JP5112705B2 - Embedding tray for preparation of histopathological specimen - Google Patents

Description

  The present invention relates to an embedding tray for preparing a histopathological specimen, and more particularly, to prevent the cassette from floating due to paraffin when the cassette is placed on the embedding tray to create a paraffin block. The present invention relates to an embedding tray for preparing a histopathological specimen, in which the cassette does not have to be pressed with a finger and is automatically fitted and held by the embedding tray so that the cassette is prevented from being lifted.

  Conventionally, as an embedding tray for preparing this type of histopathological specimen, the one shown in FIG. 28 has been frequently used. The embedding tray T includes a paraffin storage portion T1, a cassette support portion T2 for placing a horizontal cassette on the periphery thereof, and a cassette member for stopping the movement of the cassette standing on the periphery thereof. The stop portion T3 is a frame portion T4 provided horizontally around the periphery of the stop portion T3, and further includes a grip portion T5 provided laterally at a substantially central portion on the long side of the frame portion T4.

  Further, in recent years, it is composed of a paraffin storage portion formed of a rectangular container and a placement portion for a paraffin block adhering body provided at the periphery thereof, and at least two placement portions are provided, and two types having different sizes are provided. A tray for preparing a histopathological examination specimen that can handle the above cassettes is known (for example, see Patent Document 1).

  In order to prepare a microscope specimen using the above-mentioned pathological examination specimen preparation tray, first, as shown in FIGS. 26 and 27, the sample S collected in the cassette body C1 is accommodated and a lid C2 is attached. The name and number of the subject are entered in the recording unit C3. Next, formalin water is allowed to flow through the bottom of the cassette body C1 and the through-hole C4 formed in the lid C2, so that the sample S is familiarized with the alcohol. Then, the moisture of the sample S is removed with alcohol, and liquid paraffin described later with xylene. To give affinity.

  Next, after moving the specimen S to the tray T, as shown in FIG. 29, the paraffin P is injected from above so that the specimen S is immersed. Thereafter, the position and direction of the specimen S are quickly corrected before the paraffin P is cooled and solidified, and then, as shown in FIG. 30, the paraffin P is added until the paraffin container T1 is full. In this case, the paraffin P is gently injected so as to increase the surface tension. Next, as shown in FIG. 31, the cassette body C1 is placed on the raised paraffin P, and the paraffin P is allowed to ooze into the cassette body C1 through the through hole C4 formed in the bottom of the cassette body C1. At this time, it is necessary to firmly press the cassette body C1 with a finger so that the cassette body C1 does not float on the paraffin P. In this state, it is allowed to cool for a while, the surface of the paraffin P is solidified, the cassette body C1 is temporarily fixed on the embedding tray 1, and then the finger is released. Thereafter, as shown in FIG. Add P. Thereafter, after further cooling, the paraffin P is completely solidified, and then the embedding tray T is removed, so that the paraffin P in which the specimen S is embedded adheres to the bottom of the cassette body C1 as shown in FIG. Paraffin block B is obtained. Thereafter, a microscope specimen is obtained in the same manner as described above.

  However, this method is troublesome because it is necessary to keep pressing the cassette C until the surface of the paraffin P is solidified, and there is a risk of burns. In addition, if the pressing force is incorrect, the embedding tray T and the placed cassette body C1 will fall over and the tabletop will be soiled with paraffin, and valuable specimens will be contaminated and ruined, and the reliability of the test will be increased. Will be greatly impaired.

In order to solve the problem caused by pressing the cassette C onto the embedding tray T with a finger as described above, for example, an engaging protrusion C5 is provided on the cassette C as shown in FIG. A method of temporarily holding the cassette C on the embedding tray T by providing an engagement recess T6 and engaging them is also conceivable.
However, this method cannot be performed using a conventional cassette C that does not have the engaging protrusion C5, and it is not economical because not only the embedding tray T but also the cassette C needs to be newly aligned. Further, when engaging them, it is necessary to align the engagement protrusions C5 and the engagement recesses T6. Furthermore, when engaging and disengaging them, the engagement protrusions C5 and the engagement recesses T6 are matched in shape. Therefore, it is necessary to insert and remove in the vertical direction, so both hands must be used, and the work is troublesome and the workability is greatly reduced. That is, when removing the embedding tray T from the cassette block B, for example, when the embedding tray T is removed by holding only one side of the cassette C so as to open the lid, the engaging protrusion C5 is removed from the engaging recess T6. The embedding tray cannot be removed.
JP 2006-300745 A

In view of such circumstances, the present inventors have conducted intensive research to eliminate the above-mentioned problems, and as a result, a holding plate is erected discontinuously on the paraffin container and the interval between the holding plates is detachably fitted. It has been found that by forming to the extent that it is worn, it is not necessary to hold the cassette with fingers when creating the paraffin block, and the embedding tray can be easily detached from the paraffin block, and the above conventional problems can be solved. The present invention has been completed.

