JP5253303B2 - 種々のサンプル量を受容するための検体試験片 - Google Patents
種々のサンプル量を受容するための検体試験片 Download PDFInfo
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- JP5253303B2 JP5253303B2 JP2009146468A JP2009146468A JP5253303B2 JP 5253303 B2 JP5253303 B2 JP 5253303B2 JP 2009146468 A JP2009146468 A JP 2009146468A JP 2009146468 A JP2009146468 A JP 2009146468A JP 5253303 B2 JP5253303 B2 JP 5253303B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
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Description
Claims (16)
- 種々の体液サンプル量を受け取り、前記体液サンプルの中の検体を測定するための検体試験片であって、
前記検体試験片は、
第1の絶縁層と、
前記第1の絶縁層の上に配置される第2の絶縁層と、
前記第1の絶縁層の下に少なくとも部分的に配置される第3の絶縁層であって、前記第3の絶縁層は、前記第1の絶縁層および前記第2の絶縁層の下に延在するプラットフォーム部であって、前記プラットフォーム部は上面を有するプラットフォーム部を備える第3の絶縁層と、
前記第1の絶縁層と前記第2の絶縁層との間に配置される型どられたスペーサー層であって、前記型どられたスペーサー層は、前記第1の絶縁層と前記第2の絶縁層との間にチャネルを規定し、前記チャネルは、前記チャネル内にサンプル受容チャンバと、前記プラットフォーム部に近接する第1のポートと、前記検体試験片の外側縁における第2のポートと、を有するスペーサー層とを備え、
前記第1のポートおよび前記第2のポートは、前記サンプル受容チャンバと流体連絡し、
前記プラットフォーム部の前記上面は、前記第1のポートから外側に延在し、少なくとも5μlの第1の体液サンプルを受容して、前記体液サンプルの少なくとも一部を、前記第1のポートを介して前記サンプル受容チャンバに移動させるように構成され、
前記第2のポートは、前記第1の体液サンプルよりも少ない量の第2の体液サンプルを受容して、前記第2の体液サンプルの少なくとも一部を前記サンプル受容チャンバに移動させるように構成される、検体試験片。 - 前記第3の絶縁層はまた、前記第1の絶縁層および前記第2の絶縁層を越えて延在し、前記プラットフォーム部の近くに配置されるハンドル部を有する、請求項1に記載の検体試験片。
- 前記プラットフォーム部の前記上面は、前記第1の体液サンプルの過剰な部分を保持するように構成される、請求項1又は2に記載の検体試験片。
- 第1の電極と、第2の電極と、をさらに含み、
前記第1の電極および前記第2の電極は、前記第1の絶縁層に配置され、
前記第1の電極および前記第2の電極は、前記第1の体液サンプルおよび前記第2の体液サンプルのいずれかにおける検体の電気化学ベースの測定のために構成される、請求項1から3のいずれかに記載の検体試験片。 - 前記第1の絶縁層に配置される第1の電極と、前記第2の絶縁層に配置される第2の電極と、をさらに含む、請求項1から4のいずれかに記載の検体試験片。
- 前記第2の体液サンプルは、前記第2のポートに近接して配置される指からしぼり出される血液サンプルである、請求項1から5のいずれかに記載の検体試験片。
- 前記第1の体液サンプルは、シリンジおよびピペットのうちの1つから前記プラットフォームの前記上面に受け取られた血液サンプルである、請求項1から6のいずれかに記載の検体試験片。
- 前記プラットフォーム部は、前記第1の体液サンプルの少なくとも一部を、前記第1のポートを介して、前記チャネルに侵入させるようにする所定の表面自由エネルギーを有する、請求項1から7のいずれかに記載の検体試験片。
- 過剰な量の前記第1の体液サンプルを吸収するように構成される、前記プラットフォーム部に配置される吸収性層をさらに含む、請求項1から8のいずれかに記載の検体試験片。
- 前記プラットフォーム部は、前記第1の体液サンプルを前記プラットフォームの前記上面への適用に導くように構成される切り込みを有する、請求項1から6のいずれかに記載の検体試験片。
- 前記プラットフォーム部は、約4mm2〜約56mm2の範囲の領域を有する、請求項1から10のいずれかに記載の検体試験片。
- 前記第1の体液サンプルは、少なくも25μlの体積を有し、前記第2の体液サンプルは、1μl未満の体積を有する、請求項1から11のいずれかに記載の検体試験片。
- 前記第2のポートは、前記検体試験片の外側縁に存在する、請求項1から12のいずれかに記載の検体試験片。
- 前記第2のポートは、前記検体試験片の近位端外側縁に存在する、請求項1から13のいずれかに記載の検体試験片。
- 前記検体試験片は、検体の電気化学ベースの測定のために構成される、請求項1から14のいずれかに記載の検体試験片。
- 前記検体試験片は、検体の比色分析ベースの測定のために構成される、請求項1から14のいずれかに記載の検体試験片。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US12/145,314 US7922985B2 (en) | 2008-06-24 | 2008-06-24 | Analyte test strip for accepting diverse sample volumes |
US12/145,314 | 2008-06-24 |
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JP2010008411A JP2010008411A (ja) | 2010-01-14 |
JP5253303B2 true JP5253303B2 (ja) | 2013-07-31 |
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JP2009146468A Expired - Fee Related JP5253303B2 (ja) | 2008-06-24 | 2009-06-19 | 種々のサンプル量を受容するための検体試験片 |
