JP5143012B2 - アテローム性動脈硬化プラークの神経刺激治療システム - Google Patents

アテローム性動脈硬化プラークの神経刺激治療システム Download PDF

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Publication number
JP5143012B2
JP5143012B2 JP2008541206A JP2008541206A JP5143012B2 JP 5143012 B2 JP5143012 B2 JP 5143012B2 JP 2008541206 A JP2008541206 A JP 2008541206A JP 2008541206 A JP2008541206 A JP 2008541206A JP 5143012 B2 JP5143012 B2 JP 5143012B2
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lead
atherosclerosis
nerve
site
therapy
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Expired - Fee Related
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Japanese (ja)
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JP2009516540A5 (https=
JP2009516540A (ja
Inventor
リバス，イマド
シー． スピネリ，ジュリオ
コレット ベイナム，タマラ
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カーディアック ペースメイカーズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Electrotherapy Devices (AREA)
JP2008541206A 2005-11-21 2006-11-02 アテローム性動脈硬化プラークの神経刺激治療システム Expired - Fee Related JP5143012B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/284,370 2005-11-21
US11/284,370 US7630760B2 (en) 2005-11-21 2005-11-21 Neural stimulation therapy system for atherosclerotic plaques
PCT/US2006/042866 WO2007058788A1 (en) 2005-11-21 2006-11-02 Neural stimulation therapy system for atherosclerotic plaques

Publications (3)

Publication Number Publication Date
JP2009516540A JP2009516540A (ja) 2009-04-23
JP2009516540A5 JP2009516540A5 (https=) 2009-12-24
JP5143012B2 true JP5143012B2 (ja) 2013-02-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008541206A Expired - Fee Related JP5143012B2 (ja) 2005-11-21 2006-11-02 アテローム性動脈硬化プラークの神経刺激治療システム

Country Status (4)