The present invention has been made to achieve the above object, and claim 1 of the present invention is an embedding tray for preparing a histopathological specimen that is used by placing a cassette on the upper end of a paraffin container. The paraffin container is composed of a bottom part and side walls erected around the bottom part, and a clamping plate for fitting the cassette on the paraffin container part is discontinuously erected from the upper end of the opposite side wall. The interval is slightly narrower than the cassette width. By inserting the cassette between the clamping plates, the clamping plates are elastically deformed to widen the interval between the opposing clamping plates, and are held by the elastic repulsive force generated thereby. An embedding tray for preparing a histopathological specimen is characterized in that the cassette is sandwiched between plates.

Claim 2 of the present invention is an embedding tray for preparing a histopathological specimen that is used by placing a cassette on the upper end of the paraffin storage section, wherein the paraffin storage section is erected on the bottom and around it. From the upper end of the opposite side wall, there is a non-continuous holding plate for fitting the cassette on the paraffin container, and the interval between the holding plates is the same as or slightly the same as the cassette width. Widely, its top is slightly narrower than the cassette width. By inserting the cassette between the clamping plates, the clamping plates are elastically deformed to widen the gap between the opposing clamping plates, and the elastic repulsion generated thereby. An embedding tray for preparing a histopathological specimen is characterized in that the cassette is sandwiched between clamping plates by force.

According to a third aspect of the present invention, there is provided a pathology according to claim 1 or 2 , characterized in that a locking plate for stopping the sliding of the cassette is erected from the upper end of the side wall where the clamping plate is not erected. Includes an embedding tray for preparation of tissue specimens.

According to a fourth aspect of the present invention, there is provided an embedding tray for preparing a histopathological specimen as set forth in the first or second aspect, wherein a clamping plate is erected on the upper ends of all the side walls.

According to a fifth aspect of the present invention, the sandwiching plate and / or the locking plate are formed low so as not to substantially cover the recording portion of the inserted cassette at least on the side where the recording portion of the cassette is disposed. The content of the embedding tray for preparing a histopathological specimen according to any one of claims 1 to 4 .

Claim 6 of the present invention, the height of the clamping plate and / or locking plate, histopathology specimens according to claim 5, characterized in that more than one-quarter of the height of the cassette fitted The contents are the embedding tray for creation.

Claim 7 of the present invention is characterized in that the sandwiching plate and / or the locking plate are erected only in the vicinity of the corner portion of the paraffin housing portion at least on the side where the recording portion of the cassette is disposed. Item 7. An embedding tray for preparing a histopathological specimen according to any one of Items 1 to 6 .

Claim 8 of the present invention, the cassette support portion is formed at the boundary of the side wall and the clamping plate, claim 1-7 in which the width of the cassette support portion is characterized in that it is a 0.5~2mm The embedding tray for preparation of the histopathological examination specimen described in 1.

Claim 9 of the present invention is the pathological tissue according to any one of claims 1 to 8 , wherein the cassette support part is formed in an inclined shape, and the minimum inclination angle of the cassette support part is 45 ° or more. The embedding tray for preparing test specimens is the content.

A tenth aspect of the present invention includes an embedding tray for preparing a histopathological specimen according to any one of the first to ninth aspects, wherein the shape of the paraffin container is asymmetrical.

In the embedding tray for preparing a pathological specimen of the present invention, a clamping plate for fitting the cassette on the paraffin storage part is erected from the upper end of the opposite side wall, and the cassette is detachable between the clamping plates. It is formed to such an extent that it can be freely fitted. Therefore, when preparing the paraffin block, the cassette is loosely fixed on the embedding tray and does not float by the injection of paraffin.Therefore, not only does the cassette need not be pressed with fingers, but it is easily wrapped after the paraffin is cooled and solidified. The buried tray can be removed. That is, since the cassette is sandwiched without using the local engaging protrusions and depressions, the cassette and the embedding tray can be engaged and disengaged from any direction. For example, you can hold the embedding tray with one hand, hold the cassette with the other hand, and lightly press the cassette against the embedding tray to attach them together. The cassette and the embedding tray can be easily separated by simply applying a force to pry open. Further, it is possible to operate with one hand and one touch depending on the degree of fitting. For example, by placing the cassette on the embedding tray placed on the desk and pressing the cassette lightly with one hand, the cassette is locked on the embedding tray, and the thumb and middle finger are hung on the opposite side walls of the embedding tray. The embedding tray can be removed by lifting the cassette upward (obliquely) with the index finger.
As mentioned above, paraffin does not get burned by fingers, or the embedding tray is not accidentally overturned and the embedding tray is overturned and the desk top is soiled or precious materials are not messed up. Since the cassette can be easily engaged and disengaged, it is safer and more hygienic, the reliability of the inspection is improved, and the workability is dramatically improved.

If the distance between the clamping plate and only slightly narrower than the cassette width, by inserting the cassette into the clamping plates, the spacing is widened clamping plate is slightly elastically deformed, the cassette by its elastic restoring force Since the cassette side is pressed and the cassette is loosely clamped, the embedding tray and the cassette can be easily engaged and disengaged, and the operation with one hand is also facilitated.

