JP5502482B2 - 回転可能試験素子 - Google Patents

回転可能試験素子 Download PDF

Info

Publication number
JP5502482B2
JP5502482B2 JP2009529607A JP2009529607A JP5502482B2 JP 5502482 B2 JP5502482 B2 JP 5502482B2 JP 2009529607 A JP2009529607 A JP 2009529607A JP 2009529607 A JP2009529607 A JP 2009529607A JP 5502482 B2 JP5502482 B2 JP 5502482B2
Authority
JP
Japan
Prior art keywords
sample
test element
zone
liquid
capillary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2009529607A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010505096A5 (https=
JP2010505096A (ja
Inventor
ベーム，クリストフ
オランス，ノルベルト
シュピンケ，ユルゲン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2010505096A publication Critical patent/JP2010505096A/ja
Publication of JP2010505096A5 publication Critical patent/JP2010505096A5/ja
Application granted granted Critical
Publication of JP5502482B2 publication Critical patent/JP5502482B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/082—Active control of flow resistance, e.g. flow controllers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/110833—Utilizing a moving indicator strip or tape
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2009529607A 2006-09-27 2007-09-27 回転可能試験素子 Active JP5502482B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06020219A EP1916524A1 (de) 2006-09-27 2006-09-27 Rotierbares Testelement
EP06020219.9 2006-09-27
PCT/EP2007/008419 WO2008037469A1 (de) 2006-09-27 2007-09-27 Rotierbares testelement

Publications (3)

Publication Number Publication Date
JP2010505096A JP2010505096A (ja) 2010-02-18
JP2010505096A5 JP2010505096A5 (https=) 2010-06-17
JP5502482B2 true JP5502482B2 (ja) 2014-05-28

Family

ID=37719401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009529607A Active JP5502482B2 (ja) 2006-09-27 2007-09-27 回転可能試験素子

Country Status (7)

