JP5213252B2 - 一体化したバイオセンサを有するカテーテル - Google Patents
一体化したバイオセンサを有するカテーテル Download PDFInfo
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- JP5213252B2 JP5213252B2 JP2008556470A JP2008556470A JP5213252B2 JP 5213252 B2 JP5213252 B2 JP 5213252B2 JP 2008556470 A JP2008556470 A JP 2008556470A JP 2008556470 A JP2008556470 A JP 2008556470A JP 5213252 B2 JP5213252 B2 JP 5213252B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M2025/0034—Multi-lumen catheters with stationary elements characterized by elements which are assembled, connected or fused, e.g. splittable tubes, outer sheaths creating lumina or separate cores
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M25/0032—Multi-lumen catheters with stationary elements characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Description
本特許出願は、本出願の譲受人に譲渡され、かつ、本明細書において参考として特に援用される、2006年2月27日出願の米国仮特許出願第60/777,030号に対する優先権を主張する。
本発明は、概して、医療の用途において使用されるカテーテルに関する。さらに詳細には、本発明は、生理的パラメータを検出するための一体化したバイオセンサを有する複管腔の中心静脈カテーテル(CVC)に関する。
本発明は、静脈内バイオセンサの、インサイチュでの配置のための信頼性のあるシステムを提供する。カテーテル、例えば複管腔カテーテル、中心静脈カテーテル(CVC)、末梢挿入中心カテーテル(peripherally inserted central catheter)(PICC)、または他の普通に使用される末梢静脈(IV)ラインは、バイオセンサの効果的な静脈内の配置に対する適切なプラットホームを提供し得る。本発明は、これらのタイプのデバイスのうちの任意のものを使用して使用され得るが、例示だけのために、本発明は複数の管腔CVCに対する使用に関して提示される。静脈内のバイオセンサを設置するためのプラットホームとしてCVCを使用する一つの利点は、バイオセンサが豊富な血流に露出され得る身体の最も大きな血管に到達するその能力であり得る。さらに、本発明の特定の実施形態は、複数の管腔カテーテルによる使用のために経済的に使用され得る。従って、本発明は、カテーテルに対する普遍的な適用を有するように意図されている。
Claims (16)
- 血管内の生理的パラメータを検出するためのカテーテルであって、
長手方向軸を有する細長いチューブと、
該チューブの近位端と遠位端との間の該チューブの外壁に穴を開けた検知ポートと、
該チューブを通って長手方向に延び、かつ、該検知ポートに接続している少なくとも1つの管腔であって、該管腔は、該チューブの該長手方向軸からずれた長手方向軸を有する、少なくとも1つの管腔と、
該検知ポートを跨ぎ、かつ、該管腔内に同心で配置されている支持部材と、
該支持部材に接続され、かつ、該検知ポートを介して露出されるバイオセンサと、
該検知ポートに対して遠位に該チューブの該外壁に形成された1つ以上の中間ポートと
を備えており、
該検知ポートは、該チューブの該外壁に形成された全ての他のポートに対して近位にある、カテーテル。 - 前記支持部材は、前記カテーテルの内壁から前記バイオセンサの能動部分を離す、請求項1に記載のカテーテル。
- 前記バイオセンサは、前記支持部材の中に同心で取り付けられている、請求項1に記載のカテーテル。
- 前記センサは、前記チューブの前記外壁の内径に取り付けられている、請求項1に記載のカテーテル。
- 前記検知ポートを通って前記管腔の中へ流体が通過することを防止する密封剤をさらに備えている、請求項1に記載のカテーテル。
- 前記管腔は、前記検知ポートを通って該管腔の遠位端の中へ流体が通過することを防止するように、該検知ポートの遠位端において密封され、該検知ポートの近位端を通って該管腔から流体が通過することを可能にするように、該検知ポートの近位端に対して開いている、請求項1に記載のカテーテル。
- 血管内の生理的パラメータを検出するカテーテルであって、
細長いチューブと、
該チューブの近位端と遠位端との間の該チューブの外壁に形成されたくぼんだエリアと、
該チューブを通って長手方向に延び、かつ、該くぼんだエリアの内壁を形成する少なくとも1つの管腔と、
該くぼんだエリアの横の近位壁を貫通して形成される取り付けポートと、
該取り付けポートを通って延び、かつ、該くぼんだエリアにおいて該チューブの該外壁に接合されているバイオセンサと
を備えており、そして
該くぼんだエリアに対して遠位において該チューブの該外壁に形成された1つ以上の中間ポートを備えており、
該くぼんだエリアは、該取り付けポート以外の該チューブの該外壁に形成された全ての他のポートに対して近位にある、カテーテル。 - 前記取り付けポートは、そこを通る流体の通過を防止するために密封されている、請求項7に記載のカテーテル。
- 前記くぼんだエリアの横の遠位壁を貫通して形成される第2の取り付けポートをさらに備えており、前記バイオセンサは、該第2の取り付けポートを通って延びている、請求項7に記載のカテーテル。