  If the gap between the clamping plate bases is the same as or slightly wider than the cassette width and the gap between the clamping plate tops is slightly narrower than the cassette width, the clamping plate will contact the side of the cassette only near the top and press against this part. Therefore, the interval between the clamping plates is easily expanded in accordance with the cassette width. For this reason, it is not necessary to determine the dimensional accuracy of the cassette in detail, and even a cassette with a low dimensional accuracy can be used.

  When the locking plate is erected on the upper end of the side wall where the clamping plate is not erected, even if the cassette slides on the embedding tray, the cassette will come into contact with this locking plate, so it may come off the embedding tray. The workability is further improved.

  When the sandwiching plates are erected on the upper ends of all the side walls, the cassette fitted to the embedding tray is securely held, so that workability is further improved.

  When the sandwiching plate and / or the locking plate are formed low so that the recording portion of the inserted cassette is not substantially covered, the paraffin stays between the sandwiching plate and / or the locking plate and the recording portion of the cassette. However, since the recording part is not hidden, a trimming operation for scraping off the attached paraffin is unnecessary, and the recorded contents can be confirmed easily and reliably.

  The height of the sandwiching plate and / or locking plate is preferably equal to or less than a quarter of the height of the cassette to be fitted. When this is the case, the recording unit is not covered by the sandwiching plate and / or the locking plate, There is substantially no inconvenience that characters or the like written on the recording portion are hidden by the paraffin staying between the sandwiching plate and / or the locking plate and the recording portion.

  When the holding plate and / or the locking plate are erected only in the vicinity of the corner of the paraffin container on the side where the recording portion of the cassette is arranged, the portion where the characters are written, that is, the central portion is the holding plate and / or Or, it is not covered with the locking plate, and the characters and the like described in the recording portion are not hidden by paraffin, so that it is easier to check the description.

  If the cassette support part is formed at the boundary between the side wall and the sandwiching plate and the width of the cassette support part is 0.5 to 2 mm, the paraffin does not stay in this part. Therefore, it is possible to prevent the inconvenience such as hiding the characters and the like, and to easily check the contents of the description and to place the cassette securely. Further, even if the width exceeds 2 mm, the same applies if the cassette support portion is an inclined surface having a minimum inclination angle of 45 ° or more.

  Furthermore, if the shape of the paraffin container is left-right asymmetric, the right and left sides of the specimen can be discriminated by the shape of the paraffin when a microscope specimen is prepared, reducing the risk of sample mix-up and improving the reliability of the inspection. To do.

The embedding tray (hereinafter simply referred to as an embedding tray) for preparing a pathological specimen according to the present invention is used by placing a cassette on the upper end of the paraffin container. In the embedding tray of the present invention, the paraffin container is composed of a bottom part and a side wall erected around the bottom part, and a clamping plate for fitting the cassette on the paraffin container part is discontinuously standing from the upper end of the opposite side wall. The interval between the clamping plates is slightly narrower than the cassette width, or its base is the same or slightly wider than the cassette width, and its top is slightly narrower than the cassette width. The sandwiching plate is elastically deformed by inserting the cassette to widen the gap between the opposing sandwiching plates, and the cassette is sandwiched between the sandwiching plates by the elastic repulsive force generated thereby. And

  The embedding tray of the present invention is made of a heat-resistant material that can withstand liquid (molten) paraffin, and examples of the material include metals such as stainless steel, resins such as polyester, polyamide, polycarbonate, and polyacetal.

  The paraffin housing part is composed of a bottom part and side walls provided around the bottom part. In order to facilitate the demolding of the paraffin block, the side wall is usually tapered from the bottom part toward the opening. In order to further facilitate the demolding, it is preferable that the boundary between the bottom and the side wall and the boundary between the adjacent side walls are rounded.

From the upper end of the opposite side wall, a clamping plate for fitting the cassette on the paraffin housing is erected. In the present invention, the clamping plate holds the cassette on the embedding tray.
In detail, as shown in FIG. 21, first, the cassette C is inserted between the holding plates 6 while sliding along the rounded corners (the arrow pointing downwards in the chain line in FIG. 21). The clamping plate 6 is elastically deformed to widen the gap between the opposing clamping plates 6. As a result, an elastic repulsion force is generated from the clamping plate 6 (the arrow pointing to the right of the chain line in FIG. 21), and the cassette C is embedded between the clamping plates 6 and 6 by using this. Fit into the tray 1.

  In this invention, the space | interval of a clamping plate is formed to such an extent that a cassette is detachably fitted. If this interval is wider than the cassette width, even if the cassette is inserted between the clamping plates, the clamping plate is not elastically deformed, and no elastic repulsive force is generated, so that the cassette is not clamped. Conversely, if it is too narrow, the cassette cannot be inserted between the clamping plates, or if it is forcibly inserted, the elastic repulsion force of the clamping plate is too strong to remove the cassette from the embedding tray.

The appropriate interval between the opposing clamping plates varies depending on the size of the embedding tray and cassette, the elasticity of the material, etc., but cannot be generally specified, but is preferably slightly narrower than the cassette width. If it is about this level, the elastic repulsion force of the clamping plate is also small, the cassette is clamped with a weak force, and the cassette can be attached and detached with one hand, so that the workability is further improved .

