JP5404021B2 - 時刻同期式血中グルコースシステム - Google Patents
時刻同期式血中グルコースシステム Download PDFInfo
- Publication number
- JP5404021B2 JP5404021B2 JP2008322544A JP2008322544A JP5404021B2 JP 5404021 B2 JP5404021 B2 JP 5404021B2 JP 2008322544 A JP2008322544 A JP 2008322544A JP 2008322544 A JP2008322544 A JP 2008322544A JP 5404021 B2 JP5404021 B2 JP 5404021B2
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- time
- blood glucose
- data
- time value
- data set
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008280 blood Substances 0.000 title claims description 171
- 210000004369 blood Anatomy 0.000 title claims description 171
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims description 168
- 239000008103 glucose Substances 0.000 title claims description 168
- 230000001360 synchronised effect Effects 0.000 title claims description 10
- 238000012545 processing Methods 0.000 claims description 111
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 79
- 230000005540 biological transmission Effects 0.000 claims description 41
- 102000004877 Insulin Human genes 0.000 claims description 40
- 108090001061 Insulin Proteins 0.000 claims description 40
- 229940125396 insulin Drugs 0.000 claims description 40
- 238000005259 measurement Methods 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 31
- 238000004458 analytical method Methods 0.000 claims description 27
- 238000003860 storage Methods 0.000 claims description 15
- 208000018914 glucose metabolism disease Diseases 0.000 claims description 14
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- 238000004891 communication Methods 0.000 description 15
- 238000001802 infusion Methods 0.000 description 14
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- 230000000875 corresponding effect Effects 0.000 description 8
- 206010012601 diabetes mellitus Diseases 0.000 description 8
- 238000011156 evaluation Methods 0.000 description 8
- 229940127560 insulin pen Drugs 0.000 description 8
- 230000002123 temporal effect Effects 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 238000012937 correction Methods 0.000 description 4
- 239000010453 quartz Substances 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 description 3
- 238000011157 data evaluation Methods 0.000 description 2
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- 238000013461 design Methods 0.000 description 1
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- 238000006073 displacement reaction Methods 0.000 description 1
- 230000004153 glucose metabolism Effects 0.000 description 1
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- 239000007929 subcutaneous injection Substances 0.000 description 1
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Images
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Business, Economics & Management (AREA)
- Business, Economics & Management (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Computer Networks & Wireless Communication (AREA)
- Pharmacology & Pharmacy (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07024884.4A EP2073135B1 (de) | 2007-12-21 | 2007-12-21 | Blutglukosesystem mit Zeitsynchronisation |
| EP07024884.4 | 2007-12-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009183692A JP2009183692A (ja) | 2009-08-20 |
| JP2009183692A5 JP2009183692A5 (enExample) | 2013-06-27 |
| JP5404021B2 true JP5404021B2 (ja) | 2014-01-29 |
Family
ID=39217876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008322544A Active JP5404021B2 (ja) | 2007-12-21 | 2008-12-18 | 時刻同期式血中グルコースシステム |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10169540B2 (enExample) |
| EP (1) | EP2073135B1 (enExample) |
| JP (1) | JP5404021B2 (enExample) |
| CN (1) | CN101461969B (enExample) |
| CA (1) | CA2645944C (enExample) |
| DK (1) | DK2073135T3 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100165795A1 (en) * | 2008-12-30 | 2010-07-01 | Lifescan Scotland Ltd. | Medical device with automatic time and date correction |
| ES2683700T3 (es) | 2009-02-27 | 2018-09-27 | Lifescan, Inc. | Sistemas y métodos de gestión de administración de fármacos |
| EP2306352B1 (en) * | 2009-09-25 | 2013-01-09 | Roche Diagnostics GmbH | Diabetes therapy device enabling shifting of parameter profiles |