Country Link
US (1) US8470588B2 (https=)
EP (3) EP1916524A1 (https=)
JP (1) JP5502482B2 (https=)
CN (1) CN101517413B (https=)
CA (1) CA2664565C (https=)
ES (2) ES2724734T3 (https=)
WO (1) WO2008037469A1 (https=)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8632243B2 (en) * 2008-03-10 2014-01-21 The Hong Kong Polytechnic University Microfluidic mixing using continuous acceleration/deceleration methodology
EP2133149A1 (en) * 2008-06-13 2009-12-16 F.Hoffmann-La Roche Ag Lab-on-disc device
EP2145682A1 (de) * 2008-07-18 2010-01-20 Roche Diagnostics GmbH Testelement zur Analyse einer Körperflüssigkeitsprobe auf einen darin enthaltenen Analyten, Analysesystem und Verfahren zur Steuerung der Bewegung einer in einem Kanal eines Testelements enthaltenen Flüssigkeit
EP2198964B8 (de) 2008-11-06 2013-04-24 F. Hoffmann-La Roche AG Verfahren zum Bereitstellen eines getrockneten Reagenz in einem mikrofluidischen System
EP2194381B1 (de) * 2008-12-03 2015-12-02 Roche Diagnostics GmbH Testelement mit kombinierter Kontroll- und Kalibrationszone
GB2473425A (en) * 2009-09-03 2011-03-16 Vivacta Ltd Fluid Sample Collection Device
EP2329877A1 (de) * 2009-12-04 2011-06-08 Roche Diagnostics GmbH Mikrofluidisches Element zur Analyse einer Flüssigkeitsprobe
KR101722548B1 (ko) * 2010-01-29 2017-04-03 삼성전자주식회사 원심력기반의 미세유동장치 및 이를 이용한 유체시료 내 분석대상물질 검출방법
EP2369324A1 (de) 2010-03-23 2011-09-28 F. Hoffmann-La Roche AG Verfahren zur Herstellen eines analytischen Testelementes, analytisches Testelement, Verwendung eines analytischen Testelementes sowie analytisches Testsystem
DE102010013752A1 (de) 2010-03-31 2011-10-06 Roche Diagnostics Gmbh Multifunktionelle Detektionsküvette
JP5728217B2 (ja) 2010-12-14 2015-06-03 ローム株式会社 マイクロチップおよびそれを用いた検査または分析方法
US11648561B2 (en) 2012-02-13 2023-05-16 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
WO2013123035A1 (en) 2012-02-13 2013-08-22 Molecular Systems Corporation System and method for processing and detecting nucleic acids
US11485968B2 (en) 2012-02-13 2022-11-01 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
US10668622B2 (en) * 2012-10-11 2020-06-02 Siemens Healthcare Diagnostics Inc. Automation maintenance carrier
US20140120544A1 (en) 2012-10-25 2014-05-01 Neumodx Molecular, Inc. Method and materials for isolation of nucleic acid materials
EP2777499B1 (en) 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Rotatable fluid sample collection device
EP3135377A1 (en) 2013-04-15 2017-03-01 Becton, Dickinson and Company Biological fluid collection device and biological fluid separation and testing system
CA3005826C (en) * 2013-04-15 2021-11-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
SG11201601273RA (en) * 2013-08-23 2016-03-30 Daktari Diagnostics Inc Microfluidic metering of fluids
EP3077806B1 (en) * 2013-12-06 2019-09-11 Ortho Clinical Diagnostics, Inc. Assay device having a wash port
EP2944965A1 (en) 2014-05-13 2015-11-18 Roche Diagnostics GmbH Rotatable cartridge for measuring a property of a biological sample
EP2952258A1 (en) 2014-06-06 2015-12-09 Roche Diagnostics GmbH Rotatable cartridge for analyzing a biological sample
EP2952257A1 (en) 2014-06-06 2015-12-09 Roche Diagnostics GmbH Rotatable cartridge for processing and analyzing a biological sample
JP6527531B2 (ja) * 2014-06-06 2019-06-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 生体試料を分析するための計量チャンバを備える回転可能なカートリッジ
EP2957890A1 (en) * 2014-06-16 2015-12-23 Roche Diagnostics GmbH Cartridge with a rotatable lid
CN107110842B (zh) * 2014-10-30 2020-04-10 通用电气健康护理生物科学股份公司 确定溶剂校正曲线的方法
JP6600861B2 (ja) * 2015-04-08 2019-11-06 株式会社パートナーファーム 固相反応チップ及びこれを用いた測定方法
WO2017044732A1 (en) * 2015-09-09 2017-03-16 Northwestern University Devices, systems, and methods for specimen preparation using capillary and centrifugal forces
EP3173149A1 (en) * 2015-11-26 2017-05-31 Roche Diagnostics GmbH Determining a quantity of an analyte in a blood sample
EP3184158B1 (en) 2015-12-21 2019-01-16 Roche Diagniostics GmbH Blood collector with capillary structure
CN107192819A (zh) * 2016-03-14 2017-09-22 北京康华源科技发展有限公司 一种离心分离检测方法
EP3431990A4 (en) * 2016-03-14 2019-12-04 Beijing Kanghuayuan Sci-Tech Company Ltd METHOD AND DEVICE FOR CENTRIFUGATION RECOGNITION
EP4023338B1 (en) 2016-04-14 2024-10-02 Roche Diagnostics GmbH Cartridge and optical measurement of an analyte with said cartridge
US11815440B2 (en) * 2016-05-02 2023-11-14 Danmarks Tekniske Universitet Method for preparing a substrate by applying a sample to be analysed
KR101868961B1 (ko) * 2016-06-21 2018-06-19 울산과학기술원 미세 유체 장치
EP3324189B1 (en) 2016-11-16 2021-01-06 Roche Diagnostics GmbH Rotatable cartridge with multiple metering chambers
JP2020514725A (ja) * 2017-01-20 2020-05-21 ユニヴァルシテ リブレ デ ブリュッセル イムノアッセイ方法および装置
CN111433606B (zh) * 2017-02-09 2024-05-24 上海宜晟生物科技有限公司 采用不同间距高度的测定
WO2018165440A1 (en) * 2017-03-08 2018-09-13 Northwestern University Devices, systems, and methods for specimen preparation and analysis using capillary and centrifugal forces
CN107525923A (zh) * 2017-04-01 2017-12-29 北京康华源科技发展有限公司 一种离心分离免疫层析检测方法及装置
WO2018177445A1 (zh) * 2017-04-01 2018-10-04 北京康华源科技发展有限公司 一种离心分离免疫层析检测方法及装置
KR102176479B1 (ko) 2017-11-20 2020-11-09 주식회사 엘지화학 회전식 디스크 시스템을 활용한 중금속 정성 및 정량 분석 디바이스 및 분석 방법
US11433390B2 (en) * 2017-12-07 2022-09-06 Ion Llc Methods and systems for a capillary device
JP6846388B2 (ja) * 2018-06-26 2021-03-24 シスメックス株式会社 測定用カートリッジおよび送液方法
CN110614126B (zh) * 2018-06-28 2021-04-09 北京中科生仪科技有限公司 一种实现光学检测的微流控芯片及其制作方法
SE542462C2 (en) 2018-09-20 2020-05-12 Astrego Diagnostics Ab Sample loading cartridge for a microfluidic device
CN111207242B (zh) 2020-04-18 2020-09-01 博奥生物集团有限公司 流体驱动控制阀及使用方法
US12582984B1 (en) 2020-07-02 2026-03-24 Argonaut Manufacturing Services, Inc. Method for lyophilization and device thereof
KR102433675B1 (ko) * 2020-07-02 2022-08-18 주식회사 클리노믹스 입자 여과 장치 및 입자 여과 방법
BE1029228B1 (fr) * 2021-03-22 2022-10-18 Unisensor Dispositif microfluidique
CN115608429B (zh) * 2022-09-15 2026-01-13 西北工业大学 用于定量取样的微流控芯片
AU2024299577A1 (en) * 2023-07-21 2026-01-22 Vital Biosciences Inc. Methods and devices for biological sample preparation and microscopic analysis
WO2025132558A1 (fr) * 2023-12-21 2025-06-26 Commissariat A L'energie Atomique Et Aux Energies Alternatives Collecteur d'échantillons liquides sur papier pour des systèmes microfluidiques, système microfluidique associé
DE202024001130U1 (de) 2024-06-12 2024-07-22 Axel Hochstetter Mikrofluidisches Bauteil zur passiven Separation von Partikeln und Zellen