Further, the interval between the opposing clamping plates 6 and 6 is the same as or slightly wider than the cassette width at the base, and slightly smaller than the cassette width at the top, that is, as shown in FIG. It can also be in the shape of a slope facing inward. In this case, since the sandwiching plate 6 contacts the side surface of the cassette C only near the top, the force concentrates on this portion and the sandwiching plate 6 is elastically deformed with a slight force, and the interval is increased in accordance with the cassette width. Easy to open. For this reason, the dimensional accuracy of the cassette is not required to be fine, and even a cassette with a low dimensional accuracy can be fitted into the embedding tray.
In addition, when narrowing the space | interval of a clamping plate top part, you may incline only one of the opposing clamping plates, but it is more preferable to incline both inside and it is more preferable to make an inclination angle substantially the same.
Further, it is not necessary for the sandwiching plate to have the appropriate spacing in all the portions, and only a part of the sandwiching plate may have the proper spacing. In other words, the holding plate can be formed by a method in which plate-like members are erected on the top of the side wall at intervals wider than the cassette width, and only a part (for example, the central portion) is bent inward to adjust to an appropriate interval. .

  The sandwiching plate only needs to be able to detachably mount the cassette. Therefore, the sandwiching plate may be provided on one or two sides of a pair of opposing sides of the paraffin container having a substantially rectangular cross section, or may be provided on three sides. Alternatively, it may be provided on all side walls, i.e. on all of the two pairs of sides. When the clamping plates are provided on all the side walls, the cassette is more securely held on the embedding tray and not easily dropped off, and the workability is further improved because the cassette hardly moves on the embedding tray. In this case, when each clamping plate is provided continuously, a cassette having high dimensional accuracy is required, so that each clamping plate is preferably discontinuous (independent).

A locking plate can be erected at the upper end of the side wall where the clamping plate is not erected. When the cassette slides on the cassette support portion, the locking plate abuts against the cassette and stops this movement, thereby preventing the locking plate from falling off the embedding tray.
Unlike the above-described sandwiching plate, this locking plate does not need to be provided on the opposing side walls. For example, the retaining plate is provided on a pair of opposing side walls, and only one of the remaining two side walls is engaged. A stop plate may be provided. When the locking plate is provided only on one side, it is preferable that this embedding tray is used with a cassette fitted so that the recording portion is arranged on the side wall where the locking plate is not provided. In this way, since there is no locking plate in front of the recording unit, even when the cassette is fitted in the embedding tray, it is possible to write characters etc. on the recording unit or read the record with a barcode reader etc. Not only is it easy, but even if the cassette moves due to writing pressure when writing characters or a collision with the recording part of the barcode reader, this cassette will come into contact with the locking plate provided on the back side. Because it stops, it does not fall off from the embedding tray.

  Even when the locking plate is provided on the opposite side wall, the interval is not particularly limited, unlike the sandwiching plate. That is, there may be a slight gap between the locking plate 7 and the cassette C in a state where the cassette C is fitted to the embedding tray 1 (see FIG. 23).

  As described above, both the clamping plate and the locking plate are erected from the upper end of the side wall of the paraffin container. For this reason, when both the clamping plate and the locking plate are provided, or when the clamping plate is erected at the upper ends of all the side walls, these will eventually be provided adjacent to each other. It can also be provided continuously.

The height of the sandwiching plate and / or the locking plate is such that the paraffin deposited on the recording portion is reduced and the characters written on the recording portion are not hidden so that the recording portion is not substantially covered. It is preferable to form it so low. At this time, only the clamping plate and / or the locking plate on the side where the recording unit is arranged may be lowered, or all the clamping plates and / or the locking plates may be lowered.
The specific height of the sandwiching plate may be determined as appropriate according to the size of the cassette, and is not particularly limited. However, in consideration of the size of characters described in the recording unit, the height of the cassette is preferably 4 If it is less than or equal to 1/5, more preferably less than or equal to 1/5, there is little possibility that characters or the like written on the recording part are hidden by paraffin staying between the sandwiching plate and / or the locking plate and the recording part, The recording part is not substantially covered.

  As a method for preventing the characters or the like written on the recording unit from being hidden by paraffin, in addition to the method of lowering the holding plate and / or the locking plate, the holding plate and / or the locking plate may be attached to the corners of the paraffin storage unit. A method of providing only near the portion can be employed. In this case, the paraffin stays between the sandwiching plate and / or the locking plate and the recording portion and covers the corner of the recording portion. However, since the characters are usually written near the center of the recording portion, the paraffin Does not substantially conceal characters or the like described in the recording section, and there is no problem in reading the description. Further, only the holding plate and / or the locking plate on the side where the recording unit is arranged may be erected near the corner, or all the holding plates and / or the locking plates may be provided only near the corner. Also good.