- 前記第1および第2の取り付けポートは、それらを通る流体の通過を防止するために密封されている、請求項9に記載のカテーテル。
- 前記バイオセンサの最外面は、前記チューブの軸から半径方向の距離を離され、該半径方向の距離は、該チューブの外壁の半径を下回る、請求項7に記載のカテーテル。
- 血管内の生理的パラメータを検出するためのカテーテルであって、
長手方向軸を有する細長いチューブと、
該チューブの近位端と遠位端との間の該チューブの外壁に穴を開けた検知ポートと、
該チューブの近位端から該チューブを通って長手方向に延び、かつ、該検知ポートの遠位端において終端している少なくとも1つの管腔であって、該管腔は、該チューブの該長手方向軸からずれた長手方向軸を有する、少なくとも1つの管腔と、
該管腔を通って該検知ポートに延びているプローブと、
該プローブに接続され、かつ、該検知ポートを介して露出されるバイオセンサと、
該検知ポートに対して遠位に該チューブの該外壁に形成された1つ以上の中間ポートと
を備えており、
該検知ポートは、該チューブの該外壁に形成された全ての他のポートに対して近位にある、カテーテル。 - 前記プローブは、前記カテーテルの内壁から前記バイオセンサの能動部分を離す、請求項12に記載のカテーテル。
- 前記バイオセンサは、前記プローブに対して同心で取り付けられている、請求項12に記載のカテーテル。
- 前記検知ポートの遠位端において、前記管腔内に配置されたプラグをさらに備えている、請求項12に記載のカテーテル。
- 前記管腔は、該管腔を通って前記プローブを適切な向きに誘導するように調節され、該プローブの遠位端が前記プラグに到達したときに、前記検知ポートを介して前記バイオセンサの能動部分を露出させる、請求項15に記載のカテーテル。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77703006P | 2006-02-27 | 2006-02-27 | |
US60/777,030 | 2006-02-27 | ||
PCT/US2007/005020 WO2007100796A2 (en) | 2006-02-27 | 2007-02-26 | Catheter with integral biosensor |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009528085A JP2009528085A (ja) | 2009-08-06 |
JP5213252B2 true JP5213252B2 (ja) | 2013-06-19 |
Family
ID=38293371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008556470A Expired - Fee Related JP5213252B2 (ja) | 2006-02-27 | 2007-02-26 | 一体化したバイオセンサを有するカテーテル |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070219441A1 (ja) |
EP (1) | EP1945291A2 (ja) |
JP (1) | JP5213252B2 (ja) |
CN (1) | CN101355980A (ja) |
CA (1) | CA2630533A1 (ja) |
WO (1) | WO2007100796A2 (ja) |
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2007
- 2007-02-26 US US11/710,834 patent/US20070219441A1/en not_active Abandoned
- 2007-02-26 CA CA002630533A patent/CA2630533A1/en not_active Abandoned
- 2007-02-26 EP EP07751754A patent/EP1945291A2/en not_active Withdrawn
- 2007-02-26 CN CNA2007800013743A patent/CN101355980A/zh active Pending
- 2007-02-26 WO PCT/US2007/005020 patent/WO2007100796A2/en active Application Filing
- 2007-02-26 JP JP2008556470A patent/JP5213252B2/ja not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8939115B2 (en) | 2009-11-18 | 2015-01-27 | Harley-Davidson Motor Company Group, LLC | Cylinder head cooling system |
JP7200284B2 (ja) | 2021-03-31 | 2023-01-06 | 本田技研工業株式会社 | 鞍乗り型車両 |
Also Published As
Publication number | Publication date |
---|---|
CA2630533A1 (en) | 2007-09-07 |
WO2007100796A3 (en) | 2007-11-01 |
WO2007100796A2 (en) | 2007-09-07 |
CN101355980A (zh) | 2009-01-28 |
EP1945291A2 (en) | 2008-07-23 |
JP2009528085A (ja) | 2009-08-06 |
US20070219441A1 (en) | 2007-09-20 |
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