Country Link
US (2) US7630760B2 (https=)
EP (1) EP1951369A1 (https=)
JP (1) JP5143012B2 (https=)
WO (1) WO2007058788A1 (https=)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
CN102793972A (zh) 2004-12-27 2012-11-28 范因斯坦医学研究院 通过电刺激迷走神经治疗炎症性疾病
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US7630760B2 (en) * 2005-11-21 2009-12-08 Cardiac Pacemakers, Inc. Neural stimulation therapy system for atherosclerotic plaques
WO2008070189A2 (en) 2006-12-06 2008-06-12 The Cleveland Clinic Foundation Method and system for treating acute heart failure by neuromodulation
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
US8391986B2 (en) 2008-05-13 2013-03-05 The Board Of Trustees Of The University Of Illinois Apparatus for managing a neurological disorder
EP2341981A2 (en) * 2008-07-16 2011-07-13 Cardiac Pacemakers, Inc. Intermittent pacing therapy for angina and disease prevention
US20100016916A1 (en) * 2008-07-16 2010-01-21 Shantha Arcot-Krishnamurthy Apparatus and methods for treatment of atherosclerosis and infarction
EP2362747A1 (en) * 2008-09-23 2011-09-07 Cardiac Pacemakers, Inc. Method and apparatus for organ specific inflammation monitoring
US8280516B2 (en) 2008-10-09 2012-10-02 Daniel Graupe Method and apparatus for closed-loop deep brain stimulation in treating neurological diseases
US10603489B2 (en) 2008-10-09 2020-03-31 Virender K. Sharma Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
WO2010054116A1 (en) * 2008-11-10 2010-05-14 Cardiac Pacemakers, Inc. Distal end converter for a medical device lead
ES2452484T3 (es) 2008-11-18 2014-04-01 Setpoint Medical Corporation Dispositivos para optimizar la colocación de electrodos para la estimulación antiinflamatoria
US20100256700A1 (en) * 2009-04-07 2010-10-07 Shuros Allan C Method and apparatus for organ specific inflammation therapy
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
EP2427056A4 (en) * 2009-05-07 2012-08-22 Univ Cincinnati METHODS FOR PREVENTING ISCHEMIC LESION BY STIMULATION OF PERIPHERAL NICE PERIPHERAL
US8954167B2 (en) 2009-05-26 2015-02-10 Cardiac Pacemakers, Inc. Helically formed coil for a neural cuff electrode
WO2010144578A2 (en) 2009-06-09 2010-12-16 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
CN105126248B (zh) 2009-12-23 2018-06-12 赛博恩特医疗器械公司 用于治疗慢性炎症的神经刺激设备和系统
US9433459B2 (en) 2010-07-13 2016-09-06 Zoll Medical Corporation Deposit ablation within and external to circulatory systems
WO2012009445A1 (en) * 2010-07-13 2012-01-19 Zoll Medical Corporation Deposit ablation within and external to circulatory systems
EP3002037B1 (en) 2010-09-15 2018-06-06 Cardiac Pacemakers, Inc. Automatic selection of lead configuration for a neural stimulation lead
EP2707094B1 (en) 2011-05-09 2016-02-03 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
EP2726142B1 (en) 2011-06-28 2017-05-10 Cardiac Pacemakers, Inc. Strain relief feature for an implantable medical device lead
AU2012279403B2 (en) 2011-07-07 2015-05-28 Cardiac Pacemakers, Inc. Insulation and stability features for an implantable medical device lead
US8918191B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
US8577458B1 (en) 2011-12-07 2013-11-05 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with leadless heart rate monitoring
US8630709B2 (en) 2011-12-07 2014-01-14 Cyberonics, Inc. Computer-implemented system and method for selecting therapy profiles of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8918190B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction
US8600505B2 (en) 2011-12-07 2013-12-03 Cyberonics, Inc. Implantable device for facilitating control of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US10188856B1 (en) 2011-12-07 2019-01-29 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
AU2012351954B2 (en) 2011-12-15 2016-08-11 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for treating pulmonary hypertension
US8700150B2 (en) 2012-01-17 2014-04-15 Cyberonics, Inc. Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
US8571654B2 (en) 2012-01-17 2013-10-29 Cyberonics, Inc. Vagus nerve neurostimulator with multiple patient-selectable modes for treating chronic cardiac dysfunction
WO2013134543A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Immune system neuromodulation and associated systems and methods
JP6026567B2 (ja) 2012-03-21 2016-11-16 カーディアック ペースメイカーズ， インコーポレイテッド 迷走神経を刺激するためのシステムおよび方法
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US8688212B2 (en) 2012-07-20 2014-04-01 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing bradycardia through vagus nerve stimulation
WO2014055408A1 (en) 2012-10-02 2014-04-10 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
EP2903685B1 (en) 2012-10-02 2019-08-07 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
US9643008B2 (en) 2012-11-09 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing post-exercise recovery through vagus nerve stimulation
US8923964B2 (en) 2012-11-09 2014-12-30 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing heart failure patient awakening through vagus nerve stimulation
US9452290B2 (en) 2012-11-09 2016-09-27 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmia through vagus nerve stimulation
CN102908191A (zh) 2012-11-13 2013-02-06 陈绍良 多极同步肺动脉射频消融导管
US11241267B2 (en) 2012-11-13 2022-02-08 Pulnovo Medical (Wuxi) Co., Ltd Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
US9827036B2 (en) 2012-11-13 2017-11-28 Pulnovo Medical (Wuxi) Co., Ltd. Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
US12082868B2 (en) 2012-11-13 2024-09-10 Pulnovo Medical (Wuxi) Co., Ltd. Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
WO2014106023A1 (en) 2012-12-28 2014-07-03 Cardiac Pacemakers, Inc. Stimulation cuff and implantation tool
US9320889B2 (en) 2013-02-13 2016-04-26 Cardiac Pacemakers, Inc. Cuff electrode with integrated tendril
US9643011B2 (en) 2013-03-14 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmic risk during sleep through vagus nerve stimulation
US9999773B2 (en) 2013-10-30 2018-06-19 Cyberonics, Inc. Implantable neurostimulator-implemented method utilizing multi-modal stimulation parameters
US9511228B2 (en) 2014-01-14 2016-12-06 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing hypertension through renal denervation and vagus nerve stimulation
US9409024B2 (en) 2014-03-25 2016-08-09 Cyberonics, Inc. Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction
US9713719B2 (en) 2014-04-17 2017-07-25 Cyberonics, Inc. Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction
US9415224B2 (en) 2014-04-25 2016-08-16 Cyberonics, Inc. Neurostimulation and recording of physiological response for the treatment of chronic cardiac dysfunction
US9272143B2 (en) 2014-05-07 2016-03-01 Cyberonics, Inc. Responsive neurostimulation for the treatment of chronic cardiac dysfunction
US9950169B2 (en) 2014-04-25 2018-04-24 Cyberonics, Inc. Dynamic stimulation adjustment for identification of a neural fulcrum
WO2015179634A2 (en) 2014-05-22 2015-11-26 CARDIONOMIC, Inc. Catheter and catheter system for electrical neuromodulation
US9533153B2 (en) 2014-08-12 2017-01-03 Cyberonics, Inc. Neurostimulation titration process
US9737716B2 (en) 2014-08-12 2017-08-22 Cyberonics, Inc. Vagus nerve and carotid baroreceptor stimulation system
US9770599B2 (en) 2014-08-12 2017-09-26 Cyberonics, Inc. Vagus nerve stimulation and subcutaneous defibrillation system
WO2016040037A1 (en) 2014-09-08 2016-03-17 CARDIONOMIC, Inc. Catheter and electrode systems for electrical neuromodulation
EP3194017A1 (en) 2014-09-08 2017-07-26 Cardionomic, Inc. Methods for electrical neuromodulation of the heart
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US9504832B2 (en) 2014-11-12 2016-11-29 Cyberonics, Inc. Neurostimulation titration process via adaptive parametric modification
JP2017536187A (ja) 2014-12-03 2017-12-07 メタベンション インコーポレイテッド 神経または他の組織を調節するためのシステムおよび方法
US10493278B2 (en) 2015-01-05 2019-12-03 CARDIONOMIC, Inc. Cardiac modulation facilitation methods and systems
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
CN108882885A (zh) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 迷走神经刺激的控制
US10314501B2 (en) 2016-01-20 2019-06-11 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
WO2017155916A1 (en) * 2016-03-07 2017-09-14 Sharma Virender K Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
CN109310863A (zh) 2016-03-09 2019-02-05 卡迪诺米克公司 心脏收缩性神经刺激系统和方法
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
EP3664703A4 (en) 2017-09-13 2021-05-12 Cardionomic, Inc. NEUROSTIMULATION SYSTEMS AND METHODS FOR INFLUENCING HEART CONTRACTILITY
JP2021535776A (ja) 2018-08-13 2021-12-23 カーディオノミック，インク． 心収縮及び／又は弛緩に作用するシステムおよび方法
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
US12343535B2 (en) 2019-04-12 2025-07-01 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
CA3137307A1 (en) 2019-05-06 2020-11-12 CARDIONOMIC, Inc. Systems and methods for denoising physiological signals during electrical neuromodulation
AU2021207815B2 (en) 2020-01-13 2026-03-26 The Feinstein Institutes For Medical Research Treating bleeding and bleeding disorders via high intensity focused ultrasound stimulation of the spleen
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
WO2021257399A1 (en) 2020-06-16 2021-12-23 CARDIONOMIC, Inc. Chronically implantable systems and methods for affecting cardiac contractility and/or relaxation
US12502531B2 (en) 2021-04-26 2025-12-23 Manicka Institute Llc Subcutaneous device for preventing and treating atherosclerosis
WO2022245878A1 (en) 2021-05-17 2022-11-24 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
EP4108197A1 (en) 2021-06-24 2022-12-28 Gradient Denervation Technologies Systems for treating tissue
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
US12427086B1 (en) * 2025-07-25 2025-09-30 R. David Brown Steam room and sauna emergency monitoring system and apparatus