Country Status (8)
Country | Link |
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US (1) | US7922985B2 (ja) |
EP (1) | EP2138846B1 (ja) |
JP (1) | JP5253303B2 (ja) |
AT (1) | ATE545024T1 (ja) |
AU (1) | AU2009202506B2 (ja) |
CA (1) | CA2669685A1 (ja) |
ES (1) | ES2379219T3 (ja) |
HK (1) | HK1139207A1 (ja) |
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CN101865852A (zh) * | 2010-03-16 | 2010-10-20 | 苏州市玮琪生物科技有限公司 | 一种总胆固醇比色卡 |
KR20140069324A (ko) * | 2011-10-03 | 2014-06-09 | 씨피필름즈 인코포레이티드 | 글루코스 측정을 위한 귀금속의 활성화 방법 및 관련 바이오센서 전극 |
JP2015503767A (ja) | 2012-01-16 | 2015-02-02 | エイブラム サイエンティフィック,インコーポレーテッド | 流体の物理的特性を測定するための方法、デバイス、およびシステム |
US20130228475A1 (en) * | 2012-03-02 | 2013-09-05 | Cilag Gmbh International | Co-facial analytical test strip with stacked unidirectional contact pads and inert carrier substrate |
US9217723B2 (en) * | 2012-03-02 | 2015-12-22 | Cilag Gmbh International | Co-facial analytical test strip with stacked unidirectional contact pads |
CN104603607A (zh) | 2012-09-07 | 2015-05-06 | 西拉格国际有限责任公司 | 电化学传感器及其制造方法 |
CN102954989A (zh) * | 2012-11-30 | 2013-03-06 | 北京宏元兴邦科技有限责任公司 | 一种电化学感测试片 |
US9121050B2 (en) | 2013-03-15 | 2015-09-01 | American Sterilizer Company | Non-enzyme based detection method for electronic monitoring of biological indicator |
US8858884B2 (en) | 2013-03-15 | 2014-10-14 | American Sterilizer Company | Coupled enzyme-based method for electronic monitoring of biological indicator |
WO2015112323A1 (en) * | 2014-01-22 | 2015-07-30 | Board Of Trustees Of The Leland Stanford Junior University | Re-usable analyte detector and methods |
US11614474B2 (en) * | 2020-07-24 | 2023-03-28 | Dkl International, Inc. | Remote detection of animate entities |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
CA1315181C (en) | 1987-04-13 | 1993-03-30 | Joel M. Blatt | Test strip device with volume metering capillary gap |
DE68924026T3 (de) * | 1988-03-31 | 2008-01-10 | Matsushita Electric Industrial Co., Ltd., Kadoma | Biosensor und dessen herstellung. |
US5437999A (en) * | 1994-02-22 | 1995-08-01 | Boehringer Mannheim Corporation | Electrochemical sensor |
AUPN363995A0 (en) | 1995-06-19 | 1995-07-13 | Memtec Limited | Electrochemical cell |
US6241862B1 (en) | 1996-02-14 | 2001-06-05 | Inverness Medical Technology, Inc. | Disposable test strips with integrated reagent/blood separation layer |
US5708247A (en) | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
JPH10170471A (ja) * | 1996-12-06 | 1998-06-26 | Casio Comput Co Ltd | バイオセンサ |
DE19753847A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Analytisches Testelement mit Kapillarkanal |
US5997817A (en) * | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
