾患の治療および診断の方法 Download PDFInfo
- Publication number
- JP5512534B2 JP5512534B2 JP2010536471A JP2010536471A JP5512534B2 JP 5512534 B2 JP5512534 B2 JP 5512534B2 JP 2010536471 A JP2010536471 A JP 2010536471A JP 2010536471 A JP2010536471 A JP 2010536471A JP 5512534 B2 JP5512534 B2 JP 5512534B2
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- tbxas1
- acid
- mineral density
- txas
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- NGOWMZBCAKGGQE-NDENLUEZSA-N CC(C)(C)N/C(/Nc1cc(/C(/c2cccnc2)=C/CCCC(O)=O)ccc1)=N/NC Chemical compound CC(C)(C)N/C(/Nc1cc(/C(/c2cccnc2)=C/CCCC(O)=O)ccc1)=N/NC NGOWMZBCAKGGQE-NDENLUEZSA-N 0.000 description 1
- DSNBHJFQCNUKMA-SCKDECHMSA-N CCCCC[C@@H](/C=C/[C@H]1O[C@@H](C2)O[C@@H]2[C@@H]1C/C=C\CCCC(O)=O)O Chemical compound CCCCC[C@@H](/C=C/[C@H]1O[C@@H](C2)O[C@@H]2[C@@H]1C/C=C\CCCC(O)=O)O DSNBHJFQCNUKMA-SCKDECHMSA-N 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/52—Isomerases (5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/99—Other intramolecular oxidoreductases (5.3.99)
- C12Y503/99005—Thromboxane-A synthase (5.3.99.5)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07301643 | 2007-12-07 | ||
| EP07301643.8 | 2007-12-07 | ||
| PCT/EP2008/066880 WO2009071661A1 (en) | 2007-12-07 | 2008-12-05 | Methods for the treatment and diagnosis of bone mineral density related diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013254555A Division JP2014110788A (ja) | 2007-12-07 | 2013-12-09 | 骨塩密度関連の疾患の治療および診断の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507491A JP2011507491A (ja) | 2011-03-10 |
| JP2011507491A5 JP2011507491A5 (https=) | 2011-11-24 |
| JP5512534B2 true JP5512534B2 (ja) | 2014-06-04 |
Family
ID=39142026
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010536471A Expired - Fee Related JP5512534B2 (ja) | 2007-12-07 | 2008-12-05 | 骨塩密度関連の疾患の治療および診断の方法 |
| JP2013254555A Pending JP2014110788A (ja) | 2007-12-07 | 2013-12-09 | 骨塩密度関連の疾患の治療および診断の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013254555A Pending JP2014110788A (ja) | 2007-12-07 | 2013-12-09 | 骨塩密度関連の疾患の治療および診断の方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20100284991A1 (https=) |
| EP (1) | EP2227560B1 (https=) |
| JP (2) | JP5512534B2 (https=) |
| ES (1) | ES2655209T3 (https=) |
| WO (1) | WO2009071661A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009071661A1 (en) | 2007-12-07 | 2009-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment and diagnosis of bone mineral density related diseases |
| KR102845511B1 (ko) * | 2019-02-08 | 2025-08-12 | 삼성디스플레이 주식회사 | 축합환 화합물 및 이를 포함한 유기 발광 소자 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN445095A0 (en) * | 1995-07-27 | 1995-08-17 | Garvan Institute Of Medical Research | Method of predicting bone density |
| JP2008534473A (ja) * | 2005-03-23 | 2008-08-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | トロンボキサン受容体拮抗薬及びトロンボキサンシンターゼ阻害薬の組み合わせ及びcox−2阻害薬を含む組成物 |
| EP2069326B1 (en) * | 2006-10-04 | 2015-03-18 | Merck Sharp & Dohme Corp. | Bicyclic and tricyclic derivatives as thrombin receptor antagonists |
| WO2009071661A1 (en) | 2007-12-07 | 2009-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment and diagnosis of bone mineral density related diseases |
-
2008
- 2008-12-05 WO PCT/EP2008/066880 patent/WO2009071661A1/en not_active Ceased
- 2008-12-05 EP EP08856341.6A patent/EP2227560B1/en active Active
- 2008-12-05 ES ES08856341.6T patent/ES2655209T3/es active Active
- 2008-12-05 US US12/746,456 patent/US20100284991A1/en not_active Abandoned
- 2008-12-05 JP JP2010536471A patent/JP5512534B2/ja not_active Expired - Fee Related
-
2013
- 2013-12-09 JP JP2013254555A patent/JP2014110788A/ja active Pending
-
2014
- 2014-12-19 US US14/577,177 patent/US9834820B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014110788A (ja) | 2014-06-19 |
| JP2011507491A (ja) | 2011-03-10 |
| EP2227560B1 (en) | 2017-10-18 |
| ES2655209T3 (es) | 2018-02-19 |
| WO2009071661A1 (en) | 2009-06-11 |
| US20100284991A1 (en) | 2010-11-11 |
| EP2227560A1 (en) | 2010-09-15 |
| US20150104437A1 (en) | 2015-04-16 |
| US9834820B2 (en) | 2017-12-05 |
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