| US8092428B2 (en) | 2009-12-23 | 2012-01-10 | Roche Diagnostics Operations, Inc. | Methods and systems for adjusting an insulin delivery profile of an insulin pump |
| JP5304674B2 (ja) * | 2010-02-02 | 2013-10-02 | 富士通株式会社 | データ変換装置、データ変換方法及びプログラム |
| US10201296B2 (en) | 2010-11-11 | 2019-02-12 | Ascensia Diabetes Care Holdings Ag | Apparatus, systems, and methods adapted to transmit analyte data having common electronic architecture |
| CN103443798B (zh) | 2011-03-30 | 2017-05-10 | 诺沃—诺迪斯克有限公司 | 用于优化一段时间内的患者的药物给药方案的系统 |
| KR101182733B1 (ko) * | 2011-04-13 | 2012-09-13 | 주식회사 필로시스 | 진단스트립 분석장치의 시간동기화 방법 |
| KR101367261B1 (ko) | 2011-11-11 | 2014-03-14 | 주식회사 아이센스 | 시간 동기화 방식이 적용된 무선 통신 모듈을 장착한 혈당 측정기 시스템 |
| CN105530916B (zh) * | 2013-07-11 | 2020-04-07 | 艾利斯达医药品公司 | 与间水杨酸形成的烟碱盐 |
| EP3049132B1 (en) | 2013-09-26 | 2020-08-19 | Companion Medical, Inc. | System for administering a medicament |
| US20150106124A1 (en) * | 2013-10-15 | 2015-04-16 | Medtronic, Inc | Date and time accuracy testing patient data transferred from a remote device |
| CN105813545A (zh) * | 2013-11-22 | 2016-07-27 | Mc10股份有限公司 | 用于感测和分析心搏的适形传感器系统 |
| CN114582482A (zh) * | 2014-01-10 | 2022-06-03 | 安晟信医疗科技控股公司 | 终端用户医疗设备、用于同步该设备的方法和血糖仪 |
| CN106461638A (zh) | 2014-04-11 | 2017-02-22 | 安晟信医疗科技控股公司 | 电池供电式生物传感器仪表的无线发射器适配器及设置方法 |
| US9629901B2 (en) * | 2014-07-01 | 2017-04-25 | Bigfoot Biomedical, Inc. | Glucagon administration system and methods |
| JP6824874B2 (ja) | 2014-07-07 | 2021-02-03 | アセンシア・ディアベティス・ケア・ホールディングス・アーゲー | 改善された低エネルギーデータ通信のための方法および装置 |
| WO2016007935A2 (en) * | 2014-07-10 | 2016-01-14 | Companion Medical, Inc. | Medicine administering system including injection pen and companion device |
| JP2017525451A (ja) * | 2014-08-01 | 2017-09-07 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 連続的なグルコースのモニタリングをする投入装置 |
| HK1250273A1 (zh) | 2015-04-29 | 2018-12-07 | 安晟信医疗科技控股公司 | 基於位置的无线糖尿病管理系统、方法和设备 |
| CN105342640B (zh) * | 2015-11-26 | 2018-08-21 | 深圳市理邦精密仪器股份有限公司 | 无线探头超声波信号发射同步校准方法、装置及监护设备 |
| WO2017132577A1 (en) | 2016-01-29 | 2017-08-03 | Companion Medical, Inc. | Automatic medication delivery tracking |
| US9974903B1 (en) | 2016-05-02 | 2018-05-22 | Dexcom, Inc. | System and method for providing alerts optimized for a user |
| TWI644187B (zh) * | 2016-05-06 | 2018-12-11 | 泰博科技股份有限公司 | 生理數據校時方法、系統、非暫態電腦可讀取媒體及電腦程式產品 |
| US10816937B2 (en) | 2016-07-12 | 2020-10-27 | Stryker Corporation | Patient support apparatuses with clocks |
| CN107970505B (zh) * | 2016-10-24 | 2020-11-03 | 田中枢 | 一种便携式胰岛素雾化给药装置 |
| US10956538B2 (en) * | 2016-12-03 | 2021-03-23 | Verily Life Sciences Llc | Low-power systems and methods for determining measurement times of values obtained by a measuring device |
| EP3576815A4 (en) * | 2017-02-03 | 2020-11-18 | University Of Virginia Patent Foundation | METHOD, SYSTEM, AND COMPUTER READABLE MEDIA FOR CONTROLLING INSULIN DISTRIBUTION USING RETROSPECTIVE VIRTUAL BASAL RATES |
| US11484657B2 (en) | 2017-06-09 | 2022-11-01 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods |
| US20190000360A1 (en) * | 2017-06-29 | 2019-01-03 | Abbott Diabetes Care Inc. | Systems, devices, and methods for establishing and/or maintaining synchronization between entities in an analyte monitoring environment |
| WO2019075352A1 (en) | 2017-10-12 | 2019-04-18 | Companion Medical, Inc. | INTELLIGENT DRUG DELIVERY SYSTEMS AND METHODS OF RECOMMENDATION AND DOSE MANAGEMENT |
| US11116899B2 (en) | 2017-12-12 | 2021-09-14 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems and devices |
| US11083852B2 (en) | 2017-12-12 | 2021-08-10 | Bigfoot Biomedical, Inc. | Insulin injection assistance systems, methods, and devices |
| US11197964B2 (en) | 2017-12-12 | 2021-12-14 | Bigfoot Biomedical, Inc. | Pen cap for medication injection pen having temperature sensor |
| US11464459B2 (en) | 2017-12-12 | 2022-10-11 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems including flash glucose monitor |
| US10987464B2 (en) | 2017-12-12 | 2021-04-27 | Bigfoot Biomedical, Inc. | Pen cap for insulin injection pens and associated methods and systems |
| EP3724888A1 (en) | 2017-12-12 | 2020-10-21 | Bigfoot Biomedical, Inc. | Therapy management systems, methods, and devices |
