JP5295073B2 - Health supplements - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide health supplement food capable of continuously preventing discomfort taste of arginine from the moment of oral ingestion. <P>SOLUTION: Based on the total mass of health supplement food, arginine is contained in 1 to 80 mass%, d-ribose in 0.05 to 5 mass%, sorbitol in 0.2 to 20 mass%, malic acid in 0.5 to 50 mass%, aspartame in 0.1 to 10 mass% and further blueberry fruit juice powder in 0.05 to 5 mass%. <P>COPYRIGHT: (C)2011,JPO&amp;INPIT

Description

  The present invention relates to a health supplement containing arginine, and in particular, to a health supplement that prevents the unpleasant taste of arginine that is continued immediately after ingestion.

  Conventionally, tablets, granules, powders, pills, liquids, pastes, gels intended to replenish specific nutritional ingredients that tend to be deficient in daily life or food materials with health maintenance / promotion effects Various forms of health supplements (so-called supplements) such as pharmaceuticals and jelly-like agents are known. Among them, nutritional supplements containing amino acids as nutritional components are known to exert excellent effects on health maintenance, etc., and health supplements containing amino acids are diet, shape-up, power-up, It is widely used in a wide range of generations (for example, athletes, sports enthusiasts, OLs, office workers, young generations to seniors) for the purpose of improving stamina and whitening.

  Among amino acids, arginine, which is a raw material for proteins, promotes the secretion of growth hormone (for example, increased muscle, diet, beautiful skin, rejuvenation, etc.), improves liver function, immunity, protects blood vessels, and protects blood flow It is known to play an important role in the structure of the body, such as improvement, and recently, attention is being paid to health supplements containing arginine.

  However, arginine has a peculiar and extremely unpleasant taste (puffy taste, bitter taste, etc.), and health supplements containing arginine are unpleasant in the tongue and oral cavity for a while after ingestion. A fresh taste will remain.

  On the other hand, under such circumstances, various studies have been made on so-called “masking” technology for reducing discomfort and discomfort when ingesting foods and medicines having undesirable odors and tastes, for example, A so-called “masking” technique is known in which unpleasant tastes and aromas of foods and pharmaceuticals are hidden by adding sugars, organic acids, fragrances, and the like. As an example, Patent Document 1 discloses a dietary supplement in which arginine and L-ascorbic acid are mixed as a technique for masking the arginine taste using a “masking” technique.

Japanese Patent No. 3574925

  However, as described above, since arginine has an unpleasant taste in the tongue and oral cavity for a while after ingestion from the moment of ingestion, vitamin C is added to arginine as disclosed in Patent Document 1. Although only a certain amount of L-ascorbic acid is mixed, a certain masking effect can be exhibited at a predetermined stage, but it has not yet prevented the unpleasant taste of arginine from the moment of ingestion to the long term after ingestion. Is the current situation.

  The present invention has been made in view of such circumstances, and provides a health supplement that can prevent the unpleasant taste (eg, savory taste, bitter taste) of arginine from the moment of ingestion to the long term after ingestion. The main task is to do.

  The present invention for solving the above problems is a health supplement containing arginine, wherein 1 to 80% by mass of arginine and 0.05 to 5 of d-ribose with respect to the total mass of the health supplement. It contains 0.2 to 20% by mass of sorbitol, 0.5 to 50% by mass of malic acid, and 0.1 to 10% by mass of aspartame.

  Moreover, it is good also as containing further fruit juice powder in the ratio of 0.05-5 mass% with respect to the total mass of the said health supplement. The fruit juice powder may be blueberry fruit juice powder.

  ADVANTAGE OF THE INVENTION According to this invention, it becomes possible to provide the health supplement which can prevent the unpleasant taste (egg taste, bitter taste) of arginine from the moment of ingestion to the long term after ingestion.

It is a figure which shows the relationship between the masking effect of this invention, and time.

  The inventor firstly promoted the secretion of growth hormone from a plurality of amino acids, improved liver function and immunity, and protected arginine that plays an important role in the body's structure, such as protecting blood vessels and improving blood flow. It was adopted as an essential ingredient in the health supplement of the present invention. However, arginine has a peculiar unpleasant taste (gummy taste, bitter taste, etc.), and when arginine is included as a component of a health supplement, intake is avoided from the unpleasant taste. Become.