  In the present invention, in order to place the cassette on the paraffin storage part, a cassette support part is formed at the boundary between the side wall and the holding plate. The cassette support is preferably formed narrow or inclined so as not to retain paraffin. In this way, the staying paraffin does not rise on the cassette support part and covers the lower part of the recording part, and therefore, there is no possibility that characters or the like written on the recording part are hidden by the solidified paraffin. Specifically, the width of the cassette support portion is preferably about 0.5 to 2 mm. If it is less than 0.5 mm, the bottom of the cassette may be smaller than the cassette support part due to dimensional errors in manufacturing the cassette or embedding tray, and the cassette may fall into the paraffin container. If the thickness exceeds 2 mm, the paraffin may stay on the cassette support and solidify in a raised state, concealing characters and the like, making it impossible to read the description.

  However, even if it exceeds 2 mm, if this cassette support part is formed in a slope shape, the paraffin slides down along this slope and does not stay, so the letters etc. of the recording part are hidden by the raised and solidified paraffin. There is no fear. In this case, it is preferable that the minimum inclination angle of the cassette support portion is 45 ° or more. If it is less than 45 °, there is a risk that paraffin may stay depending on the width of the cassette support. The upper limit of the tilt angle is not particularly limited. If the tilt angle is smaller than 90 °, the cassette can be placed. However, if the tilt angle is too large, the paraffin container itself becomes too deep and difficult to handle. In practice, it is considered appropriate that the angle is about 10 to 40 ° smaller than the inclination angle of the side wall.

  In the embedding tray of the present invention, the cassette support portion may be provided continuously around the entire circumference, but may be provided intermittently. In this case, since the paraffin slides down from the gap of the cassette support portion, it becomes more difficult to stay and the swell of paraffin is suppressed. More preferably, the cassette support portion is a hemispherical protrusion. In this case, the paraffin slides down on the surface of the hemispherical protrusion, and the swell of paraffin is further suppressed.

You may provide a large cassette support part in each upper-end corner | angular part of a paraffin accommodating part. The shape is not particularly limited as long as the cassette can be placed, but a structure in which the corner portion of the paraffin accommodating portion is slightly indented and the upper end of the triangular portion is the cassette support portion can be exemplified.
Paraffin may rise on this large cassette support and cover the corners of the cassette, but the subject number for identifying the specimen is usually written near the center of the recording unit. Therefore, there is little fear of being hidden by the raised paraffin. However, in order to further reduce this fear, it is preferable that at least the cassette support portion in contact with the side wall on which the recording portion is disposed is as small as possible.

  In order to make the embedding tray of the present invention easy to handle, a gripping portion may be provided on the side wall or the holding plate. Considering the manufacturing process of the embedding tray, the gripping part can be easily provided at the edge of the embedding tray. However, since the paraffin rises on the gripping part, the edge of the side where the recording part of the cassette is not disposed. It is preferable to lay from the edge. In this way, even if the paraffin swells on the grip portion, there is no particular inconvenience because the characters in the recording portion are not hidden.

By making the shape of the paraffin storage part asymmetrical, the right and left of the slice sliced with the microtome are clearly distinguished, so that workability is improved and troubles such as mistaking the specimen due to misidentification of the left and right are prevented. , Improve the reliability of inspection.
The method of making the left-right asymmetry is not particularly limited, but, for example, a method of changing (enlarging) the radius of corners or a method of corrugating the side wall where the recording unit is not arranged can be employed.

  The cassette for creating the paraffin block in the embedding tray of the present invention is not particularly limited as long as it is a cassette having a through hole in the bottom surface of the cassette body. As a typical cassette, an adapter for locking a microtome adapter on the side surface A cassette (FIGS. 24 and 26) provided with a locking part C7 and a cassette (FIGS. 25 and 27) provided with a sloped recording part C3 may be mentioned.

  Hereinafter, the present invention will be described in more detail with reference to the drawings. However, it is needless to say that the present invention is not limited to only the embodiments.

Example 1
As shown in FIGS. 1 to 3, the embedding tray 1 of the present embodiment includes a paraffin container 2 formed from a bottom 3 and a side wall 4 erected around the bottom 3, and a short side of the paraffin container 2. A holding plate 6 erected on the upper end of the side wall 4, a locking plate 7 erected on the upper end of the side wall 4 on the long side, and a gripping portion 8 provided laterally from the upper end of the locking plate 7. . Moreover, as shown in FIG. 1, the clamping plate 6 and the locking plate 7 are provided continuously.
As shown in the partially enlarged view of FIG. 2, the sandwiching plates 6 and 6 are formed in an inwardly inclined shape, that is, the spacing between the sandwiching plate 6 bases is slightly wider than the cassette width, and the spacing between the tops of the sandwiching plates 6 is small. It is slightly narrower than the cassette width. Therefore, when the cassette C is inserted between the sandwiching plates 6 and 6, the sandwiching plate 6 is elastically deformed and its interval is expanded as shown in FIG. 22, and the cassette C is wrapped by the elastic repulsive force of the sandwiching plate 6. It is held on the buried tray 1.
As shown in the partially enlarged view of FIG. 3, the locking plates 7 and 7 are erected vertically, and the interval between them may be substantially the same as the cassette width. In this example, in order to facilitate the insertion of the cassette It is formed slightly wider than the cassette width. For this reason, when the cassette C is fitted to the embedding tray 1, a slight gap is formed between the cassette C and the locking plate 7, as shown in FIG.
As shown in the partially enlarged view of FIG. 4, a cassette support portion 5 is formed at the boundary between the side wall 4 and the holding plate 6. Since the cassette support portion 5 in the present embodiment is a horizontal portion having a narrow width that is laterally provided from the upper end of the side wall 4, the paraffin hardly stays on the cassette support portion 5.

