JP5369118B2 - バイオマーカーplgfを用いてアテローム性動脈硬化負荷を決定する手段及び方法 - Google Patents

バイオマーカーplgfを用いてアテローム性動脈硬化負荷を決定する手段及び方法 Download PDF

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Publication number
JP5369118B2
JP5369118B2 JP2010546298A JP2010546298A JP5369118B2 JP 5369118 B2 JP5369118 B2 JP 5369118B2 JP 2010546298 A JP2010546298 A JP 2010546298A JP 2010546298 A JP2010546298 A JP 2010546298A JP 5369118 B2 JP5369118 B2 JP 5369118B2
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Japan
Prior art keywords
plgf
subject
load
polypeptide
amount
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JP2010546298A
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Japanese (ja)
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JP2011511944A (ja
JP2011511944A5 (enExample
Inventor
ヘス,ゲオルグ
ホーシュ,アンドレア
ツネック,ディエトマー
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/515Angiogenesic factors; Angiogenin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/323Arteriosclerosis, Stenosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010546298A 2008-02-13 2009-02-09 バイオマーカーplgfを用いてアテローム性動脈硬化負荷を決定する手段及び方法 Expired - Fee Related JP5369118B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08151376A EP2090891A1 (en) 2008-02-13 2008-02-13 Means and methods for determining the atherosclerotic load using the biomarker PLGF
EP08151376.4 2008-02-13
PCT/EP2009/051420 WO2009101037A1 (en) 2008-02-13 2009-02-09 Means and methods for determining the atherosclerosis load using the biomarker plgf

Publications (3)

Publication Number Publication Date
JP2011511944A JP2011511944A (ja) 2011-04-14
JP2011511944A5 JP2011511944A5 (enExample) 2011-07-07
JP5369118B2 true JP5369118B2 (ja) 2013-12-18

Family

ID=39183148

Family Applications (1)

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JP2010546298A Expired - Fee Related JP5369118B2 (ja) 2008-02-13 2009-02-09 バイオマーカーplgfを用いてアテローム性動脈硬化負荷を決定する手段及び方法

Country Status (4)

Country Link
US (1) US20100273268A1 (enExample)
EP (2) EP2090891A1 (enExample)
JP (1) JP5369118B2 (enExample)
WO (1) WO2009101037A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5717108B2 (ja) * 2009-09-17 2015-05-13 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 左心室肥大のためのマルチマーカーパネル
EP2367006A1 (en) 2010-08-24 2011-09-21 Roche Diagnostics GmbH PLGF-based means and methods for diagnosing cardiac causes in acute inflammation
WO2012066140A1 (en) * 2010-11-19 2012-05-24 Roche Diagnostics Gmbh Method for monitoring physical training in healthy and diseased individuals
CA2913676A1 (en) * 2013-05-31 2014-12-04 Cobiores Nv Human plgf-2 for the prevention or treatment of heart failure

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US20050154407A1 (en) * 2000-12-20 2005-07-14 Fox Hollow Technologies, Inc. Method of evaluating drug efficacy for treating atherosclerosis
DE50309809D1 (de) * 2002-11-16 2008-06-19 Dade Behring Marburg Gmbh Scd40l, papp-a und plazentaler-wachstumsfaktor (pigf) als biochemische markerkombinationen bei kardiovaskulären erkrankungen
US20050272098A1 (en) * 2004-04-23 2005-12-08 Tramontano Anthony F Quantitation of endothelial microparticles
DE602005001299T2 (de) * 2004-07-07 2008-02-07 Roche Diagnostics Gmbh Kombinationen von Markern zum Nachweis von typ 1 und 2 Diabetes
DE102004051847B4 (de) * 2004-10-25 2008-09-18 Dade Behring Marburg Gmbh Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen

Also Published As

Publication number Publication date
WO2009101037A1 (en) 2009-08-20
JP2011511944A (ja) 2011-04-14
EP2252894A1 (en) 2010-11-24
US20100273268A1 (en) 2010-10-28
EP2090891A1 (en) 2009-08-19

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