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5242606A (en) * 1990-06-04 1993-09-07 Abaxis, Incorporated Sample metering port for analytical rotor having overflow chamber
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US6235531B1 (en) * 1993-09-01 2001-05-22 Abaxis, Inc. Modified siphons for improved metering precision
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
IL108159A (en) * 1993-12-23 1998-02-08 Orgenics Ltd Apparatus for separation, concentration and detection of target molecules in liquid sample
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
US20020076354A1 (en) 2000-12-01 2002-06-20 Cohen David Samuel Apparatus and methods for separating components of particulate suspension
EP1390144A2 (en) * 2001-03-19 2004-02-25 Gyros AB Structural units that define fluidic functions
CN101158695A (zh) * 2002-12-04 2008-04-09 斯宾克斯公司 流体的可程控微量控制用方法
US20050014249A1 (en) 2003-02-21 2005-01-20 Norbert Staimer Chromatographic analysis on optical bio-discs and methods relating thereto
WO2004095034A1 (en) 2003-04-23 2004-11-04 Nagaoka & Co., Ltd. Optical bio-discs including spiral fluidic circuits for performing assays
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US20070166721A1 (en) 2003-06-27 2007-07-19 Phan Brigitte C Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
WO2005009581A2 (en) * 2003-07-15 2005-02-03 Nagaoka & Co. Ltd. Methods and apparatus for blood separation and analysis using membranes on an optical bio-disc
JP4646204B2 (ja) * 2005-01-27 2011-03-09 ブラザー工業株式会社 検査対象受体、分取装置、及び分取方法

Also Published As

Publication number Publication date
EP2069787A1 (de) 2009-06-17
ES2724734T3 (es) 2019-09-13
HK1136626A1 (en) 2010-07-02
WO2008037469A1 (de) 2008-04-03
EP2069787B1 (de) 2019-03-06
US20090191643A1 (en) 2009-07-30
ES2933349T3 (es) 2023-02-06
CA2664565C (en) 2014-04-01
CN101517413B (zh) 2013-11-06
CN101517413A (zh) 2009-08-26
EP1916524A1 (de) 2008-04-30
US8470588B2 (en) 2013-06-25
EP3524982B1 (de) 2022-10-19
EP3524982A1 (de) 2019-08-14
JP2010505096A (ja) 2010-02-18
CA2664565A1 (en) 2008-04-03

Similar Documents

Publication Publication Date Title
JP5502482B2 (ja) 回転可能試験素子
KR101722548B1 (ko) 원심력기반의 미세유동장치 및 이를 이용한 유체시료 내 분석대상물질 검출방법
EP1768783B1 (en) Controlled flow assay device and method
KR101519379B1 (ko) 원심력 기반의 미세유동장치 및 이를 이용한 면역분석방법
EP3674713A1 (en) Microfluidic detection chip and manufacturing method therefor, fixing device, and centrifugal detection device
US8137905B2 (en) Apparatus and method for determining an analyte in a fluid
EP2957890A1 (en) Cartridge with a rotatable lid
KR20120125220A (ko) 마이크로유체 검정 플랫폼
WO2002043866A2 (en) Apparatus and methods for separating components of particulate suspension
KR20110079570A (ko) 박막 원심분리 분석 장치 및 이를 이용한 분석 방법
JP5423200B2 (ja) 分析チップおよび検体の分析方法
AU2010337438A1 (en) Sample processing cartridge and method of processing and/or analysing a sample under centrifugal force
CN108072764B (zh) 具有多个计量腔室的可旋转筒
JP5125680B2 (ja) 分離チップおよび分離方法
Furutani et al. Rapid enzyme-linked immunosorbent assays for diagnosis of diabetes in a compact disc-shaped microfluidic device
JP2023524069A (ja) 試料分析のためのシステム及び方法
HK1136626B (en) Rotatable test element

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100420

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100420

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20120119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120124

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120413

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120420

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120709

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130507

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130730

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130806

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130820

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140311

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140313

R150 Certificate of patent or registration of utility model

Ref document number: 5502482

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250