  FIG. 4 is a diagram showing a cross-sectional view of the embedding tray 1 of the present embodiment by a solid line and a sample S and a cassette C by a broken line. The cassette C in FIG. 4 is the same as that shown in FIGS. In the embedding tray 1, as shown by a broken line, the specimen S is put into the paraffin container 2, the cassette body C1 is placed on the cassette support 5, and the side of the cassette body C1 is held by the clamping plate 6. By sandwiching, the cassette C is inserted and used.

  The embedding tray 1 of this embodiment is formed by pressing a stainless steel plate having a thickness of 0.5 mm. The size of the paraffin container is 40 mm × 27.5 mm at the opening, 33.5 mm × 21 mm at the bottom, and 8 mm in height. The height of the sandwiching plate 6 and the locking plate 7 erected at the upper end of the paraffin storage portion 2 is 2 mm, and the gripping portion 8 provided laterally from the upper end is 2 mm × 22 mm. The width of the cassette support portion 5 Is 0.2 mm. Since the height of the cassette C to be used is 8 mm, the height of the sandwiching plate 6 and the locking plate 7 is equal to or less than a quarter of the height of the cassette C (2/8). C3 is not substantially covered by the clamping plate 6 and the locking plate 7.

Example 2
As shown in FIG. 5, the embedding tray 1 of the present embodiment is the same as that of the first embodiment except that only the center portions of the sandwiching plates 6 and 6 are formed in an inwardly inclined shape. In such an embedding tray 1, first, plate-like members are erected vertically from all the side walls 4, and the plate-like member is used as a locking plate 7 for the long side, and the central portion for the short side. Is formed by forming a sandwiching plate 6 by pressing and bending inward to adjust the interval.

Example 3
6 to 8, the embedding tray 1 of the present embodiment includes a paraffin container 2 formed from a bottom 3 and side walls 4 erected around the bottom 3, and all the side walls of the paraffin container 2. 4 includes a holding plate 6 erected in an inwardly inclined shape at the upper end of 4 and a gripping portion 8 provided laterally from the upper end of the holding plate 6 on the long side. The paraffin container 2 in the present embodiment has a shape in which the lower left corner in FIG. 6 is cut out in a substantially triangular shape. As a result, the paraffin container 2 becomes left-right asymmetrical and a microscope specimen is prepared from the paraffin block B. In addition, by looking at the shape of the paraffin P containing the sample S, the direction of the sample S can be determined.
Since the sandwiching plates 6 and 6 are erected from the upper ends of all the side walls 4 as shown in the partial enlarged views of FIGS. 7 and 8, since the cassette C is securely held on the embedding tray 1, Workability is very high.
Except for these points, the present embodiment is the same as the first embodiment.

Example 4
9-12, the embedding tray 1 of a present Example is the long side of the paraffin accommodating part 2 formed from the bottom part 3 and the side wall 4 standingly arranged around it, and the paraffin accommodating part 2 The holding plate 6 erected on the upper end of the side wall 4, the locking plate 7 erected on the upper end of one of the side walls 4 on the short side (the left side in FIG. 9), and the lateral side on the long side The gripping portion 8 is made up of. Moreover, as shown in FIG. 9, the clamping plate 6 and the locking plate 7 are provided continuously.
As shown in the partially enlarged view of FIG. 10, the left side locking plate 7 is formed vertically, and no locking plate is provided on the right side. Further, as shown in the partially enlarged view of FIG. 11, the clamping plates 6 and 6 are provided in an inwardly inclined shape so that the cassette C can be clamped. Furthermore, as shown in the partially enlarged view of FIG. 12, a cassette support portion 5 is formed at the boundary between the side wall 4 and the sandwiching plate 6. Since the cassette support portion 5 in the present embodiment is an inclined surface having an inclination angle of about 45 °, the paraffin P flows down along the inclined surface and does not easily stay on the cassette support portion 5.

  FIG. 12 is a diagram showing a cross-sectional view of the embedding tray 1 of the present embodiment by a solid line and a sample S and a cassette C by a broken line. The cassette C in FIG. 12 is the same as that shown in FIGS. The embedding tray 1 has the sample S placed in the paraffin container 2 as shown by the broken line, and the recording unit C3 is disposed on the side (right side) where the locking plate 7 is not erected. The C1 is placed on the cassette support 5 and the cassette C is fitted and used by holding the side surfaces of the cassette C with the holding plates 6 and 6 erected on the long side.

  The embedding tray 1 of this example is substantially the same as that of Example 1 except that there is no locking plate 7 on the right side in FIG. 12, but the height of the cassette C to be used is 6 mm, The heights of the sandwiching plate 6 and the locking plate 7 are at least a quarter (2/6) of the height of the cassette C. However, since the locking plate 7 or the like is not erected on the side where the recording unit C3 is disposed, the paraffin P does not stay between the recording unit C3 and the locking plate 7 unlike the other sides. The written characters are not hidden. Further, even when characters or the like are entered in the recording section C3 while the cassette C is held on the embedding tray 1, and the cassette C slides due to the writing pressure, the cassette C is provided with the locking plate 7 provided on the left side. The cassette C does not fall off from the embedding tray 1 because the movement is stopped by abutting against the embedding tray 1.

