JP5416327B2 - タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 - Google Patents
タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 Download PDFInfo
- Publication number
- JP5416327B2 JP5416327B2 JP2004500859A JP2004500859A JP5416327B2 JP 5416327 B2 JP5416327 B2 JP 5416327B2 JP 2004500859 A JP2004500859 A JP 2004500859A JP 2004500859 A JP2004500859 A JP 2004500859A JP 5416327 B2 JP5416327 B2 JP 5416327B2
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- Prior art keywords
- antitumor agent
- cancer
- taxane
- agent
- taxane antitumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/135,975 US8710095B2 (en) | 2002-04-30 | 2002-04-30 | Drugs for prophylaxis or mitigation of taxane-induced neurotoxicity |
| US10/135,975 | 2002-04-30 | ||
| PCT/US2003/013518 WO2003092675A1 (en) | 2002-04-30 | 2003-04-29 | Drugs for mitigating taxane-induced neurotoxicity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011089619A Division JP2011140521A (ja) | 2002-04-30 | 2011-04-13 | タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005525409A JP2005525409A (ja) | 2005-08-25 |
| JP2005525409A5 JP2005525409A5 (enExample) | 2008-08-21 |
| JP5416327B2 true JP5416327B2 (ja) | 2014-02-12 |
Family
ID=29249584
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004500859A Expired - Fee Related JP5416327B2 (ja) | 2002-04-30 | 2003-04-29 | タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 |
| JP2011089619A Pending JP2011140521A (ja) | 2002-04-30 | 2011-04-13 | タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011089619A Pending JP2011140521A (ja) | 2002-04-30 | 2011-04-13 | タキサンにより惹起される神経毒性を予防又は軽減するための薬剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8710095B2 (enExample) |
| EP (1) | EP1503748B1 (enExample) |
| JP (2) | JP5416327B2 (enExample) |
| AT (1) | ATE554753T1 (enExample) |
| AU (1) | AU2003225253B2 (enExample) |
| CA (1) | CA2483857A1 (enExample) |
| ES (1) | ES2381968T3 (enExample) |
| WO (1) | WO2003092675A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8710095B2 (en) * | 2002-04-30 | 2014-04-29 | Bionumerik Pharmaceuticals, Inc. | Drugs for prophylaxis or mitigation of taxane-induced neurotoxicity |
| US20090111735A1 (en) * | 2004-05-12 | 2009-04-30 | Bionumerik Pharmaceuticals, Inc. | Compounds and methods for reducing undesired toxicity of chemotherapeutic agents |
| WO2007070599A2 (en) * | 2005-12-13 | 2007-06-21 | Bionumerik Pharmaceuticals, Inc. | Chemoprotective methods and compositions |
| WO2007109184A2 (en) * | 2006-03-16 | 2007-09-27 | Bionumerik Pharmaceuticals, Inc. | Anti-cancer activity augmentation compounds and formulations and methods of use thereof |
| EP2191836B1 (en) * | 2007-08-31 | 2012-05-23 | Kyushu University, National University Corporation | Prophylactic or alleviating agent for peripheral nerve disorder induced by anti-cancer agent |
| JP5696266B2 (ja) | 2007-11-20 | 2015-04-08 | ランケナー インスティテュート フォー メディカル リサーチ | ジスルフィド化学療法剤およびその使用方法 |
| WO2009113984A1 (en) * | 2008-03-14 | 2009-09-17 | Bionumerik Pharmaceuticals, Inc. | Chemoprotective methods and compositions |
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| AU3140093A (en) * | 1991-11-22 | 1993-06-15 | University Of Mississippi, The | Synthesis and optical resolution of the taxol side chain and related compounds |
| FR2722987B1 (fr) * | 1994-07-29 | 1997-05-16 | Synthelabo | Utilisation de l'eliprodil et de ses enantiomeres pour la preparation de medicaments utiles dans la prevention des neuropathiesinduites par des agentsanticancereux |
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| DE19617802A1 (de) * | 1996-05-03 | 1997-11-06 | Basf Ag | Verfahren zur heterogen katalysierten Herstellung von Hydroxyalkyl-substituierten Aminoalkinen |
| US6037336A (en) * | 1996-09-23 | 2000-03-14 | Bionumerik Pharmaceuticals, Inc. | Reducing toxic effects of carboplatin using dithioethers |
| CA2263166C (en) | 1996-09-23 | 2006-12-12 | Bionumerik Pharmaceuticals, Inc. | Reducing toxic effects of carboplatin using dithioethers |
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| US6251881B1 (en) | 1999-10-21 | 2001-06-26 | Frederick H. Hausheer | Method of treating diabetic angiopathy |
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- 2003-04-29 EP EP03721972A patent/EP1503748B1/en not_active Expired - Lifetime
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- 2011-04-13 JP JP2011089619A patent/JP2011140521A/ja active Pending
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| US8710095B2 (en) | 2014-04-29 |
| WO2003092675A1 (en) | 2003-11-13 |
| JP2011140521A (ja) | 2011-07-21 |
| CA2483857A1 (en) | 2003-11-13 |
| EP1503748A1 (en) | 2005-02-09 |
| ATE554753T1 (de) | 2012-05-15 |
| AU2003225253A1 (en) | 2003-11-17 |
| US20030203960A1 (en) | 2003-10-30 |
| JP2005525409A (ja) | 2005-08-25 |
| AU2003225253B2 (en) | 2008-09-04 |
| EP1503748A4 (en) | 2009-10-21 |
| ES2381968T3 (es) | 2012-06-04 |
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