  Under such circumstances, the present inventor has conducted extensive studies. As a result, when a health supplement containing arginine is orally ingested, the unpleasant taste caused by arginine is not the taste of the moment when it is orally ingested (“pre-taste”). )), The taste that appears after a while since it was ingested (“aftertaste”), and the taste that is located between “foretime” and “aftertaste” and feels in the middle (“medium”) It has been found that it consists of three stages, each of which has a different and unpleasant taste. This is thought to be due to the fact that arginine stimulates multiple types of sensory organs of the tongue.

  Based on such knowledge, the inventor of the present application determines the unpleasant taste that is felt at each stage (for each “pre-taste”, “middle taste”, and “aftertaste”) for each stage (“pre-taste”, “ ”And“ aftertaste ”individually, each of which has the technical idea that the unpleasant taste of arginine can be completely prevented at all stages. A masking component capable of masking an unpleasant taste in “medium” and “aftertaste”) has been intensively studied and the present invention has been completed.

  The present invention completed on the basis of such a technical idea, arginine 1-80 mass%, d-ribose 0.05-5 mass%, sorbitol 0.2 -20% by mass, malic acid 0.5-50% by mass, and aspartame 0.1-10% by mass. Hereinafter, each component and the masking effect by containing each component will be specifically described with reference to FIG. FIG. 1 is a schematic diagram showing the relationship between the masking component and the masking effect. The vertical axis shows the masking effect, and the horizontal axis shows the passage of time from immediately after ingestion.

(Arginine)
Arginine is an essential component in the dietary supplement of the present invention, promotes the secretion of growth hormone, improves liver function and immunity, and plays an important role in the body's structure, such as protecting blood vessels and improving blood flow. It is an amino acid and is contained in a proportion of 1 to 80%, preferably 5 to 40% by mass with respect to the total mass of the health supplement of the present invention. In addition, when the content of arginine is more than 80% by mass of the total mass of the health supplement, it is difficult to prevent unpleasant taste even when each component described below is contained, When it is less than 1% by mass of the total mass, the desired effect by arginine cannot be exhibited.

(Masking component)
As described above, the health supplement containing arginine in the above-described ratio exhibits a unique and unpleasant taste of arginine at each stage (“pre-taste”, “medium”, “aftertaste”). Therefore, in the present invention, a masking component for masking a unique unpleasant taste caused by arginine in each stage (“pre-taste”, “middle taste”, “aftertaste”) is contained. Specifically, the health supplement of the present invention contains d-ribose and sorbitol as the masking component A, malic acid as the masking component B, and aspartame as the masking component C in a predetermined ratio described later.

(Masking component A)
Masking component A is composed of d-ribose and sorbitol. d-ribose is contained in a proportion of 0.05 to 5% by mass, preferably 0.3 to 1% by mass, based on the total mass of the health supplement, and sorbitol is 0.2% based on the total mass of the health supplement. It is contained in a proportion of ˜20% by mass, preferably 1 to 4% by mass.

  The d-ribose and sorbitol, which are masking components A, have the property that the sweetness spreads instantly when they are ingested, and the masking component A (d-ribose, sorbitol) is added in the above proportion to the total mass of the health supplement. By containing, as shown in FIG. 1, it becomes possible to completely mask the unpleasant “fore taste” due to arginine that is felt immediately after ingestion.

(Masking component B)
As shown in FIG. 1, by containing the masking component A, unpleasant “pre-taste” due to arginine can be masked, but as time passes (from “pre-taste” to “middle”). Gradually the masking effect decreases. Therefore, the health supplement of the present invention contains a masking component B for masking an unpleasant “content” due to arginine located at an intermediate time between the “fore taste” and the “after taste”.

  The masking component B is composed of malic acid and is contained in a proportion of 0.5 to 50% by mass, preferably 3 to 10% by mass, based on the total mass of the health supplement. Malic acid has a sour taste, and by adding the masking component B in the above proportion to the total mass of the health supplement, as shown in FIG. 1, an intermediate between “fore taste” and “after taste”. It becomes possible to mask the unpleasant “content” due to arginine located at the time.

