JP5470050B2 - アルツハイマー型老年認知症の治療方法 - Google Patents
アルツハイマー型老年認知症の治療方法 Download PDFInfo
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- JP5470050B2 JP5470050B2 JP2009548551A JP2009548551A JP5470050B2 JP 5470050 B2 JP5470050 B2 JP 5470050B2 JP 2009548551 A JP2009548551 A JP 2009548551A JP 2009548551 A JP2009548551 A JP 2009548551A JP 5470050 B2 JP5470050 B2 JP 5470050B2
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- acyl
- alkyl
- sdat
- therapeutic agent
- plasmenyl
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88888307P | 2007-02-08 | 2007-02-08 | |
| US60/888,883 | 2007-02-08 | ||
| PCT/CA2007/001472 WO2008095275A1 (en) | 2007-02-08 | 2007-08-27 | Methods for the treatment of senile dementia of the alzheimer's type |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010518029A JP2010518029A (ja) | 2010-05-27 |
| JP2010518029A5 JP2010518029A5 (https=) | 2010-10-21 |
| JP5470050B2 true JP5470050B2 (ja) | 2014-04-16 |
Family
ID=39537686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548551A Active JP5470050B2 (ja) | 2007-02-08 | 2007-08-27 | アルツハイマー型老年認知症の治療方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US9034923B2 (https=) |
| EP (2) | EP2620147B1 (https=) |
| JP (1) | JP5470050B2 (https=) |
| AU (1) | AU2007346587C1 (https=) |
| CA (2) | CA2695167C (https=) |
| IL (1) | IL200029A0 (https=) |
| SG (1) | SG173418A1 (https=) |
| WO (1) | WO2008095275A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2620147B1 (en) | 2007-02-08 | 2020-06-03 | Med-Life Discoveries LP | Compounds for lowering cholesterol |
| TWI475989B (zh) | 2008-12-22 | 2015-03-11 | Phenomenome Discoveries Inc | 縮醛磷脂類化合物,含彼之醫藥組成物以及治療老化疾病的方法 |
| SG10201405975VA (en) | 2009-10-01 | 2014-11-27 | Phenomenome Discoveries Inc | Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis |
| EP3684463B1 (en) | 2017-09-19 | 2025-05-14 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement |
| US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
| US11478603B2 (en) | 2017-12-31 | 2022-10-25 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to enhance emotional response |
| US12280219B2 (en) | 2017-12-31 | 2025-04-22 | NeuroLight, Inc. | Method and apparatus for neuroenhancement to enhance emotional response |
| US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
| CN113382683A (zh) | 2018-09-14 | 2021-09-10 | 纽罗因恒思蒙特实验有限责任公司 | 改善睡眠的系统和方法 |
| US11786694B2 (en) | 2019-05-24 | 2023-10-17 | NeuroLight, Inc. | Device, method, and app for facilitating sleep |
| CN114236019B (zh) * | 2022-02-24 | 2022-05-06 | 宝枫生物科技(北京)有限公司 | 脑白质病变的生物标志物的应用 |
| WO2025057966A1 (ja) * | 2023-09-12 | 2025-03-20 | シンバイオシス・ソリューションズ株式会社 | 軽度認知障害の予防又は改善用の食品 |
| CN118512461A (zh) * | 2024-06-03 | 2024-08-20 | 东莞市第八人民医院(东莞市儿童医院) | 一种母乳来源磷脂在防治支气管肺发育不良的应用 |
| CN119876292B (zh) * | 2025-03-27 | 2025-06-03 | 浙江省白马湖实验室有限公司 | 一种酰胺类缩醛磷脂化合物的制备方法及应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994009371A1 (en) | 1992-10-09 | 1994-04-28 | Massachusetts Institute Of Technology | Antemortem diagnostic test for alzheimer's disease |
| FR2736265B1 (fr) | 1995-07-07 | 1997-09-26 | Forgeot Marcel | Nouvelles compositions a base de phosphoglycero ethers et leur utilisation dans le traitement des maladies neuro-degeneratives |
| US5731354A (en) | 1996-05-06 | 1998-03-24 | Clarion Pharmaceuticals Inc. | Treatment for the inhibition of neuro-degenerative disease states |
| US6177476B1 (en) | 1998-08-27 | 2001-01-23 | Clarion Pharmaceuticals Inc. | Nutritional supplements for replenishing plasmalogens |
| CA2298181C (en) | 2000-02-02 | 2006-09-19 | Dayan Burke Goodnough | Non-targeted complex sample analysis |
| US20020009740A1 (en) | 2000-04-14 | 2002-01-24 | Rima Kaddurah-Daouk | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| WO2002021139A2 (en) | 2000-09-08 | 2002-03-14 | Oxford Glycosciences (Uk) Ltd. | Automated identification of peptides |
| US6838452B2 (en) * | 2000-11-24 | 2005-01-04 | Vascular Biogenics Ltd. | Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis |
| DE10291524D2 (de) | 2001-04-06 | 2004-07-01 | Anker Thorsten | Verfahren zum Nachweis chronisch-demenzieller Erkrankungen, zugehörige Peptide und Nachweisreagenzien |
