JP5373597B2 - アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質 - Google Patents

アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質 Download PDF

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JP5373597B2
JP5373597B2 JP2009504853A JP2009504853A JP5373597B2 JP 5373597 B2 JP5373597 B2 JP 5373597B2 JP 2009504853 A JP2009504853 A JP 2009504853A JP 2009504853 A JP2009504853 A JP 2009504853A JP 5373597 B2 JP5373597 B2 JP 5373597B2
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chimeric protein
protein
allergen
chimeric
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JP2009533046A (ja
JP2009533046A5 (OSRAM
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オルテガ,ユアン アンドレス アスツリアス
ガラテ,アルベルト マルチネズ
リオヤ,ロベルト ゴンザレス
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ビアル インダストリアル ファーマキューティカ,エス.エー.
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • A61K39/36Allergens from pollen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • C07K14/625Extraction from natural sources
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2009504853A 2006-04-12 2007-04-11 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質 Expired - Fee Related JP5373597B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200600955 2006-04-12
ES200600955A ES2307381B1 (es) 2006-04-12 2006-04-12 Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
PCT/IB2007/001025 WO2007116316A1 (en) 2006-04-12 2007-04-11 Hypoallergenic chimeric proteins belonging to the lipid transfer family of parietaria judaica for use in the treatment of allergies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013141864A Division JP6148088B2 (ja) 2006-04-12 2013-07-05 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質

Publications (3)

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JP2009533046A JP2009533046A (ja) 2009-09-17
JP2009533046A5 JP2009533046A5 (OSRAM) 2009-11-26
JP5373597B2 true JP5373597B2 (ja) 2013-12-18

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Family Applications (3)

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JP2009504853A Expired - Fee Related JP5373597B2 (ja) 2006-04-12 2007-04-11 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質
JP2013141864A Expired - Fee Related JP6148088B2 (ja) 2006-04-12 2013-07-05 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質
JP2016015356A Pending JP2016104796A (ja) 2006-04-12 2016-01-29 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2013141864A Expired - Fee Related JP6148088B2 (ja) 2006-04-12 2013-07-05 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質
JP2016015356A Pending JP2016104796A (ja) 2006-04-12 2016-01-29 アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質

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Country Link
US (2) US8697083B2 (OSRAM)
EP (3) EP2392592B1 (OSRAM)
JP (3) JP5373597B2 (OSRAM)
CN (2) CN103059140B (OSRAM)
BR (1) BRPI0710649A2 (OSRAM)
CA (1) CA2646900C (OSRAM)
ES (2) ES2307381B1 (OSRAM)
MX (1) MX2008013050A (OSRAM)
PT (1) PT2007798E (OSRAM)
WO (1) WO2007116316A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016104796A (ja) * 2006-04-12 2016-06-09 ビアル インダストリアル ファーマキューティカ,エス.エー. アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1395735B1 (it) * 2009-08-04 2012-10-19 Lofarma Spa Proteina ibrida ipoallergenica e suoi usi
RU2470298C2 (ru) * 2011-04-01 2012-12-20 Федеральное бюджетное учреждение науки "Уфимский научно-исследовательский институт медицины труда и экологии человека" (ФБУН "Уфимский НИИ медицины труда и экологии человека") Способ ранней (донозологической) диагностики развития сенсибилизации к аллергенам воздуха рабочей зоны птицеводческого комплекса

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10037759A1 (de) 2000-08-03 2002-07-04 Gruenenthal Gmbh Screeningverfahren
IT1317905B1 (it) 2000-09-11 2003-07-15 Consiglio Nazionale Ricerche Varianti di allergeni ns-ltps, loro usi e composizioni che lecomprendono.
IT1318690B1 (it) 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti dell'allergene maggiore par j 2 di parietaria judaica.
US20030175312A1 (en) * 2000-11-16 2003-09-18 Alk-Abello A/S Novel mutant allergens
EP1221317A1 (en) * 2000-12-28 2002-07-10 SHAN-Beteiligungsgesellschaft m.b.H. Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins
WO2002088317A2 (en) * 2001-05-01 2002-11-07 The Regents Of The University Of California Fusion molecules and methods for treatment of immune diseases
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
ATE307141T1 (de) * 2003-01-21 2005-11-15 Biomay Prod & Handel Verfahren zur vorbereitung von hypoallergenen mosaikproteine
ITRM20030247A1 (it) * 2003-05-20 2004-11-21 Bonura Angela Varianti ipoallergeniche degli allergeni maggiori
ITRM20040103A1 (it) * 2004-02-27 2004-05-27 Consiglio Nazionale Ricerche Proteine di fusione comprendenti allergeni della famiglia delle ns-ltps, loro usi e composizioni farmaceutiche che le comprendono.
AT501101B1 (de) * 2004-12-02 2008-01-15 Biomay Ag Protein-allergen-derivat
ES2307381B1 (es) * 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016104796A (ja) * 2006-04-12 2016-06-09 ビアル インダストリアル ファーマキューティカ,エス.エー. アレルギー治療に用いるカベイラクサ(Parietariajudaica)の脂質輸送タンパク質ファミリーに属する低アレルギー誘導性のキメラタンパク質

Also Published As

Publication number Publication date
CA2646900C (en) 2016-06-14
JP2009533046A (ja) 2009-09-17
ES2307381B1 (es) 2009-10-23
ES2550705T3 (es) 2015-11-11
BRPI0710649A2 (pt) 2011-08-23
MX2008013050A (es) 2009-01-14
EP2392592A1 (en) 2011-12-07
EP2007798A1 (en) 2008-12-31
CN103059140A (zh) 2013-04-24
ES2307381A2 (es) 2008-11-16
ES2307381R (es) 2008-12-01
CN103059140B (zh) 2016-09-28
EP2363409A1 (en) 2011-09-07
CN101421296B (zh) 2013-01-02
PT2007798E (pt) 2015-11-13
CA2646900A1 (en) 2007-10-18
US20140286972A1 (en) 2014-09-25
US9522939B2 (en) 2016-12-20
JP6148088B2 (ja) 2017-06-14
US20090304727A1 (en) 2009-12-10
US8697083B2 (en) 2014-04-15
JP2013233149A (ja) 2013-11-21
EP2007798B1 (en) 2015-09-30
CN101421296A (zh) 2009-04-29
JP2016104796A (ja) 2016-06-09
EP2392592B1 (en) 2016-12-14
WO2007116316A1 (en) 2007-10-18

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