JP5142676B2 - 選択励起周波数による代謝産物に対する高速mr撮像のためのシステム - Google Patents
選択励起周波数による代謝産物に対する高速mr撮像のためのシステム Download PDFInfo
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- JP5142676B2 JP5142676B2 JP2007294989A JP2007294989A JP5142676B2 JP 5142676 B2 JP5142676 B2 JP 5142676B2 JP 2007294989 A JP2007294989 A JP 2007294989A JP 2007294989 A JP2007294989 A JP 2007294989A JP 5142676 B2 JP5142676 B2 JP 5142676B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4828—Resolving the MR signals of different chemical species, e.g. water-fat imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/446—Multifrequency selective RF pulses, e.g. multinuclear acquisition mode
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
- G01R33/485—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
- G01R33/5613—Generating steady state signals, e.g. low flip angle sequences [FLASH]
- G01R33/5614—Generating steady state signals, e.g. low flip angle sequences [FLASH] using a fully balanced steady-state free precession [bSSFP] pulse sequence, e.g. trueFISP
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/281—Means for the use of in vitro contrast agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
- G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
- G01R33/5616—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using gradient refocusing, e.g. EPI
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
- G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
- G01R33/5617—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using RF refocusing, e.g. RARE
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Description
12 オペレータコンソール
13 入力デバイス
14 制御パネル
16 表示画面
18 リンク
20 コンピュータシステム
20a バックプレーン
22 画像プロセッサモジュール
24 CPUモジュール
26 メモリモジュール
32 システム制御部
32a バックプレーン
34 高速シリアルリンク
40 シリアルリンク
42 傾斜増幅器組
44 スキャン室インタフェース
46 パルスシーケンス送信モジュール
48 スキャナ
50 傾斜コイルアセンブリ
52 マグネットアセンブリ
54 偏向マグネット
56 RFコイルアセンブリ
58 RFコイルアセンブリ
60 データリンク
62 データ処理セクション
66 メモリモジュール
68 アレイプロセッサ
80 スペクトル空間タイプの励起パルス
82 RF下位要素
84 スライスエンコード傾斜
86 横磁化
88 縦磁化プロット
92 主横磁化
94 磁化
96 縦磁化の主低減
98 磁化
100 横磁化
102 縦磁化
104 主横磁化
106 磁化
108 主縦磁化低減
110 縦磁化
112 横磁化
114 縦磁化
116 横磁化
118 横磁化
120 横磁化
122 低下した縦磁化
124 低下した縦磁化
128 データ収集シーケンス
130 スペクトル空間パルス
132 スペクトル空間パルス
134 デフェージング傾斜パルス
136 RFパルス
138 第1の収集
140 リフェージング傾斜
142 第2の収集
143 技法
144 造影剤を導入する
146 第1のパルスを送信する
148 デフェージング傾斜パルスを印加する
150 第2のパルスを送信する
152 幅広の周波数パルスを送信する
154 第2のパルス読み出し
156 リフェージング傾斜パルスを印加する
158 第1のパルス読み出し
160 再構成
Claims (7)
- マグネット(52)のボアの周りに位置決めされた複数の傾斜コイル(50)と、
RFパルスシーケンスを放出するようにパルス発生器(46)と結合されかつ関心対象物から得られたMR信号を受信するように配列されたRFコイル・アセンブリ(56、58)と、
前記複数の傾斜コイル(50)及び前記RFコイル・アセンブリ(56、58)と結合されたシステム制御部(32)であって、
第1のスペクトル空間RFパルス(130)を放出すること、
前記第1のスペクトル空間RFパルス(130)の放出後に、第2のスペクトル空間RFパルス(132)を放出すること、
第1のスペクトル空間RFパルス(130)から得られるMR信号(142)を検出する前に第2のスペクトル空間RFパルス(132)から得られるMR信号(138)を検出すること、
をRFコイル・アセンブリ(56、58)に実行させるようにプログラムされたシステム制御部と、
を備えるMRシステム。 - 前記システム制御部(32)はさらに、第1のスペクトル空間RFパルス(130)の放出と第2のスペクトル空間RFパルス(132)の放出の間にデフェージング傾斜(134)を印加させるようにプログラムされている、請求項1に記載のMRシステム。
- 前記システム制御部(32)はさらに、第2のスペクトル空間RFパルス(132)から得られるMR信号(138)の検出と第1のスペクトル空間RFパルス(130)から得られるMR信号(142)の検出との間にリフェージング傾斜パルス(140)を印加させるようにプログラムされている、請求項2に記載のMRシステム。
- 前記第1のスペクトル空間RFパルス(130)は第1の代謝産物(92)を励起するように設計されており、かつ前記第2のスペクトル空間RFパルス(132)は第2の代謝産物(104)を励起するように設計されている、請求項1に記載のMRシステム。
- 前記システム制御部(32)はさらに、3つ以上のスペクトル空間RFパルス(130、132)を放出させるようにプログラムされている、請求項1に記載のMRシステム。
- 前記システム制御部(32)はさらに、前記3つ以上のスペクトル空間RFパルス(130、132)が放出された順序と逆の順序で該3つ以上のスペクトル空間RFパルス(130、132)の放出から得られたMR信号(138、142)を収集させるようにプログラムされている、請求項5に記載のMRシステム。
- 前記システム制御部はさらに、EPI、RARE、trueFISP読み出しのうちの少なくとも1つを用いてMR信号を検出するようにプログラムされている、請求項1に記載のMRシステム。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/562,391 | 2006-11-21 | ||
US11/562,391 US7719269B2 (en) | 2006-11-21 | 2006-11-21 | System and method for fast MR imaging of metabolites at selective excitation frequencies |
Publications (3)
Publication Number | Publication Date |
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JP2008126069A JP2008126069A (ja) | 2008-06-05 |
JP2008126069A5 JP2008126069A5 (ja) | 2012-10-04 |
JP5142676B2 true JP5142676B2 (ja) | 2013-02-13 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2007294989A Expired - Fee Related JP5142676B2 (ja) | 2006-11-21 | 2007-11-14 | 選択励起周波数による代謝産物に対する高速mr撮像のためのシステム |
Country Status (3)
Country | Link |
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US (2) | US7719269B2 (ja) |
JP (1) | JP5142676B2 (ja) |