(Masking component C)
Although the unpleasant “content” due to arginine can be masked by containing the masking component B, the masking effect gradually decreases, and the unpleasant taste (so-called “aftertaste”) that remains on the tongue for a while after ingestion, and the oral cavity It is not possible to prevent the lingering taste remaining inside. Therefore, the health supplement of the present invention contains a masking component C for masking an unpleasant “aftertaste” caused by arginine.

  The masking component C is composed of aspartame and is contained in a proportion of 0.1 to 10% by mass, preferably 0.5 to 2% by mass, based on the total mass of the health supplement. Aspartame is an alternative sweetener and has a low masking effect on the unpleasant `` fore taste '' and `` medium '' caused by arginine, but has a high masking effect on the unpleasant `` after taste '' caused by arginine. By containing the masking component C at a ratio of, as shown in FIG. 1, it is possible to mask the unpleasant taste that remains on the tongue for a while after ingestion and the taste that remains in the oral cavity.

  That is, according to the present invention, at least one of the masking component A, the masking component B, and the masking component C is masked at each stage (“pre-taste”, “middle”, “aftertaste”) immediately after ingestion. Since the effect is exhibited, the health supplement of the present invention can be ingested without feeling unpleasant taste due to arginine.

  There is no limitation on the form of the health supplement of the present invention. Examples of such forms include powders, granules, pills, liquids, pastes, gels, and jellys.

(Fruit juice powder)
Moreover, it is good also as making the health supplement food of this invention contain fruit juice powder further. The fruit juice powder plays a role of masking the unpleasant taste of arginine by imparting an overall mellow flavor to the health supplement of the present invention with its delicious “taste and aroma”.

  Although there is no limitation in particular about content of fruit juice powder, it is preferable to contain in the ratio of 0.05-5 mass% with respect to the total mass of a health supplement, and it contains in the ratio of 0.3-1 mass% More preferably.

  Also, there is no particular limitation on the fruit powder, blueberry fruit powder, acai fruit powder, acerola fruit powder, lemon fruit powder, strawberry fruit powder, orange fruit powder, apple fruit powder, grape fruit powder, melon fruit powder, etc. The fruit juice powder can be appropriately selected and used. Among these, blueberry juice powder has a high masking effect on the unpleasant taste of arginine, and therefore can be particularly suitably used as a fruit powder blended in the health supplement of the present invention.

(Other amino acids)
Further, the health supplement of the present invention may further contain other amino acids as necessary. Other amino acids include citrulline, which has an effect of improving blood flow, BCAA, which is the main amino acid that makes up muscles, the promotion of muscle protein synthesis, functions of digestive organs such as the stomach and small intestine, Glutamine has an effect on maintaining structure, proline has an effect on skin regeneration and fat burning, suppresses the increase of blood cholesterol level, prevents hypertension, stroke, and moisturizes / oxidizes, soothing the skin And glycine having an effect of keeping moisture. There is no limitation in particular about content of another amino acid, It can contain suitably in the range which does not prevent content of said arginine and a masking component.

(Vitamins)
Moreover, it is good also as making the health supplement of this invention contain functional components, such as nutritional components, such as vitamins, and an antioxidant component, as needed. Examples of vitamins include vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, pantothenic acid, folic acid, vitamin C, vitamin D, vitamin E, and the like. The content of vitamins is not particularly limited, and can be appropriately contained within a range that does not hinder the contents of the arginine and the masking component.

  Hereinafter, the present invention will be described in more detail with reference to examples and comparative examples. Hereinafter, unless otherwise specified,% is based on mass.

Example 1
Arginine: 30.0% by mass, d-ribose: 0.5% by mass, sorbitol: 2.0% by mass, malic acid: 6.0% by mass, aspartame: 1.2% by mass, balance: crystalline cellulose The health supplement of Example 1 was manufactured by blending each component. In addition, the form of the manufactured health supplement was powdery. (The same applies to the following Example 2 and Comparative Examples 1 to 5)

(Example 2)
Arginine: 30.0% by mass, d-ribose: 0.5% by mass, sorbitol: 2.0% by mass, malic acid: 6.0% by mass, aspartame: 1.2% by mass, blueberry juice powder: 0.5 The health supplement of Example 1 was produced by blending each component in the ratio of mass%, balance: crystalline cellulose.

