JP5487117B2 - ニューロテンシン受容体3に由来するペプチドおよび精神疾患の治療におけるその使用 - Google Patents

ニューロテンシン受容体3に由来するペプチドおよび精神疾患の治療におけるその使用 Download PDF

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Publication number
JP5487117B2
JP5487117B2 JP2010538844A JP2010538844A JP5487117B2 JP 5487117 B2 JP5487117 B2 JP 5487117B2 JP 2010538844 A JP2010538844 A JP 2010538844A JP 2010538844 A JP2010538844 A JP 2010538844A JP 5487117 B2 JP5487117 B2 JP 5487117B2
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Prior art keywords
peptide
trek
mice
ntsr3
depression
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JP2010538844A
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English (en)
Japanese (ja)
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JP2011505864A5 (enExample
JP2011505864A (ja
Inventor
マゼラ、ジャン
ペトロルト、オリヴィエ
ボルソット、マルク
オルトー、カトリーヌ
ヴィドマン、カトリーヌ
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Centre National de la Recherche Scientifique CNRS
Universite de Nice Sophia Antipolis UNSA
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Centre National de la Recherche Scientifique CNRS
Universite de Nice Sophia Antipolis UNSA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2010538844A 2007-12-21 2008-12-18 ニューロテンシン受容体3に由来するペプチドおよび精神疾患の治療におけるその使用 Active JP5487117B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07291602.6 2007-12-21
EP07291602A EP2077278A1 (fr) 2007-12-21 2007-12-21 Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques
PCT/FR2008/001784 WO2009103898A1 (fr) 2007-12-21 2008-12-18 Peptide derive du recepteur 3 de la neurotensine et utilisation dans le traitement de maladies psychiatriques

Publications (3)

Publication Number Publication Date
JP2011505864A JP2011505864A (ja) 2011-03-03
JP2011505864A5 JP2011505864A5 (enExample) 2012-02-16
JP5487117B2 true JP5487117B2 (ja) 2014-05-07

Family

ID=39304741

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010538844A Active JP5487117B2 (ja) 2007-12-21 2008-12-18 ニューロテンシン受容体3に由来するペプチドおよび精神疾患の治療におけるその使用

Country Status (7)

Country Link
US (1) US8252748B2 (enExample)
EP (2) EP2077278A1 (enExample)
JP (1) JP5487117B2 (enExample)
AT (1) ATE535543T1 (enExample)
CA (1) CA2709907C (enExample)
ES (1) ES2377489T3 (enExample)
WO (1) WO2009103898A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077278A1 (fr) * 2007-12-21 2009-07-08 Centre National de la Recherche Scientifique (CNRS) Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques
EP3099313B1 (en) 2014-01-27 2021-04-21 Centre National De La Recherche Scientifique Retro-inverso analogs of spadin display increased antidepressant effects
CA3006313C (en) * 2015-11-24 2020-02-11 Transfert Plus, S.E.C. Peptide compounds and peptide conjugates for the treatment of cancer through receptor-mediated chemotherapy
FR3057267A1 (fr) 2016-10-11 2018-04-13 Centre National De La Recherche Scientifique - Cnrs - Procede de diagnostic/determination de l'efficacite de traitement de la depression
FR3057266B1 (fr) * 2016-10-11 2021-05-21 Centre Nat Rech Scient Peptides derives du propeptide ntsr3 et leur utilisation dans le traitement de la depression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051485A1 (en) * 1998-01-27 2000-11-15 Smithkline Beecham Plc Trek-1 like two pore potassium channel
DK1891966T3 (da) * 2002-12-20 2012-04-02 Lundbeck & Co As H Modulation af neurotrophinaktivitet; fremgangsmåde til screening
EP2077278A1 (fr) * 2007-12-21 2009-07-08 Centre National de la Recherche Scientifique (CNRS) Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques

Also Published As

Publication number Publication date
CA2709907A1 (fr) 2009-08-27
US8252748B2 (en) 2012-08-28
EP2229408B1 (fr) 2011-11-30
US20110237515A1 (en) 2011-09-29
CA2709907C (fr) 2016-11-08
EP2229408A1 (fr) 2010-09-22
EP2077278A1 (fr) 2009-07-08
ES2377489T3 (es) 2012-03-28
JP2011505864A (ja) 2011-03-03
WO2009103898A1 (fr) 2009-08-27
ATE535543T1 (de) 2011-12-15

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