DE (1) | DE102007055580A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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DE102007044463B4 (de) * | 2007-09-18 | 2009-05-14 | Bruker Biospin Mri Gmbh | Verfahren zur Bestimmung der räumlichen Verteilung von Magnetresonanzsignalen durch mehrdimensionale HF-Anregungspulse |
US7772844B2 (en) * | 2008-01-30 | 2010-08-10 | General Electric Company | System and method for tissue specific MR imaging of metabolites using spectral-spatially formed stimulated echo |
US8049501B2 (en) * | 2008-04-11 | 2011-11-01 | General Electric Company | Multi-frequency RF coil |
DE102008021736B3 (de) * | 2008-04-30 | 2009-12-10 | Bruker Biospin Mri Gmbh | Verfahren zur Bestimmung der räumlichen Verteilung von Magnetresonanzsignalen beim Einsatz von lokalen ortskodierenden Magnetfeldern |
US7795868B2 (en) * | 2008-10-08 | 2010-09-14 | The Board Of Trustees Of The Leland Stanford Junior University | Hyperpolarized dynamic chemical shift imaging with tailored multiband excitation pulses |
AU2010232430B2 (en) * | 2009-04-03 | 2014-08-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Magnetic microstructures for magnetic resonance imaging |
US8970217B1 (en) | 2010-04-14 | 2015-03-03 | Hypres, Inc. | System and method for noise reduction in magnetic resonance imaging |
CN103380384B (zh) * | 2011-02-15 | 2016-04-06 | 皇家飞利浦有限公司 | 使用交错的水参考扫描的具有自动相位和b0校正的磁共振波谱成像方法和装置 |
US8933697B2 (en) * | 2011-12-19 | 2015-01-13 | General Electric Company | Measurement of chemical equilibrium ratio using a magnetic resonance spectroscopy system |
KR101458557B1 (ko) * | 2013-02-20 | 2014-11-07 | 삼성전자주식회사 | 상이한 숙임각을 갖는 자기 공명 영상 시스템에서 주자장 정보 및 라디오 펄스 관련 정보를 획득하기 위한 방법 및 장치 |
CN107110938B (zh) * | 2014-11-14 | 2019-12-17 | 皇家飞利浦有限公司 | 使用具有额外180度rf脉冲的自旋回波脉冲序列的磁共振指纹 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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US5578921A (en) * | 1995-01-10 | 1996-11-26 | Board Of Trustees Of The Leland Stanford Junior University | Magnetic resonance imaging using three-dimensional spectral-spatial excitation |
DE19610278B4 (de) * | 1995-03-15 | 2007-12-27 | Kabushiki Kaisha Toshiba, Kawasaki | Kernspinresonanz-Untersuchungsverfahren auf Basis verbesserter DEPT-, INEPT-, HSQC- und HMQC-Verfahren |
US6304084B1 (en) * | 1997-04-14 | 2001-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improved magnetic resonance spectroscopic localization using spectral-spatial pulses |
US6275040B1 (en) * | 1999-05-18 | 2001-08-14 | Yuval Zur | Designing spectral-spatial pulses |
US6583623B1 (en) * | 2000-03-31 | 2003-06-24 | University Of Rochester | Interleaved water and fat dual-echo spin echo magnetic resonance imaging with intrinsic chemical shift elimination |
GB0122049D0 (en) * | 2001-09-12 | 2001-10-31 | Nycomed Imaging As | Method |
US7034530B2 (en) * | 2002-06-28 | 2006-04-25 | General Electric Company | Technique for simultaneous acquisition of multiple independent MR imaging volumes with optimization of magnetic field homogeneity for spin preparation |
US6806706B2 (en) * | 2002-11-26 | 2004-10-19 | Ge Medical Systems Global Technology Company, Llc | Modulated chemical shift imaging solvent suppression |
US7042214B2 (en) * | 2004-04-13 | 2006-05-09 | The Board Of Trustees Of The Leland Stanford Junior University | Non-linear symmetric sweep spectral-spatial RF pulses for MR spectroscopy |
US7772844B2 (en) * | 2008-01-30 | 2010-08-10 | General Electric Company | System and method for tissue specific MR imaging of metabolites using spectral-spatially formed stimulated echo |
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2006
- 2006-11-21 US US11/562,391 patent/US7719269B2/en not_active Expired - Fee Related
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2007
- 2007-11-14 JP JP2007294989A patent/JP5142676B2/ja not_active Expired - Fee Related
- 2007-11-20 DE DE102007055580A patent/DE102007055580A1/de not_active Withdrawn
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- 2010-03-08 US US12/719,081 patent/US7952354B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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US20100156417A1 (en) | 2010-06-24 |
JP2008126069A (ja) | 2008-06-05 |
US7719269B2 (en) | 2010-05-18 |
US20080116893A1 (en) | 2008-05-22 |
US7952354B2 (en) | 2011-05-31 |
DE102007055580A1 (de) | 2008-05-29 |
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