Example 5
13 to 16, the embedding tray 1 of the present embodiment includes a paraffin container 2 formed from a bottom 3 and a side wall 4 erected around the bottom 3, and a long side of the paraffin container 2 The holding plate 6 is erected on the upper end of the side wall 4, the locking plate 7 is erected on the upper end of the side wall 4 on the short side, and the gripping portion 8 is provided on the long side. Moreover, as shown in FIG. 13, the clamping plate 6 and the locking plate 7 are provided continuously on the left side.
As shown in the partially enlarged view of FIG. 14, a relatively high locking plate 7 is erected vertically on the left side, and a lower locking plate 7 is erected vertically on the right side. Further, as shown in the partially enlarged view of FIG. 15, the sandwiching plates 6 and 6 are provided in an inwardly inclined shape so that the cassette C can be sandwiched therebetween. The low locking plate 7 is provided only at the center of the right side in FIG. 13 (the front side in FIG. 15). Further, as shown in the partially enlarged view of FIG. 16, an inclined cassette support portion 5 having an inclination angle of 45 ° is formed at the boundary between the side wall 4 and the sandwiching plate 6.

  FIG. 16 is a diagram showing a cross-sectional view of the embedding tray 1 of the present embodiment by a solid line and a sample S and a cassette C by a broken line. The cassette C in FIG. 16 is the same as that shown in FIGS. In the embedding tray 1, as shown by a broken line, the specimen S is put into the paraffin container 2, and the recording unit C3 is arranged on the side where the low locking plate 7 is erected (the right side in FIG. 16). Then, the cassette body C1 is placed on the cassette support portion 5 and sandwiched between the clamping plates 6 and 6 erected on the long side, whereby the cassette C is fitted and used.

  The size of the embedding tray 1 of this embodiment and the height of the cassette C to be used are substantially the same as those of the embodiment 4, but on the right side in FIG. 16, that is, the side where the recording unit C3 is arranged. The only difference is that the locking plate 7 is erected. However, since the height of the locking plate 7 erected on the right side is 1 mm, it is equal to or less than a quarter (1/6) of the height of the cassette C to be fitted, and the recording portion C3 is substantially In particular, it is not covered with the locking plate 7.

Example 6
17 to 20, the embedding tray 1 of the present embodiment includes a paraffin container 2 formed from a bottom 3 and a side wall 4 standing around the bottom 3, and a long side of the paraffin container 2. The holding plate 6 is erected on the upper end of the side wall 4, the locking plate 7 is erected on the upper end of the side wall 4 on the short side, and the gripping portion 8 is provided on the long side. Moreover, as shown in FIG. 17, the clamping plate 6 and the locking plate 7 are provided continuously.
In this embodiment, the lower locking plate 7 on the right side in FIG. 17 (front side in FIG. 19) is provided in the vicinity of the corner, and also on the right side in FIG. Is the same as that of Example 5 except that is continuously provided.

  FIG. 20 is a diagram showing a cross-sectional view of the embedding tray 1 of the present embodiment by a solid line and a sample S and a cassette C by a broken line. The cassette C in FIG. 20 is the same as that shown in FIGS. In the embedding tray 1, as shown by a broken line, the specimen S is put into the paraffin container 2, and the recording unit C3 is arranged on the side where the low locking plate 7 is erected (the right side in FIG. 20). Then, the cassette body C1 is placed on the cassette support portion 5, and the cassette body C1 is sandwiched between the clamping plates 6 and 6 provided on the long side, so that the cassette C is fitted and used.

  In the embedding tray 1 of the present embodiment, since the low locking plate 7 is erected only near the corner of the right side (side where the recording unit C3 is arranged), the center portion, that is, the character or the like is described. The portion is not covered at all by this locking plate 7. For this reason, the paraffin P does not adhere to the characters and the like, and accordingly, the characters and the like described in the recording unit C3 are not hidden, so that the described contents can be read reliably.

  As described above, the embedding tray for preparing the histopathological specimen of the present invention is prepared so that the cassette is detachably fitted to the upper part of the paraffin container of the embedding tray, so that a paraffin block is created. In this case, it is not necessary to hold the cassette with a finger to prevent the cassette from being lifted by paraffin, and the cassette and the embedding tray can be easily detached and attached with one hand with one touch. Therefore, the workability for preparing the histopathological specimen and the reliability of the examination are greatly improved, and its usefulness is greatly increased.