| US11077243B2 (en) | 2017-12-12 | 2021-08-03 | Bigfoot Biomedical, Inc. | Devices, systems, and methods for estimating active medication from injections |
| US11723560B2 (en) | 2018-02-09 | 2023-08-15 | Dexcom, Inc. | System and method for decision support |
| JP7587344B2 (ja) | 2018-04-12 | 2024-11-20 | レーヴェンシュタイン メディカル テクノロジー エス.アー. | データ伝送をするためのシステム |
| US11664107B2 (en) | 2018-05-08 | 2023-05-30 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods using a prescription-regulated software application |
| US10898653B2 (en) | 2018-05-08 | 2021-01-26 | Companion Medical, Inc. | Intelligent medication delivery systems and methods for dose setting and dispensing monitoring |
| USD893020S1 (en) | 2018-05-11 | 2020-08-11 | Companion Medical, Inc. | Injection pen |
| USD892819S1 (en) | 2018-06-20 | 2020-08-11 | Companion Medical, Inc. | Display screen with graphical user interface |
| US11587663B2 (en) | 2018-06-20 | 2023-02-21 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods for medicine dose calculation and reporting |
| US12205699B1 (en) | 2018-10-30 | 2025-01-21 | Bigfoot Biomedical, Inc. | Method of pairing therapy devices using shared secrets, and related systems, methods and devices |
| US11948671B2 (en) | 2019-04-11 | 2024-04-02 | Medtronic Minimed, Inc. | Intelligent accessories for medicine dispensing device |
| US11701473B2 (en) | 2021-06-23 | 2023-07-18 | Medtronic Minimed, Inc. | Reusable injection pens |
| CN114093489B (zh) * | 2021-09-29 | 2022-09-30 | 北京华益精点生物技术有限公司 | 非智能血糖仪的血糖检测时间的确认方法及相关设备 |
| CN114166913B (zh) * | 2022-02-10 | 2022-05-27 | 苏州百孝医疗科技有限公司 | 自动校准方法和装置、监测分析物浓度水平的系统 |
| CN115049037A (zh) * | 2022-06-20 | 2022-09-13 | 江苏讯达电气有限公司 | 一种货运列车装载货物计数装置及其计数方法 |
| EP4350703A1 (en) * | 2022-10-07 | 2024-04-10 | Sanofi | Method, apparatus and devices for determining an absolute time of one or more recorded dose events performed with a medical device |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6145733A (ja) | 1984-08-09 | 1986-03-05 | 株式会社 建部青州堂 | 携帯用心電図記憶装置 |
| US5536249A (en) * | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
| WO1999002210A1 (en) * | 1997-07-11 | 1999-01-21 | Novo Nordisk A/S | An apparatus for the registration of the setting of a medical device |
| DE19733445A1 (de) | 1997-08-02 | 1999-02-18 | Boehringer Mannheim Gmbh | Analysesystem umfassend ein Analysegerät sowie eine DV-Einheit |
| US5921938A (en) * | 1997-10-09 | 1999-07-13 | Physio-Control Manufacturing Corporation | System and method for adjusting time associated with medical event data |
| US6001082A (en) * | 1998-02-20 | 1999-12-14 | Becton Dickinson And Company | Medication delivery pen with an integral magnifying pocket clip |
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| CA2343796C (en) | 1998-09-30 | 2009-04-21 | Luis J. Malave | Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like |
| US6540672B1 (en) * | 1998-12-09 | 2003-04-01 | Novo Nordisk A/S | Medical system and a method of controlling the system for use by a patient for medical self treatment |
| DE29904864U1 (de) * | 1999-03-17 | 2000-08-03 | B. Braun Melsungen Ag, 34212 Melsungen | Injektionsvorrichtung mit einem Pen |
| US6277099B1 (en) * | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
| US6585698B1 (en) * | 1999-11-01 | 2003-07-01 | Becton, Dickinson & Company | Electronic medical delivery pen having a multifunction actuator |
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2007
- 2007-12-21 DK DK07024884.4T patent/DK2073135T3/da active
- 2007-12-21 EP EP07024884.4A patent/EP2073135B1/de active Active
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- 2008-12-08 CA CA2645944A patent/CA2645944C/en active Active
- 2008-12-18 JP JP2008322544A patent/JP5404021B2/ja active Active
- 2008-12-19 US US12/339,968 patent/US10169540B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2073135B1 (de) | 2018-10-03 |
| DK2073135T3 (da) | 2019-01-02 |
| EP2073135A1 (de) | 2009-06-24 |
| CN101461969A (zh) | 2009-06-24 |
| HK1129612A1 (en) | 2009-12-04 |
| CN101461969B (zh) | 2012-04-04 |
| CA2645944A1 (en) | 2009-06-21 |
| US10169540B2 (en) | 2019-01-01 |
| US20090163793A1 (en) | 2009-06-25 |
| JP2009183692A (ja) | 2009-08-20 |
| CA2645944C (en) | 2013-05-14 |
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