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7269457B2 (en) * 1996-04-30 2007-09-11 Medtronic, Inc. Method and system for vagal nerve stimulation with multi-site cardiac pacing
US6201991B1 (en) * 1999-05-07 2001-03-13 Heart Care Associates, Llc Method of prevention and treatment of atherosclerosis and article of manufacture therefor
US8914114B2 (en) * 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US7481759B2 (en) * 2001-08-03 2009-01-27 Cardiac Pacemakers, Inc. Systems and methods for treatment of coronary artery disease
US6622041B2 (en) * 2001-08-21 2003-09-16 Cyberonics, Inc. Treatment of congestive heart failure and autonomic cardiovascular drive disorders
US7885709B2 (en) * 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
US7773112B2 (en) * 2002-08-20 2010-08-10 Tektronix, Inc. Automatic measurement of video parameters
US20040122477A1 (en) * 2002-12-19 2004-06-24 Whitehurst Todd K. Fully implantable miniature neurostimulator for spinal nerve root stimulation as a therapy for angina and peripheral vascular disease
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
EP1648558A4 (en) 2003-06-13 2015-05-27 Biocontrol Medical B C M Ltd APPLICATIONS OF VAGAL STIMULATION
US7711432B2 (en) * 2004-07-26 2010-05-04 Advanced Neuromodulation Systems, Inc. Stimulation system and method for treating a neurological disorder
CN102793972A (zh) * 2004-12-27 2012-11-28 范因斯坦医学研究院 通过电刺激迷走神经治疗炎症性疾病
US20070021786A1 (en) * 2005-07-25 2007-01-25 Cyberonics, Inc. Selective nerve stimulation for the treatment of angina pectoris
US7630760B2 (en) 2005-11-21 2009-12-08 Cardiac Pacemakers, Inc. Neural stimulation therapy system for atherosclerotic plaques
US20070185525A1 (en) * 2006-02-07 2007-08-09 White Bradley R Floating on the wire filter wire
US20080167690A1 (en) * 2007-01-05 2008-07-10 Cvrx, Inc. Treatment of peripheral vascular disease by baroreflex activation

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Publication number Publication date
EP1951369A1 (en) 2008-08-06
US7630760B2 (en) 2009-12-08
US20070118177A1 (en) 2007-05-24
JP2009516540A (ja) 2009-04-23
US20070185535A1 (en) 2007-08-09
WO2007058788A1 (en) 2007-05-24

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