It is a top view which shows Example 1 of the embedding tray of this invention. 1 is a front view of Example 1. FIG. 1 is a side view of Example 1. FIG. It is AA sectional drawing of Example 1 (FIG. 1). It is a top view which shows Example 2 of the embedding tray of this invention. It is a top view which shows Example 3 of the embedding tray of this invention. 6 is a front view of Example 3. FIG. 6 is a side view of Example 3. FIG. It is a top view which shows Example 4 of the embedding tray of this invention. 10 is a front view of Example 4. FIG. 10 is a side view of Example 4. FIG. It is BB sectional drawing of Example 4 (FIG. 9). It is a top view which shows Example 5 of the embedding tray of this invention. 10 is a front view of Example 5. FIG. 10 is a side view of Example 5. FIG. It is CC sectional drawing of Example 5 (FIG. 13). It is a top view which shows Example 6 of the embedding tray of this invention. 10 is a front view of Example 6. FIG. It is a side view of Example 6. It is DD sectional drawing of Example 6 (FIG. 17). It is explanatory drawing which shows the state of the clamping board at the time of attaching a cassette to the embedding tray of this invention. It is explanatory drawing which shows the state of the clamping board at the time of attaching a cassette to another embedding tray of this invention. It is explanatory drawing which shows the state of the latching plate at the time of fitting a cassette in the embedding tray of this invention. It is a perspective view which shows the example of the cassette used with the embedding tray of this invention. It is a perspective view which shows the other example of a cassette. It is sectional drawing which shows the state which put the test substance in the cassette. It is sectional drawing which shows the state which put the test substance in the cassette. It is a perspective view which shows the example of the conventional embedding tray. It is explanatory drawing which shows the preparation methods of a microscope sample using the conventional embedding tray. It is explanatory drawing which shows the preparation methods of a microscope sample using the conventional embedding tray. It is explanatory drawing which shows the preparation methods of a microscope sample using the conventional embedding tray. It is explanatory drawing which shows the preparation methods of a microscope sample using the conventional embedding tray. It is explanatory drawing which shows the preparation methods of a microscope sample using the conventional embedding tray. It is explanatory drawing which shows the embedding method of the embedding tray and cassette which is not preferable.

DESCRIPTION OF SYMBOLS 1 Embedding tray 2 Paraffin accommodating part 3 Bottom part 4 Side wall 5 Cassette support part 6 Clamping plate 7 Locking plate 8 Grasping part C Cassette C1 Main body C2 Lid C3 Recording part C4 Through-hole C5 Engagement protrusion P Paraffin S Specimen T Conventional tray T1 bottom part T2 cassette support part T3 cassette locking part T4 frame part T5 grip part T6 engagement recess B paraffin block

Claims (10)

An embedding tray for preparing a histopathological specimen that is used by placing a cassette on the upper end of a paraffin container, wherein the paraffin container is composed of a bottom part and a side wall erected around the bottom part. From the upper end, a holding plate for fitting the cassette onto the paraffin container is discontinuously erected, and the interval between the holding plates is slightly narrower than the cassette width. By inserting the cassette between the holding plates, Pathological examination specimen preparation characterized in that the cassette is sandwiched between the clamping plates by elastically deforming the clamping plates to widen the gap between the opposing clamping plates and the elastic repulsive force generated thereby Embedding tray. An embedding tray for preparing a histopathological specimen that is used by placing a cassette on the upper end of a paraffin container, wherein the paraffin container is composed of a bottom part and a side wall erected around the bottom part. From the upper end, a holding plate for fitting the cassette onto the paraffin container is discontinuously erected, and the interval between the holding plates is the same as or slightly wider than the cassette width, and the top portion is slightly larger than the cassette width. By inserting the cassette between the sandwiching plates, the sandwiching plates are elastically deformed to widen the interval between the opposing sandwiching plates, and the cassette is sandwiched between the sandwiching plates by the elastic repulsive force generated thereby. An embedding tray for preparing a histopathological specimen is characterized by being configured as described above.   The embedding for preparing a histopathological specimen according to claim 1 or 2, wherein a locking plate for stopping the sliding of the cassette is provided from the upper end of the side wall on which the holding plate is not erected. tray.   The embedding tray for preparing a histopathological specimen according to claim 1 or 2, wherein a clamping plate is erected on the upper ends of all the side walls.   2. The sandwiching plate and / or the locking plate are formed low so as not to substantially cover the recording portion of the inserted cassette at least on the side where the recording portion of the cassette is disposed. An embedding tray for preparing a histopathological specimen according to any one of -4.   6. The embedding tray for preparing a histopathological specimen according to claim 5, wherein the height of the sandwiching plate and / or the locking plate is equal to or less than a quarter of the height of the cassette to be fitted.   The sandwiching plate and / or the locking plate are erected only in the vicinity of the corner of the paraffin container at least on the side where the recording portion of the cassette is disposed. An embedding tray for preparing the histopathological specimen described.   8. A histopathological specimen preparation according to any one of claims 1 to 7, wherein a cassette support part is formed at the boundary between the side wall and the clamping plate, and the width of the cassette support part is 0.5 to 2 mm. Embedding tray.   The embedding tray for preparing a histopathological specimen according to any one of claims 1 to 8, wherein the cassette support part is formed in a slope shape, and the minimum inclination angle of the cassette support part is 45 ° or more. .   The embedding tray for preparing a histopathological specimen according to any one of claims 1 to 9, wherein the shape of the paraffin container is asymmetrical.

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