| CA2446666A1 (en) | 2001-05-09 | 2002-11-14 | Biovision Ag | Method for detecting progredient chronic dementia, and associated peptides and detection reagents |
| US7348143B2 (en) | 2002-03-22 | 2008-03-25 | Phenmenome Discoveries Inc. | Method of visualizing non-targeted metabolomic data generated from fourier transform ion cyclotron resonance mass spectrometers |
| JP2004026803A (ja) | 2002-03-29 | 2004-01-29 | Nof Corp | 神経細胞死予防剤 |
| PT1535076E (pt) | 2002-08-23 | 2008-11-03 | Bayer Healthcare Ag | Marcadores biológicos para diagnóstico da doença de alzheimer |
| SE0203886D0 (sv) * | 2002-12-27 | 2002-12-27 | Ltp Lipid Technologies Provide | Glycerolesterprodukt och dess användning |
| US20040191294A1 (en) * | 2003-03-27 | 2004-09-30 | Ramaprasad Talahalli Ravichandra | Health composition |
| JPWO2004093910A1 (ja) | 2003-04-22 | 2006-07-13 | アステラス製薬株式会社 | PPARδアゴニストによる脳神経変性疾患治療剤 |
| JP4796967B2 (ja) | 2003-11-07 | 2011-10-19 | ヴァーミリオン インコーポレイテッド | アルツハイマー病のためのバイオマーカー |
| WO2005085838A2 (en) | 2004-03-02 | 2005-09-15 | Vanderbilt University | Computational analysis of mass spectroscopic lipid data |
| WO2005116659A2 (en) | 2004-05-18 | 2005-12-08 | Neurodx, Llc | Compositions and methods relating to alzheimer’s disease |
| WO2007002285A2 (en) * | 2005-06-21 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Methods for treating neurological and psychiatric conditions |
| JP4176749B2 (ja) | 2005-07-29 | 2008-11-05 | 学校法人帝京大学 | 疾病検査法 |
| KR20080049821A (ko) | 2005-09-12 | 2008-06-04 | 페노미넘 디스커버리스 인코포레이티드 | 비타민 e-관련 대사산물의 측정에 의한 결장암 및난소암의 진단방법 |
| EP1932164B1 (en) | 2005-09-15 | 2013-04-24 | Phenomenome Discoveries Inc. | Method and apparatus for fourier transform ion cyclotron resonance mass spectrometry |
| KR20080104350A (ko) | 2006-02-28 | 2008-12-02 | 페노미넘 디스커버리스 인코포레이티드 | 치매 및 다른 신경 장애의 진단을 위한 방법 |
| EP2644588A3 (en) | 2006-05-26 | 2013-12-25 | Phenomenome Discoveries Inc. | Biomarkers for diagnosing multiple sclerosis, and methods thereof |
| JPWO2008093709A1 (ja) * | 2007-01-30 | 2010-05-20 | 株式会社プロジェクト・エム | アミロイド蛋白質の凝集抑制および分解促進によりアミロイドーシスと関連する疾患を予防または治療するための組成物 |
| EP2620147B1 (en) | 2007-02-08 | 2020-06-03 | Med-Life Discoveries LP | Compounds for lowering cholesterol |
| US8026099B2 (en) | 2007-07-26 | 2011-09-27 | Washington University | Lipid profile as a biomarker for early detection of neurological disorders |
-
2007
- 2007-08-27 EP EP13160192.4A patent/EP2620147B1/en active Active
- 2007-08-27 JP JP2009548551A patent/JP5470050B2/ja active Active
- 2007-08-27 WO PCT/CA2007/001472 patent/WO2008095275A1/en not_active Ceased
- 2007-08-27 EP EP07800499.1A patent/EP2117527B1/en active Active
- 2007-08-27 US US12/090,342 patent/US9034923B2/en active Active
- 2007-08-27 CA CA2695167A patent/CA2695167C/en active Active
- 2007-08-27 CA CA2620274A patent/CA2620274C/en active Active
- 2007-08-27 AU AU2007346587A patent/AU2007346587C1/en active Active
- 2007-08-27 SG SG2011053717A patent/SG173418A1/en unknown
-
2009
- 2009-07-23 IL IL200029A patent/IL200029A0/en unknown
-
2012
- 2012-06-18 US US13/526,197 patent/US8993623B2/en active Active
-
2015
- 2015-03-19 US US14/663,440 patent/US20160015673A1/en not_active Abandoned
- 2015-03-31 US US14/674,705 patent/US9517222B2/en active Active
-
2016
- 2016-11-11 US US15/349,831 patent/US10123989B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL200029A0 (en) | 2010-04-15 |
| US20170056363A1 (en) | 2017-03-02 |
| US9034923B2 (en) | 2015-05-19 |
| US20150306057A1 (en) | 2015-10-29 |
| AU2007346587A1 (en) | 2008-08-14 |
| AU2007346587C1 (en) | 2015-01-22 |
| EP2117527A4 (en) | 2012-09-12 |
| SG173418A1 (en) | 2011-08-29 |
| CA2620274C (en) | 2011-10-04 |
| EP2117527B1 (en) | 2020-06-17 |
| US10123989B2 (en) | 2018-11-13 |
| US20120129934A1 (en) | 2012-05-24 |
| US8993623B2 (en) | 2015-03-31 |
| JP2010518029A (ja) | 2010-05-27 |
| AU2007346587B2 (en) | 2014-03-27 |
| WO2008095275A1 (en) | 2008-08-14 |
| US9517222B2 (en) | 2016-12-13 |
| EP2620147A3 (en) | 2013-10-02 |
| CA2695167C (en) | 2011-11-01 |
| CA2695167A1 (en) | 2008-06-20 |
| US20130046016A1 (en) | 2013-02-21 |
| EP2620147B1 (en) | 2020-06-03 |
| EP2620147A2 (en) | 2013-07-31 |
| US20160015673A1 (en) | 2016-01-21 |
| EP2117527A1 (en) | 2009-11-18 |
| CA2620274A1 (en) | 2008-06-20 |
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