(Comparative Example 1)
The health supplement of Comparative Example 1 was produced by blending each component in the ratio of arginine: 30.0% by mass, balance: crystalline cellulose.

(Comparative Example 2)
The health supplement of Comparative Example 2 was produced by blending each component in the proportions of arginine: 30.0% by mass, fragrance: 3.0% by mass, and balance: crystalline cellulose.

(Comparative Example 3)
The health supplement of Comparative Example 3 was produced by blending each component in the ratios of arginine: 30.0% by mass, d-ribose: 0.5% by mass, sorbitol: 2.0% by mass, and balance: crystalline cellulose.

(Comparative Example 4)
The health supplement of Comparative Example 4 was produced by blending each component in a ratio of arginine: 30.0% by mass, malic acid: 6.0% by mass, and the balance: crystalline cellulose.

(Comparative Example 5)
The health supplement of Comparative Example 5 was produced by blending each component in a ratio of arginine: 30.0% by mass, aspartame: 1.2% by mass, and the balance: crystalline cellulose.

(Sensory test)
A: “Pre-taste”, B: “Aftertaste”, C: “Harmony of pre-taste and aftertaste (content)”, and D when ingesting health supplements of Examples 1 and 2 and Comparative Examples 1-5 : About the whole finish, the sensory test by 12 tasters was performed, the score evaluation for every test item, and the investigation about the whole impression were conducted. Table 1 shows the evaluation results of the sensory test. The sensory test was performed under the following conditions, and the average value of the scores is shown in the table. The right column in the table shows representative comments from the tasters.

A: Evaluation condition of “pre-taste”, B: “aftertaste” 1 point: Bitterness remains and cannot be used.
2 points ... The bitterness remains, and its use is questionable.
3 points: The bitterness remains slightly, but is in an acceptable range.
4 points ... Slight bitterness remains.
5 points: No bitterness remains.

C: Evaluation condition of “harmony of fore and after taste” 1 point: Unpleasant taste remains and is completely unbalanced.
2 points ... An unpleasant taste remains and is quite unbalanced.
3 points: An unpleasant taste remains and is in an unacceptable range.
4 points ... Slightly unbalanced, but no problem.
5 points ... well balanced and no unpleasant taste.

D: Evaluation condition of “overall finish” 1 point: I don't want to eat because it's tasteless.
2 points ... You can eat delicious taste.
3 points: Not delicious or delicious.
4 points ... delicious.
5 points ... very delicious.

  As is apparent from Table 1, the health supplements of Examples 1 and 2 in which all masking ingredients are contained within the scope of the present invention are “pre-taste”, “middle taste”, “aftertaste”, “overall” “Finish” was highly evaluated. In particular, the health supplement of Example 2 containing blueberry juice powder added a refreshing feeling and was able to obtain a particularly high evaluation.

  On the other hand, Comparative Example 1 containing no masking component was the lowest evaluation in all evaluations. Moreover, although the comparative example 2 which replaced with the masking component and contained the fragrance | flavor is higher than the comparative example 1, the evaluation as a whole is low. Moreover, although the comparative example 3 which contained only the masking component A within the scope of the present invention had a good evaluation of “pre-taste”, the evaluation as a whole was low. Moreover, although the comparative example 4 in which only the masking component B was contained within the scope of the present invention was "harmony of fore and after taste" was higher than those of comparative examples 1 to 3, the overall evaluation was still low. became. Further, Comparative Example 5 in which only the masking component C is contained within the scope of the present invention has a high overall evaluation as compared with Comparative Examples 1 to 4 due to the sweetness of aspartame, but it can suppress the bitterness of the “pre-taste”. In comparison with Examples 1 and 2, the overall evaluation was low.

Claims (3)

A health supplement containing arginine,
1-80% by weight of arginine, 0.05-5% by weight of d-ribose, 0.2-20% by weight of sorbitol, 0.5-50% by weight of malic acid, based on the total weight of the health supplement A health supplement comprising aspartame in a proportion of 0.1 to 10% by mass.   The health supplement according to claim 1, further comprising 0.05 to 5% by mass of fruit juice powder based on the total mass of the health supplement.   The health supplement according to claim 1 or 2, wherein the fruit juice powder is blueberry fruit juice powder.

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