ATE535543T1 - Aus dem neurotensin-rezeptor 3 entwickeltes peptid und seine verwendung bei der behandlung psychischer krankheiten - Google Patents
Aus dem neurotensin-rezeptor 3 entwickeltes peptid und seine verwendung bei der behandlung psychischer krankheitenInfo
- Publication number
- ATE535543T1 ATE535543T1 AT08872504T AT08872504T ATE535543T1 AT E535543 T1 ATE535543 T1 AT E535543T1 AT 08872504 T AT08872504 T AT 08872504T AT 08872504 T AT08872504 T AT 08872504T AT E535543 T1 ATE535543 T1 AT E535543T1
- Authority
- AT
- Austria
- Prior art keywords
- neurotensin receptor
- ntsr3
- ligand
- nucleic acid
- peptide
- Prior art date
Links
- 102100032889 Sortilin Human genes 0.000 title abstract 7
- 108010014657 sortilin Proteins 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000003340 mental effect Effects 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- ADSGHMXEAZJJNF-DCAQKATOSA-N Ala-Pro-Leu Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N ADSGHMXEAZJJNF-DCAQKATOSA-N 0.000 abstract 1
- VOBYAKCXGQQFLR-LSJOCFKGSA-N Ile-Gly-Val Chemical compound CC[C@H](C)[C@H](N)C(=O)NCC(=O)N[C@@H](C(C)C)C(O)=O VOBYAKCXGQQFLR-LSJOCFKGSA-N 0.000 abstract 1
- NUZHSNLQJDYSRW-BZSNNMDCSA-N Pro-Arg-Trp Chemical compound [H]N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O NUZHSNLQJDYSRW-BZSNNMDCSA-N 0.000 abstract 1
- KDGARKCAKHBEDB-NKWVEPMBSA-N Ser-Gly-Pro Chemical compound C1C[C@@H](N(C1)C(=O)CNC(=O)[C@H](CO)N)C(=O)O KDGARKCAKHBEDB-NKWVEPMBSA-N 0.000 abstract 1
- BCAVNDNYOGTQMQ-AAEUAGOBSA-N Ser-Trp-Gly Chemical compound [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(O)=O BCAVNDNYOGTQMQ-AAEUAGOBSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 108010057821 leucylproline Proteins 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07291602A EP2077278A1 (fr) | 2007-12-21 | 2007-12-21 | Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques |
| PCT/FR2008/001784 WO2009103898A1 (fr) | 2007-12-21 | 2008-12-18 | Peptide derive du recepteur 3 de la neurotensine et utilisation dans le traitement de maladies psychiatriques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE535543T1 true ATE535543T1 (de) | 2011-12-15 |
Family
ID=39304741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08872504T ATE535543T1 (de) | 2007-12-21 | 2008-12-18 | Aus dem neurotensin-rezeptor 3 entwickeltes peptid und seine verwendung bei der behandlung psychischer krankheiten |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8252748B2 (enExample) |
| EP (2) | EP2077278A1 (enExample) |
| JP (1) | JP5487117B2 (enExample) |
| AT (1) | ATE535543T1 (enExample) |
| CA (1) | CA2709907C (enExample) |
| ES (1) | ES2377489T3 (enExample) |
| WO (1) | WO2009103898A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2077278A1 (fr) * | 2007-12-21 | 2009-07-08 | Centre National de la Recherche Scientifique (CNRS) | Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques |
| CA2938019A1 (en) * | 2014-01-27 | 2015-07-30 | Centre National De La Recherche Scientifique | Retro-inverso analogs of spadin display increased antidepressant effects |
| PT3380495T (pt) | 2015-11-24 | 2021-08-19 | Transfert Plus Sec | Compostos peptídicos e conjugados peptídicos para o tratamento de cancro através de quimioterapia mediada por recetores |
| FR3057267A1 (fr) | 2016-10-11 | 2018-04-13 | Centre National De La Recherche Scientifique - Cnrs - | Procede de diagnostic/determination de l'efficacite de traitement de la depression |
| FR3057266B1 (fr) * | 2016-10-11 | 2021-05-21 | Centre Nat Rech Scient | Peptides derives du propeptide ntsr3 et leur utilisation dans le traitement de la depression |
| US12662512B2 (en) | 2019-10-22 | 2026-06-23 | Genethon | Chimeric polypeptides and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999037762A1 (en) * | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Trek-1 like two pore potassium channel |
| DK1891966T3 (da) * | 2002-12-20 | 2012-04-02 | Lundbeck & Co As H | Modulation af neurotrophinaktivitet; fremgangsmåde til screening |
| EP2077278A1 (fr) | 2007-12-21 | 2009-07-08 | Centre National de la Recherche Scientifique (CNRS) | Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques |
-
2007
- 2007-12-21 EP EP07291602A patent/EP2077278A1/fr not_active Withdrawn
-
2008
- 2008-12-18 WO PCT/FR2008/001784 patent/WO2009103898A1/fr not_active Ceased
- 2008-12-18 AT AT08872504T patent/ATE535543T1/de active
- 2008-12-18 JP JP2010538844A patent/JP5487117B2/ja active Active
- 2008-12-18 US US12/809,884 patent/US8252748B2/en active Active
- 2008-12-18 EP EP08872504A patent/EP2229408B1/fr active Active
- 2008-12-18 ES ES08872504T patent/ES2377489T3/es active Active
- 2008-12-18 CA CA2709907A patent/CA2709907C/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20110237515A1 (en) | 2011-09-29 |
| JP2011505864A (ja) | 2011-03-03 |
| CA2709907A1 (fr) | 2009-08-27 |
| EP2229408B1 (fr) | 2011-11-30 |
| ES2377489T3 (es) | 2012-03-28 |
| US8252748B2 (en) | 2012-08-28 |
| EP2077278A1 (fr) | 2009-07-08 |
| WO2009103898A1 (fr) | 2009-08-27 |
| CA2709907C (fr) | 2016-11-08 |
| EP2229408A1 (fr) | 2010-09-22 |
| JP5487117B2 (ja) | 2014-05-07 |
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