US6338790B1 (en) * | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
JP2000241353A (ja) * | 1999-02-18 | 2000-09-08 | Matsushita Electric Ind Co Ltd | 溶液測定装置および溶液測定用容器 |
US6923894B2 (en) * | 1999-11-11 | 2005-08-02 | Apex Biotechnology Corporation | Biosensor with multiple sampling ways |
IL151914A0 (en) | 2000-03-31 | 2003-04-10 | Lifescan Inc | Electrically-conductive patterns for monitoring the filling of medical devices |
JP4177662B2 (ja) * | 2000-07-24 | 2008-11-05 | 松下電器産業株式会社 | バイオセンサ |
CN100346158C (zh) * | 2000-11-30 | 2007-10-31 | 松下电器产业株式会社 | 基质的定量方法 |
US20030180814A1 (en) | 2002-03-21 | 2003-09-25 | Alastair Hodges | Direct immunosensor assay |
DE10220296A1 (de) * | 2002-05-07 | 2003-11-20 | Roche Diagnostics Gmbh | Vorrichtung zur Probennahme von flüssigen Proben |
AU2003284512A1 (en) | 2002-12-02 | 2004-06-23 | Arkray, Inc. | Analysis instrument |
US20040214345A1 (en) | 2003-04-23 | 2004-10-28 | Matzinger David P. | Ambidextrous capillary-filled test strip |
US7927548B2 (en) * | 2005-01-27 | 2011-04-19 | Bamburgh Marsh Llc | Specimen sample collection device and test system |
WO2005117556A2 (en) | 2004-06-02 | 2005-12-15 | Relia Diagnostic Systems, Llc | Quantitative lateral flow system and assay |
EP1637882B1 (de) * | 2004-09-09 | 2007-08-08 | Analyticon Biotechnologies AG | Lateralflussmessvorrichtung und Messverfahren für Analyten |
SE528638C2 (sv) | 2005-04-08 | 2007-01-09 | Boule Medical Ab | Anordning för fyllning av en enhet för bestämning av en provvolym |
US7749371B2 (en) | 2005-09-30 | 2010-07-06 | Lifescan, Inc. | Method and apparatus for rapid electrochemical analysis |
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2008
- 2008-06-24 US US12/145,314 patent/US7922985B2/en active Active
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2009
- 2009-06-19 JP JP2009146468A patent/JP5253303B2/ja not_active Expired - Fee Related
- 2009-06-23 CA CA002669685A patent/CA2669685A1/en not_active Abandoned
- 2009-06-23 AU AU2009202506A patent/AU2009202506B2/en not_active Ceased
- 2009-06-23 EP EP09251625A patent/EP2138846B1/en not_active Not-in-force
- 2009-06-23 AT AT09251625T patent/ATE545024T1/de active
- 2009-06-23 ES ES09251625T patent/ES2379219T3/es active Active
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Publication number | Publication date |
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ATE545024T1 (de) | 2012-02-15 |
EP2138846B1 (en) | 2012-02-08 |
HK1139207A1 (en) | 2010-09-10 |
EP2138846A1 (en) | 2009-12-30 |
ES2379219T3 (es) | 2012-04-23 |
AU2009202506B2 (en) | 2013-10-31 |
JP2010008411A (ja) | 2010-01-14 |
US7922985B2 (en) | 2011-04-12 |
US20090317297A1 (en) | 2009-12-24 |
CA2669685A1 (en) | 2009-12-24 |
AU2009202506A1 (en) | 2010-01-14 |
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